studies using qol instruments to assess outcome in patients with bd
Báo cáo khoa học: "Transarterial chemoembolisation (TACE) using irinotecan-loaded beads for the treatment of unresectable metastases to the liver in patients with colorectal cancer: an interim report" pdf
... patients treated with patients treated with beads with liver dominant hepatic metastasis after ingDisease Free Survival failing standardSurvival ofIrinotecan drug elutingIrinotecan drug eluting ... Y: Biodegradable mitomycin C microspheres given intra-arterially for inoperable hepatic cancer With particular reference to a comparison with continuous infusion of mitomycin C and 5-fluorouracil ... hemoglobin, and platelet count), and clinical chemistry (ALT, AST, total bilirubin, prothrombin time, and alkaline phosphatase) All toxicities were carefully monitored Clinicopathologic data along with...
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Báo cáo y học: " Formation of translational risk score based on correlation coefficients as an alternative to Cox regression models for predicting outcome in patients with NSCLC" doc
... combination of numerous clinical data concerning the individual patient, particularly information relating to biomarkers However, translational integration of this large amount of information into ... time In Table the patients are divided into the three groups with clear prognostic assignment according to their individual ISIR-score, i.e survival ≤ 12, between Figure Immunohistological staining ... (1-specificity) rates of the introduced formula applied to patients with non-small cell lung carcinoma: theoretical reference line of no discrimination, thin continuous; ROCs using T-, N-, M-status,...
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Báo cáo y học: "Acute and delayed mild coagulopathy are related to outcome in patients with isolated traumatic brain injury" docx
... finding in patients with isolated TBI and suggested that alcohol intoxication is associated with a lower incidence of coagulopathy as compared to non-intoxicated patients [28] Early hemostatic monitoring, ... monitoring, including point-of-care thromboelastography or thromboelastometry, may contribute to early diagnosis of coagulation disorders in patients with isolated head injury Although data regarding ... INR: international normalized ratio; IQR: interquartile range; ISS: injury severity score; PAI-1: plasminogen activator inhibitor; OR: odds ratio; PT: prothrombin time; TBI: traumatic brain injury...
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Báo cáo sinh học: "Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib" potx
... (95% CI) Endpoint, soluble protein, and time point Median ratio to baseline Median time to event, weeks Patients with ≤ median ratio to baseline† Patients with > median ratio to baseline† TTP VEGF-A ... points in patients with high VEGF-C concentrations at baseline, with little change in patients with low baseline VEGF-C This finding is consistent with the positive associations between clinical ... multitargeted tyrosine kinase inhibitor with antiangiogenic activity in vivo, has been investigated in advanced HCC within several phase II trials [13-15], and a phase III trial comparing sunitinib with sorafenib...
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báo cáo hóa học:" Mechanism-related circulating proteins as biomarkers for clinical outcome in patients with unresectable hepatocellular carcinoma receiving sunitinib" pot
... (95% CI) Endpoint, soluble protein, and time point Median ratio to baseline Median time to event, weeks Patients with ≤ median ratio to baseline† Patients with > median ratio to baseline† TTP VEGF-A ... points in patients with high VEGF-C concentrations at baseline, with little change in patients with low baseline VEGF-C This finding is consistent with the positive associations between clinical ... multitargeted tyrosine kinase inhibitor with antiangiogenic activity in vivo, has been investigated in advanced HCC within several phase II trials [13-15], and a phase III trial comparing sunitinib with sorafenib...
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Báo cáo y học: "Advanced glycation end-product (AGE)-damaged IgG and IgM autoantibodies to IgG-AGE in patients with early synovitis." ppt
... cross-link proteins (e.g pentosidine, which links a lysine to an arginine on separate proteins) Hemoglobin-AGE (HbA1c) is the best studied glycated protein [4] and has been shown to correlate with ... cross-links that form in cartilage due to pentosidine, which cause the typical yellowing [12], are thought to contribute directly to the joint pathology and increases in urinary AGE detected in patients ... tenderness or swelling in each of the joints examined Sacroiliitis was defined on the basis of having a history of persistent inflammatory low back or buttock pain in conjunction with tenderness...
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Báo cáo khoa học: "Can prophylactic breast irradiation contribute to cardiac toxicity in patients with prostate cancer receiving androgen suppressing drugs?" ppt
... from choosing MeV In and individuals, 12 MeV were necessary to cover the pre-pectoral region adequately In the prostate cancer patients, MeV was appropriate in cases, MeV in cases, 12 MeV in cases ... depending on the anatomical situation, left-sided PMRT might lead to a certain exposure of the heart to ionizing radiation Typically, single electron beams with a sharp dose gradient are used, having ... ventricle with the CT protocols used in these patients In general, the highest doses to the heart were seen in the anterior part of the left ventricle and the interventricular septum (Figure 3) Up to...
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Báo cáo y học: "Lung abscess predicts the surgical outcome in patients with pleural empyem" pdf
... clinical presentation, but leukocytosis There were more patients with leukocytosis in lung abscess group There were 21 (96%) patients with leukocytosis in the abscess group Only 150 (63%) patients ... complication (n = 4, 1.5%) Two patients were converted to mini-thoracotomy (2 of 259, 0.77%) In abscess group, there were nineteen phase II patients and three phase III patients In non-abscess group, ... due to respiratory failure or unstable vital signs In abscess group, there was only one patient cared in intensive care unit In non-abscess group, there were 13 patients cared in intensive care...
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Báo cáo y học: "Persistence and compliance to antidepressant treatment in patients with depression: A chart review" doc
... depression in the clinical outpatient setting Porer compliance to medications in patients with depression than in those with schizophrenia or epilepsy points to a necessity of targeting the medication ... compliance to antidepressant drugs in outpatients with a major depressive disorder in psychiatric clinics in Tokyo, Japan We also tried to assess the effects of demographic and clinical characteristics ... the first study that investigates persistence and compliance to antidepressants in patients with a major depressive disorder in the clinical outpatient setting Notwithstanding the limitations...
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Báo cáo y học: "Alterations in the muscle-to-capillary interface in patients with different degrees of chronic obstructive pulmonary disease" pps
... altered in COPD patients [8,9,13] This finding can be explained by a reduction in fibre area as previously shown in COPD patients [10] This is also in line with a previous study [9] indicating a ... fibres in the tibialis anterior muscle of patients with COPD [10] This is in line with previous studies [3,7-9] and together with previous findings of a decrease in oxidative enzyme activities in ... to our findings may be a reduced mitochondrial volume of the muscle fibre This explanation would be in line with a recent study showing a decrease in mitochondrial volume in patients with COPD...
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Báo cáo y học: "A randomized, double-blind study of AMG 108 (a fully human monoclonal antibody to IL 1R1) in patients with osteoarthritis of the knee" pdf
... analyzed from lowest to highest baseline pain tertile, differences in pain score change from baseline increased from -17.0 to -65.0 to -109.5 with AMG 108, while with placebo, it remained at approximately ... additional endpoints included the PK of AMG 108 In Part B, the primary endpoint was the clinical efficacy of AMG 108 (change from baseline to week in the WOMAC pain score); additional endpoints included ... endpoint included all Part B randomized patients who participated in the WOMAC study (n=145) The primary endpoint was the change in the WOMAC pain score from day to week in patients administered...
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Báo cáo y học: " Private specificities can dominate the humoral response to self-antigens in patients with cryptogenic fibrosing alveolitis " pps
... or pan-inspiratory crackles, with or without clubbing; the absence of clinical, radiological or laboratory evidence of any other ILD; no exposure to agents that are known to be able to induce ... reports In order to determine the specificity and diversity of autoantibodies in patients with CFA, we used western blots Patients sera were applied to blots derived from cell lines that had originated ... immunoglobulin-binding protein (IGBP1) gene, which has sequence similarity to the yeast protein (TAP42) primary research Molecular cloning of antigens associated with cryptogenic fibrosing alveolitis...
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Báo cáo khoa học: "parison between logistic regression and neural networks to predict death in patients with suspected sepsis in the emergency room" ppsx
... (recorded in 36% of patients) , followed by soft tissue infection (17%), intra-abdominal infection (12%), urinary tract infection (11%) and others (11%); sepsis of undetermined source was recorded in ... Missing data for continuous variables were estimated with simple imputations using the median nonmissing value In total, estimation procedures were performed in 2.6% (14 simple records) of baseline ... et al Table Cutoff points on continuous variables for changes in the probability of death according to locally weighted regression Variable Cutoff points Respiratory rate (breaths/min)
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Báo cáo khoa học: "Bench-to-bedside review: Adjuncts to mechanical ventilation in patients with acute lung injury" docx
... flow coincides with the beginning of the inspiratory flow In (c) the respiratory rate has been increased excessively and causes intrinsic positive end-expiratory pressure: the inspiratory flow ... expiratory flow ends 0.5 s before the inspiratory flow In (b) the respiratory rate has been increased without generating intrinsic positive end-expiratory pressure: the end of the expiratory flow ... carina and incorporating an internal side port opening in the internal lumen cm above the distal tip [16,29] A flow sensor connected to the inspiratory limb of the ventilator gives the signal to...
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Báo cáo y học: "How can the response to volume expansion in patients with spontaneous respiratory movements be predicted" ppsx
... CI is not due to insufficient fluid loading Conclusion In patients with spontaneous respiratory movements, ∆PP and inspiratory variations in RAP failed to predict the response to volume expansion ... variation and inspiratory variation in RAP failed to predict the response to fluid challenge in patients with spontaneous respiratory movements • In the absence of a clear cut off value allowing reliable ... are the following Which indices can be used to predict fluid responsiveness in patients with respiratory movements [9]? In particular, can dynamic indexes of preload be useful in this context?...
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Báo cáo khoa học: "ffect of induction agent on vasopressor and steroid use, and outcome in patients with septic shock" ppsx
... is not influenced by induction agent • Outcome related to pre-existing risk is not different if etomidate is used for induction • Outcome is not improved if steroids are administered to patients ... (20 to 180) mg; thiopental, 200 (75 to 450) mg; and midazolam, (2 to 3) mg Eighty-four patients were intubated in the ICU and 75 were intubated in areas outside the ICU, mostly in an operating ... department One hundred forty-nine (94%) patients were intubated within six hours of ICU admission and eight others were intubated within 24 hours of admission All 159 patients were intubated because of...
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Báo cáo y học: "Role of COX-2 in cough reflex sensitivity to inhaled capsaicin in patients with sinobronchial syndrome" ppsx
... treatment with a potent COX-2 inhibitor, etodolac, increased the cough threshold to inhaled capsaicin in stable patients with sinobronchial syndrome No difference could be found in the baseline pulmonary ... treatment with a potent COX-2 inhibitor, etodolac, attenuated cough reflex sensitivity to inhaled capsaicin in patients with sinobronchial syndrome This is the first report indicating the modulating ... can be induced by various stimuli, including inflammatory cytokines, resulting in further production of inflammatory substances such as prostanoids [6,7] Previous study suggested that the induction...
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Báo cáo y học: "A positive fluid balance is associated with a worse outcome in patients with acute renal failure" ppsx
... To analyze further the determinants of mortality and fluid balance in patients with ARF, we divided the patients into two groups according to urine output and treatment with RRT In oliguric patients ... demonstrated that mean fluid balance was an independent determinant of ICU outcome in patients with acute lung injury/adult respiratory distress syndrome In patients with sepsis, the relation between a ... compared with Another interesting finding in the present study is that outcome among patients treated with RRT was better when RRT was started early in the course of the ICU stay Although in the...
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Báo cáo y học: "Association of HMGB1 polymorphisms with outcome in patients with systemic inflammatory response syndrome" ppsx
... Polymorphisms in innate immune receptors and in both proinflammatory and anti-inflammatory cytokines have been extensively studied in relation to SIRS and sepsis (reviewed in [5]) In the present ... levels tended to increase when moving from patients with only SIRS to patients with sepsis of increasing severity, although only reaching a near-significant level (P = Table Patient baseline characteristics ... become apparent in disease settings The finding of lower HMGB1 levels in patients with a higher risk of mortality during their early disease course was surprising, but is in line with reports where...
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Báo cáo y học: "he Nordic Subpopulation Research Programme: prediction of treatment outcome in patients with low back pain treated by chiropractors - does the psychological profile matter" pps
... Participating patients Consecutive patients who sought care for LBP with or without pain radiating into the leg, who were new to the clinic or had not received chiropractic treatment within the ... only at base-line (drop-outs) Outcome at the 4th visit was dichotomized into "good outcome" (definitely better) and "not good outcome" (all other options including missing answer) Outcome at months ... base-line in relation to outcome at the 4th visit The same base-line variables were used as predictor variables in relation to outcome at months with the addition of two variables obtained at...
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Tìm thêm: khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose