set the controls for the heart of the sun chord
The Female Brain is one of the most-talked-about books of the year. ppt
... irth of the F emale B rain glanced at their mothers’ faces. They frequently touched the forbid-den toy cow, even though their mothers shouted, “No!” The one-year-old boys, driven by their ... to get to the clothes hanging in their closets. One girl had a pink two-piece outfit, and the other had a green two-piece outfit. Their mother giggled every time she’d see them switch the tops—pink ... adjoined each other. The sandbox was in our yard, and the swing set straddled the invisible line that divided our properties. Our mothers, who soon became friends, saw the advantage of their two...
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Báo cáo khoa học: Interaction of the E2 and E3 components of the pyruvate dehydrogenase multienzyme complex of Bacillus stearothermophilus ppt
... representing the PSBD of the dihydrosuccinyltransferase chain of the 2-oxoglutarate dehydrogenase complex of E. coli [12]and of the dihydroacetyltransferase chain of the PDHcomplex of B. stearothermophilus ... 119–171) of the B. stearothermophilusE2p polypeptide chain with the dimer of a proteindomain (E3int) representing the interface domain (resi-dues 343–470) of B. stearothermophilus E3. The use of the ... probably due to the use of uniformly15N-labelled PSBD and the inclusion of additional resi-dues in the construct at the N-terminus of the domain.In particular, the absence of residues Arg127...
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Tài liệu Cancer Pain Management: A perspective from the British Pain Society, supported by the Association for Palliative Medicine and the Royal College of General Practitioners docx
... from cancer at any stage of the disease with the hope of raising awareness of the types of therapies that may be appropriate and increasing awareness of the role of the pain specialist in cancer ... enlargement of the liver results in the capsule being stretched at the point of the sensory innervation In general, unless there is gross hepatic dysfunction, the metabolism of the common drugs in the ... understanding of their condition.ã what the pain means to the individual and their family.ã how the pain may impact upon relationships within the patients family.ã whether the pain inuences the patients...
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Báo cáo khoa học: b-Secretase cleavage is not required for generation of the intracellular C-terminal domain of the amyloid precursor family of proteins pot
... in both the peripheraland central nervous systems [6]. In the former, theyare involved in the formation and correct functioning of the neuromuscular junction [9], and in the latterthey have ... levels of soluble APP remaining constantirrespective of the presence or absence of BACE1. The levels of APPsa increased to account for the loss of APPsb (soluble C-terminally truncated b-cleaved form of ... (Fig. 5B). As was the case for FLAPP, the differences seen in the levels of FLAPLP1 are not due to a difference in the levels of APLP1 mRNA (Fig. S6B). Importantly, the ratio of mature to immature...
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Tài liệu THE HISTORY OF THE RISE, PROGRESS, AND ACCOMPLISHMENT OF THE ABOLITION OF THE SLAVE-TRADE pdf
... his foreign dominions was the readiest way of converting them to the principles of the Christian religion. These, then, were the first forerunners in the great cause of the abolition of the ... held the reigns of the government of Spain till Charles the Fifth came to the throne, for the establishment of a regular system of commerce in the persons of the native Africans. The object of ... consigning to it those of another. Ximenes, therefore, may be considered as one of the first great friends of the Africans after the partial beginning of the trade. This answer of the cardinal, as...
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Tài liệu Đề tài " Asymptotic faithfulness of the quantum SU(n) representations of the mapping class groups " pdf
... separate the mapping torus of the identity from the rest of the mapping tori as a purelyTQFT consequence of Corollary 1.In this paper we have initiated the program of using of the theory of Toeplitz ... writeρk= ρn,dkthroughout the rest of the paper.Our key idea in the proof of Theorem 1 is the use of the endomorphismbundle End(Vk) and the construction of sections of this bundle via Toeplitzoperators ... manifolds, in particular their formula for the asymptotics in k of the operator norm of Toeplitz operators and the asymptotic expansion of the product of two Toeplitz operators. Using these results we...
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Tài liệu Báo cáo khoa học: The sensor protein KdpD inserts into the Escherichia coli membrane independent of the Sec translocase and YidC doc
... by the protease, only a smallshift of the molecular mass of the protein is expectedbecause the antibody recognizes the remaining C-terminaldomain. In the presence of YidC, the shift of the ... follow the translocation of the second periplasmicloop. The results show that neither the Sec translocase nor the YidC protein are required for membrane insertion of the second loop of KdpD. ... of 2.5 lLofCCCP(10 mM) for 45 s, prior to labelling of the cells.ResultsMembrane insertion of the KdpD protein The membrane insertion of the KdpD protein is difficult toanalyse because the...
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Báo cáo khoa học: Structural mobility of the monomeric C-terminal domain of the HIV-1 capsid protein pptx
... responsible, from a thermodynamic point of view, for the binding of the monomeric species of CAC?We have previously discussed the variation in the freeenergy of binding as a function of the changes ... in the monomeric structure of CAC,and (b) the inherent flexibility for the majority of the residues. Thus, the conformational entropy appears tobe distributed through the whole structure of the ... (i.e. the spectral density function at the Larmor frequency of the 15N) and J(0.87xH) (i.e. the spectral density function at the 0.87 times the Lar-mor frequency of the 1H) are independent of...
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Báo cáo khoa học: Solution structure of the active-centre mutant I14A of the histidinecontaining phosphocarrier protein from Staphylococcus carnosus ppt
... protocol used for the calculations. Therefore, we recalculated the structure of the w ild-type protein on the b asis of the restraints usedpreviously [15] with the same protocol used here for the mutant ... wascomputed as the ratio of the s tandard deviations of the chemical shifts of the amide nitrogen and p roton nuclei.ResultsDetermination of the three-dimensional structure of HPr(I14A)To allow the comparison ... parallel to the a-helices and the b-sheet of the protein. As the 1HN-15Nbond vectors in the a-helices are therefore almost parallel to the z-axis, their size is mainly determined by the positiveeigenvalue...
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Adventurers of the Far North A Chronicle of the Frozen Seas doc
... another the weapons of their common stock. The advance was made in the middle of the night, but at this season of the year the whole {60} scene was brilliant with the light of the midnight sun. ... below zero at noon of the brief three-hour day in the heart of winter.Sunday was a day of rest. The officers dressed in their best attire. Franklin read the service of the Church of England to his ... search of the missing ships. The efforts of the governmentwere seconded by the munificence of private individuals, and by the generosity of naval officers who gladlygave their services for no other...
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Báo cáo khoa học: Structure–function analysis of the filamentous actin binding domain of the neuronal scaffolding protein spinophilin pot
... necessarily represent the of cial views of the National Institute of Neurological Disorders andStroke or the National Institutes of Health. WP is the Manning Assistant Professor for Medical Science ... description of the molecular components involved in the regulation andmaintenance of dendritic spine morphology is funda-mental to our understanding of the functions of the central nervous system. The ... [38]. In the presence of theseABD constructs, the concentrations of fluorescentactin polymers appeared to be higher because of the precipitation of crosslinked actin polymer networksonto the glass...
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Báo cáo Y học: A functional role of the membrane-proximal extracellular domains of the signal transducer gp130 in heterodimerization with the leukemia inhibitory factor receptor pot
... corresponding domain of the GCSFR. The replacement is assumed to compensate for the shift of the ligand-binding epitopes of the receptors. The domainarchitecture of GCSFR is identical to that of gp130;moreover ... a copre-cipitation of gp130 with LIFR independently of the lysisbuffer used for the disintegration of the cells (data notshown). Because of the high expression levels of the transiently transfected ... heterocomplex of gp130and LIFR depends on the binding of a cytokine (e.g. LIF).Site II of the ligand contacts the CBM of gp130 [14,15],while site III contacts the Ig-like domain of the LIFR [13].In the...
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rock v pop music of the 1970 s v music of the 1990 s
... came the dawn of new instruments such asdrums, pianos, flutes, and guitars (Romeu 1). Both eras of rock usedthese types of musical instruments in one way or the other. They are the essentials of ... the developing culture of the seventies. Bands often used their popularity to spread their feelingson such topics. They were, and still are, the central of communicationbetween all genres of ... timewhere they address war, and the feeling of fighting for what is right wasoften found in lyrics. Many people believed that the classic rock groupswere bad for the soul or included the use of mind-altering...
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