safety efficacy and contraindications of spices
Báo cáo y học: "Ablation of atrial fibrillation with the Epicor system: a prospective observational trial to evaluate safety and efficacy and predictors of success" pptx
... suffered in 20% of cases of paroxysmal, in 37% of persistent, and in 41% of cases of long standing persistent AF There was no statistical significant correlation in between type of AF and diagnosis ... without the need of large thermal gradients and without jeopardizing adjacent structures (Figure 1) [6] The purpose of this study was to evaluate the efficacy of left atrial HIFU ablation of AF with ... Diagnosis and classification of AF were established by standard ECG and holter ECG in all patients prior to admission AF was defined paroxysmal in 29%, persistent in 31% and long standing persistent...
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Báo cáo y học: "omparative Efficacy and Tolerability of 5-Loxin® and Aflapin® Against Osteoarthritis of the Knee: A Double Blind, Randomized, Placebo Controlled Clinical Study"
... comparative efficacy and tolerability of 5-Loxin® and Aflapin® in the treatment of OA of the knee Materials and Methods Study materials BE-30 (5-Loxin) is a novel Boswellia serrata extract standardized ... Hematological and biochemical evaluations For assessment of safety of 5-Loxin® and Aflaseveral parameters were evaluated in serum, urine and whole blood of all subjects at each visit of the study ... software to evaluate the efficacy of 5-Loxin® and Aflapin® in comparison with the placebo group in terms of improvement in pain and physical function scores at baseline and on days 7, 30, 60 and...
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báo cáo hóa học:" Poor Efficacy and Tolerability of Stavudine, Didanosine, and Efavirenz-based Regimen in Treatment-Naive Patients in Senegal" potx
... http://www.jiasociety.org/content/9/4/7 Respectively, 47% and 53% of patients were at CDC stages B and C Seven of the patients at CDC stage C had a history of pulmonary tuberculosis, and had a history of extrapulmonary tuberculosis ... 14:1601-1610 Abstract Gerstoft J, Kirk O, Obel N, et al.: Low efficacy and high frequency of adverse events in a randomized trial of the triple nucleoside regimen abacavir, stavudine and didanosine AIDS ... resourcelimited countries and is now used by hundred of thousands of patients worldwide However, d4T is no longer recommended in Western countries because of its longer-term toxicity profile that includes,...
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Báo cáo hóa học: " The efficacy and value of emergency medicine: a supportive literature review" pdf
... one aspect of EM efficacy Efficacy of EM for critical care and procedures Efficacy of EM for efficiency or cost of care Efficacy of EM for public health and preventive medicine Efficacy of EM for ... accuracy of reading films, etc.) Efficacy of EM for trauma and airway management Efficacy of EM for using ultrasound Efficacy of EM faculty Efficacy of EM residencies Overviews and editorials of EM efficacy ... efficacy or value of EM or aspects of EM delivered care Case reports and case series of successful clinical care in the Emergency Department (ED) were not included (there are of course thousands...
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Báo cáo y học: " Comparative efficacy and acceptability of methylphenidate and atomoxetine in treatment of attention deficit hyperactivity disorder in children and adolescents: a meta-analysis" pdf
... established its efficacy in treatment of ADHD [10] Tricyclic antidepressants and bupropion are other non-stimulants which are effective in treatment of ADHD [11] Efficacy of both methylphenidate and atomoxetine ... form Title, year of publication, total number of participants, age of participants, design of study (parallel vs crossover), blinding, name and dose of drug, number who dropped out and outcome measures ... out using the randomeffects model of DerSimonian and Laird [25] The presence of heterogeneity between studies was tested using We included all published randomized, open label and double blind...
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báo cáo khoa học: " Efficacy and tolerability of intravenous methylergonovine in migraine female patients attending the emergency department: a pilot open-label study" pdf
... Authors' contributions AINM, GCG and WMB diagnosed and treated patients EPC and FR participated in the design of the study and drafted the manuscript All authors read and approved the manuscript's ... extending European principles of management Intern Emerg Med 2008, 3(Suppl 1):S17-S24 Saper JR, Silberstein S: Pharmacology of dihydroergotamine and evidence for efficacy and safety in migraine Headache ... analysis of variance was applied to analyze the evolution of pain severity, systolic and diastolic blood pressure, and heart rate Effects sizes were caluculated according to the Cohen's formula and...
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Characterization of CMX 13 and evaluation of efficacy and mechanisms of action in animal model of autoimmunity
... weight of 807.5 or two molecules with a weight of 270 and 537.5 H-NMR spectrum of CMX-13-5 was shown to resemble the 1H- NMR spectra of a bicyclic hexapeptide isolated by the group of Itokawa and ... increased with the age of the mice, with the majority of the untreated and DMSO control mice dying of renal failure at 16-24 weeks of age Treatment of the MRL-lpr/lpr mice with CMX-13 and dexamethasone ... express my sincere gratitude and appreciation to my supervisors Professor Yap Hui Kim and Associate Professor Ang Siau Gek, from the Department Paediatrics and the Faculty of Chemistry, respectively,...
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báo cáo hóa học:" Efficacy, Safety and Pharmacokinetics of Once-Daily Saquinavir Soft-Gelatin Capsule/Ritonavir in Antiretroviral-Naive, HIV-Infected Patients" pot
... at least dose of study medication and had at least postbaseline safety assessment Efficacy and Safety Measures The primary efficacy variable was the proportion of patients with plasma HIV-RNA values ... population consisted of 110 patients: 52 and 58 patients in the saquinavir-SGC/ritonavir and efavirenz arms, respectively The safety population consisted of 161 randomized patients: 81 and 80 patients ... once daily in in the safety population of patients treated with either saquinavir-soft gelatin Figure Mean levels of triglycerides and total cholesterol in the safety population of patients treated...
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Báo cáo y học: "Efficacy and safety of aripiprazole in the treatment of bipolar disorder: a systematic review" pdf
... Hypnotics and sedatives were used by 25% of aripiprazole patients and 21% of placebo patients At least adverse event was reported by 142 (76%) of the 186 patients in the placebo group and 154 (87%) of ... validity of psychiatric diagnosis perplexes the problem and makes the gathering of scientific data difficult, because the diagnosis of BD in particular is often made retrospectively and carries ... the role of the 5-HT-mediated systems in the mechanism of action of aripiprazole [33] Aripiprazole reaches peak concentration (Cmax) to h after ingestion, and has a bioavailability of 87% and half...
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Báo cáo khoa học: "Radiosurgery for pituitary adenomas: evaluation of its efficacy and safety" ppsx
... actuarial rate of HC and HN were 62,4% and 37,6%, respectively, and the 5-year actuarial rate were 81,2% and 55,4%, respectively (Figures and 2) Table Distribution of results of radiological ... pre and post-radiosurgical GH and IGF-1 levels were, respectively, 5.8 and 2.9 ng/ml and 688.5 and 361.5 ng/ ml; the median pre- and post-radiosurgircal prolactin levels were, respectively, 55 and ... the effects of Gamma Knife RS on the growth and endocrinological response and its safety in the treatment of pituitary adenomas Materials and methods Patient population Forty-two out of the first...
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Báo cáo y học: "A double blind, randomized, placebo controlled study of the efficacy and safety of 5-Loxin® for treatment of osteoarthritis of the knee" potx
... double-blind and placebo-controlled clinical study, we sought to evaluate the efficacy and safety of 5-Loxin® in treatment of OA of the knee We assessed the effectiveness of 100 mg/day and 250 mg/ ... Haematological and biochemical evaluations For assessment of safety of 5-Loxin®, several parameters were evaluated in serum, urine and whole blood of all patients at each visit of the study duration ... analyses using SAS software to evaluate the efficacy of two doses of 5-Loxin® in comparison with the placebo group in terms of improvement in pain and physical ability scores, and to assess biomolecular...
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Báo cáo y học: " Efficacy, safety and pharmacokinetic of once-daily boosted saquinavir (1500/100 mg) together with 2 nucleos(t)ide reverse transcriptase inhibitors in real life: a multicentre prospective study" ppt
... the efficacy raised to 90.4%, with similar results regardless of baseline VL and CD4 counts The presence of more adherent patients in the “simplification” group may be the cause of the higher efficacy ... open-label characteristics of the study, the heterogeneity of the analyzed population and the lack of available genotypic resistance tests in some of the patients at baseline and after virological ... under 100 ng/ml, and of them had a satisfactory virological response No correlations were found between SQV levels and either weight, gender or the presence of chronic hepatitis and/ or cirrhosis...
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Báo cáo y học: "Safety, immunogenicity and preliminary efficacy of multiple-site vaccination with an Epidermal Growth Factor (EGF) based cancer vaccine in advanced non small cell lung cancer (NSCLC) patients" pdf
... currently ongoing and it is primarily intended to evaluate the efficacy of CimaVaxEGF vs best supportive care in terms of survival In this manuscript, we make a comparison of the impact of using high ... cells (WBC) count of at least 3, 000/μL, platelet count of at least 100, 000 μL, hemoglobin of at least 10 g/dl, life expectancy of at least months, and creatinine, bilirubin, and transaminase ... studies were compared to assess the impact of high dose vaccination at multiple anatomic sites in terms of immunogenicity, safety and preliminary efficacy of CimaVax-EGF in advanced NSCLC patients...
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Báo cáo y học: " Phytol-based novel adjuvants in vaccine formulation: 1. assessment of safety and efficacy during stimulation of humoral and cell-mediated immune responses" doc
... potential of both phytol and PHIS-01 to that of some commonly used adjuvants (Complete and incomplete Freund's adjuvants, TiterMax, Ribi's adjuvant system, and Alhydrogel) Since phytol and PHIS-01 ... Effects of PHIS-01 and other adjuvants on induction of IgG subclasses The effectiveness of a vaccine formulation depends to a large extent on the type of antibody subclasses induced, and adjuvants ... Induction of anti-tumor effector T cells Since induction of cytolytic effector cells is pivotal in ensuring the success of tumor vaccines, we investigated relative efficacy of phytols and known...
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Báo cáo y học: " Impact of race on efficacy and safety during treatment with olanzapine in schizophrenia, schizophreniform or schizoaffective disorde" pdf
... all-cause time to discontinuation and PANSS Total score between white, black, and Hispanic subgroups Another study looked at the impact of race on the efficacy and safety of long-acting risperidone ... Ciliberto N, Bossie CA, Urioste R, Lasser RA: Lack of impact of race on the efficacy and safety of long-acting risperidone versus placebo in patients Page 11 of 11 27 28 29 30 31 32 33 34 35 36 37 38 ... protocol and baseline value and using the method of last observation carried forward (LOCF) Patients with a baseline and at least one post-baseline measure were included in all efficacy and laboratory...
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Báo cáo y học: " Efficacy, safety and tolerability of escitalopram in doses up to 50 mg in Major Depressive Disorder (MDD): an open-label, pilot study" doc
... associated higher rates of discontinuation due to intolerance The objectives of this open-label, pilot study were to investigate the efficacy, safety and tolerability of escitalopram in doses ... Improvement of Illness (CGI-I) scale [11] Outcome measures: Safety and tolerability Safety and tolerability outcomes were assessed from adverse events (AEs), vital signs, weight, physical examination and ... relationship between age group, gender and history of anxiety and the probability of achieving remission at the end of the study A repeated measures analysis of covariance (ANCOVA) was carried out...
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Báo cáo y học: " Efficacy and safety of an antiviral Iota-Carrageenan nasal spray: a randomized, double-blind, placebo-controlled exploratory study in volunteers with early symptoms of the common cold" doc
... Analysis of days of onset of common cold symptoms Shown are the numbers of patients for verum, placebo and total divided into groups with days of onset of common cold symptoms at the point of inclusion ... clear, colourless, odourless and free of particles Verum and placebo nasal sprays were identical in shape, size and colour to allow a double-blind design, and were randomized at the CRO Before ... patient 23 reported migraine and puffy eye lids, used ibuprofen and anti-histamine as concomitant medication and was therefore excluded from the efficacy analysis of symptoms One Iota-Carrageenan...
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Báo cáo y học: " Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease" potx
... (breathlessness on a scale of to 4; cough, sputum production and wheezing on a scale of to 3), use of daily rescue medication and concomitant medication were recorded in the patient’s diary and reviewed by ... in favour of aclidinium for cough and sputum production (Week 1), breathlessness (Week 12), wheezing (Week 28) and use of daily rescue medication (Weeks 12 and 28) (p < 0.05 for all) Safety The ... Pneumology and Thoracic Surgery, Grosshansdorf, Germany 6Department of Oncology, Haematology and Respiratory Diseases, University of Modena and Reggio Emilia, Modena, Italy 7Division of Pulmonary...
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Báo cáo y học: "Efficacy and safety of tiotropium in COPD patients in primary care – the SPiRiva Usual CarE (SPRUCE) study" ppsx
... (maximum change of 57.0 mm) and 3.5 mm (-1.0, 20.0) with placebo (maximum change of 61.0 mm) Safety Adverse events were reported in 51.0% of patients treated with tiotropium, and 61.5% of patients ... all tiotropium studies [11-14] and supports the clinical relevance of the sustained efficacy of tiotropium and reduction of COPD exacerbations The actual magnitude of the reduction in rescue medication ... Pedersen OF, Peslin R, Yernault JC: Lung volumes and forced ventilatory flows Work Group on Standardization of Respiratory Function Tests European Community for Coal and Steel Official position of...
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