role of lifestyle factors in bone health
Báo cáo khoa học: Alternative initiation of transcription of the humanpresenilin 1gene in SH-SY5Y and SK-N-SH cells The role of Ets factors in the regulation ofpresenilin 1 pptx
... recognize specifically Ets motifs flanking the +1 site (A) The binding of nuclear factors is eliminated by mutations in Ets motifs The binding of nuclear factors present in SK-N-SH (K) or SH-SY5Y (H) ... sequences flanking the Ets motif determine activity through protein–protein interactions between Ets factors and factors binding at adjacent sites, as well as cofactors that not bind DNA themselves ... contains two DNA binding inhibitory domains flanking the Ets domain: the central 87 amino acid inhibitory domain is poorly conserved and virtually specific to ERM, and the C-terminal domain that...
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Báo cáo y học: "Efficacy of lifestyle interventions in physical health management of patients with severe mental illness" doc
... superior to lifestyle intervention plus placebo in decreasing insulin and Insulin Resistance Index (IRI), while metformin alone has the same effect on insulin sensitivity as lifestyle intervention ... of smoking cessation interventions The effectiveness of lifestyle interventions in smoking cessation consisting of counseling is established, and the addition of a pharmacological treatment increases ... changes in risk of CVD [95] Smoking cessation The effectiveness of lifestyle intervention in smoking cessation has been studied when the intervention consists only of lifestyle counseling and...
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Báo cáo y học: "The role of cyclooxygenase-2 in bone repair" doc
... selectivity of this group of compounds might allow inflammation to be inhibited with minimal effects on certain homeostatic mechanisms, their role in bone metabolism and repair remains unclear Review of ... Cyclo-oxygenase-2 function is essential for bone fracture healing J Bone Miner Res 2002, 17:963-976 Einhorn TA Do inhibitors of cyclooxygenase-2 impair bone healing? J Bone Miner Res 2002, 17:977-978 Zhang ... controlled trials in patients In the absence of these kinds of prospective study, it is tempting to translate animal data to our management of patients However, before doing this, certain points must...
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Báo cáo y học: " The role of angiogenic factors in predicting clinical outcome in severe bacterial infection in Malawian children" doc
... maintenance of vessel integrity Angiopoietin-1 (Ang-1) and Ang-2 are ligands of the endothelial receptor tyrosine kinase Tie-2, which is a key regulator of endothelial function [14] Binding of circulating ... outcome in children with severe bacterial infection, the association being independent of confounding factors in the case of Ang-1 High Ang-2 concentrations are associated with mortality In bacterial ... following definitions: Cases (n = 293): Children first seen with signs and symptoms of bacterial meningitis or pneumonia in whom growth factors were determined Healthy controls (n = 15): Healthy...
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báo cáo sinh học:" Wrong schools or wrong students? The potential role of medical education in regional imbalances of the health workforce in the United Republic of Tanzania" potx
... parents living in a rural area, motivation by an interest in medicine, intended specialization in medicine, intended specialization in public health, community service during studies, and having done ... with specialist training in family or rural medicine Rural practice during the training Most students had some exposure to rural areas during medical training as shown in Row of Table The few (20% ... having a rural background [24] The influence of training institutions In a survey of 189 medical students at Monash University in Australia, Somers (2000) finds that the intention to practice in...
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báo cáo khoa học: " Role of "external facilitation" in implementation of research findings: a qualitative evaluation of facilitation experiences in the Veterans Health Administration" potx
... step of the analysis, including the summary of the cross-case synthesis Findings Study findings are presented in terms of key issues that emerged relative to the evaluative questions In reading ... provision of needed resources, verbal reinforcement of the importance of the initiative, and integration of changes into routine QI structures Conversely, lack of support was noted in, e.g., a lack of ... Implementation of research findings into practice is a complex undertaking that has often fallen short of expectations In part, this is due to the current lack of substantive knowledge regarding both individual...
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ROLE OF THE ERP29 IN MIGRATION, APOPTOSIS AND PROLIFERATION IN BONE MARROW STEM CELLS
... cells by interacting with actin filaments in migrating cells Integrins can also act as signal transducer in the “inside-out signaling” model The activation of integrins is caused by talin binding ... as profiling and ADF/cofilin, are also act as regulators in mediating actin polymerization by controling the availability of activated actin monomers, debranching and depolymerizing proteins and ... group box HSP27 Heat shock protein 27 IAP Inhibitor of apoptosis protein IFN-γ Interferon-γ IL-10 Interleukin-10 IRE1α Inositol-requiring 1α JUN JUN N-terminal kinase Lgl Lethal giant larvae LPA...
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Báo cáo y học: "Functional genomics analysis of low concentration of ethanol in human hepatocellular carcinoma (HepG2) cells. Role of genes involved in transcriptional and translational processes"
... ethanol-induced mucosal injury in the upper gastrointestinal tract leading to increase in the permeability of the gut mucosa to endotoxins [43, 44] These factors are involved in ethanol-induced ... NM_014393 ▲ 1.52 regulation of transcription protein binding double-stranded RNA binding DNA binding ▼ 5.02 protein binding NM_001149 NM_004242 ▲- increased ▼- decreased Validation of microarray results ... ANK3 Gene title cofactor of BRCA1 integrin, beta staufen, RNA binding protein, homolog (Drosophila) high mobility group nucleosomal binding domain ankyrin 3, node of Ranvier (ankyrin G) Signal Log...
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The role of leadership theory in raising the profile of women in management
... viewed as limited in raising the profile of women in management However, during this period of research, there was an emerging recognition of the importance of a concern for people in the behavioural ... more typical of male behaviours Of interest is the inclusion of ‘‘control’’ as a significant feature of the transactional style, common in definition of leadership in the 1990s In contrast, women ... superiority in utilising effective leadership styles of interaction with their subordinates and organisational outcomes, actually translates into a dramatic increase in the numbers of women being appointed...
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Globalization: the Role of Institution Building in the Financial Sector _ The Case Study of China
... The role of FDI in institution building Over the past 20 years, foreign financial institutions, mainly foreign banks have played an important role in the opening up of Chinese financial industry ... technology, in exploring on-line banking business as well as in promoting non-bank financial institutions Efforts should be made in upgrading financial operations and financial services, and in conducting ... China Statistics Yearbook, China Financial Yearbook and People’s Bank of China Statistics Quarterly bulletin B Development of direct financing and indirect financing markets providing financing...
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Tài liệu Báo cáo khoa học: Role of Kupffer cells in pathogenesis of sepsis-induced drug metabolizing dysfunction pptx
... shown that interactions between KCs and endotoxin comprise the initiating event leading to hepatotoxicity in liver injury, including endotoxemia and ischemia ⁄ reperfusion injury [14] In our studies, ... receptor signaling is independent of Toll-interleukin receptor domain-containing adaptor protein Drug Metab Dispos 36, 95–101 10 Ghose R, Guo T & Haque N (2009) Regulation of gene expression of hepatic ... performed in accordance with the guidelines of the National Institutes of Health Treatment with GdCl3 and experimental groups For depletion of KCs in vivo, 7.5 mgÆkg)1 of GdCl3 was injected via...
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Tài liệu The Role of BCG Vaccine in the Prevention and Control of Tuberculosis in the United States: A Joint Statement by the Advisory Council for the Elimination of Tuberculosis and the Advisory Committee on Immunization Practices docx
... boosted by administering a tuberculin skin test week to year after the initial postvaccination skin test; ongoing periodic skin testing also might prolong reactivity to tuberculin in vaccinated persons ... preventing pulmonary TB in adolescents and adults These studies also were not useful in determining a) the efficacy of BCG vaccine in HCWs or b) the effects on efficacy of the vaccine strain administered ... Tuberculin Skin Testing and Interpretation of Results After BCG Vaccination Postvaccination BCG-induced tuberculin reactivity ranges from no induration to an induration of 19 mm at the skin-test site...
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Tài liệu Rethinking the Role of the State in Finance doc
... Rethinking the Role of the State in Finance Global Financial Development Report 2013 Rethinking the Role of the State in Finance Washington, D.C © 2012 International Bank for ... important role, especially in providing supervision, ensuring healthy competition, and strengthening financial infrastructure Incentives are crucial in the financial sector The main challenge of financial ... possible countercyclical role of state-owned financial institutions, and the role of the state in promoting information sharing—all topics that are examined in the current Global Financial Development...
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Tài liệu The Role of Community Banks in the U.S. Economy pdf
... them to maintain higher net interest margins Indeed, during most of the 1990s, the net interest margin of small banks held steady at over 4.5 percent, while the net interest margin of large banks ... key role serving certain types of communities and providing certain types of banking services ECONOMIC REVIEW • SECOND QUARTER 2003 17 Definition of a community bank There is no single definition ... Banking Industry,” Journal of Banking and Finance, August Sullivan, Richard J 2000 “How Has the Adoption of Internet Banking Affected Performance and Risk in Banks? A Look at Internet Banking in...
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Tài liệu SICK WATER? THE CENTRAL ROLE OF WASTEWATER MANAGEMENT IN SUSTAINABLE DEVELOPMENT pdf
... Depending on the type of ore deposit being mined, tailings can also contain heavy metals like copper, lead, zinc, mercury and arsenic The contaminants in mine waste may be Cooling waters used in industrial ... Figure 19 in the timing and intensity of rainfall, or the period of time without rain, as well as affecting the quality of water in rivers and lakes through changes in the timing and volume of peak ... Before Mining Rainfall filtering through soil Surface runoff Sulfide Filtering soils Groundwater After Mining The problem of poor water quality in many urban centres has been one of the factors...
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Tài liệu Báo cáo khoa học: A role of miR-27 in the regulation of adipogenesis ppt
... or without hematoxylin staining In hypoxia experiments, 3T3-L1 cells were maintained in a hypoxia chamber (Invivo 400; Ruskinn Inc., Cincinnati, OH, USA) constantly maintained at 1% O2 Culture ... initiated at 48 h post-transfection by maintaining the cells in culture medium containing 2% horse serum Cells were fixed on day of differentiation and stained with hematoxylin and eosin One of ... DMEM containing 10% fetal bovine serum OP9 cells were grown in aMEM containing 20% fetal bovine serum C2C12 cells were maintained in DMEM containing 10% fetal bovine serum Adipogenic differentiation...
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Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Potential role of ceramide metabolism in Lewy body disease pptx
... phospholipase A2 participates in ER stress-induced INS-1 insulinoma cell apoptosis by promoting ceramide generation via hydrolysis of sphingomyelins by neutral sphingomyelinase Biochemistry 46, 10170– ... should have a key role in our understanding of the mechanisms of the disease We propose that pathology data will, in most cases, be more insightful than clinical data in defining the disease This ... transport of cholesterol to post-lysosomal destinations Cells from NPC subjects show a decrease in acid sphingomyelinase activity, leading to the accumulation of sphingomyelin [27] Because one of the...
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Tài liệu Báo cáo khoa học: Role of ceramide kinase in peroxisome proliferatoractivated receptor beta-induced cell survival of mouse keratinocytes ppt
... 3821 Role of CerK in PPARb-induced keratinocyte survival K Tsuji et al Fig Schematic model illustrating the role of CerK in cell survival mediated by PPARb in mouse keratinocytes Under injury ... keratinocytes [14] 3816 In this study, we examined the interaction between CerK and PPARb, and its role in regulating keratinocyte survival We report that in a mouse keratinocyte cell line upregulation ... important role in keratinocyte survival during skin wound healing, and PPARb expression is elevated at injury sites [10,15] We investigated whether skin barrier disruption by tape-stripping would induce...
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Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: role of environmental factors pdf
... ability of B19 to induce certain properties in normal human synovial fibroblasts [5] These investigators observed that incubation with B19-containing serum induces an invasive phenotype in normal ... activity of the VP1 protein unique region being prerequisite for this process [6] Infection of the macrophage cell line U937 or bone marrow cells with B19 has been shown to induce the expression of interleukin ... pain in RA patients [54] Verges et al suggested that some meteorological variables affect the occurrence of pain in RA and that low temperature increases the risk of joint pain [55] Concluding...
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Tài liệu Báo cáo khoa học: Molecular aspects of rheumatoid arthritis: role of transcription factors ppt
... their synthesis or activity, including the inhibition of protein–protein interactions in the activating signaling cascade of the transcription factor of interest Specific inhibitors have already been ... upregulation of MMPs in the RA synovium correlates with increased DNA-binding activity of AP-1 and increased expression of Fos ⁄ Jun [30] Thus, AP-1 proteins have significant pathological roles in RA ... [32–35] Concluding remarks Transcription factors play critical roles in the function of immune effector cells, including cytokine ⁄ chemokine expression and also in the control of synovial cell...
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Tìm thêm: khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25