role of glial cells

... Journal compilation ª 2011 FEBS Role of Kupffer cells in pathogenesis of sepsis-induced drug metabolizing dysfunction Tae-Hoon Kim*, Sang-Ho Lee* and Sun-Mee Lee School of Pharmacy, Sungkyunkwan University, ... study aimed to determine the role of Kupffer cells (KCs) in cytochrome P450 (CYP) isozyme activity and the expression of its gene during polymicrobial sepsis. For ablation of KCs, rats were pretreated ... the inhibition of CYP activity observed in the absence of changes in protein expression in rabbit he- patocytes [22]. ROS indirectly reduced the activity of selected isoforms of CYP by inducing...

Ngày tải lên: 14/02/2014, 18:20

Ngày tải lên: 20/06/2014, 01:20

Ngày tải lên: 19/06/2014, 22:20

... expression of transcription factors with subsequent regulation of apoptotic genes in human hepatocellular carcinoma (HCC) HepG2 cells. However, the role of ethanol on the expression of genes ... matrix-receptor interaction and regulation of cytoskeleton. These data suggest an important role of integrin in the molecular mechanisms of ethanol effects in HepG2 cells. The other ethanol-regulated ... concentrations of 1x10 5 /ml. Six sets of experiments were performed. Each set consist of two groups as follow: group 1, HepG2 treated cells with 1 mM ethanol for 6 h; and group 2, HepG2 cells without...

Ngày tải lên: 31/10/2012, 15:28

... phosphorylation of GRK2 and PKCα; with values of 109% and 104%, respectively, combined with dephosphorylation of ROKα, PKCδ and PKCμ; with values of -56%, -44% and -28% of control cells, respectively. ... control cells at 2 h (* p < 0.05), 4 h († p < 0.05), and 6 h (# p < 0.05). Ethanol regulates the expression of genes of the Fas signaling cascade To further investigate the role of ... respectively. These data confirm the role of G-protein coupled receptors as a regulatory mechanism of ethanol-induced apoptosis. Figure 1 Effect of inhibitors of G-protein coupled receptors (GPCR)...

Ngày tải lên: 31/10/2012, 15:37

... (\P < 0.01) and TG-stimulated cells (\\P < 0.001). Fig. 3. Effects of TG on the induction of mRNA of different phospho- lipase A 2 isoforms in Jurkat T -cells. Cells were treated for two hours with ... to ascertain the role of PLA 2 activation and hence released AA in the capacit- ative influx of calcium in Jurkat T -cells. These cells represent a good model to study the effects of AA per se as ... isotype of PLA 2 is phospho- rylated after anti-CD3 stimulation in human T-lympho- cytes. Addition of TG potentiates the induction of mRNA of these four PLA 2 isotypes. The mechanism of action of TG...

Ngày tải lên: 08/03/2014, 09:20

... is likely that Ets elements play a major role in determining both the level of expression and the location of the start of transcription of PS1 . In the Ets family of transcription AB Fig. 6. ERM and ... transcription of the human presenilin 1 gene in SH-SY5Y and SK-N-SH cells The role of Ets factors in the regulation of presenilin 1 Martine Pastorcic 1 and Hriday K. Das 1,2,3 1 Department of Pharmacology ... ronal cells [26,27]. The specificity of Ets elements is specified by four factors: their site of synthesis and chemical modification, the presence of specific Ets promoter motifs and the set of nuclear...

Ngày tải lên: 16/03/2014, 18:20

Ngày tải lên: 23/03/2014, 10:21

Ngày tải lên: 30/03/2014, 04:20

Ngày tải lên: 18/06/2014, 16:20

Ngày tải lên: 19/06/2014, 08:20

Ngày tải lên: 20/06/2014, 04:20

Ngày tải lên: 20/06/2014, 07:20

... Overbearing  Show humility not arrogance  Enhance the “face” of your counterpart • “Now I see where you’re going with that  idea…It’s a good one” • “I hadn’t thought of it that way” • “You’re a step ahead of me on this one” • “That’s more in your area of expertise than  mine, so I’d like to hear more” The Role of Power Chapter 8 Outline  Role of Power  Rules for Using Power Rule #4: Don’t ... Stuff  Don’t push too hard for minor gains  Quibbling over small stuff creates bad  will  Bundle small items with others into one  package • Example – Negotiating relocation  expenses as part of a salary negotiation Rule #16: Find the Soft Spot  Encourage others to open up • Gain disclosure of something private or  personal about your counterpart • Expression of trust  Identify true motivations and sources  of objections  Be patient and use probing questions  Attempt to satisfy some need ... Answers  Don’t flaunt your expertise  Help the other side remain confident (face  issues)  Utilize esteem­reviving comments • Useful when other side takes offense or  negatively reacts to statements • “If you don’t mind, let’s back up here to see if I’ve  misstated my intentions.” • “If I seemed to be abrasive a few moments ago…” • “I may have spoken too quickly” Role of Power  Power defined:  • Ability or official capacity to exercise control;  authority • Ability to influence or control others  Sources of Power • Information • Status • Social networks • Physical appearance ...

Ngày tải lên: 22/08/2012, 22:07

... efficiently, the reputational capital of an agent must equal the present value of the stream of future profits, or franchise value, of her business. The concept of reputational capital is meaningful ... The Journal of International Trade and Economic Development, December, 261-81. OECD, 1993, The Role of Financial Institutions in the Transition to a Market Economy , Study of the Group of Financial ... Structural implications of CTF Circuit theory of finance (CTF) bears important implications in terms of financial market structure, microeconomic imbalances, and the role of saving for economic...

Ngày tải lên: 24/10/2012, 09:33

... Hanoi University of Foreign Trade Faculty of Business English 2.3. Functions & Main Activities of VIFFAS VIFFAS has the function of socio-professional associated organization of the enterprises, ... professional colleagues on the world. The Association has the role of coordinating the activities of the members in order to protect the interests of the members and improve the position of ... University of Foreign Trade Faculty of Business English 2.4. Role of VIFFAS to Vietnam Freight forwarding industry in international economic integration process 2.4.1. Achievements of VIFFAS Evaluating...

Ngày tải lên: 27/10/2012, 16:42

... concentrations of isoflavones. The amount of isoflavones in soybeans varies depending upon the type of soybean, geographic area of cultiva- tion, and harvest years of soybeans [33-36]. In addition, isoflavone ... transfer of fatty acids to extra adipose tissues. Another possible mechanism of action of soy protein is via stimulation of adiponectin, a cytokine produced by fat cells that plays a key role ... alone or soy protein hy- drolysate [76]. Part of the antiobesity effect of soy protein may be due to the presence of the isoflavones, since soy isoflavones have been shown to decrease fat accumu- lation...

Ngày tải lên: 31/10/2012, 14:59

... Communication Human toxoplasmosis and the role of veterinary clinicians Laura Kramer Department of Animal Health- Veterinary Parasitology Laboratory- University of Parma,Parma (Italy) Published: ... toxoplasmosis is one of the most com- mon parasitic zoonoses worldwide. As for other zoonoses, veterinarians play an important role in the education of the human population regarding the risk of infection. ... animals, pets, etc). Toxoplasmosis represents one of the more diffi- cult “educational” challenges for small animal clini- cians. Veterinarians are often faced with the need to explain to their...

Ngày tải lên: 03/11/2012, 11:06

... amount of income is essential for people to afford basic needs. This type of poverty focuses on material aspects of poverty such as income below the poverty datum line, unemployment and lack of ... order to improve the quality of life of the poor and rural people adult education programs should include as one of its components the observation and imitation of the artisans and other skilled ... perspective or needs of people from below. At least one language of high status is used to exclude speakers of low status languages. Marginalized groups are always at the disadvantage of the culture...

Ngày tải lên: 05/11/2012, 16:27

... month, profit of transactions was nearly VND 7 billion, balance of call deposit account was VND 1,425 million. Collected service fee of the last quarter of the year was zero because of free issuing ... VND million. As can be seen in the table, the total profit of services had steadily increased in all period. In particular, the total profit of November and December went up sharply, at 35,3% ... contributed directly to big accumulation of 12 months. The growth of total profit showed that the Department has continuously made an effort to diversify the variety of services to meet and satisfy...

Ngày tải lên: 03/04/2013, 12:13