... sister She never behaves with respect to the other Just because she is her sister – except perhaps in those cases when her mother says, “Give in to her.” Inthe game of sisters playing at “sisters,” ... are sisters: they are dressed alike, they walk about holding hands – in short, they enact whatever emphasizes their relationship as sisters visa-vis adults and strangers The elder, holding the ... the other sister inthe whole play situation.) Only actions that fit these rules are acceptable inthe play situation Inthe game a situation is chosen that stresses the fact that these girls...
... N-terminal cysteine residues inthe subunit of VnfA bind the single Fe -S cluster A possible scenario is that two of three cysteine residues (Cys15 and Cys8 or Cys10) bind the Fe -S cluster and the ... same Fe -S cluster because the amino acid sequence, Cys8Glu9Cys10, restricts the cysteine residues from binding to the same cluster Discussion Prosthetic group of VnfA The EPR data ofthe whole ... number of subunits inthe native form and the type and presumable locus ofthe Fe -S cluster, as well as the stoichiometry ofthe cluster Activity assays conducted in vivo allow discussion of a role...
... Cancer Research Center, Seattle, WA98109, USA 4Division of Oncology, Department of Medicine, University of Washington, Seattle, WA98195, USA Authors’ contributions Both authors express in this letter ... envision a similar potential for RIT given in advanced disease either alone or combined with chemotherapy, as initial treatment or in relapse [2,3,5] The 10-year progression-free survival as observed ... details Department of Nuclear Medicine, University Hospital of Lausanne, Lausanne, Switzerland 2Department of Nuclear Medicine, University Hospitals of Geneva, Geneva, Switzerland 3Fred Hutchinson...
... and RIS, respectively) Robustness and sensitivity analysis In order to assess the robustness and sensitivity ofthe current findings we (a) pursued an Intent-to-Treat (ITT) analysis for the adherent ... treatments currently provided to schizophrenia patients in usual care settings The six participating sites represented large systems of care inthe U .S including university health care systems, community ... across treatment sites, type of insurance coverage, DSM-IV diagnostic subtypes, and lifetime episodes of schizophrenia, defined as a period of time in which the patient had worsening of symptoms...
... node sampling In this case, the surgical approach was not radical in intent because the uterine neoplasia was an incidental finding Therefore, the lymph node status was not known In this setting, ... that, in case of a relapse and need for new chemotherapy regimens, maintaining as much functioning marrow as possible presents another advantage of using IMRT Roeske and cols have shown the main ... This study did not evaluate specifically serous papiliferous tumors, but this subset of tumors is known to have a worse prognosis This patient is classified as having a high risk tumor It is considered...
... approval ofthe final manuscript SY, ML, DD, and GB co-supervised the project, assisted inthe interpretation ofthe statistical analysis, and assisted inthe preparation and approval ofthe manuscript ... lies inthe dose to the pelvic soft tissues that lie between the expanded nodal target volume and the organs at risk Conformal pelvic vessel targeting does not specifically address these tissues ... toxicity This potential cost to the normal tissues is necessary to deliver the dose described to the rest ofthe pelvis The clinical impact of this difference in terms of acute and late effects is currently...
... down-regulated probe sets (n= 204), regardless of their fold-change status at the total RNA level The content of these two lists of genes were separately analyzed using the Ingenuity Systems Pathways Knowledge ... revealed the involvement of lesser known nuclear proteins inthe hepatocytic biology, such as SMARC, MEF and EGR1 proteins, and novel associations, such as theroleof several IFN-associated or induced ... proteins inthe acquisition ofthe hepatocytic phenotype STAT1 is one ofthe key elements for the induction ofthe type I IFN response Its up-regulation, as well as the up-regulation of several other...
... the business process of an organization According to [12], it can show the structure ofthe business process” which is lost when using “current process modeling” This is one ofthe reasons why ... processes ofthe organization while RAD technique links these business processes to the software development concepts (requirements, use case) Besides, using this framework, the business processes can ... inthe IAM, the PM shows the casual and conditional relationships between different steps ofthe related transactions Capturing the business processes ofthe organization, it can be used as the...
... same in kind as those associated with the introduction of unmodified organisms and organisms modified by other methods UK s House of Lords Statement on Safety The UK s House of Lords Select Committee ... This white paper has had significant impact inthe U .S and other countries Its most significant conclusions include: (1) There is no evidence ofthe existence of unique hazards, either inthe use ... products; it is considered by the experts as sufficient to assess the safety of present GM products.”27 Biotechnology Provides Nutritional Benefits Since the early efforts of biotechnology, scientists...
... interfragmentary screw fixation of single fragments may in single cases be necessary [Figure 10] Insertion ofthe remaining shaft screws into the ulna completed the stable osteoynthesis [Figure 11] ... was not advisable to utilize fixed angle screws inthe ulna shaft prior to inserting the “home run” screw since the screws that are used to stabilize the plate to the ulna shaft may impair insertion ... figure -of- eight tension band wire fixation were used in many cases resulting in a high rate of revision surgery Hypothesis of this study was that the intermediate fragment plays a key role for...
... interfragmentary screw fixation of single fragments may in single cases be necessary [Figure 10] Insertion ofthe remaining shaft screws into the ulna completed the stable osteoynthesis [Figure 11] ... was not advisable to utilize fixed angle screws inthe ulna shaft prior to inserting the “home run” screw since the screws that are used to stabilize the plate to the ulna shaft may impair insertion ... figure -of- eight tension band wire fixation were used in many cases resulting in a high rate of revision surgery Hypothesis of this study was that the intermediate fragment plays a key role for...
... Anesthesiology (ASA) classes assessed surgical risk; cases were included in ASA class IV Group V patients were considered unfit to general anesthesia at the anesthesiologist evaluation Patients ... that included a vaginal margin being at least 1,5 and maximum cm Anesthesiologists always performed a spinal anesthesia Group A was treated with abdominal hysterectomy with the same vaginal margin ... vaginal surgery appears safer Nevertheless, it does not allow exploration of peritoneal contents Therefore, an assessment of lymph nodal status is unachievable Moscarini et al World Journal of...
... mild asthma resulted in a significant increase in airway hyperresponsiveness that was associated with the elevation of sputum eosinophil numbers [17] A variety of findings suggest that atopic individuals ... on these cells T cells from asthmatic lungs show defective expression of Fas Co-culturing of T cells with IL-4 downregulates Fas expression on the cell surface The expression of IL-4 inthe asthmatic ... the secondary lack of Fas expression might explain the persistence of inflammatory cellular infiltrates in allergic asthma Apoptosis of TH2 lymphocytes (and possibly eosinophils) could represent...
... bleeding principally from NVUGB - the usual setting as this group comprises 80% to 90% of all bleeders seen [28] Because of their effect on decreasing portal pressure, somatostatin and analogues ... endoscopy with possible banding The mainstay of diagnosis and mortality-improving treatment for patients with peptic ulcers at high risk of rebleeding remains early endoscopy Competing interests ... stabilizes clot [11] and, possibly, accelerates healing of bleeding lesions over the 72 hours following endoscopic hemostasis [16,17] Somatostatin and octreotide inhibit acid, and decrease both pepsin...
... a set of successive steps towards the point The process of assimilating new information takes time Exploring issues in depth and detail rather than changing themes constantly allows people the ... Centres using simple, easy to use bilingual manuals and interactive sessions The training sessions were coordinated with the state to reinforce disease surveillance guidelines and outbreak response ... • involve users inthe planning and design ofthe system • build information cultures • strengthen capacity of users • set realistic goals • focus on the benefits ofthe system, rather than the...
... root surfaces ! Excessive pressure when brushing ! Use of stiff-bristled toothbrush ! Use soft-bristled toothbrush ! Avoid excessive pressure when brushing Congenital Anomalies ! Defects in newborns ... years of age should not routinely use fluoride rinses since they often swallow a significant amount ofthe rinse that can cause fluorosis or mottling ofthe permanent teeth Dental Sealants: Dental ... emphasize how important it is for their health development into adulthood ASK ADVISE ASSIST ARRANGE Χ If the answer is yes: the student to stop by discussing the risks, the health impacts and the...
... after the successful conclusion of a first democratic election COPING WITH FAILED STATES During the early 199 0s, the United Nations enjoyed a series of successes This winning streak and a consequent ... terms This reflects the greater access ofthe United States to donor assistance funds, including its own, and those ofthe international financial institutions to which it belongs In effect, the ... are employed and on the susceptibility ofthe society in question to the changes being fostered Nevertheless, success is also in some measure dependent on the quantity of international military...
... lane 4), therefore confirming the interaction of these two proteins previously observed biochemically [37] or using a yeast two-hybrid assay [39] Interestingly, inthe M2H system, the interaction ... Movies are presented at ten frames per second, representing a speed increase of ·40 Statistical analysis was performed using the graphpad prism, version (GraphPad Software, Inc., San Diego, CA, USA) ... with GRASP55 We next sought to define the nature ofthe GRASP55 binding site inthe MT1-MMP ICD pACT plasmids driving the expression of MT1-MMP ICDs containing single-, double- and triple-point mutations...