peripheral muscle dysfunction in chronic obstructive pulmonary disease
Báo cáo y học: " Skeletal muscle dysfunction in chronic obstructive pulmonary disease" pps
... changes include an increase in mitochondrial number, increased muscle capillarization, and an increase in muscle oxidative enzyme activity After intense training the proportion of type I fibers increases, ... successful in increasing lean body mass in patients with COPD In one study [67] an increase in the creatine phosphate/ creatine phosphate + creatine ratio (measured from quadriceps muscle biopsy) ... Deconditioning from disuse is believed to be a major contributing factor in the skeletal muscle dysfunction that is observed in patients with COPD Therefore, exercise training in this setting should...
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Báo cáo y học: " A prospective study of decline in fat free mass and skeletal muscle strength in chronic obstructive pulmonary disease" pot
... exacerbators Decline in QMVC in this cohort was not associated with disease severity, having frequent exacerbations or corticosteroid treatment Change in fat free mass during follow up Decline in FFM was ... difference in the results obtained In addition it was possible in most patients to correlate their reports of exacerbations with the medical notes relating to clinic attendances in the intervening year ... significantly greater decline in FFM in this group Maintenance therapy has been shown to attenuate the improvement in muscle bulk occurring with nutritional supplementation during pulmonary rehabilitation...
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Báo cáo y học: "Abdominal muscle fatigue following exercise in chronic obstructive pulmonary disease" docx
... in healthy individuals [18,19] In COPD, the abdominal muscles are frequently recruited even during resting breathing [20] When walking to exhaustion, inspiratory work of breathing in COPD rises ... case in normal subjects, in whom the distinction into inspiratory and expiratory is not absolute During exercise, at least in normal subjects, the expiratory muscles act as accessory muscles of inspiration ... resistant muscle fibres, or because muscle shortening due to lung hyperinflation protects against fatigue [42] Conversely abdominal muscles lengthen during hyperinflation potentially rendering them...
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báo cáo khoa học:" Predictors of health status do not change over three-year periods and exacerbation makes difference in Chronic Obstructive Pulmonary Disease" ppsx
... baseline (Baseline Dyspnea Index) in order to answer questions regarding the TDI [28] Therefore, we used the MMRC scale which is a traditional instrument included in the BODE index [20] In multiple ... follow-up This finding reinforces the impact of exacerbation in clinical outcomes; exacerbations of COPD indicate clinical instability and progression of the disease and are associated with increased ... (SGRQ) in patients with chronic obstructive disease in Brazil J Bras Pneumol 2000, 26: 119-125 17 Jones PW: Interpreting thresholds for a clinically significant change in health status in asthma...
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báo cáo khoa học:"Comparison of health-related quality of life measures in chronic obstructive pulmonary disease" potx
... Organization: Chronic obstructive pulmonary disease. [http:// www.who.int/mediacentre/factsheets/fs315/en/index.html], Accessed February 10, 2011 Global Initiative for Chronic Obstructive Lung Disease: ... less efficient at discriminating between COPD stages (RE < 1) (Table 2) For the purpose of discriminating among COPD patients according to stage of disease, results indicated that only the SGRQ ... in studies of other conditions [28-30] In peripheral arterial disease, the disease- specific Vascular Quality of Life (VascuQol) measure was more discriminative than the EQ-5D and SF-36 [28] In...
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Báo cáo y học: " Colour of sputum is a marker for bacterial colonisation in chronic obstructive pulmonary disease" pps
... concentrations of pro-inflammatory cytokines, including interleukin-1 (IL-1), interleukin-6 (IL-6), interleukin-8 (IL-8), and tumour necrosis factor-alpha (TNFalpha) were measured using quantitative ... Jansen HM, Lutter R: Persisting Haemophilus influenzae strains induce lower levels of interleukin-6 and interleukin-8 in H292 lung epithelial cells than nonpersisting strains Eur Respir J 1997, 10:2319-2326 ... determinants of exacerbation in chronic obstructive pulmonary disease Arch Intern Med 2005, 165:891-897 Miravitlles M: Exacerbations of chronic obstructive pulmonary disease: when are bacteria...
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Báo cáo y học: " Systemic inflammation in chronic obstructive pulmonary disease: a population-based study" ppt
... COPD stages [10] In contrast, an inverse association between higher levels of circulating inflammation-sensitive proteins, including CRP, interleukin (IL)-6 and alpha-1 antitrypsin (A1AT), and ... ageing rate and longevity FEBS Lett 2005, 579:2035-2039 Ben-Zaken Cohen S, Paré PD, Man SFP, Sin DD: The growing burden of chronic obstructive pulmonary disease and lung cancer in women Examining ... on systemic biomarkers of inflammation in chronic obstructive pulmonary disease Am J Respir Crit Care Med 2008, 177:1207-1214 Barnes PJ: Chronic obstructive pulmonary disease N Engl J Med 2000,...
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Báo cáo y học: " Efficacy and safety of once-daily aclidinium in chronic obstructive pulmonary disease" potx
... to inhaled corticosteroids prior to screening † Data missing for four patients in ACCLAIM/COPD I (two each in the aclidinium and placebo arms) BMI: body mass index; COPD: chronic obstructive pulmonary ... 350 400 COPD: chronic obstructive pulmonary disease Figure Kaplan-Meier survival curves for the time to first moderate or severe chronic obstructive pulmonary disease exacerbation in ACCLAIM/COPD ... Garcia GE, Ferrer P: Safety and pharmacokinetics of single doses of aclidinium bromide, a novel long-acting, inhaled antimuscarinic, in healthy subjects Int J Clin Pharmacol Ther 2009, 47:460-468 Chanez...
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Báo cáo y học: "Two-year home-based nocturnal noninvasive ventilation added to rehabilitation in chronic obstructive pulmonary disease patients: A randomized controlled trial" pot
... 30-minute periods of cycling exercises, walking, and inspiratory muscle training each The cycling protocol consisted of intervals of one minute loaded cycling (aimed at 140% of a patient’s initial ... and one minute unloaded cycling, during 30 minutes [14] Inspiratory muscle training was performed on an inspiratory threshold device at an interval basis (two minutes of loaded breathing, followed ... Global Initiative for Chronic Obstructive Lung Disease (GOLD) 2010 [http://www.goldcopd.org] Lacasse Y, Goldstein R, Lasserson TJ, Martin S: Pulmonary rehabilitation for chronic obstructive pulmonary...
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Báo cáo y học: " One-year treatment with mometasone furoate in chronic obstructive pulmonary disease" docx
... Longitudinal average Wheezing Baseline Longitudinal average Nighttime Symptom Scores Difficulty breathing Baseline Longitudinal average Coughing Baseline Longitudinal average Wheezing Baseline Longitudinal ... Care Med 2007, 176(6):532– 555 Chronic obstructive pulmonary disease National clinical guideline on management of chronic obstructive pulmonary disease in adults in primary and secondary care ... treatment with inhaled budesonide in persons with mild chronic obstructive pulmonary disease who continue smoking European Respiratory Society Study on Chronic Obstructive Pulmonary Disease N Engl...
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Báo cáo y học: "Open Access Changes in elastin, elastin binding protein and versican in alveoli in chronic obstructive pulmonary disease" ppt
... staining in the both alveolar wall and alveolar Figure Lung sections stained for elastin, versican and elastin binding protein Lung sections stained for elastin, versican and elastin binding ... Figure Relationship between elastin binding protein and elastin Relationship between elastin binding protein and elastin Relationship between EBP immuno-staining intensities for alveolar wall (a) ... elastin receptor: a galactosidase-binding protein Science 1988, 239:1539-1541 Mecham RP, Whitehouse L, Hay M, Hinek A, Sheetz MP: Ligand affinity of the 67-kDa elastin/laminin binding protein is...
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Báo cáo y học: "Dynamics of pro-inflammatory and anti-inflammatory cytokine release during acute inflammation in chronic obstructive pulmonary disease: an ex vivo study" pps
... [http://WWW.thoracic.org/COPD/1/definitions.asp]: Jeffery PK: Remodeling and inflammation of bronchi in asthma and chronic obstructive pulmonary disease Proc Am Thorac Soc 2004, 1(3):176-183 Cosio MG, Guerassimov A: Chronic obstructive ... decline in chronic obstructive pulmonary disease Thorax 2002, 57(10):847-852 Hurst JR, Perera WR, Wilkinson TM, Donaldson GC, Wedzicha JA: Exacerbation of chronic obstructive pulmonary disease: ... the accumulating evidence of extra pulmonary manifestations in COPD including cachexia and systemic inflammation which are observed in severe COPD patients In our model of acute inflammation...
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Báo cáo y học: "Association of current smoking with airway inflammation in chronic obstructive pulmonary disease and asymptomatic smokers" pps
... (use in epidemiology) Scand J Respir Dis 1972, 53:218-226 Global initiative for Chronic Obstructive Lung Disease NIH: Definitions chapter in Global Initiative for Chronic Obstructive Lung Disease ... Simony-Lafontaine J, Lequeu N, Vic P, Enander I, Godard P, Michel FB: Eosinophilic and neutrophilic inflammation in asthma, chronic bronchitis, and chronic obstructive pulmonary disease J Allergy Clin Immunol ... airways), which may be insufficient to obtain a full view Fourth, remodelling in COPD may itself generate and maintain an inflammatory process, independent of cigarette smoking [25] In order to elucidate...
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Báo cáo y học: "Pilot study of losartan for pulmonary hypertension in chronic obstructive pulmonary disease" ppt
... Atochina EN, Morris KG, Danilov SM, Stenmark KR: Angiotensin converting enzyme expression is increased in small pulmonary arteries of rats with hypoxia-induced pulmonary hypertension J Clin Invest ... Studies of pulmonary hypertension I Pulmonary circulatory dynamics in patients with pulmonary emphysema at rest J Clin Invest 1953, 32(2):130-7 Heath D: Remodeling of the pulmonary vasculature in hypoxic ... in particular no significant effect on arterial blood gases The rationale behind this study was based on the findings that angiotensin converting enzyme and angiotensin II are both involved in...
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Báo cáo khoa học: " Clinical review: Patient-ventilator interaction in chronic obstructive pulmonary disease" pps
... to maintain a constant Pappl, a change in any one of its determinants (Pmus or Paw) must be met by an opposite change in the other In clinical terms, this means that, for instance, increasing ... patient with severe chronic obstructive pulmonary disease Intensive Care Med 1998, 24:898-910 Sethi J, Siegel M: Mechanical ventilation in chronic obstructive lung disease Clin Chest Med 2000, ... ventilation on inspiratory muscle effort in patients with chronic obstructive pulmonary disease and acute respiratory failure Anesthesiology 1997, 86:79-91 43 Wrigge H, Golisch W, Zinserling J, Sydow...
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Báo cáo y học: "Recently published papers: Novel therapies in chronic obstructive pulmonary disease, cardiac chemicals and intensive care outcomes" ppt
... Rabe KF, Goehring U-M, Kristiansen S, Fabbri LM, Martinez FJ; for the M2-124 and M2-125 Study Groups: Roflumilast in symptomatic chronic obstructive pulmonary disease: two randomised clinical trials ... Groups: Roflumilast in moderate-to-severe chronic obstructive pulmonary disease treated with longacting bronchodilators: two randomised clinical trials Lancet 2009, 374: 695-703 Reichlin T, Hochholzer ... G, Guérin C: Six-month outcome in acute kidney injury requiring renal replacement therapy in the ICU: a multicentre prospective study Intensive Care Med 2009, in press Whitcomb DC: Clinical practice:...
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Báo cáo y học: "Another step for noninvasive ventilation in chronic obstructive pulmonary disease patients" pot
... combined with FBO in COPD with hypercapnic encephalopathy) in the most challenging patients Abbreviations COPD, chronic obstructive pulmonary disease; FBO, fibreoptic bronchoscopy; NPPV, noninvasive ... closely monitored in an intensive care unit setting and, if there is no improvement in gas exchange or vital signs within the first to hours, intubation should be planned with no delay in the best conditions ... ventilation in patients with decompensated chronic obstructive pulmonary disease due to community-acquired-pneumonia Crit Care 2010, 14:R80 Robert D, Argaud L: Clinical review: long-term noninvasive...
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Báo cáo y học: "Alterations in the muscle-to-capillary interface in patients with different degrees of chronic obstructive pulmonary disease" pps
... A, Marinari S: Systemic effects of COPD Respir Med 2005, 99(Suppl B):S3-10 Jagoe RT, Engelen MP: Muscle wasting and changes in muscle protein metabolism in chronic obstructive pulmonary disease ... anterior muscle of patients with COPD [10] This is in line with previous studies [3,7-9] and together with previous findings of a decrease in oxidative enzyme activities in COPD [6,7] our findings indicate ... alterations in the capillary bed of skeletal muscle in COPD patients Extending these findings the current study provides first evidence of a disturbed muscle- to-capillary interface expressed as CFPE-index...
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Báo cáo y học: "The Geography of Chronic Obstructive Pulmonary Disease Across Time: California in 1993 and 1999"
... of chronic obstructive pulmonary disease worldwide Monaldi Archives for Chest Disease 2001; 56: 261-264 Anto JM, Vermeire P, Vestbo J, Sunyer J Epidemiology of chronic obstructive pulmonary disease ... Int J Med Sci 2007, disease [5] How we account for these increases in rates of COPD? Chronic obstructive pulmonary disease (COPD) is a condition characterized ... (accounting for approximately one-sixth of the patient population in California), and data on patients insured at Shriner Hospital However, these insurance companies are located in urban areas in...
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Tài liệu Decline in air pollution and change in prevalence in respiratory symptoms and chronic obstructive pulmonary disease in elderly women pdf
... symptom in the development of chronic obstructive pulmonary disease [21,22] There is evidence that a reduction in air pollutants attenuates the decline in respiratory health in children The delay in ... baseline, pt prevalence at followup, E baseline exposure at baseline, ΔE exposure decline (exposure at baseline minus exposure at follow-up), t follow-up time, Sbaseline smoking at baseline (yes ... lung aging was accelerated in the highly polluted areas at baseline The results at follow up demonstrate that the increase in lung aging in these areas was attenuated due to a steep decline in air...
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