pathology prognosis and staging of breast cancer
Guidelines for the early detection and screening of breast cancer ppt
... developing breast cancer Worldwide, 75% of new cases and 84% of breast cancer deaths occur in women aged 50 and older, with the number of breast cancers diagnosed in women in their fourth decade of life ... risks of heart attack, breast cancer and potentially life-threatening blood clots 16 Guidelines for the early detection and screening of breast cancer Hip fractures Colon cancer Breast cancer ... member of this team Guidelines for the diagnosis and treatment of breast cancer are further elaborated in Guidelines for management of breast cancer (2006)1 Guidelines for management of breast cancer, ...
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Tài liệu Tamoxifen for Prevention of Breast Cancer: Report of the National Surgical Adjuvant Breast and Bowel Project P-1 Study pdf
... mammographic and pathologic examination Therefore, she was not at risk for development Fig Example of a breast cancer risk profile NSABP סNational Surgical Adjuvant Breast and of breast cancer and ... of invasive breast cancer were calculated for several subgroups of women When age, history of LCIS, history of atypical hyperplasia, and levels of predicted risk of breast cancer were taken into ... age, history of lobular carcinoma in situ (LCIS), history of atypical hyperplasia, 5-year predicted breast cancer risk, and number of first-degree relatives with breast cancer No of events Rate...
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Mammography and Beyond: Developing Technologies for the Early Detection of Breast Cancer pptx
... of developing breast cancer Thus, the lifetime risk of developing breast cancer is 14.4 percent, whereas the absolute risk of developing breast cancer over the decade between the ages of 40 and ... displays and workstation design for improved image interpretation Discovery of molecular profiles toward goal of precise molecular diagnosis of cancer Breast cancer is one of eight cancers targeted ... Watercolor and ink http:/www.breastcancerfund.org/gallery_6.html Art Rage Us The Art and Outrage of Breast Cancer National Academy of Sciences National Academy of Engineering Institute of Medicine...
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Factors infl uencing the risk of breast cancer – established and emerging ppt
... for breast cancer, and as effect modifiers of the association of fat intake and risk of breast cancer Cancer Causes Control, 8, pp49-56 18 Collaborative Group on Hormonal Factors in Breast Cancer ... The protective role of pregnancy in breast cancer Breast Cancer Res., 7(3), pp131-42 20 Collaborative Group on Hormonal Factors in Breast Cancer (2002b) Breast cancer and breastfeeding: collaborative ... Risk of breast cancer in relation to lifetime alcohol consumption J Natl Cancer Inst., 87, pp923-929 35 Cancer Research UK (2007) About breast cancer: Breast cancer risks and causes http://www.cancerhelp.org.uk/help/default.asp?page=3285...
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Mouse models of breast cancer metastasis: Anna Fantozzi and Gerhard Christofori pdf
... initial spreading of cancer cells to local lymph nodes via the lymphatics in human breast cancer Another important aspect to the understanding of breast cancer metastasis is the role of different ... receptors and cancer: the complexity of targeted inhibitors Nat Rev Cancer 2005, 5:341-354 Cavallaro U, Christofori G: Cell adhesion and signalling by cadherins and Ig-CAMs in cancer Nat Rev Cancer ... and cyclin D1 in late-stage metastatic cancer [47] The MMTV-PyMT mouse model of breast cancer is furthermore characterized by short Page of 11 (page number not for citation purposes) Breast Cancer...
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Detection of breast cancer cells using targeted magnetic nanoparticles and ultra-sensitive magnetic field sensors potx
... varying levels of Her2, including breast cancer cell lines MCF7/Her2-18 Hathaway et al Breast Cancer Research 2011, 13:R108 http:/ /breast- cancer- research.com/content/13/5/R108 A Page of 13 B Figure ... followed by BT-474 breast cancer cells (2.75 × 106), MCF7 breast cancer cells (0.18 × 106), and MDA-MB-231 breast cancer cells (0.11 × 106) The Chinese hamster ovary (non -breast) cell line has ... the detection of proteins and protein complexes: quantitation of HER1 and HER2 total protein expression and homodimerization in formalin-fixed, paraffinembedded cell lines and breast cancer tissue...
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báo cáo khoa học: "Surgical perspectives from a prospective, nonrandomized, multicenter study of breast conserving surgery and adjuvant electronic brachytherapy for the treatment of breast cancer" pps
... Wang Y, Early Breast Cancer Trialists’ Collaborative Group (EBCTCG): Effects of radiotherapy and of differences in the extent of surgery for early breast cancer on local recurrence and 15-year ... communities and receive state of the art breast radiotherapy as an adjunct to modern breast conserving surgery Conclusions Early stage breast cancer can be treated with breast conserving therapy and ... from a prospective, nonrandomized, multicenter study of breast conserving surgery and adjuvant electronic brachytherapy for the treatment of breast cancer World Journal of Surgical Oncology 2011...
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Báo cáo khoa học: "The combination effect of sodium butyrate and 5-Aza-2''''-deoxycytidine on radiosensitivity in RKO colorectal cancer and MCF-7 breast cancer cell lines" pot
... human colon and breast cancer cell lines were used to determine the effects of the demethylation agent, 5-Aza-2'deoxycytidine (5-aza-DC), and the HDAC inhibitor, sodium butyrate (SB), and the two ... on radiosensitivity Materials and methods Cell line culture and reagents Human colon cancer cell lines RKO (ATCC, USA), breast cancer cell line MCF-7 (KCLB, Korea), and normal colon cell line DDC-112 ... After 24 hours of seeding of × 103 cells each DDC-112 CoN, RKO, and MCF7 in a 96-well plate, 5-Aza-2'-deoxycytidin uM, sodium butyrate mM, and a combination of both were added and then cultivated...
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Báo cáo khoa học: "Skin invasion and prognosis in node negative breast cancer: a retrospective study" pps
... literature, and drafted the manuscript FA and RH contributed to the pathology analysis and pathological part of the manuscript drafting HM, KI, YM, SN, MM, and TI participated in this study's design and ... Nicolaou N, Anderson P, Hoffman J, Sigurdson E, Boraas M, Torosian M: Accuracy of the extent of axillary nodal positivity related to primary tumor size, number of involved nodes, and number of nodes ... without positive lymph nodes Cancer 1986, 57(3):622-629 Carter CL, Allen C, Henson DE: Relation of tumor size, lymph node status, and survival in 24,740 breast cancer cases Cancer 1989, 63(1):181-187...
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báo cáo khoa học: "Effects of ulinastatin and docetaxel on breast cancer invasion and expression of uPA, uPAR and ERK" docx
... Growth of Xenograft Breast Cancer and Expression of CXCR4 and MMP-9 in Cancers The Journal of International Medical Research 2010, 38:967-976 Gao F, Sun ZJ: Progress in the correlation of vascular ... docataxel on breast tumor growth and expression of IL6, IL-8, and TNF-a Journal of Experimental & Clinical Cancer Research 2011, 30:22 Sun ZJ, Yu T, Chen JS: Effects of Ulinastatin and Cyclophosphamide ... Proliferation and invasion are important biological features of breast cancer Because the development of breast cancer involves many extremely complicate regulatory factors, its treatment is often difficult...
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báo cáo khoa học: "Predicting prognosis of breast cancer with gene signatures: are we lost in a sea of data?" docx
... class and prognosis, it is no longer surprising that comparing gene-expression profiles of breast cancers that recurred (mostly the ERnegative and the high grade, ER-positive cancers) and those ... the prognosis of ER-positive breast cancers relatively accurately because prognosis is closely related to the proliferative status of these cancers and proliferation affects the expression of ... prognosis in estrogen receptor-negative and HER2-positive breast cancers Breast Cancer Res 2009, 11:R15 doi:10.1186/gm202 Cite this article as: Iwamoto T, Pusztai L: Predicting prognosis of breast...
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Báo cáo y học: " Intracystic papillary carcinoma in a male as a rare presentation of breast cancer: a case report and literature review" potx
... his left breast He also had a significant family history for breast cancer including a maternal grandmother, two of his maternal aunts and a maternal first cousin diagnosed with breast cancer On ... to receive radiotherapy and tamoxifen [14] Page of (page number not for citation purposes) Journal of Medical Case Reports 2009, 3:13 Between 4% and 40% of male breast cancers might result from ... management of intracystic papillary carcinoma of the breast: the roles of radiation and endocrine therapy Am J Surg 2007, 194:497-500 Fentiman IS, Fourquet A, Hortobagyi GN: Male breast cancer Review...
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the role of ikkalpha, ikkbeta and nf-kappab in the progression of breast cancer
... Tables Table 1.1: Survival rates of breast cancer in Scotland by age range 19 Table 1.2: TNM staging of breast cancer 25 Table 1.3: Subtypes of breast cancer based on routine IHC markers ... prognosis and patients with a score of >5.4 have a poor prognosis [35-36] 1.1.5.3 Clinical stages of breast cancer Breast cancer can present at several stages at diagnosis from early breast cancer ... Introduction 17 1.1 Breast cancer epidemiology, pathology and prognostic factors 1.1.1 Breast cancer incidence, mortality and survival Breast cancer is the most common female cancer in the UK with...
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EFFECTS OF INHIBITING THE MAMMALIAN TARGET OF RAPAMYCIN (MTOR) PATHWAY AND TELOMERASE IN BREAST CANCER CELLS
... stage and metastatic breast cancers (Ferte, Andre et al 2010) 1.4.2 Telomerase in breast cancer Up to 90% of all breast cancers express activation of telomerase enzyme, and there is a progressive ... activation of the PI3K/Akt/mTOR pathway in breast cancers mostly occurs via HER2, ER, IGF and lack of PTEN, and some or all of these may be factors that sensitize breast cancer cells to rapamycin and ... with diagnosis, and poorer prognosis and survival of breast cancer patients (Clark, Osborne et al 1997; Mokbel, Parris et al 2000; Hiyama and Hiyama 2004) 1.4.3 Rapamycin in breast cancer Rapamycin...
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In vivo and in vitro study on potential combination therapy of COL 3 and tamoxifen in breast cancer a pilot study
... combination of tamoxifen and COL-3 is rational, based on the marked antitumor activity of both agents against a variety of solid tumors, such as breast cancer, prostate cancer, lung cancer, colon cancer, ... past decade Given the understanding of the basic biology of breast cancer, the pending revolution in our ability to finely subtype it, and the availability of hundreds of novel agents, it seems ... node-negative breast carcinoma[113] COL-3 is devoid of antimicrobial properties and is a competitive and selective inhibitor of MMP-2 and MMP-9 isoenzymes, making it an attractive candidate for clinical breast...
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Management of breast cancer in women: A national clinical guideline ppt
... care and treatment of breast cancer Clinical practice guidelines for the care and treatment of breast cancer: 14 The role of hormone replacement therapy in women with a previous diagnosis of breast ... have been inconclusive, and where there are indications that MRI is useful MANAGEMENT OF BREAST CANCER IN WOMEN 2.3.2 staging of breast cancer In early operable breast cancer (T1-2, N0-1; see ... Email: sco@breastcancercare.org.uk • www.breastcancercare.org.uk Breast Cancer Care provides information, practical assistance and emotional support for anyone affected by breast cancer CancerBACUP...
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Lung cancer - The diagnosis and treatment of lung cancer pdf
... after breast cancer Survival rates for lung cancer are very poor In England, for patients diagnosed between 1993 and 1995 and followed up to 2000, 21.4% of men and 21.8% of women with lung cancer ... to lung cancer in 2002 Lung cancer is the most common cause of cancer death for men, who account for 60% of lung cancer cases In women, lung cancer is the second most common cause of cancer death ... D NICE Guideline – lung cancer 21 1.10.13 The opinions and experiences of lung cancer patients and carers should be collected and used to improve the delivery of lung cancer services Patients...
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Early and locally advanced breast cancer: diagnosis and treatment pdf
... topic of breast cancer in October 2003 as part of NICE’s ninth wave work programme Because of the size of this topic, the NCC-C used guideline slots (early breast cancer and advanced breast cancer) ... assessment and psychological support Introduction to Breast Cancer Referral and Diagnosis Preoperative Assessment of the Breast and Axilla Preoperative Staging of the Axilla Providing Information and ... Scotland, 2008; and Northern Ireland Cancer Registry, 2008 Reproduced with permission of Cancer Research UK 1.3 Prognosis3 Breast Cancer Clinical Outcome Measures’ (BCCOM) audit (2007) of more...
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Early and locally advanced breast cancer - Diagnosis and treatment pdf
... quality of psychological approaches and services offered to patients with breast cancer As a consequence of the diagnosis of breast cancer at least a quarter of patients report anxiety and depression ... Introduction Breast cancer is the most common cancer for women in England and Wales, with about 40,500 new cases diagnosed 1, and 10,900 deaths1, recorded in England and Wales each year In men breast cancer ... Early and locally advanced breast cancer 21 1.12 Primary systemic therapy Early breast cancer 1.12.1 Treat patients with early invasive breast cancer, irrespective of age, with surgery and appropriate...
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Guidelines for management of breast cancer ppt
... Management of metastatic disease Staging of metastatic or recurrent breast cancer The staging evaluation of women presenting with metastatic or recurrent breast cancer includes the performance of a ... of breast cancer Figure 12 Bilateral breast cancer Management of special problems in breast cancer Figure 13 Paget’s disease of the nipple-areola complex Figure 14 Cancer of the male breast: diagnosis ... score ≥ 75% of the tumour is composed of tubules score 10%–75% of the tumour is composed of tubules score < 10% of the tumour is composed of tubules Pathological handling of breast cancer excision...
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