pathology of skeletal muscle
Tài liệu Báo cáo khoa học: Effect of gadolinium on the ryanodine receptor/ sarcoplasmic reticulum calcium release channel of skeletal muscle docx
Ngày tải lên :
19/02/2014, 16:20
... Regulation of the rat sarcoplasmic reti-
culum calcium release by calcium. J Muscle Res Cell
Motil 21, 131–138.
20 Lai FA & Meissner G (1990) Structure of the calcium
release channel of skeletal muscle ... presence of 18 nm ryanodine
and the amount of ryanodine bound was plotted
against the concentration of the gadolinium (Fig. 7).
Fitting of data points with the Hill equation revealed a
K
d
value of ... Coronado
R (1988) Ryanodine receptor of skeletal muscle is a gap
junction-type channel. Science 242, 99–102.
13 Sitsapesan R & Williams AJ (1995) The gating of the
sheep skeletal sarcoplasmic reticulum...
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Báo cáo khoa học: Cardiac ankyrin repeat protein is a marker of skeletal muscle pathological remodelling pot
Ngày tải lên :
07/03/2014, 03:20
... standardization
of the loading. (D) Weights of injected TA muscles (n = 13) were compared to those of control samples. No significant difference was
observed. (E) Histological analyses of muscles. Frozen ... obtain denervation of the muscle of the lower limb,
the dorsal skin of the thigh of 2-month-old male
129SvPasIco mice (n = 6 for each time point) was cut,
and the posterior muscles were split ... was
checked at the time of muscle excision by visualization of
abnormal gait of the limb and by verifying the disconti-
nuity of the sciatic nerve at the thigh. The TA, EDL and
soleus muscles were sampled...
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Báo cáo khoa học: Mapping contacts between regulatory domains of skeletal muscle TnC and TnI by analyses of single-chain chimeras potx
Ngày tải lên :
16/03/2014, 18:20
... domain of TnC [33]. The crystal structure of
cTn [20] showed that residues R117 to L128 of TnI (in
chicken fast skeletal numbers) are in close contact with
the N domain of TnC in the presence of ... terminus of
TnI has a tubular-like conformation that involves the
globular N domain of TnC. NMR studies have provi-
ded additional information on the structure of skeletal
TnC(1–91) in the presence of ... structure of TnI and TnC that can explain
how they interact during muscle contraction. Figure 6
shows a schematic representation of the structural dis-
position of TnC and TnI in the light of recent...
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Báo cáo Y học: Fluorescence study of the high pressure-induced denaturation of skeletal muscle actin pdf
Ngày tải lên :
24/03/2014, 00:21
... release
of ADP
depolymerised actin
denatured
actin
random aggregation
after release of pressure
[1]
[2]
[3]
Fig. 12. Schematic interpretation of the
behaviour of F-actin in the presence of free ... 250 MPa.
However, the increase of intensity of ¯uorescence of eATP
buffer itself was much smaller than that of eATP bo und to
G-actin. Therefore, the increase of ¯uorescence seems to b e
due ... the
centre of spectral mass of intrinsic ¯uorescence spectrum of
G-actinwithATP(0.5mgámL
)1
, p H 7.5) in a pressure
range from 0.1 MPa to 400 MPa at a ®xed temperature of
20 °C. The transition of the...
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Tài liệu Báo cáo khoa học: Subproteomics analysis of Ca2+-binding proteins demonstrates decreased calsequestrin expression in dystrophic mouse skeletal muscle pdf
Ngày tải lên :
19/02/2014, 16:20
... viscosity of t he extract as a result of D NA, 2 lLof
DNase I (200 units) was added per 100 lL of buffer [30].
Following filtration through two layers of miracloth a nd the
addition of four volumes of ... used
were of analytical grade and purchased from Sigma
Chemical Company.
Preparation of total muscle extracts
For the comparative gel electrophoretic analysis of normal
vs. dystrophic skeletal muscle ... analysis of Fig. 3 and the 1D i mmunoblotting of Fig. 4.
As the full-length Dp427 isoform of dystrophin does not
enter the second dimension of conventional 2D gels, the
expression level of a-dystroglycan...
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Báo cáo khoa học: Progressive decrease of phosphocreatine, creatine and creatine kinase in skeletal muscle upon transformation to sarcoma pot
Ngày tải lên :
07/03/2014, 06:20
... 4. Immunoblot of CK isoforms of different post-operative
human tissues. (A) Immunoblot of MCK (a) and sMitCK (b) of nor-
mal muscle (N) and fibrosarcoma (T) tissue. (B) Immunoblot of BCK
(a) and ... Expression of mRNA of MCK and sMitCK isoforms of crea-
tine kinase and b-actin in normal muscle (NM) and 3MC induced
sarcoma tissue (ST) of mouse.
1.0
0.8
0.6
0.4
0.2
Relative expression of mRNA
0.0
N
MCK ... that because of the low
abundance of MCK and sMitCK isoenzymes in
sarcoma, a much higher amount of protein had to be
applied compared with normal muscle.
Detection of BCK and uMitCK isoforms in...
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![báo cáo hóa học: " Influence of dietary state and insulin on myocardial, skeletal muscle and brain [18F]fluorodeoxyglucose kinetics in mice" pptx](https://media.store123doc.com/images/document/2014_06/21/medium_buu1403292011.jpg)
Báo cáo y học: "Skeletal muscle sodium glucose co-transporters in older adults with type 2 diabetes undergoing resistance training"
Ngày tải lên :
31/10/2012, 17:08
... support the postulated sensing activity of hSGLT3
[33] in skeletal muscle. However, the increased
expression of hSGLT3 in skeletal muscle we found after
16 weeks of resistance exercise without a ... predictor of hSGLT3
transcript levels, explaining 68% of its variability (P=0.01). Our data show that hSGLT3, but not GLTU4, expression
was enhanced in skeletal muscle after 16 weeks of resistance ... important factor.
Exercise, the major physiological activator of muscle
glucose transport, regulates the expression of GLUT4 in
skeletal muscle [3, 4], and induces its translocation from
the intracellular...
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Báo cáo y học: "Introduction into Pathology of Ocular Zoonoses"
Ngày tải lên :
03/11/2012, 11:11
... into Pathology of Ocular Zoonoses
Hans E. Schaefer
Institute of Pathology - University of Freiburg im Breisgau (Germany)
Published: 2009.03.19
Zoonosis: what does it mean?
The meaning of the ...
consequence of cystic larval growth and inflammatory
reaction due to eventual necrosis of parasites. -
Analogous intraocular lesions may be caused by
coenuriasis, the larval stage of tape worms of ... Organization produced an
official definition of Zoonosis as: “diseases transmit-
ted in a natural way from vertebrate animals to hu-
mans”. Currently, three subtypes of Zoonoses may be
distinguished:
...
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Tài liệu Report on The Management of Non-Muscle-Invasive Bladder Cancer ppt
Ngày tải lên :
14/02/2014, 21:20
... TL,
Catalona WJ. Long-term followup of patients treated
with 1 or 2, 6-week courses of intravesical bacillus
Calmette-Guerin: analysis of possible predictors of
response free of tumor. J Urol 1990;144(3):652-7.
Cordon-Cardo ... but
most recurrences of non -muscle- invasive bladder
cancer (especially of initially diagnosed grade 1,
stage Ta disease) are not muscle invasive and car-
ry relatively little risk of metastasis or ... intravesical thiotepa in the
management of non-invasive carcinoma of the blad-
der. J Urol 1981;125(3):307-12.
Koss LG. Tumors of the urinary bladder. In Atlas of
tumor pathology, second series, fascicle...
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Tài liệu Báo cáo khoa học: Thermal unfolding of smooth muscle and nonmuscle tropomyosin a-homodimers with alternatively spliced exons docx
Ngày tải lên :
19/02/2014, 07:20
... may also occur in nonmuscle Tm
isoforms due to replacement of the N-terminal muscle
exon 1a by nonmuscle exon 1b.
The noncooperative unfolding of a significant part of
the nonmuscle Tm molecule ... to isoform type. In mam-
malian cells, alternative splicing produces a variety
of muscle and nonmuscle isoforms from four differ-
ent genes [1]. Muscle cells express two major iso-
forms of Tm ... to investigate thermal unfolding of recombinant fibroblast isoforms
of a-tropomyosin (Tm) in comparison with that of smooth muscle Tm.
These two nonmuscle Tm isoforms 5a and 5b differ internally...
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Báo cáo khoa học: Equilibrium distribution of skeletal actin–tropomyosin– troponin states, determined by pyrene–tropomyosin fluorescence potx
Ngày tải lên :
07/03/2014, 09:20
... states of
regulated actin are important determinants of the regu-
lation of striated muscle contraction. The distribution
of these states determines the ATPase activity, whereas
the rates of transitions ... troponin T,
troponin I and troponin C, which bind along actin fila-
ments of skeletal and cardiac muscles. Activation of
striated muscle contraction occurs when Ca
2+
binds to
troponin C, or in a Ca
2+
-independent ... reliable meth-
ods of determining the state of actin in real time. This
manuscript explores, in detail, a well-known method of
monitoring the state of regulated actin.
The fraction of actin in the...
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Muscle Growth GuideAuthor: Darren O ConnellBrought to you by http://www.explosivemusclegrowth.com.Muscle Growth GuideTable of Contents2 Muscle Building Secrets Guaranteed to Add Muscle Mass!.......................................................... pptx
Ngày tải lên :
08/03/2014, 14:20
... triceps.
17
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