p63 overexpression associated with poor prognosis in head and neck squamous cell carcinoma
Báo cáo sinh học: "Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" pot
... Her3/erbB3, and Her4/erbB4).All share a common structure, with an extracellularligand-binding domain, a transmembrane domain, and an intracytoplas mic tyrosine kinase domain[3-5]. Ligandbinding to ... staining (data notshown). Her2 staining was scored based on the scoringsystem applied to breast cancers, with scores of 0,+1,+2, +3 for increas ing intensity and “ continuity” of stain-ing ... Her3 and Her2 staining respectively. To minimizenon-specific staining, the section was incubated with protein block (DakoCytomation) for 15 min. After wash-ing with TBST, the specimen was incubated...
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báo cáo hóa học:" Membranous expression of Her3 is associated with a decreased survival in head and neck squamous cell carcinoma" doc
... Her3/erbB3, and Her4/erbB4).All share a common structure, with an extracellularligand-binding domain, a transmembrane domain, and an intracytoplas mic tyrosine kinase domain[3-5]. Ligandbinding to ... that arise in the head and neck region are s quamous cell carcin omas arising from theupper aerodigestive tract epithelium. Progressive localspread of head and neck squamous cell carcinoma (HNSCC) ... staining (data notshown). Her2 staining was scored based on the scoringsystem applied to breast cancers, with scores of 0,+1,+2, +3 for increas ing intensity and “ continuity” of stain-ing...
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Báo cáo sinh học: " Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas" potx
... detect ed in up to 72% of oropharyn gealcancers [3]. Further, tobacco and alcohol consumptionis implicated in 75% of head and neck squamous cell carcinomas (HNSCC) [4,5]. Thus, infection and inflam-mation ... as overcoming theimmune defect induced by deficient TLR4 signaling b ycombining chemotherapy with alternate TLR4 agonists.Abbreviations(HNSCC): Head and neck squamous cell carcinomas; (TLR): ... receptor 4 single-nucleotidepolymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomasChristoph Bergmann1*, Hagen S Bachmann2, Agnes Bankfalvi3, Ramin Lotfi4, Carolin Pütter5,...
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báo cáo hóa học:" Toll-like receptor 4 single-nucleotide polymorphisms Asp299Gly and Thr399Ile in head and neck squamous cell carcinomas" doc
... as overcoming theimmune defect induced by deficient TLR4 signaling b ycombining chemotherapy with alternate TLR4 agonists.Abbreviations(HNSCC): Head and neck squamous cell carcinomas; (TLR): ... Thr399Ile in head and neck squamous cell carcinomas. Journal of Translational Medicine 2011 9:139.Submit your next manuscript to BioMed Central and take full advantage of: ã Convenient online submissionã ... stainingStainedsectionswerereviewedbyoneoftheauthors(AB). The percentage of tumor cells showing a positivemembranous/cytoplasmatic staining and the intensity ofstaining were assessed. Cases with complete lack ofstaining were scored as negative,...
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Báo cáo khoa học: "Recurrence patterns of locally advanced head and neck squamous cell carcinoma after 3D conformal (chemo)-radiotherapy" pdf
... radiochemotherapy in advanced-stage oropharynx carcinoma. J Clin Oncol 2004, 22(1):69-76.22. Kreimer AR, Clifford GM, Boyle P, Franceschi S: Human papillomavirustypes in head and neck squamous cell carcinomas ... Urba S, Lin A, Schipper MJ, Wolf GT: Recurrences near base ofskull after IMRT for head- and- neck cancer: implications for targetdelineation in high neck and for parotid gland sparing. Int J Radiat ... radiotherapy allowing increasedGTV doses within normal tissue tolerances, and theincreasing utilization of combined chemotherapy with radiotherapy, is likely to lead increasing rates of LRC.This...
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báo cáo hóa học:" Higher percentage of CD133+ cells is associated with poor prognosis in colon carcinoma patients with stage IIIB" pptx
... with the percentage of CD133+ cells in colon carcinoma patients with Stage IIIBFigure 2The association of overall survival with the percent-age of CD133+ cells in colon carcinoma patients with ... proliferate and form a group ofcells, which invaded into the surrounding tissue, so-called"budding", and showed negative or weak staining againstCD133 (Fig 1E). Besides staining on the ... cells in the cancer nest; (C) and (D): the staining of CD133 on the luminal surface and the basal surface of cancer cells; (E): the staining of CD133 on budding cancer nest; (F): the staining...
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Báo cáo lâm nghiệp: " Fungi associated with Tomicus piniperda in Poland and assessment of their virulence using Scots pine seedlings" doc
... closely associated with T. piniperda than L. wing-fieldii in Poland. This study indicated that some populations ofT. piniperda might be more strongly associated with moulds and yeasts than with ... pine in Poland. Other Pinus species also occasionallybecome infested. Tomicus piniperda completes one generationper year. The adults overwinter in the base of pine trees or intothe soil and ... inoculating the same fungal isolates in largetrees and seedlings, found that seedling inoculation could bea reliable way of determining the virulence of bark beetle- associated blue-stain fungi in...
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Báo cáo khoa học: "Blue-stain fungi associated with Tomicus piniperda in Sweden and preliminary observations on their pathogenicity" pdf
... theblue-staining had spread.Blue-stainingVisible sapwood blue-stain developedslowly and only in a few trees (table III). In both years, only minor patches of blue-stain were ... studies using single inoculations,both L wingfieldii and O minus producedlong reaction zones and long fungal exten-sions in the bark, longest in the case of Lwingfieldii ... plates with malt agar (2% malt, 1.5% agar) and incu-bated at room temperature in darkness. In 1989, beetle attacks were again induced in pine trees of different vigour and...
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Báo cáo khoa học: "Early clinical experience with volumetric modulated arc therapy in head and neck cancer patients" ppsx
... CavityNasopharynxOropharynxHypopharynxLarynxNasal Cavity and ParanasalSinusesOther731611062Histology Squamous cell carcinoma Differentiated carcinoma Undifferentiated carcinoma Adenoidocistic carcinoma EstesioneuroblastomaSarcomas3412332Sex ... cohort, indicating that the aim of thestudy is to report about early experiences in head and neck with RapidArc, not focussing on specific outcomeor toxicity in single subgroups. It includes ... the initial clinicalexperience with head and neck RapidArc patients, in terms of dosimetric analysis and acute toxicity results.Methods and ma terialsPatients’ selectionThis is a single-Institute...
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Regenerative Medicine Reconstruction of Tracheal and Pharyngeal Mucosal Defects in Head and Neck Surgery
... against infection and invading connective tissue. There are still very few studies applying the methods of tissue engineering to produce tracheal replacements and to examine these in vitro and ... implanted skin sub-strates after cell seeding with oral keratinocytes in vitro into palatinal wounds in dogs as a model for closure of cleft palate by tissue - engineered constructs. In all six ... epithelial cells and offered a continuous supply of cells and nutrition media via a porous catheter within the scaffolds. The continuous perfusion of the tubular biodegradable scaffolds coincided with...
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Guidance on Cancer Services - Improving Outcomes in Head and Neck Cancers pot
... treatment and care ofpatients with head and neck cancer in 1998. These were updated in 2000 and substantially expanded in a new publication in 2003.56However, there is relatively little research into ... risk groups and opportunistic screening.2244Hobbs C, Birchall M. Human papillomavirus infection in the etiology of laryngeal carcinoma. Current Opinion in Otolaryngology and Head and Neck Surgery ... of head and neck cancer has permanenteffects on organs essential for normal human activities like breathing,speaking, eating and drinking. Consequently, patients facingtherapies of all kinds...
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báo cáo hóa học:" Research Article Automatic Speech Recognition Systems for the Evaluation of Voice and Speech Disorders in Head and Neck Cancer" pdf
... research and clinical purpose in order to determine the global functional outcome of speech and voice after the treatment of head and neck cancer. Itallows quantifying the intelligibility also in ... DiscussionDuring and after therapy of malignant diseases of the head and neck, communication skills are of special interest. Untilnow, no objective method with low effort and costs existedto determine ... and D. Nahamoo, “Conversational inter-face technologies, IBM Research,” in The Human-ComputerInteraction Handbook: Fundamentals, Evolving Technologies, and Emerging Applications, A. Sears and...
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Báo cáo khoa học: "F-FDG PET/CT-based gross tumor volume definition for radiotherapy in head and neck Cancer: a correlation study between suitable uptake value threshold and tumor parameters" pdf
... volume delineation in head- and- neck cancerusing CT and PET/CT fusion. Int J Radiat Oncol Biol Phys 2006, 65:726-732.31. Black QC, Grills IS, Kestin LL, Wong CY, Wong JW, Martinez AA: Defining aradiotherapy ... B,Cummings B, Dawson L, Keller A, Kim J, Ringash J, Yu E, Hendler A,Waldron J: Intraobserver and interobserver variability in GTV delineationon FDG-PET-CT images of head and neck cancers. Int ... determined whenusing 15% isodensity volumes (green line). CT-based GTV wasoutlined by red line.Figure 3 The BTV of the primary tumor was determined whenusing 20% isodensity volumes (pink line)....
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Báo cáo khoa học: "Dysphagia in head and neck cancer patients following intensity modulated radiotherapy (IMRT)" pptx
... Spencer SA, Bonner JA:Dosimetric Factors Associated With Long-Term Dysphagia AfterDefinitive Radiotherapy for Squamous Cell Carcinoma of the Head and Neck. International Journal of Radiation Oncology*Biology*Physics ... Phys 2008,72:1119-1127.16. Dirix P, Nuyts S: Value of Intensity-Modulated Radiotherapy in Stage IV Head- and- neck Squamous Cell Carcinoma. International Journal ofRadiation Oncology*Biology*Physics ... Group(RTOG) phase III randomized study to compare hyperfractionation and two variants of accelerated fractionation to standard fractionationradiotherapy for head and neck squamous cell carcinomas: first...
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