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orally induced tolerance to nickel the role of oral exposure orthodontic devices in preventing sensitization

Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf

Báo cáo khoa học: Use of lithium and SB-415286 to explore the role of glycogen synthase kinase-3 in the regulation of glucose transport and glycogen synthase pdf

Báo cáo khoa học

... of GSK3 (using Li or SB-415286) appears to be sufficient for inducing activation of GS in muscle and fat cells, and that inhibition of the kinase potentiates insulin action in muscle of insulin-resistant ... phosphatidylinositol 3-kinase, p70, S6 kinase and glycogen synthase kinase-3 activity in L6 muscle cells: evidence for the involvement of the mammalian target of rapamycin (mTOR) pathway in the L-leucine -induced ... significant increase in glucose uptake would tend to negate this possibility (Fig 7B) To further investigate whether inactivation of GSK3 has any regulatory input into the stimulation of glucose...
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Bringing the Hidden Giants to the Footlight: the Role of Savings and Retail Banks in Increasing the Level of Access to Financial Services docx

Bringing the Hidden Giants to the Footlight: the Role of Savings and Retail Banks in Increasing the Level of Access to Financial Services docx

Ngân hàng - Tín dụng

... program in wholesale lending to microfinance institutions for lending to their micro borrowers Savings banks could refinance well-functioning microfinance institutions individually or indirectly ... businesses, the traditional target client group of savings banks By capturing and channelling more of the remittances into the financial system and intermediating the flow of the resources, savings ... disbursing of loans and collecting loan repayments Another promising track for savings banks is to invest their savings deposits in microfinance institutions by specialising 18 Microfinance Information...
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báo cáo hóa học:

báo cáo hóa học:" A lifeline to treatment: the role of Indian generic manufacturers in supplying antiretroviral medicines to developing countries" pptx

Hóa học - Dầu khí

... block international trade in generic medicines when they are suspected of infringing patents in the countries through which they transit These types of Page of border measures blocked medicines ... the prominence of Indian generic manufacturers in the supply of antiretroviral medicines to developing countries Since 2006, Indian-produced generic ARVs have accounted for more than 80% of the ... article as: Waning et al.: A lifeline to treatment: the role of Indian generic manufacturers in supplying antiretroviral medicines to developing countries Journal of the International AIDS Society 2010...
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From Conflict to Peacebuilding The Role of Natural Resources and the Environment pdf

From Conflict to Peacebuilding The Role of Natural Resources and the Environment pdf

Điện - Điện tử

... conflict, resulting in the release of 80,000 tonnes of burning oil into the environment Black rain reportedly fell onto neighbouring towns and villages In addition, a toxic cocktail of compounds ... resources in international trade in order to minimize the potential for these resources to finance conflict International sanctions should be the primary instrument dedicated to stopping the trade in ... protection of the environment in times of armed conflict; […] to take steps to incorporate the provisions of international law applicable to the protection of the environment into their military...
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báo cáo khoa học:

báo cáo khoa học: "A Study to investigate the role of p27 and Cyclin E immunoexpression as a prognostic factor in early breast carcinoma" pptx

Báo cáo khoa học

... of cyclin E shortens the length of G1, accelerating progression of the cell cycle into the S phase [4] The activation of cyclin E is mediated through its activation of the cyclin dependant kinase ... mounted onto positively charged slides to prevent lifting of sections during heat induced epitope retrieval (HIER) Epitope retrieval involved bringing the specific buffer to boiling point in a pressure ... cyclin E in all invasive carcinomas and in the subgroup of IDC This may be due to the early stage of the disease The major limitation of this study is the small size of the study group Further...
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Báo cáo y học:

Báo cáo y học: " The role of poly (ADP-ribose) polymerase in ventilator-induced lung injury" ppsx

Báo cáo khoa học

... Kang EH, Lee SY, Suh IB, Shin C, Shim JJ, In KH, Yoo SH, Kang KH: Inflammatory and transcriptional roles of poly (ADP-ribose) polymerase in ventilator -induced lung injury Crit Care 2008, 12:R108 ... volume, which might not be clinically relevant, is frequently necessary to induce appropriate lung injury Competing interests The authors declare that they have no competing interests References Kim ... ventilation in healthy mice induces reversible pulmonary and systemic cytokine elevation with preserved alveolar integrity: an in vivo model using clinical relevant ventilation settings Anesthesiology...
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Báo cáo y học:

Báo cáo y học: " Using Geographic Information Systems (GIS) to assess the role of the built environment in influencing obesity: a glossary" pptx

Báo cáo khoa học

... contributed to the study design and the redrafting of the paper All authors read and approved the final version of the final paper Competing interests The authors declare that they have no competing interests ... acquisition of the location of features within the built environment such as food stores, parks or outdoor advertising [31] GPS devices also enable investigators to track the mobility patterns of individuals ... in the area, and their ability to travel within and beyond the boundary of the administrative unit GIS has improved measurements of accessibility by enabling the creation of more refined individual-level...
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A study to investigate the involvement of nadph oxidase 5 (NOX5) in resveratrol (RSV)   induced reactive oxygen species (ROS) production in u937 cells

A study to investigate the involvement of nadph oxidase 5 (NOX5) in resveratrol (RSV) induced reactive oxygen species (ROS) production in u937 cells

Tổng hợp

... aimed to investigate the involvement of RSV -induced ROS production in regulating NOX5 expression in the U937 lymphoma cells The initial part of the study involved analyzing the expression of NOX5 ... of selenium-containing enzymes involved in the removal of H2O2 via the coupling of its reduction to the oxidation of glutathione (GSH) GSH is a thiol-containing tripeptide The oxidized form of ... part in host defense in the event of an infection due to the entry of microorganism (Bedard and Krause, 2007) Another major role of NOX enzymes would be in regulating the levels of pro-inflammatory...
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The Role of Genetically Modified Organisms (GMOs) in Beverage Production

The Role of Genetically Modified Organisms (GMOs) in Beverage Production

Môi trường

... throughout the world bears little resemblance to teosinte, the original ancestor of corn The newer techniques involving genetic engineering, on the other hand, allow for the transfer of a few genes in ... consumed in place of saturated fatty acids It is possible to increase the content of vitamin E, a natural antioxidant, and to insert the capability of producing plant-based omega-3 fatty acids into ... recombinant bovine somatotropin IDENTITY PRESERVATION AND THE INTERNATIONAL MARKET In the past, it was not necessary for the food supply chain to segregate and identity preserve grain destined...
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Tài liệu THE VALUE OF IMPROVED PUBLIC SERVICES: AN APPLICATION OF THE CHOICE EXPERIMENT METHOD TO ESTIMATE THE VALUE OF IMPROVED WASTEWATER TREATMENT INFRASTRUCTURE IN INDIA docx

Tài liệu THE VALUE OF IMPROVED PUBLIC SERVICES: AN APPLICATION OF THE CHOICE EXPERIMENT METHOD TO ESTIMATE THE VALUE OF IMPROVED WASTEWATER TREATMENT INFRASTRUCTURE IN INDIA docx

Kế toán - Kiểm toán

... employed to explain the choice of the wastewater treatment programme alternative, and the vector of coefficients to l are attached to the vector of interaction terms (S) that influence utility Since ... nevertheless in the meanwhile the results of this study disclose that, despite their tight budget constraints the local public value improvements in the quality of the water in the Ganga and if the ... water The remaining untreated wastewater is discharged to the Ganga, creating environmental pollution and negatively affecting the sustainability of the ecosystem functions of the river There is therefore...
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The Role of Small and Large Businesses in Economic Development doc

The Role of Small and Large Businesses in Economic Development doc

Tài chính doanh nghiệp

... misleading to measure net employment changes as total employment in a size class at the end of the year less total employment in the size class at the beginning of the year The numbers presented in ... other inducements is to focus on the small business sector Perhaps the greatest generator of interest in entrepreneurship and small business is the widely held belief that small businesses in ... uncomfortably unable to explain it, or at least the part of it that is not explained by observable indicators of labor quality.” Other theories to explain the size-wage effect have surfaced since the Brown...
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Báo cáo khoa học: The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase pptx

Báo cáo khoa học: The role of evolutionarily conserved hydrophobic contacts in the quaternary structure stability of Escherichia coli serine hydroxymethyltransferase pptx

Báo cáo khoa học

... helix of the third cluster of CHCs is part of the inter-domain segment and the other helix lines the boundary between the major domain and the N-terminus (Fig 1) Therefore, the formation of the ... PLP binding properties The affinity of wild-type and mutant forms for the cofactor was measured to evaluate the impact of the mutations on the structure of the PLP binding site Because PLP binding ... located in the cores of the large and small domains, respectively, and appear to stabilize their protein scaffolds, allowing the proper positioning of the residues involved in PLP binding, substrate...
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The Role of Gestures and Facial Cues in Second Language Listening Comprehension pptx

The Role of Gestures and Facial Cues in Second Language Listening Comprehension pptx

Kỹ năng nghe tiếng Anh

... memory for the listening comprehension task In addition, to keep the content coherent within each clip, the length of each varied from to The subtopics of the five clips were (a) the history of ceramics, ... lecture outline in advance, and to expand on or omit some of the material to ensure a more natural delivery with minimal reference to the outline during recording The first part of the lecture ... and phrases in an outline rather than full sentences to be read She did not need to make frequent reference to the outline because of her knowledge of the topic The transcript of the clip (see...
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Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx

Báo cáo Y học: Elucidation of the role of fructose 2,6-bisphosphate in the regulation of glucose fluxes in mice usingin vivo 13 C NMR measurements of hepatic carbohydrate metabolism docx

Báo cáo khoa học

... the initial rate of label incorporation into glycogen C6 relative to the rate of label incorporation into glycogen C1 reflects the relative isotopic enrichment of Glc6P in the C6 relative to the ... is indicative of activated 6-phosphofructo-1-kinase, which can lead to increased 13C labeling at the triose level Such a mechanism can lead to increases in labeling of glycogen C6 even in the ... inserted into the tail veins, one for the administration of pentobarbital and one for the infusion of glucose A third catheter was placed intraperitoneally as an alternative means of glucose administration...
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Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf

Báo cáo Y học: The role of hydrophobic active-site residues in substrate specificity and acyl transfer activity of penicillin acylase pdf

Báo cáo khoa học

... thereof, while maintaining the hydrophobicity of the binding site To test the effect of the mutations on the specificity for phenylacetylated substrates, the steady-state kinetic parameters for the ... more insight into the structural features underlying the kinetic properties of these enzymes The reduced amidase activity of bF24A in uences the factor a, a key parameter for the synthesis of antibiotics ... results indicate that mutating bF57, which is located ˚ at the bottom of the binding pocket at A from the nucleophilic serine, does in uence the rate of formation of the acyl-enzyme, as judged by the...
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The role of floating-rate bank loans in institutional portfolios pdf

The role of floating-rate bank loans in institutional portfolios pdf

Ngân hàng - Tín dụng

... spread is the market-determined spread paid to the investor for taking on the credit risk (historically the normal range has been 3%–8%, depending on the riskiness of a loan) The credit spread reflects ... in the last several years Therefore, different technical factors are introduced, such as mutual fund flows, in the bank loan market today Exhibit shows monthly historic returns of the index The ... movements The default rate is the default rate of a bank loan portfolio (historically, 2%–3%), and the recovery rate is the amount of principal recovered in the event of default (historically,...
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Báo cáo khoa học: The role of residues R97 and Y331 in modulating the pH optimum of an insect b-glycosidase of family 1 pdf

Báo cáo khoa học: The role of residues R97 and Y331 in modulating the pH optimum of an insect b-glycosidase of family 1 pdf

Báo cáo khoa học

... chain of F331 Thus, the increment in the pKa of E399, in addition to it being closer to E187, may have resulted in a large shift in the pKa of E187 Changes in the dielectric constant due to F331 ... elements in the determination of Sfbgly50 pH optimum The role of arginine in the modulation of the b-glycosidase pH optimum had not been studied before The substitution of Y298 for phenylalanine in ... of E187 remained the same, but the pKa of E399 clearly increased Actually, the substitution of R97 by methionine or lysine resulted in the same increment in the pKa of E399 (Table 2) Therefore,...
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Báo cáo khoa học: The role of Ureaplasma nucleoside monophosphate kinases in the synthesis of nucleoside triphosphates potx

Báo cáo khoa học: The role of Ureaplasma nucleoside monophosphate kinases in the synthesis of nucleoside triphosphates potx

Báo cáo khoa học

... 6-His tag and a thrombin cleavage site were introduced to the N-terminus of the recombinant proteins Tryptophans, coded by UGA codons in UMPK and AMPK, were mutated to UGG using the sitedirected mutagenesis ... present, the rate-limiting step in the synthesis of dNTPs ⁄ NTPs is not the conversion of (d)NDPs to (d)NTPs, as the catalytic efficiency of NDK is high [7–9] The regulatory mechanism in dNTPs ... thymidylate kinase, cytidylate kinase, and uridylate kinase, were cloned and expressed in E coli The recombinant enzymes were affinity purified and their role in dNTP and NTP synthesis was investigated...
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