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Báo cáo khoa học: A novel factor XI missense mutation (Val371Ile) in the activation loop is responsible for a case of mild type II factor XI deficiency doc
... the value of the asymptotic parameter V¥ corresponds to the velocity of the substrate hydrolysis by the FXIa concentration equal to the nominal concentration of zymogen FXI present in solution, ... resulting in a small interference with the binding of the activator to the FXI zymogen There are some examples of inherited coagulation disorders in which one of the peptide linkages required for the ... following the cleavage site of FXI (P2¢ position, according to the convention of numbering position around the scissile bond), thus is part of the activation loop One hundred haploid genomes from...
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Báo cáo hóa học: "The density of macrophages in the invasive front is inversely correlated to liver metastasis in colon cancer" docx
... resection of hepatic lesions None of the patients had undergone either chemotherapy or radiotherapy before the collection of the samples The histopathologic characteristics of the colon carcinoma tissue ... reason that macrophage infiltration improves the prognosis of patients with colon cancer The molecular mechanisms underlying hepatic metastasis of colon cancers is poorly understood Traditional ... classification was used for pathologic grading The study was conducted in accordance with the Helsinki Declaration and approved by the Ethics Committee of our institution Patients were informed of the investigational...
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Tài liệu IN THE HEART OF AFRICA pptx
... where the pilot lay in his blood; and still the mocking spirits of the desert, the afreets of the mirage, led them on, and the hike glistening in the sunshine tempted them to bathe in its cool ... of the plunder, in excess of the amount to be delivered to their employer; he also must have his plunder before he parts with the bags of dollars to the governor of the province Thus the unfortunate ... of the river are hollowed out by the force of the stream to a depth of twenty or thirty feet below the level of the bed Accordingly these holes become reservoirs of water when the river is otherwise...
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Tài liệu Báo cáo khoa học: A novel type of highly negatively charged lipooligosaccharide from Pseudomonas stutzeri OX1 possessing two 4,6-O-(1-carboxy)-ethylidene residues in the outer core region ppt
... attached to O- 7 of the heptose moiety D The GalN C was attached to the O- 3 position of this last heptose as shown by the NOE effect between the anomeric proton of GalN and H-3 of D GalN is the ... role in the interaction of the microorganism with the environment [12,13] In this paper, the structural characterization of the carbohydrate backbone of the rough form LPS of P stutzeri OX1 is ... that the fifth phosphate group is present as pyrophosphate on heptose U In conclusion, information derived from both acid and alkaline hydrolysis leads to the proposal of the following structure of...
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Báo cáo khoa học: NMR and MS evidences for a random assembled O-specific chain structure in the LPS of the bacterium Xanthomonas campestris pv. Vitians A case of unsystematic biosynthetic polymerization potx
... position of the nodal a-Rha This was deduced by an interresidual nOe between the anomeric proton of the a-Fuc3NAc and the H1 and H2 of the a-Rha and by the cross peak in the gHSQCNOESY of the same ... a-Rha to the anomeric proton of the substituting residue The residue to which the a-Rha was linked was recognized examining the inter residue nOe of its anomeric proton to H3 of the substituted ... B) Figure 8A shows the PSD spectrum from analysis of the ion of m/z 853.4 The m/z of the precursor ion corresponds to the sodium adduct ion of Rha3(Fuc3NAc)2 The spectrum is dominated by B- and...
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The French in the Heart of America doc
... shore of Ontario they coast, stopping on the way to visit the Senecas, La Salle, at least, hoping to find there a guide to the headwaters of what is now known as the Ohio River Disappointed, he ... loyalty of his Tonty in the heart of the wilderness Still undismayed, he turns his hand to the giant task again, only to find when he reaches the Illinois a dread foreboding of the crowning disaster ... impulses of the Wisconsin or of the Ohio, and now of the richer-silted blood of the Rockies (as Mr Raymond S Spears, writing of the river, has graphically described), [Footnote: "The Moods of the Mississippi,"...
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Báo cáo y học: "Erythropoietin in the critically ill – is it more than just blood" ppt
... [10,11] The history of clinical trials in sepsis should stand as an example of the challenges in performing such studies [12] The recent appreciation of the importance of the nonhematologic activities ... activities of EPO is providing exciting new avenues for study Despite the inherent difficulties in performing these studies in the critically ill, the potential for EPO to be of benefit in the critically ... Care October 2004 Vol No Corwin difficult to determine More importantly, the pathophysiology of tissue injury in the critically ill can be quite complex, involving many interacting factors [10,11]...
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Báo cáo y học: "Atrial fibrillation is not just an artefact in the ICU" doc
... Meierhenrich and colleagues contributes to our better understanding of the mechanisms contributing to AF in the ICU Nevertheless, the impact of such findings remains elusive from a therapeutic point ... Cardiology/American Heart Association Task Force on Practice Guidelines and the European Society of Cardiology Committee for Practice Guidelines (Writing Committee to Revise the 2001 Guidelines for the Management ... review of the published data J Am Coll Cardiol 2007, 50:2021-2028 Brathwaite D, Weissman C: The new onset of atrial arrhythmias following major noncardiothoracic surgery is associated with increased...
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Thông khí nhân tạo và hô hấp ở trẻ em MECHANICAL VENTILATION IN THE NEONATE
... although they will eventually rise and the reduced chest vibration is easy to miss Chest X-ray is currently the best diagnostic tool for this Point D in figure: Optimal inflation weaning: The goal ... goal should be to move the baby’s lungs from point B to point D avoiding point C Having achieved optimal lung inflation by slowly reducing MAP, it should be possible to maintain the same lung inflation ... clearing of the lung fields as atelectasis resolves Once the baby is stable in an FiO2 < 30%, the MAP should be cautiously reduced in cmH 2O increments as allowed by the oxygenation (to get to point...
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Nathaniel philbrick in the heart of the sea the t sex (v5 0)
... the howling forces of the wind Pollard took the opportunity to pull the crew back together “[T ]he cool and undismayed countenance of the captain,” Nickerson remembered, “soon brought all to their ... to point the ship into the oncoming wind, to relieve the pressure on the sails by letting them luff, or to turn almost 180 degrees in the opposite direction, away from the wind, and let the storm ... wonder while in sessions On all the various forms and fashions Yet another gathering spot for amorous young people was the ridge of hills behind the town where the four windmills stood Here couples...
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Tài liệu Báo cáo khoa học: Interruption of triacylglycerol synthesis in the endoplasmic reticulum is the initiating event for saturated fatty acid-induced lipotoxicity in liver cells pdf
... expression of proinflammatory cytokines, inhibition of insulin signaling, induction of endoplasmic reticulum (ER) stress, and promotion of cell death, mainly by apoptosis [6–12] On the other hand, ... protein (CHOP) proteins downstream of eIF2a were observed (Fig 4A), indicating the initiation of ER stress-induced apoptosis Oleate was unable to induce the expression of the proapoptotic protein ... increased incorporation of palmitate (16:0) into the TAG pool only in the presence of oleate [18] The above results raise two main questions: (a) what is the cause of TAG synthesis inhibition, and...
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Tài liệu Báo cáo khoa học: Moult cycle-related changes in biological activity of moult-inhibiting hormone (MIH) and crustacean hyperglycaemic hormone (CHH) in the crab, Carcinus maenas From target to transcript ppt
... major secretory products of the YO, ecdysone and 25-deoxyecysone Inhibition of 3-dehydroecdysone synthesis was not measured, but this is a minor secretory product of Carcinus YO [11] Loss of ... resumption of competence of the YO at stage C1 Thus, it seems that selectivity, with regard to YO responses to MIH or CHH during the moult cycle is not at the receptor level In view of these observations, ... content of the culture medium However, to measure inhibition of ecdysone and 25-deoxyecdysone biosynthesis (these ecdysteroids are the major ones secreted by Carcinus YO in vitro [11]), pooled samples...
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Global Environmental Health in the 21st Century: From Governmental Regulation to Corporate Social Responsibility ppt
... common denominator—it doesn’t differentiate between the types of exposure, the quantities of exposures, or the scenarios for exposures In addition to the factor of risk, it also includes whether ... Union has more than 450 million people in an area half the size of the United States REACH is a response to the opinion in the EU that the burden of proof of what chemicals are not safe is no longer ... of eminent members of appropriate professions in the examination of policy matters pertaining to the health of the public The Institute acts under the r esponsibility given to the National...
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No Safer Place in the World for Your Money - How to Make Sure All Your Deposits Are Protected by FDIC Insurance docx
... two-page overview of the information most people want to know about their FDIC coverage The other is “Your Insured Deposits,” a handy guide intended to provide basic information on the rules for the ... www.fdic.gov/deposit/ deposits To order the video on DVD or CD-ROM, click on the link to the online order form The video also can be downloaded for use on a portable audio (MP3) player by clicking on the link ... access to accounts on the next business day by arranging with a healthy institution to assume the insured deposits The account owners can then decide whether to remain as customers of the other...
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CREATIVE ACCRUAL ACCOUNTING IN THE PUBLIC SECTOR: ‘MILKING’WATER UTILITIES TO BALANCE MUNICIPAL BUDGETS AND ACCOUNTS pot
... utilities The purpose of this paper is to explore and analyse the effects of the two aforementioned types of NPM reforms: accountingization, i.e the application of business-sector accounting models in ... the City) The fourth section analyses the sale, its motivations and consequences in the light of the theoretical framework provided, and the final section sets out the authors’ conclusions THEORETICAL ... from the businesssector model in several ways, an important one of which is a terminology tailored for the local government sector only This concerns, for instance, the terms describing the intermediate...
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Blackwell Publishing Ltd Gregariousness and protandry promote reproductive insurance in the invasive gastropod Crepidula fornicata: evidence from assignment of larval paternity potx
... percentage of larvae sired (B) Position of the father is given relative to the position of the male (position 0), which is the closest to the mother at the time of the collection within the main stack ... by the assigned fathers (A1) Position of the father is given relative to the position of the mother (0 is the mother) ′Side position′ is used for single individuals recorded in a side position ... transition), including the mother, to take into account the possibility for self-fertilization (as hypothesized by Orton 1950) The proportion of multiply sired broods was compared between populations...
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Báo cáo khoa học: Liver receptor homolog-1 localization in the nuclear body is regulated by sumoylation and cAMP signaling in rat granulosa cells docx
... observed in present study Some other factors may also enhance SUMO modification of LRH-1 in vivo, such as E3 proteins, or promote the targeting of sumoylated LRH-1 into nuclear bodies The expression of ... steroid production by gonadotrophins is mainly through the activation of the cAMP ⁄ protein kinase A pathway LRH-1 is an important regulator of ovarian steroidogenesis The release of LRH-1 from nuclear ... speckles is associated with sumoylation, we therefore determine whether cAMP signaling affects the SUMO modification pathway We used RT-PCR to study the effects of forskolin on the expression of genes...
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peachpit press ios 5 in the enterprise, a hands-on guide to managing iphones and ipads (2012)
... you can download it by going to the Provisioning section of the provisioning portal, selecting the Distribution tab, and clicking Download When the file is downloaded, drag it to the top pane of ... profile (a mobileprovision file) into the top pane of the Provisioning Profile section; or, click the Add button, navigate to the profile, and click Open to add it to the iPCU After the profile is installed, ... neat or cool (Yes, neat/cool counts in IT You’d be amazed.) XIV iOS IN THE ENTERPRISE WHAT THIS BOOK IS NOT If you’re looking for a cookbook of how-tos, I will tell you now, this is not the book...
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kolomoki settlement ceremony and status in the deep south a d 350 to 750 sep 2003
... Roughly km to the northwest of the site, Little Kolomoki Creek joins the North Prong of Kolomoki Creek to form Kolomoki Creek proper Kolomoki Creek ®ows into the Chattahoochee River approximately ... more thorough review of previous research at Kolomoki and then examine the archaeology of the major earthworks Also presented is an evaluation of previous work in the off-mound portions of the ... mentioned in the text 1.2 The Kolomoki site 2.1 Location of Kolomoki with respect to major rivers 2.2 Location of Kolomoki with respect to major physiographic divisions of the Coastal Plain 33...
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