myocardial cell based regeneration in heart failure
Báo cáo y học: "Different effect of exercise on left ventricular diastolic time and interventricular dyssynchrony in heart failure patients with and without left bundle branch block"
... lack of increase in LV dyssynchrony during dobutamine stress in patients with wide QRS duration (20) In contrast, Kurita et al reported on an increased mechanical dyssynchrony during pacing–induced ... is a principal determinant of myocardial perfusion and of the blood volume received during diastole Since both, a reduced myocardial perfusion reserve and diastolic heart failure, are an integral ... pacing–induced tachycardia in patients with normal QRS duration (21) A remarkable increase in intra-LV dyssynchrony was also demonstrated during pharmacological stress in systolic heart failure patients...
- 8
- 868
- 1
Báo cáo y học: " Major biological obstacles for persistent cell-based regeneration of articular cartilage" pps
... Latex beads as probes of cell surface-extracellular matrix interactions during chondrogenesis: evidence for a role for amino-terminal heparin-binding domain of fibronectin Dev Biol 1989, 136:8796 ... fibronectin, laminin and related integrin receptors during the early chondrocyte differentiation J Cell Sci 1997, 110: 2261-2270 DeLise AM, Fischer L, Tuan RS: Cellular interactions and signaling in ... diseases such as OA or RA can cause joint inflammation of varying intensities The cytokines involved, including IL-1 and TNF-α, have direct and indirect pro-inflammatory effects to regulate the...
- 15
- 240
- 0
THE ROLE OF SURGERY IN HEART FAILURE - part 2 pps
... who have heart failure worldwide Heart failure is primarily a disease of the elderly, and the prevalence of chronic heart failure increases with advancing age Currently, chronic heart failure ... remaining 50% to 70% of patients present with systolic heart failure that is clinically indistinguishable from diastolic heart failure It is important to identify patients who have systolic heart ... chronic shortage of donor hearts Currently, the mainstay of heart failure treatment is pharmacologic and includes angiotensin converting enzyme inhibitors, angiotensin receptor blockers, b-adrenergic...
- 2
- 302
- 0
THE ROLE OF SURGERY IN HEART FAILURE - part 3 pptx
... Heart Failure Clin (2007) 139–157 Surgery for Heart Failure: Now Something for Everyone? Stephen Westaby, MS, PhD, FRCS* Oxford Heart Centre, John Radcliffe Hospital, Headington Oxford, ... better understanding of the anatomy and pathophysiology of heart failure The failing heart beats at more than 120,000 beats per day, pumping more than 6,000 L of blood against an increased systemic ... This procedure was the landmark beginning of cardiac pacing (Fig 1) For the past 50 years cardiac surgery has been in a continuous state of flux In congenital heart disease palliative techniques...
- 2
- 282
- 0
THE ROLE OF SURGERY IN HEART FAILURE - part 4 ppsx
... transvalvular gradient [4] Intraoperative myocardial injury remains prevalent in the increasingly elderly surgical population because tolerance to ischemia is reduced in aged myocardium [5] Patients ... coronary bypass and unstable angina to a glycoprotein IIb/IIIa inhibitor or placebo, the 7-day mortality or myocardial infarction rate was 22.3% in almost 700 patients in the control arm [2] A collective ... improve survival in the postcardiotomy setting Mechanisms of postcardiotomy myocardial dysfunction Efforts to improve surgical results in patients who have heart failure depend on myocardial protection...
- 2
- 289
- 0
THE ROLE OF SURGERY IN HEART FAILURE - part 6 doc
... acutely in the minutes following AMI, prolonged systolic and diastolic dysfunction occurs [7] Cell death proceeds by way of apoptosis (programmed cell death) or oncosis (cell swelling), depending ... their rationale in the setting of life-threatening AMI and acute on chronic * Corresponding author New York Presbyterian Hospital, Milstein Hospital Building, Room 7-435, 177 Fort Washington Avenue, ... Heart Failure Clin (2007) 181–210 Surgery for Myocardial Salvage in Acute Myocardial Infarction and Acute Coronary Syndromes George M Comas,...
- 2
- 244
- 0
THE ROLE OF SURGERY IN HEART FAILURE - part 8 pdf
... Heart Failure Clin (2007) 211–228 Revascularization in Heart Failure: Coronary Bypass or Percutaneous Coronary Intervention? Sorin V Pusca, MD, John D Puskas, MD* ... compares it with percutaneous coronary interventions (PCI) in this setting Alternative modalities for the surgical treatment of ischemic heart failure, such as heart transplantation, surgical ventricular ... revascularization for acute myocardial infarction [8] Its usefulness in selecting patients who have chronic disease for revascularization may not be as great, however As an indicator of depressed...
- 2
- 273
- 0
THE ROLE OF SURGERY IN HEART FAILURE - part 9 potx
... b Ischemic heart disease is the leading cause of heart failure in North America, accounting for approximately two thirds of heart failure cases [1] Patients who have ischemic heart failure suffer ... The increase in tension plays a key role in activating complex neurohormonal mechanisms, including an increase in angiotensin II, collagen deposition, and degradation through metalloproteinase-1 ... doi:10.1016/j.hfc.2007.05.003 heartfailure.theclinics.com Heart Failure Clin (2007) 237–243 Left Ventricular Restoration: How Important is the Surgical Treatment of Ischemic Heart Failure Trial? Lorenzo...
- 3
- 265
- 0
THE ROLE OF SURGERY IN HEART FAILURE - PART 2 pdf
... individual patient basis [13] Indeed, it may not be 1551-7136/07/$ - see front matter Ó 2007 Elsevier Inc All rights reserved doi:10.1016/j.hfc.2007.05.005 heartfailure.theclinics.com Heart Failure ... obtain the first results of trials in 2007 Revascularization is not discussed further in this manuscript The initial enthusiasm for skeletal myoblast and stem cell transplantation into the failing ... erythropoietin-stimulating peptides when not due to specific haematinic deficiency may also improve symptoms, although the data are not robust [5] Withdrawal of nonsteroidal anti -in ammatory drugs, including...
- 3
- 273
- 0
THE ROLE OF SURGERY IN HEART FAILURE - PART 4 ppt
... allows the heart a period of relative rest in which functional improvement may be achieved by interrupting the vicious circle of increasing wall tension and functional impairment The hearts of ... Heart Failure Clin (2007) 299–315 Patients who Have Dilated Cardiomyopathy Must Have a Trial of Bridge to Recovery (Pro) Johannes Mueller, MDa,*, Gerd Wallukat, PhDb b a Berlin Heart, Berlin, ... devices with biventricular pacing * Corresponding author Berlin Heart, Wiesenweg 10, 12247 Berlin, Germany E-mail address: johannes.mueller@berlinheart.de (J Mueller) capability postpones the...
- 2
- 222
- 0
THE ROLE OF SURGERY IN HEART FAILURE - PART 6 pdf
... efficacy remains somewhat uncertain [2,3] 1551-7136/07/$ - see front matter Ó 2007 Elsevier Inc All rights reserved doi:10.1016/j.hfc.2007.05.007 heartfailure.theclinics.com Heart Failure Clin (2007) ... multidisciplinary teams; new pharmacologic compounds, including angiotensin-converting enzyme (ACE) inhibitors, angiotensin-receptor blockers, spironolactone and beta-blockers; novel devices, including ... have severe heart failure has increased in complexity, requiring greater skills and finer judgment from the physician and surgeon New drugs have emerged, the expertise of physicians in using these...
- 3
- 266
- 0
THE ROLE OF SURGERY IN HEART FAILURE - PART 9 docx
... dilated chamber and pumped in a pulsatile manner to the ascending aorta at a rate of between and 10 L/min In patients dying of cardiogenic shock these devices sustain life until a donor organ ... attenuate the cytokine and humeral responses to heart failure [7] Transplant outcomes are improved because terminally ill patients are in better condition to survive major surgery [8] In turn comes ... and infrequent intervention In the study by Sharples and colleagues [11] evaluating the ventricular assist device program in the United 1551-7136/07/$ - see front matter Ó 2007 Elsevier Inc All...
- 2
- 222
- 0
THE ROLE OF SURGERY IN HEART FAILURE - PART 10 potx
... surgery, in advanced heart failure, 328 Coronary interventions, percutaneous, in advanced heart failure, 327–328 D Defibrillator, cardiac, automatic implantable, in advanced heart failure, 326–327 in atable, ... disease in, 295 Aortic valve replacement, in aortic stenosis, 294–295 return of congestive heart failure following, 295 Aortic valve surgery, decision for, in aortic regurgitation, 293 in advanced heart ... 369–375 mechanical, in advanced heart failure, 331, 332 Coagulopathies, destination mechanical circulatory support devices and, 331, 353 Congestive heart failure See Heart failure, congestive...
- 2
- 192
- 0
Báo cáo hóa học: "Hybrid approach of ventricular assist device and autologous bone marrow stem cells implantation in end-stage ischemic heart failure enhances myocardial reperfusion" doc
... Medicine 2011, 9:12 http://www.translational-medicine.com/content/9/1/12 Figure Intraoperative view showing clinical application of stem cells into the failing heart with multiple targeted injections ... improved intrinsic myocardial contractile properties [12] Regarding ICM, LVAD support cannot lead to repopulation of the infarcted tissue with contracting cardiomyocytes This fact could explain the inability ... (BM) stem cells differentiated in a mouse myocardial infarction model into cardiomyocytes that reduced infarct size and improved myocardial function [15], Murry C, et al showed that the injected...
- 5
- 411
- 0
Sudden Death in Patients with Myocardial Infarction and Left Ventricular Dysfunction, Heart Failure, or Both pdf
... myocardial infarction Table Event Rate and Cumulative Incidence of Events during Follow-up.* Time after Myocardial Infarction No at Risk at Beginning of Interval No Who Died of Any Cause during ... approach to minimizing the risk of sudden death after myocardial infarction, the recently reported DINAMIT showed no benefit of implanting an ICD to 40 days after myocardial infarction in patients ... reduced heart- rate variability.10 Indeed, in that trial, a decrease in the rate of death from arrhythmia was offset by an increase in the rate of death from other causes.19 The DINAMIT findings...
- 18
- 362
- 0
Báo cáo y học: "Replacement of cisplatin with nedaplatin in a definitive 5-fluorouracil/ cisplatin-based chemoradiotherapy in Japanese patients with esophageal squamous cell carcinoma"
... nephrotoxicity and gastrointestinal toxicity than CDDP [14] In phase II clinical studies, NDP was found to be highly effective against solid tumors, including non-small cell lung cancer, small cell lung cancer, ... toxicity in the treatment of ESCC [16] In this study, the effects of replacing CDDP with NDP on the pharmacokinetics of 5-FU 306 were investigated in ESCC patients treated with a definitive 5-FU/CDDP -based ... cancer, and treatments include surgical procedures, radiation, chemotherapy, and combinations thereof [10] In patients with localized squamous cell carcinoma, a definitive 5-FU/CDDP -based CRT is one...
- 7
- 531
- 0
Báo cáo khoa học: Bridging the gap between in silico and cell-based analysis of the nuclear factor-jB signaling pathway by in vitro studies of IKK2 ppt
... future inhibitors designed for this NF-jB signaling pathway should be tested not just in vitro and cell based but also simulated in silico Combining this method of analysis (in vitro, cell- based ... nuclear NF-jB in single cell studies In our cell- based experiments, a population of 10 000 A549 cells was observed to undergo similar oscillatory behavior to that discovered in single cells in terms ... lL; prewarmed in a water bath at 37 C) was dispensed into each well and incubated for 15 (prewarming xative is critical to maintaining cell integrity) After 15 min, the plates were inverted to...
- 13
- 475
- 0
Tìm thêm: xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ rôto dây quấn các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25