... and EBC pH have been proposed as procedures for the evaluation ofairway inflammation [13,14], our results might be interpreted as an additional argument for the absence of effect of SIT on airway ... Respiratory Society: ATS/ERS recommendations for standardized procedures for the online and offline measurementofexhaled lower respiratory nitric oxide and nasal nitric oxide Am J Respir Crit Care ... the end of collection, the sample was carefully removed from the collection system and EBC pH was determined in a 0.2 ml aliquot immediately after collection Measurementof EBC pH The pHof the...
... technicians, who were not aware of the EBC pH measurements, in order to ensure consistency of results ExhaledBreathcondensate collection andpHmeasurementExhaledbreathcondensate (EBC) was collected ... Identification of acid reflux cough using serial assays ofexhaledbreathcondensatepH Cough 2006, 2:3 doi:10.1186/1465-9921-12-67 Cite this article as: Papaioannou et al.: ExhaledbreathcondensatepH ... participated in its design and coordination AIP, MM, KKon and PB performed the recruitment of patients and study measurements KK, AIP and MM performed the statistical analysis AIP and KK drafted the...
... repeatability ofexhaledbreathcondensatepH in asthma Respir Med 2008, 102:377-381 Kullmann T, Barta I, Lazar Z, Szili B, Barat E, Valyon M, Kollai M, Horvath I: ExhaledbreathcondensatepH standardised ... Endogenous airway acidification Implicationsfor asthma pathophysiology Am J Respir Crit Care Med 2000, 161:694-699 Borrill Z, Starkey C, Vestbo J, Singh D: Reproducibility ofexhaledbreathcondensate ... obtain a wide range ofpH values and to address methodological questions in relevant patient groups Our results on the performance of the RTube and ECoScreen forpH analysis of EBC in healthy controls...
... subjects 100% Positive EBC pH Profile Negative EBC pH Profile Figure Multi-sample EBC pH profiles of controls and patients Multi-sample EBC pH profiles of controls and patients Chronic cough ... Repeated exhaledbreathcondensatepH (after gas standardization) before and after pharyngeal challenge by means of an acidic drink (Figure 1A) and after a water control (Figure 1B) EBC pH is transiently ... EBC pH 7.5 6.5 5.5 4.5 3.5 Figure acidic drink (Figure 1A) pharyngeal challenge by means of an zation) before and after and after a water control standardiRepeated exhaledbreathcondensate pH...
... Validation of leukotriene B4 measurements in exhaledbreathcondensate Inflamm Res 2003, 52:69-73 Mutlu GM, Garey KW, Robbins RA, Danziger LH, Rubinstein I: Collection and analysis ofexhaledbreathcondensate ... for each compound are listed in Table and were performed with continuous flow injections of standard solutions of all analytes with a Page of (page number not for citation purposes) Journal of ... two chromatographic processes: on one hand reversed phase interactions for the retention of unpolar and middle polar compounds, and on the other hand size exclusion chromatography to avoid macromolecules...
... 8.4 8.3 pH 8.2 8.1 8.0 7.9 Pre Post omeprazole (40 mg/day x 14d) Figure and after in exhaled treatment pH valuesomeprazolebreath condensate in patients before pH values in exhaledbreathcondensate ... changes in pHof the exhaledbreathcondensate We conclude that these measurements not reflect the clinical response Additionally, omeprazole does not change the pHofexhaledbreath condensate, ... significance of acid pH in the pathogenesis of GOR-associated cough, we measured pHofexhaledbreathcondensate in patients with chronic cough associated with abnormal lower oesophageal pH We determined...
... Quality of Life for Eating Disorders-Short Form (HeRQoLED-S) Item content was examined for the misfitting items before removal from the scale Two of the authors of the present study (JAP and CLH) ... independent domain and the symptoms domain is a list of symptoms rather than a proper measurement scale A second-order CFA composed of a measurement model and a structural model was performed We hypothesized ... 41), except for two items ("Do you have to stop performing some tasks as a result of your physical problem?” and “Do you find it difficult to maintain the attention as a result of your physical...
... survivors, and to reveal implicationsof QOL measurementfor Chinese cervical cancer survivors Framework of quality of life Quality of life is dynamic and changes over time [12] Traditional models of ... Conception, development, and validation of instruments for quality of life assessment: An overview Statistical Methods for Quality of Life Studies: Design, Measurementand Analysis Boston: Kluwer ... common types of reliability Zeng et al Health and Quality of Life Outcomes 2010, 8:30 http://www.hqlo.com/content/8/1/30 Page of Figure Flowchart of search and selection process reported for QOL questionnaires...
... release of progenitors of eosinophils from the bone marrow, and, together with IL-5, increases the count of mature forms in peripheral blood The consequence of these processes is peripheral and tissue ... questions concerning the lack of standardization for both the collection and analysis of EBC, the repeatability of measurements, and the effect of many factors on concentrations of EBC markers, are still ... perils ofexhaledbreath condensates Am J Physiol Lung Cell Mol Physiol 2004, 287:1073-80 Ko FWS, Lau CYK, Leung TF, et al: Exhaledbreathcondensate levels of eotaxin and macrophage-derived chemokine...
... leukotrienes, prostaglandins, adenosine, and 8-isoprostane Concentrations of these mediators have proved to be a useful noninvasive method for the assessment andmonitoringofairway inflammation ... performed to clarify the possible role of ET1 in the pathogenesis of EIB, particular in the inflammatory basis of this condition and the remodeling of the airways We show that, as a result of ... rate to 85% of the maximum predicted for the age of each patient [15] Basic spirometric parameters were recorded before, and immediately after, the exercise test, and 1, 5, 10, 15, 20, and 60 minutes...
... J: Measurementofexhaledbreathcondensate pH: implicationsforpathophysiologyandmonitoringof inflammatory airwaydiseases In New Perspectives in Monitoring Lung Inflammation Analysis ofExhaled ... inhalation The pHof the airway lining fluid is the result of a balance between different buffer systems and the production and release of acids and bases in the airways [1] In a healthy airway, several ... P, van Rensen EL, Rubinstein I, Silkoff P, ATS/ERS Task Force on ExhaledBreath Condensate, et al.: Exhaledbreath condensate: methodological recommendations and unresolved questions Eur Respir...
... Rural and Micro Finance Regulation in Ghana: Implicationsfor Development and Performance of the Industry By William F Steel & David O Andah June 2003 Foreword his country study is one of three ... Annex 1: Microfinance Legislation in Uganda and Ethiopia 40 Annex 2: Evolution of Legal Framework for RMFIs 43 Annex 3: Summary of Laws and Regulations for RMFIs and Businesses ... Ghana: Implicationsfor Development and Performance of the Industry William F Steel and David O Andah I Background A Introduction The purpose of this paper is to assess how the policy, le gal and...
... Qc, Canada Full list of author information is available at the end of the article thymic and peripheral CD4+ T cells in humans and mice, and arise during normal thymic lymphocyte development T ... background of the host, microflora and target tissue As such, Treg depletion, or alterations of the foxp3 gene, as seen in Scurfy mice or IPEX patients, results in a loss of Treg cells, and catastrophic ... required for the maintenance of the expression of the genes involved in the regulation of cell growth and metabolism [22] Hence, IL-2 has a critical role in the homeostasis and competitive fitness of...
... internalization of CTLA-4 and tight regulation of surface CTLA-4 CTLA-4 is also able to bind the serine/threonine phosphatase protein phosphatase 2A (PP2A) PP2A seems to act as a negative regulator of CTLA-4 ... pattern formation cannot occur by the interaction of CD86 with CTLA-4 Activation of CTLA-4 by binding to its ligands leads to the phosphorylation of tyrosine residues in the cytoplasmic tail of CTLA-4 ... the phosphorylation and activation of the kinases Tec and Itk [36,37] as well as other signalling molecules such as the guanine-nucleotide-exchange factor Vav-1 or phospholipase Cγ1 [38] All of...
... negative and positive selection of B and T cells), andfor lymphoid organ morphogenesis [21,22] Defects in NF-κB function or control permit the survival and release into the periphery of autoreactive ... the periphery (draining lymph nodes and spleen) Several authors have shown that NF-κB is required for the development of mTECs and organization of the thymic stroma, and the development and differentiation ... activation regulate survival and activation of T and B lymphocytes at their sites of development in thymus, bone marrow and spleen, and in the periphery In normal conditions of health the immune system...
... to the Guinean forests of West Africa The fleshy arils of the ripened fruits are edible Seeds and capsules of the fruits are used for soap-making andfor fishing, and all parts of the tree have ... different phytogeographic zones of Benin Each phytogeographic zone hosts various ethnic groups and members of the same ethnic group are sometimes dispersed across different phytogeographic zones ... analyses of the physical composition of arils from Toukountouna (North-West Benin) have shown that it includes 46% of oil, 47% of fibres and 3% of proteins [10] The food value of 100 g of raw arils...
... consists of 28 species of reptiles and 17 species of amphibians [42] that exhibit a wide variety of shapes, colors, behaviors and lifestyles, The distribution of Iberian herpetofauna is profoundly ... source of southern Portuguese gecko folklore and TEK, as well as their possible impact on future scientific studies of geckos and their conservation Page of Natural and Cultural History of Geckos and ... TEK and folklore play a beneficial role in nature conservation, such as the importance of taboos and social norms for the conservation of species and habitats [5-9], the importance of folklore and...
... step of at 95°C, 40 cycles of 95°C for 30 s, 52°C for 30 s and 72°C for 60 s, and then cycle of 72°C for PCR products were cloned into pGEM Easy vector (Promega) and sequenced Sequencing of four ... each of dATP, dCTP, dGTP, dTTP and μM SYTO9 fluorescent dye (Invitrogen) PCR cycling conditions were 94°C for min, followed by 40 cycles of 94°C for 15 s, 60°C for 30 s and 72°C for 30 s For MtSERK3 ... 256-fold for the forward primers and 1024-fold for the reverse primers, with a predicted amplicon size of around 446 bp Degenerate PCR was performed on cDNA and genomic DNA using a μM concentration of...
... claims of MLV-related viruses in prostate cancer and CFS patients Future assessments of the prevalence of XMRV should include more rigorous PCR and phylogenetic tests to exclude the possibility of ... AI060466 and R37 AI47734 I thank Drs Geoff Gottlieb, Jim Mullins, John Mittler and Mary Campbell (UW) and Dr Dusty Miller (Fred Hutchinson Cancer Research Institute) for helpful discussions of XMRV ... Contamination of clinical specimens with MLV-encoding nucleic acids: implicationsfor XMRV and other candidate human retroviruses Retrovirology 2010 7:112 Submit your next manuscript to BioMed Central and...
... analyses This work was performed as a part of the Russian in Flux-research programme of the Academy of Finland and was financially supported by the Academy of Finland The office space provided by ... correction) The bias for rW for UN pairs was downwards, while that for rW and rQG in the category of PO was upwards (Additional file 3) The performance of rK was very similar to that of rW (results ... prior for the distribution of offspring between males and females was set to be gamma (1, 2) Influence of the six Yakutian cryobank bulls on the genetic variability of the reference population and...