lipoproteins role in health and diseases
Lipoproteins – Role in Health and Diseases by Saša Frank and Gerhard Kostner doc
... concentrations 30 Lipoproteins – Role in Health and Diseases 3.2.1 Dyslipidemia and CVD in CKD Forty years ago, Lindner and colleagues described in their seminal report the excessive risk of CVD in HD patients ... lipoprotein structure, the assembly and kinetics of apoB containing lipoproteins, and the role of Lp(a) in kidney patients Section reviews clinical chemical methods for diagnosing patients at increased ... the protein chain According to this model, epitopes in the LDL receptor binding domain are located on one side of LDL, whereas epitopes located in the N-terminal and Cterminal domains are in close...
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Immunosuppression – Role in Health and Diseases Edited by Suman Kapur and Maristela Barbosa Portela ppt
... – Role in Health and Diseases inflammatory genes during ET are also available For example, binding of high-mobility group box proteins (HMGB1) and histone H1 linker at the promoters of TNFα and ... inflammatory molecules, such as chemokines and chemokine receptors, in leukocytes Chemokines induce cellular migration and are crucial players in initiating both innate and adaptive immune response (Figure ... Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF J Clin Invest., 101, 4,...
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IMMUNOSUPPRESSION – ROLE IN HEALTH AND DISEASES pdf
... – Role in Health and Diseases inflammatory genes during ET are also available For example, binding of high-mobility group box proteins (HMGB1) and histone H1 linker at the promoters of TNFα and ... inflammatory molecules, such as chemokines and chemokine receptors, in leukocytes Chemokines induce cellular migration and are crucial players in initiating both innate and adaptive immune response (Figure ... Macrophages that have ingested apoptotic cells in vitro inhibit proinflammatory cytokine production through autocrine/paracrine mechanisms involving TGF-beta, PGE2, and PAF J Clin Invest., 101, 4,...
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PHYTOCHEMICALS – A GLOBAL PERSPECTIVE OF THEIR ROLE IN NUTRITION AND HEALTH potx
... important alkaloids of plant origin include the addictive stimulants caffeine, nicotine, codeine, atropine, morphine, ergotamine, cocaine, nicotine and ephedrine (Fig 1) Amino acids act as precursors ... of saponins and these include: steroid saponins and triterpene saponins Saponins are soluble in water and insoluble in ether, and like glycosides on hydrolysis, they give aglycones Saponins are ... hydrolysable tannins include theaflavins (from tea), daidezein, genistein and glycitein (Fig 5) Tanninrich medicinal plants are used as healing agents in a number of diseases In Ayurveda, formulations...
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Báo cáo y học: "Cartilage homeostasis in health and rheumatic diseases" pptx
... chronic inflammation exists, as in RA Conclusions Laboratory investigations in vitro and in vivo regarding the role of the chondrocyte in remodeling the cartilage matrix in the RA and OA joint have ... leptin and other adipokines, such as adiponectin, promotes destructive inflammatory processes [90] Recent studies indicate that resistin plays a role in early stages of trauma-induced OA and in ... protein kinases are involved in these responses, including protein kinase Cζ, which is upregulated in OA cartilage and is required for activation of NF-κB by IL-1 and TNF-α [113] However, it remains...
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research on working conditions, health and diseases of the crew on oceangoing ships of 02 vietnamese ocean shipping companies in 2011-2012
... Reference group: included 300 labours in land, all males and same age with the studied groups who were now working in office, interprises located in Hai Phong and had regular health check in Vietnam ... crews’ health at the specialised health units and health centre of companies 3.4.3.Intervention result by knowledge and practice training of maritime medicine for deck officers 11 Table 3.11 Training ... hours of practice (intensive training for weeks at the Center for Marine Medicine Training subordinate Vietnam National Institute of Maritime Medicine) The students were evaluated in terms of knowledge...
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Tài liệu Differentiation in Health and Physical Education doc
... understanding of a health concept Cubing is a second powerful differentiation tool that provides a new twist on question asking and answering, and works well in a health and physical education setting ... skill e.g., dribbling The first station may involve dribbling in a straight line, the second may involve dribbling between cones and the third may be dribbling against a defender In each station, ... Building a supportive learning classroom begins with the teacher modeling inclusiveness and continues as students work together to achieve their learning goals in a variety of settings Students...
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Tài liệu Báo cáo khoa học: TEC family kinases in health and disease – loss-of-function of BTK and ITK and the gain-of-function fusions ITK–SYK and BTK–SYK pptx
... mutation in the BTK PH domain; arginine 28 is in dark blue, encircled in red Bottom left: SH2 domain Right: kinase domain The mutated residues are indicated in yellow, a-helices are in cyan, ... proline residues are over-represented, presumably secondary to the strong in uence of prolines on peptide folding [21] Thus, proline is a rigid amino acid creating a fixed kink in a protein chain ... player in inflammatory disorders, such as allergic asthma and atopic dermatitis [38,39] In this minireview series, two articles describe the current understanding of ITK’s role in signaling and development...
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Tài liệu Aneuploidy in Health and Disease Edited by Zuzana Storchova doc
... Defects in SAC lead inevitably to high chromosome missegregation levels both in vitro and in vivo and thus to aneuploidy Besides mutations in spindle assembly checkpoint and in mitotic spindle ... spindle assembly checkpoint and often remain uncorrected, resulting in lagging chromosomes and aneuploidy, F syntelic attachments lead to incorrect chromosome segregation, G defects in SAC interfere ... other factors influencing the DNA strand breaks The increasingly detailed map of human DNA will certainly bring new insight into the possible links between DNA secondary structure and sites of...
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New Profit Opportunities in Health and Nutrition to 2009: Changing Consumer Concerns and Market Influencers in Food and Drinks doc
... offered for type diabetes includes taking insulin shots or using an insulin pump, healthy eating, exercising regularly, taking aspirin daily, and controlling blood pressure and cholesterol Type diabetes ... options and marketing streams based on a firm understanding of the major consumer health concerns influencing purchasing decisions and eating habits Identifying the main health- related issues influencing ... are involved in the healthy eating and drinking arena or not In order to produce this report, a number of industry opinion surveys were conducted throughout 2004 to gain access to the highly influential...
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Modern Nutrition in Health and Disease pot
... historically in the opening chapter and considered in separate chapters on individual essential nutrients and in those on taurine, homocysteine, glutamine, arginine, choline, and carnitine There ... approaches Purine and Pyrimidine Biosynthesis The purines (adenine and guanine) and the pyrimidines (uracil and cytosine) are involved in many intracellular reactions when high-energy di- and triphosphates ... organs in the body, but amino acids are consumed in the diet from a variety of protein sources In addition, each amino acid is maintained in part as a free amino acid in solution in blood and inside...
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the auditors’ role in detecting and preventing fraud
... implementation and maintenance of effective internal controls by: - Developing and maintaining an internal control system that is adequate and effective in managing risk - Improving the efficiency and effectiveness ... auditors’ role 2.2.1.2 Internal auditor’s role 2.2.2 Role of auditor in preventing fraud 2.3 The company applies internal control to detecting and preventing fraudulent activities 2.3.1 How internal ... auditors in detecting fraud in financial statements SAS No.99 request independent auditors to obtain information to determine the risk of financial statement fraud, risk assessment by participating in...
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Working with Men in Health and Social Care ppt
... argued for an understanding of masculinity that recognised dominant interpretations and definitions of masculinity as embedded in and sustained by a range of male-dominated institutions such as ... repression of femininity within men (he did recognise its presence within men), but on the resulting balance between a masculine persona and a feminine anima He came to argue that the feminine interior ... and to counselling Our own professional backgrounds are as practitioners in child and family social work, probation and family therapy and also in training practitioners in these fields and in...
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Diffusion and Use of Genomic Innovations in Health and Medicine: Workshop Summary pot
... Diffusion and Use of Genomic Innovations in Health and Medicine: Workshop Summary http://www.nap.edu/catalog/12148.html Diffusion and Use of Genomic Innovations in Health and Medicine workshop ... Diffusion and Use of Genomic Innovations in Health and Medicine: Workshop Summary http://www.nap.edu/catalog/12148.html PLANNING COMMITTEE ON DIFFUSION AND USE OF GENOMIC INNOVATIONS IN HEALTH AND ... public, and the scientific and engineering communities The Council is administered jointly by both Academies and the Institute of Medicine Dr. Ralph J Cicerone and Dr Charles M Vest are chair and...
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Báo cáo khoa học: Regulation of matrix metalloproteinase activity in health and disease pdf
... hemopexin-like domain (C domain) of human gelatinase A (matrix metalloproteinase-2) requires Ca2+ for fibronectin and heparin binding Binding properties of recombinant gelatinase A C domain to ... small integrin-binding ligand N-linked glycoprotein (SIBLING) Individual members of the SIBLING family are known to bind strongly to both pro- and active forms of specific MMPs Bone sialoprotein binds ... osteopontin binds MMP-3 and dentin matrix protein-1 binds MMP-9, all with a : stoichiometric ratio and binding constants in the nanomolar range [26] These SIBLINGs and MMPs are also co-expressed and...
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Interest Rate Policy in Egypt - Its Role in Stabilization and Adjustment pdf
... discounted A Interest Rate and Business Investment The first step in examining how higher interestrates may influence business investmentdecisions and performances is the understandingof firms' ... Government plays a dominantrole in the financialmarket and its interventiinstake many forms, not only in terms of deficit financing,but also equity participationand management control in virtually all ... and domestic demand including public coneumption,the poor performance in export earnings brought about by a combinationof fallingoil prices, rising interestpaymentson external debt, and declining...
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The Neuronal Environment: Brain Homeostasis in Health and Disease pot
... transcription and mRNA binding to cytosolic and polysome proteins in brain and peripheral tissues Brain Res Mol Brain Res 58, 170–177 39 Lauger, P (1991) Na,K-ATPase, in Electrogenic Ion Pumps, Sinauer, ... employed by investigators for the induction of hypoglycemia With the right dose of insulin (50–100 U/kg), hypoglycemic coma ensues within 1–2 h following insulin injection in rats or mice (71) In larger ... the interactions with neurons, and with each other, is crucial in understanding the development and impact of most brain diseases All the authors contributing to The Neuronal Environment: Brain...
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Báo cáo khoa học: Proteoglycans in health and disease: novel regulatory signaling mechanisms evoked by the small leucine-rich proteoglycans ppt
... modulated by lumican-evoked signaling, including vinculin and focal adhesion kinase [82] Lumican alters the relationship between actin filaments and b1 integrin, which in turn would affect focal adhesion ... detail In analogy to decorin, lumican inhibits tumor cell growth in soft agar by increasing the expression of the cyclin-dependent kinase inhibitor p21WAF1 [72] Again, similar to decorin, these ... overlapping with the EGF-binding domain [32] The structural constraints of the EGFR binding region support a stochiometry of : for the decorin protein core and EGFR, suggesting that decorin is biologically...
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Báo cáo khoa học: Proteoglycans in health and disease: the multiple roles of syndecan shedding ppt
... HEXXHXXGXXH) and a conserved methionine (Met-turn) supporting the catalytic zinc Interaction between cysteine–zinc maintains proMMPs in an inactive state by preventing a water molecule from binding to ... (GAIP)-interacting C-terminus ⁄ synectin and calcium ⁄ calmodulin-associated serine kinase, since the C2 region contains a class II PSD-95 ⁄ Discs-large ⁄ Zonula occludens protein-binding motif FXF, ... (Pro) containing a cysteine switch motif PRCGXPD (except for MMP23 which lacks the cysteine switch motif) that maintains them as inactive zymogens, and a catalytic domain with a zinc-binding site...
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Báo cáo khoa học: Proteoglycans in health and disease: new concepts for heparanase function in tumor progression and metastasis pptx
... Accumulating evidences indicate that HSPGs act to inhibit cellular invasion by promoting tight cell–cell and cell–ECM interactions, and by maintaining the structural integrity and self-assembly of ... protein-coding genes contain introns that are removed in the nucleus by RNA splicing and are often alternatively spliced Alternative splicing increases the coding capacity of the genome, generating ... enriched in lung carcinoma and chronic myeloid leukemia compared with control tissue and cells In this splice variant, 144 bp of intron are joined with exon 4, resulting in a 169-amino-acids protein...
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