l opg rank and traf6 mrnas by sf neutrophils from patients with ra and by healthy human blood cells
Báo cáo y học: "Pro-apoptotic Bid is required for the resolution of the effector phase of inflammatory arthritis" pdf
... H&E ankle sections were scored on a to scale for inflammation, with = normal, = minimal infiltration, = mild infiltration, = moderate infiltration, = marked infiltration, and = severe infiltration ... and B cells Figure ankles following transfer of K/BxN serum Bid-deficient mice develop a sustained and prolonged edema of the ankles following transfer of K/BxN serum Pooled serum (300 l) from ... temperature Samples were collected on a BD FACS Calibur at the St Louis University Flow Cytometry Core Facility, and the data were analyzed in FlowJo (TreeStar, Inc Ashland, OR) Total peripheral blood...
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Báo cáo khoa học: Neptunium uptake by serum transferrin potx
... impossible and cation transfer inside the cell is disabled Consequently, comparison between the lobe conformation in the holo and Np form is also essential Experimental procedures Np(IV) stock solution ... been tested by EXAFS and further spectroscopic and theoretical investigations are needed to support this model The average Np–ligand distances are in agreement with comparable crystallographic structures ... plutonium and interactions of plutonium with macroorganisms and plants In Avances in Plutonium Chemistry 1967–2000) Darleane Hoffman, American Nuclear Society, La Grange Park, Il, USA Sun H, Li...
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báo cáo hóa học: " Astrogliosis is delayed in type 1 interleukin-1 receptor-null mice following a penetrating brain injury" pptx
... mixed glial cultures, the level was very low in the cortical neuronal cultures and below the level of detection in the microglial cultures Altogether, these results suggest that brain cells are ... expected, IL-1β increased CP significantly in the astrocyte and mixed glial cultures Extracellular matrix molecules are independent of IL-1R1 (Fig and 6) Extracellular matrix (ECM) molecules play an ... Dijkstra CD: Demonstration of interleukin-1 beta in Lewis rat brain during experimental allergic encephalomyelitis by immunocytochemistry at the light and ultrastructural level J Neuroimmunol 1993,...
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báo cáo hóa học: " Treatment with gelsolin reduces brain inflammation and apoptotic signaling in mice following thermal injury" potx
... effects of human cord blood cells in a rat model of stroke Stem Cells Dev 2005, 14:595-604 20 Yin HL, Stossel TP: Control of cytoplasmic actin gel-sol transformation by gelsolin, a calcium-dependent ... model, an early, single dose of gelsolin can dramatically reduce mortality by ameliorating cerebral inflammatory lesions and apoptosis via acceleration of recruitment of monocytes and down-regulation ... collected and stored at -80°C until analysis for IL-2 by ELISA (ExCell Biology Inc., Shanghai, China) T cell proliferation was examined using a 3-(4, 5-dimethylthiazol -2-yl)- 2, 5-diphenyltetrazolium...
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Báo cáo khoa học: "Mucosal mast cell-derived chondroitin sulphate levels in and worm expulsion from FcRγ-knockout mice following oral challenge with Strongyloides venezuelensis" doc
... challenge Fig Number of adult worms (mean ± SD) recovered from the small intestines of immune and control FcRγ-KO and WT mice challenged orally with 300 lung-recovered L3 of S venezuelensis and ... mean daily EPG of animals sacrificed on day 13 post challenge are presented in Fig All control WT and KO animals as well as all challenged KO mice persistently shed eggs in their faeces until the ... mMCP-1 concentration Mast cells were enumerated in jejunal sections prepared on days and 13 post oral challenge Results (Table 1a) show that significantly higher numbers of mast cells were counted...
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Báo cáo y học: " PCEP enhances IgA mucosal immune responses in mice following different immunization routes with influenza virus antigens" pdf
... provided by grants from the Krembil Foundation and the Bill and Melinda Gates Foundation through the Grand Challenges in Global Health Initiative The assistance from Barry Carroll and Animal Care ... into the vaginal, nasal, and lung cavities, respectively, and subsequently withdrawn for collection All samples were promptly centrifuged and the resulting supernatants were collected and assayed ... PCEP with influenza X:31 antigen when administered by parenteral (subcutaneous), and mucosal (intranasal, oral, and intrarectal) routes We show that, while PCEP has adjuvant activity in all routes...
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Báo cáo y học: "Early Reversal of experimental colitis disease activity in mice following administration of an adenoviral IL-10 vector" pps
... single inflammatory cell infiltration of crypts, slight monocyte and neutrophil infiltrate; a score of signifies loss of multiple epithelial cells (in patches), obvious flattening of the epithelia, ... interleukin-8 production in human neutrophils Blood 1994, 83:2678-2683 Willems F, Marchant A, Delville JP, Gerard C, Delvaux A, Velu T: Interleukin-10 inhibits B7 and intercellular adhesion molecule-1 ... avoided Viral stocks and infected cells were handled only in a Class II laminar flow hood and maintained in a CO2 incubator designated for that purpose The concentration of total viral particle numbers...
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Báo cáo y học: " Pneumocystis murina colonization in immunocompetent surfactant protein A deficient mice following environmental exposure" pdf
... in an ELISA reader Isolation and Analysis of Pulmonary CD4+ and CD8+ T cells Cells were isolated and quantitated from the lungs as previously described [34] Briefly, lungs were removed and ground ... mice develop higher levels P murina infection than WT mice [24,25] Immunocompetent and CD4+ T-cell depleted KO mice also display delayed clearance following infection by intratracheal inoculation ... (KO) and WildType (WT) mice Mononuclear cells were isolated from the lungs of KO and WT mice with no experimental exposure to P murina CD4+ and CD8+ T cell populations were identified by cell surface...
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Báo cáo y học: "Matrix metalloproteinase-8 deficiency increases joint inflammation and bone erosion in the K/BxN serum-transfer arthritis model" pptx
... of inflammation by IL-1b and other molecules like PTX3, induction of maturation and activation of osteoclasts by IL-1b and PROKR2, and enhanced inflammatory infiltrate by IL-1b and possibly PROKR2 ... synovial lining and moderate infiltration of the sublining; = thickening of synovial lining and marked infiltration; and = thickening of synovial lining and severe infiltration Cartilage damage ... of cartilage with minor loss of surface cartilage; = moderate cartilage abnormalities including loss of superficial cartilage and moderate multifocal chondrocyte loss; and = marked cartilage destruction...
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Báo cáo khoa học: Brain lipid composition in postnatal iron-induced motor behavior alterations following chronic neuroleptic administration in mice potx
... nonalkaline metal in the human body and brain [12], is involved in several metabolic processes and is essential for a normal neurological development [13], and iron deficiency during critical periods ... placed in a sound-proofed wooden box with 12 cm thick walls and front panels and a small double-glass window to allow observation; each box had a dimmed lighting Mice were killed by cervical ... Ethical Experiments on Laboratory Animals (license S93 ⁄ 92 and S77 ⁄ 94, Stockholm, Sweden) Chemicals and reagents Lipid standards of l- a-phosphatidylcholine (PC from egg yolk) and N-acyl-d-sphingosine-1-phosphocholine...
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Báo cáo sinh học: "SERCA2a gene transfer improves electrocardiographic performance in aged mdx mice" pdf
... Mendell JR, Campbell K, Rodino-Klapac L, Sahenk Z, Shilling C, Lewis S, Bowles D, Gray S, Li C, Galloway G, Malik V, Coley B, Clark KR, Li J, Xiao X, Samulski J, McPhee SW, Samulski RJ, Walker ... is elevated at all ages J Neurol Sci 1991, 103:226-231 Alloatti G, Gallo MP, Penna C, Levi RC: Properties of cardiac cells from dystrophic mouse J Mol Cell Cardiol 1995, 27:1775-1779 Williams ... function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins J Mol Cell Cardiol 2007, 42:852-861 17 Kawase Y, Ly HQ, Prunier F, Lebeche D, Shi Y, Jin H, Hadri L, Yoneyama...
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báo cáo hóa học: " Boosting with intranasal dendrimeric Aβ1–15 but not Aβ1–15 peptide leads to an effective immune response following a single injection of Aβ1–40/42 in APP-tg mice" ppt
... nasal cavity Control mice received LT(R192G) alone All vaccinations were administered weekly for months Plasma and tissue collection Blood was collected from the tail bi-weekly and the plasma ... Pathologically there is localized deposition of cerebral β-amyloid (Aβ) protein, neuritic plaques, glial activation, neurofibrillary tangle formation, and neuronal loss [1] The cause of AD is still ... antibody for IL-4 and IFN-γ (BD PharMingen) Aβ ELISA Both soluble and insoluble brain Aβ levels were determined For soluble Aβ levels, frozen hemibrains were homogenized in volumes of TBS with a protease...
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báo cáo hóa học: " Interleukin-1 receptor 1 knockout has no effect on amyloid deposition in Tg2576 mice and does not alter efficacy following Aβ immunotherapy" pot
... amyloid deposition in these mice [36,37] Another member of the IL-1 superfamily, IL-1 receptor antagonist (IL 1Ra) [38], is also synthesized and released in parallel to IL-1β, IL-1α, and IL-18 IL- 1Ra ... C57BL/6.SJL) Groups of mice at various ages (6 months, months and 15 months of age) were killed and the levels of both SDSsoluble (SDS) and SDS-insoluble FA-extractable fractions of Aβ40 and ... Green KN, LaFerla FM: A dynamic relationship between intracellular and extracellular pools of Abeta Am J Pathol 2006, 168(1):184-194 Wilcock DM, DiCarlo G, Henderson D, Jackson J, Clarke K, Ugen...
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báo cáo hóa học:" SERCA2a gene transfer improves electrocardiographic performance in aged mdx mice" docx
... Mendell JR, Campbell K, Rodino-Klapac L, Sahenk Z, Shilling C, Lewis S, Bowles D, Gray S, Li C, Galloway G, Malik V, Coley B, Clark KR, Li J, Xiao X, Samulski J, McPhee SW, Samulski RJ, Walker ... is elevated at all ages J Neurol Sci 1991, 103:226-231 Alloatti G, Gallo MP, Penna C, Levi RC: Properties of cardiac cells from dystrophic mouse J Mol Cell Cardiol 1995, 27:1775-1779 Williams ... function in failing aortic-banded rat hearts by gene transfer of calcium cycling proteins J Mol Cell Cardiol 2007, 42:852-861 17 Kawase Y, Ly HQ, Prunier F, Lebeche D, Shi Y, Jin H, Hadri L, Yoneyama...
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báo cáo hóa học:" Ovarian hyperstimulation syndrome and prophylactic human embryo cryopreservation: analysis of reproductive outcome following thawed embryo transfer" pdf
... interval between retrieval and thaw/transfer, number (and developmental stage) of embryos transferred (ET), and livebirth-delivery rate All data were tabulated as mean ± SD Patients were periodically ... present and morphologically normal at baseline for all patients at risk for OHSS All patients underwent ultrasound-guided transvaginal oocyte retrieval at our facility without incident; the average ... Villasante A, Pacheco A, Pau E, Ruiz A, Pellicer A, Garcia-Velasco JA: Soluble vascular endothelial-cadherin levels correlate with clinical and biological aspects of severe ovarian hyperstimulation...
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Báo cáo khoa học: "Serum immunoglobulin fused interferon-Ձ inhibited tumor growth in athymic mice bearing colon 26 adenocarcinoma cells" ppsx
... harvested from blood samples obtained from the mice The following parameters were assayed: total protein (TPROT), albumin (ALB), total bilirubin (TBILI), aspartate aminotransferase (AST), alanine ... at low levels in many tissues and cell types and reaches high concentrations in the brain and pituitary FGF2 has been implicated in a multitude of physiologic and pathologic processes, including ... ± C , with a relative humidity of 50 ± 20% and a 12 h light/dark cycle After days of tumor cell inoculation, the mice were grouped as follows: control, 10 × and 50 × IFN concentrations All the...
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Báo cáo y học: "A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer." pps
... with IL-1β Approximately × 105 HSFs were plated in several wells of a 24-well plate Twenty-four hours later, a range of doses of rIL- 1Ra (from 0.13 to µg) or HIG-82-IL- 1Ra+ cells (ranging from ... cultured at a density of × 105 cells per well in 24-well plates with ml DMEM supplemented with 10% FBS and 1% penicillin-streptomycin Engineered cell lines To generate a cell line that provided a source ... IL-1 stimulation, and IL- 1Ra concentration immediately before and 48 hours after IL-1stimulation PGE2/IL- 1Ra levels for cultures receiving the IL- 1Ra producing cells are represented by triangles;...
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Characterization of Fabry mice treated with recombinant adeno-associated virus 2/8-mediated gene transfer pdf
... kidneys of wild-type mice were strongly labeled with α-Gal A, and most staining was observed in tubular epithelial cells (Fig 3A) Glomerular cells including podocytes and mesangial cells did not ... proteinuria and glomerulosclerosis can develop In addition, in the inner capillaries, the pores of endothelial cells underwent fenestration and formed an inclusion The mesangial cells became complex and ... previous study indicated that although the glycosphingolipids may accumulate in endothelial, glomerular, and tubular cells in Fabry disease, glomeruli and endothelial cells did not express the enzyme...
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Báo cáo y học: "Acetyl salicylic acid augments functional recovery following sciatic nerve crush in mice" pot
... nerve regeneration [5] Non-steroidal anti-inflammatory agent acetyl salicylic acid (ASA), in addition to its well known inhibitory action on cyclooxygenases, affects several cellular signalling pathways ... withdrawal reflex of the hind limb and vocalization in response to noxious stimulation like mechanical stimulation (pinch test) and pricking the plantar aspect of the lateral part of the foot with ... peripheral regeneration FEBS Journal 2005, 272:2628-38 Shiff SJ, Qiao L, Tsai L- L, Rigas B: Sulindac Sulfide, an Aspirin-like Compound, Inhibits Proliferation, Causes Cell Cycle Quiescence, and...
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Báo cáo y học: " Effect of oat bran on time to exhaustion, glycogen content and serum cytokine profile following exhaustive exercise" pdf
... Catholic University of Brasilia, Brasília/DF/Brazil 3Molecular Biology of the Cell Group, Institute of Biomedical Sciences, Department of Cell and Developmental Biology, University of São Paulo, ... minutes), the IL-6 has a close relationship with the amount of muscle glycogen and regulation of the homeostasis of blood glucose during long duration exercises Muscular glycogen and blood glucose are ... glycogen in small tissue samples Journal of Applied Physiology 1970, 28(2):234-236 Sambrook J, Russell DW: Molecular cloning: A laboratory manual Cold Spring Harbor Laboratory Press, Cold Spring Harbor,...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25