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is neuroimaging appropriate in patients with febrile seizures

báo cáo hóa học:

báo cáo hóa học: " Increased levels of HMGB1 and pro-inflammatory cytokines in children with febrile seizures" pot

Toán học

... susceptibility to seizures The causative role of cytokines in epileptogenesis remains to be elucidated Cytokines may contribute initially to incite seizures in the developing brain after being induced ... elevated in patients with infection and/or systemic inflammatory response syndrome, than in healthy control individuals [19,21] HMGB1 is involved in various diseases without obvious infections; ... in patients without a family history of febrile seizures than in patients with family history These findings may reflect compensatory activation of anti-inflammatory or anti-convulsive mechanisms,...
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Báo cáo khoa hoc:

Báo cáo khoa hoc:" Aortic distensibility measured by pulse-wave velocity is not modified in patients with Chagas'''' disease" pot

Báo cáo khoa học

... impaired in group that comprised patients with systolic dysfunction Also, the peak VO2 was significantly decreased in group patients with systolic dysfunction, in comparison with that in patients without ... that aortic distensibility is not impaired in patients with different forms of Chagas' disease, even in those with heart failure Our results observed in patients without CHF coincide with those ... arterial distensibility Data obtained in experimental studies support this issue by demonstrating that acute infection by trypanosoma cruzi causes inflammatory lesions in large arteries, affecting...
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báo cáo hóa học:

báo cáo hóa học: " Is global quality of life reduced before fracture in patients with low-energy wrist or hip fracture? A comparison with matched controls" docx

Hóa học - Dầu khí

... The wrist patients have a modest decrease in health-focused quality of life within physical domain and scores in accordance with controls within http://www.hqlo.com/content/6/1/90 mental domain ... of giving informed consent, and patients not capable of speaking Norwegian Data was collected over two years During this period, 324 wrist fracture patients and 456 hip fracture patients with ... of the patients with a wrist fracture and 307 of those with a hip fracture were examined at the Osteoporosis Centre Sixtyeight wrist and 210 hip fracture patients were excluded (21 wrist patients...
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báo cáo hóa học:

báo cáo hóa học:" The prosurvival activity of ascites against TRAIL is associated with a shorter disease-free interval in patients with ovarian cancer" docx

Hóa học - Dầu khí

... glycoprotein of high molecular weight which is used in the clinic as a marker of tumor burden There is indeed a strong correlation between rising and falling levels of serum CA125 with progression ... cells were pre-incubated for h with various fluids (10% v/v) obtained from women with advanced ovarian cancer and treated with increasing concentrations of TRAIL for 48 h or with cisplatin or paclitaxel ... OVC346 Consistent with our previous findings in CaOV3 cell line [10], we found that both OVC346 and OVC509 ascites induced Akt activation in primary tumor samples as determined by increased Akt...
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Báo cáo y học:

Báo cáo y học: "The spliceosomal autoantigen heterogeneous nuclear ribonucleoprotein A2 (hnRNP-A2) is a major T cell autoantigen in patients with systemic lupus erythematosus" potx

Báo cáo khoa học

... minute (cpm) obtained in cultures with antigen to mean cpm obtained in cultures incubated in the absence of antigen An SI ≥3.0 and a ∆cpm >1,000 (mean cpm obtained in cultures with antigen minus ... it is indistinguishable from the A2 protein of the heterogeneous nuclear ribonucleoprotein complex J Clin Invest 1992, 90:1061-1066 Hassfeld W, Steiner G, Studnicka-Benke A, Skriner K, Graninger ... for this antigen The data obtained suggest that hnRNP-A2 may constitute an important T cell autoantigen in patients with SLE, indicating a potential role for it in the pathogenesis of this disorder...
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Báo cáo y học:

Báo cáo y học: " Synovial fluid leukocyte apoptosis is inhibited in patients with very early rheumatoid arthriti" pdf

Báo cáo khoa học

... fluid neutrophil apoptosis was significantly lower in patients with RA than in patients with non-RA persistent synovitis (P = 0.0004) or in patients with resolving synovitis (P = 0.002) Results ... apoptosis in patients with very early inflammatory arthritis (a) Synovial fluid neutrophil apoptosis at clinical arthritis presentation in patients with very early inflammatory arthritis divided ... al.: Blockade of interleukin trans signaling suppresses T-cell resistance against apoptosis in chronic intestinal inflammation: evidence in crohn disease and experimental colitis in vivo Nat Med...
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Báo cáo y học:

Báo cáo y học: "Deficiency of functional mannose-binding lectin is not associated with infections in patients with systemic lupus erythematosu" pptx

Báo cáo khoa học

... regression model This finding is in line with a previous study on major infections in SLE patients in the Hopkins Lupus Cohort [32] Renal insufficiency is a possible risk factor for infections However, ... admission was required Furthermore, the high incidence of Herpes zoster infection, occurring at least one time in 14% of the patients, is in line with other studies in patients with SLE [1,31] With ... one infectious episode since lupus diagnosis in 50% of patients with SLE, and this high infection rate is confirmed by other studies reporting infectious complications in up to 45% of SLE patients...
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Báo cáo khoa học:

Báo cáo khoa học: "Prognosticators and Risk Grouping in Patients with Lung Metastasis from Nasopharyngeal Carcinoma: A more accurate and appropriate assessment of prognosis" doc

Báo cáo khoa học

... verified using the best available methods, including verifying the clinical attendance records and with direct telecommunication with the patient or their family Statistical Analysis Disease-free interval ... (n = 70) patients, respectively The histological types of 98.5% of the patients were non-keratinising or undifferentiated carcinoma (WHO type II or III) The distribution of patients within the ... hazards regression models risk subset included the patients with 0-2 independent prognostic factors (score 0-2), the intermediate-risk subset included the patients with 3-4 independent prognostic...
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Báo cáo y học:

Báo cáo y học: "The human anti-IL-1β monoclonal antibody ACZ885 is effective in joint inflammation models in mice and in a proof-of-concept study in patients with rheumatoid arthritis" doc

Báo cáo khoa học

... overexpressed in inflamed synovial tissue, in particular in the lining layer and in sublining cells [9], and it is elevated in draining lymph from affected joints [10] Furthermore, IL-1β is localized ... IL-1α In murine collagen-induced arthritis [6] and antigen-induced arthritis [7,8], inflammation and cartilage degradation were inhibited by blocking IL-1β but not IL-1α In RA patients, IL-1β is ... processing for paraffin embedding Tissue sections (7 μm) were stained with haematoxylin/eosin or safranin O/fast green Histopathological changes in the knee joints were scored in the patella/ femur...
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Báo cáo y học:

Báo cáo y học: "Rheumatoid cachexia is associated with dyslipidemia and low levels of atheroprotective natural antibodies against phosphorylcholine but not with dietary fat in patients with rheumatoid arthritis: a cross-sectional study" pdf

Báo cáo khoa học

... of RA disease is change in body composition, with reduced fat free mass (FFM), of which muscle mass is the largest component [13,14] The decline in FFM is, in RA, often associated with increased ... gastric ulcer or intestinal surgery, known eating disorder or steroid injections within weeks The patient characteristics are shown in Table Consequently, the patients had a fairly low disease activity ... DR, Morris CJ: Presence of foam cells containing oxidised low density lipoprotein in the synovial membrane from patients with rheumatoid arthritis Ann Rheum Dis 1993, 52:677-680 56 Nordin Fredrikson...
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Báo cáo y học:

Báo cáo y học: "Uric acid is a strong independent predictor of renal dysfunction in patients with rheumatoid arthritis" docx

Báo cáo khoa học

... file) Insulin resistance was evaluated from fasting glucose and insulin using the Homeostasis Model Assessment of Insulin Resistance (HOMA IR) [30] and the Quantitative Insulin Sensitivity Check Index ... insulin resistance and chronic kidney disease in nondiabetic patients, independent of other risk factors [64] Insulin resistance has also been described in patients with RA and may associate with ... dysfunction in patients with RA In this study, we focus on the potential association of UA with renal dysfunction in patients with RA and investigate whether such an association is independent...
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Báo cáo y học:

Báo cáo y học: " Sitagliptin is effective and safe as add-on to insulin in patients with absolute insulin deficiency: a case series" potx

Báo cáo khoa học

... preservation [1-3] Recently, sitagliptin, the first DPP-4 inhibitor launched on the market, has been approved for use in combination with insulin Sitagliptin combined with insulin significantly reduces blood ... dosage of insulin units may be a solution to this problem; however, in practice, this can cause an increased risk of hypoglycemia and weight gain Incretin-based drugs (GLP-1 receptor agonists and ... b-cells However, whether this is the case in humans has not been investigated The possibility of using GLP-1 analogues in patients with type diabetes is now emerging [6] As in the animal model [5],...
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Báo cáo y học:

Báo cáo y học: " KL-6 concentration in pulmonary epithelial lining fluid is a useful prognostic indicator in patients with acute respiratory distress syndrome" ppt

Báo cáo khoa học

... diagnosis of ARDS The most important finding in the present study was that the marked elevation of ELF KL-6 within days after the diagnosis appeared to correlate with poor prognosis in ARDS patients ... serum between the patients with primary and secondary ARDS or between the patients with and without preexisting ILD Interestingly, we found no significant difference in each comparison These data ... DW, Martin TR, Wiener-Kronish JP: Pathogenesis of septic shock in Pseudomonas aeruginosa pneumonia J Clin Invest 1999, 104:743-750 10 Bitterman PB: Pathogenesis of fibrosis in acute lung injury...
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Báo cáo y học:

Báo cáo y học: " Decreased respiratory system compliance on the sixth day of mechanical ventilation is a predictor of death in patients with established acute lung injury" ppt

Báo cáo khoa học

... mortality in ALI patients ventilated with lung-protective ventilation during this stage of disease In addition, if prospectively validated, these findings may help identify patients who are failing ... Other studies, including the Kings County Lung Injury Project and the ARDSNet trial of steroids for persistent ARDS, reported surprisingly low mortality rates in patients requiring prolonged ventilation ... cumulative risk of complications associated with mechanical ventilation, including ventilator- associated pneumonia and sepsis, increases with each ventilator day, we were surprised to find that...
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Báo cáo y học:

Báo cáo y học: " GDF-15 is abundantly expressed in plexiform lesions in patients with pulmonary arterial hypertension and affects proliferation and apoptosis of pulmonary endothelial cells" ppsx

Báo cáo khoa học

... levels are increased in scleroderma patients with pulmonary hypertension and GDF-15 protein was predominantly located in monocytes infiltrating the lung tissue [18] In the present study we investigated ... physiology Intense signal for GDF 15 is noted in cells lining vascular channels Inset shows prominent luminal staining of GDF-15 in endothelial cells (arrowhead) Note lower signal for GDF-15 in the ... different cytokines and signaling pathways interact with each other, it is difficult to define the precise role of a single cytokine in such a complex milieu Key players in vascular remodeling of PAH...
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Báo cáo y học:

Báo cáo y học: "Airflow limitation or static hyperinflation: which is more closely related to dyspnea with activities of daily living in patients with COPD?" ppt

Báo cáo khoa học

... because dynamic hyperinflation is the main cause of shortness of breath in patients with COPD However, breathlessness during exercise is measured in most studies to evaluate this relationship Purpose ... clinical dyspnea is also unknown There are also important considerations in the clinical practice setting A common misunderstanding is that hypoxemia is causing dyspnea, and proper oxygen administration ... EELV is maintained at a level above the statically determined relaxation volume of the respiratory system In flow-limited patients, the mechanical time-constant for lung emptying is increased in...
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Báo cáo y học:

Báo cáo y học: " Individual-level socioeconomic status is associated with worse asthma morbidity in patients with asthma" pps

Báo cáo khoa học

... and increased risk of emergency department visits and hospitalizations for asthma [29,30] These findings are also in line with previous studies linking lower SES (assessed using arealevel and individual-level ... even with the inclusion of all covariates These findings are consistent with previous studies finding significant associations between lower childhood SES and worse asthma morbidity, including increased ... whom 1739 patients (91%) were screened for inclusion in the study (the remaining 165 patients had insufficient medical information with which to conduct pre-screening) A total of 885 patients...
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Báo cáo y học:

Báo cáo y học: "Seropositivity is associated with insulin resistance in patients with early inflammatory polyarthritis: results from the Norfolk" pot

Báo cáo khoa học

... especially in seropositive disease In established RA, insulin resistance (IR) is increased and associated with CVD We investigated factors associated with IR in an inception cohort of patients with ... arthritis, Insulin Resistance factor, Early inflammatory Introduction Cardiovascular disease (CVD) remains the leading cause of death in patients with inflammatory polyarthritis (IP) and is particularly ... associated with seropositive disease [1-4] Insulin resistance (IR) is known to be increased in patients with established RA [5,6] and has been shown to be a risk factor for both clinical CVD...
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Báo cáo y học:

Báo cáo y học: "Protein-losing enteropathy in patients with Fontan circulation: is it triggered by infection" ppt

Báo cáo khoa học

... system during the early development of PLE, rather than a causal factor However, reports of opportunistic infections in patients with PLE are rare [5,10] This finding is in agreement with our ... albumin, × 50 ml 20%/day), a single immunglobulin infusion (Sandoglobin®), C1-esterase-inhibitor (Berinert®) and prednisolon (3 × mg/day per orally; during the early phase, in addition, 10–20 mg intravenously) ... 7, and was increased at this time Protein levels were below the normal range at PLE onset; α1-globulin, α2-globulin and β-globulin were elevated in most patients, whereas γ-globulin was below...
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