insulin resistance in alzheimer apos s disease a novel therapeutic target
Infliximab therapy in pediatric Crohn’s disease: a review docx
... Dovepress Parashette et al to frequent relapses and less than favorable maintenance of clinical remission Since CD may progress from intestinal inflammation to strictures and penetrating disease, including ... Franchis and coworkers showed that once patients achieved disease remission on mesalamine, less than 50% of patients were able to sustain disease remission after one year of maintenance therapy.9 ... Investigation and treatment of gastointestinal disease; Pharmacology of drugs used in the alimentary tract; Immunology/genetics/genomics related to gastrointestinal disease This journal is indexed...
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Tài liệu Báo cáo khoa học: Emerging pathways in genetic Parkinson’s disease: Autosomal-recessive genes in Parkinson’s disease – a common pathway? docx
... Mitochondria in the aetiology and pathogenesis of Parkinson s disease Lancet Neurol 7, 97–109 Hayashi S, Wakabayashi K, Ishikawa A, Nagai H, Saito M, Maruyama M, Takahashi T, Ozawa T, Tsuji S & Takahashi ... Proposed cross-talk of pathways Extracellular and intracellular cues activate universal cellsignalling cascades including MAPK and phosphatidylinositol 3-kinase (PI3K) pathways that can target ... Autosomal recessive genes in Parkinson s disease contains a putative catalytic serine–threonine kinase domain and shares homology with calmodulin-dependant protein kinase In addition, preliminary evidence...
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báo cáo hóa học: "Effect of step-synchronized vibration stimulation of soles on gait in Parkinson''''s disease: a pilot study" doc
... measured the gait distance with a "MeterMan" distance-measuring wheel (Winnebago, MN) Statistical analysis was performed using statistical software JPM 5.1 (SAS Institute, Cary, NC) The effects ... feedback and to assess its role in generation of parkinsonian gait The foot pressure activates the plantar mechanoreceptors that mediate postural adjustment during the stance phases of the step ... on state LEDD = the levodopa equivalent daily dose Background Parkinson 's disease (PD) is caused by a dopamine deficiency in the basal ganglia that results in characteristic motor abnormalities...
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báo cáo hóa học: " Effect of optical flow versus attentional strategy on gait in Parkinson''''s Disease: a study with a portable optical stimulating device" pptx
... kinematics/kinetics patterns Conclusion Other areas (Attentional cue) Progression of Parkinson s Disease Figure stimuli Schematization of responsiveness of PD subjects to visual Schematization of responsiveness ... motor area and other areas (associative, sensory), versus disease progression The results of the present study suggest that gait behaviours of PD subjects can be influenced by optical stimulation ... the statistical analysis AM participated in the design of the study and data analysis GA participated in the design of the study and in drafting the manuscript, performed subjects selection and...
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báo cáo hóa học: " Replication of the association of HLA-B7 with Alzheimer''''s disease: a role for homozygosity?" pptx
... leukocyte antigen; NINCDS-ADRDA, National Institute of Neurological, Communicative Diseases and Stroke -Alzheimer' s Disease and Related Diseases Association; NK, natural killer; OPTIMA, Oxford ... 357:436-439 Small GW, Scott WK, Komo S, Yamaoka LH, Farrer LA, Auerbach SH, Saunders AM, Roses AD, Haines JL, Pericak-Vance MA: No association between the HLA -A2 allele and Alzheimer disease Neurogenetics ... D, Stadlan EM: Clinical diagnosis of Alzheimer' s disease: report of the NINCDS-ADRDA work group under the auspices of Department of Health and Human Services task force on Alzheimer' s disease...
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Báo cáo hóa học: " Bilateral pyosalpinx in a peripubescent female with Hirschsprung’s disease: a case report" docx
... hydronephrosis and hypoplasia [2] The association of hydrosalpinx and Hirschsprung s disease was previously suggested in 2007 by Merlini et al In this case series the author suggest that bilateral hydrosalpinges ... found in a pubmed search from 1980-present which discusses hydrosalpinx or pyosalpinx in association with Hirschsprung disease [3] Pyosalpinx is the acute inflammation of the salpinx which is most ... shown around the fallopian tube anatomical location of these two diseases processes suggest that they may be associated Hirschsprung disease is an uncommon congenital disorder that affects in 5000...
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báo cáo khoa học: " Connectedness of healthcare professionals involved in the treatment of patients with Parkinson’s disease: a social networks study" pot
... consensus among the clinical authors of this paper We hypothesized that health professionals treating many Parkinson patients and health professionals in specialized hospital settings would have ... centralization, thus that positional advantages are unequally distributed domains A second limitation was that the measure of professional contacts was crude and not validated against a gold standard However, ... less was considered significant We used Excel to store and manage data files and UCINET for descriptions and statistical analysis Finally, we performed an explorative factor analysis (principal...
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báo cáo khoa học: "Effect of growth hormone replacement therapy in a boy with Dent’s disease: a case report" ppt
... caries, high palate and slight genus valgus, he had no other abnormalities His blood pressure was normal and his bone age was years A laboratory test was positive for proteinuria He had an elevated ... patients were not always affected by rickets Also, some patients with Dent s disease have been observed to have extrarenal manifestations such as mild intellectual impairment, hypotonia and cataracts, ... Lowe syndrome is referred as Dent s disease type [11] The most striking physical sign in the first described patient with Dent s disease and hypophosphatemic rickets was the shortness of stature...
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báo cáo khoa học: " Primary adenocarcinoma of the stomach in von Recklinghausen’s disease with high serum levels of multiple tumor markers: a case report" ppsx
... findings of pathologic examinations in gastric carcinoma These have shown significantly higher marker levels associated with gastric serosa invasion by the neoplasia and invasion of veins or lymphatic ... AFP-producing gastric adenocarcinomas with a high serum AFP level and synchronous hepatic metastasis Gastric cancers that secrete AFP are rare The first case was described in 1970 [11] AFP-secreting gastric ... vessels into the gastric wall as well as lymph-nodal metastases [14] A more advanced stage of gastric cancer (stage III and IV) results in higher serum levels of CA 72-4 Our patient had a normal...
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báo cáo khoa học: "Partial tetraplegic syndrome as a complication of a mobilizing/manipulating procedure of the cervical spine in a man with Forestier’s disease: a case report" pot
... serious complications associated with spinal manipulation They are specifically reported in cases with pre-existing underlying spinal pathologies, such as osteoporosis, tumors or metastases [6,17,18] ... Conclusions The case serves as a reminder to health care providers of the potentially severe complications associated with cervical spine mobilization/manipulation It emphasizes that cases such as ... shows radiographic imaging results obtained at the six-month followup demonstrating no changes in alignment, intact hardware and osseous consolidation Subsequent to the last follow-up, our patient...
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báo cáo khoa học: "Budd-Chiari syndrome in a 25-year-old woman with Behçet’s disease: a case report and review of the literature" pps
... genital ulceration, skin lesions and a positive skin pathergy test Evidence in countries where Behçet s disease is prevalent suggests that this disease should be included among the diagnostic possibilities ... course of Behcet s disease: clinical and laboratory analysis of four cases Joint Bone Spine 2007, 74(3):245-248 12 Saatci I, Ozmen M, Balkanci F, Akhan O, Senaati S: Behcet s disease in the etiology ... 150(8):587-590 Jayachandran NV, Rajasekhar L, Chandrasekhara PK, Kanchinadham S, Narsimulu G: Multiple peripheral arterial and aortic aneurysms in Behcet s syndrome: a case report Clin Rheumatol 2008,...
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báo cáo khoa học: " Duodenal gastrointestinal stromal tumor resembling a pancreatic neuroendocrine tumor in a patient with neurofibromatosis type I (von Recklinghausen’s disease): a case report" potx
... Recklinghausen s disease) NF1-associated gastrointestinal lesions include not only GIST, but also hyperplastic lesions of intestinal neural tissue and its supporting structures and endocrine cell tumors of ... surgical methods NF1-associated gastrointestinal lesions include not only GISTs, but also hyperplastic lesions of intestinal neural tissue and its supporting structures, and endocrine cell tumors ... growth and signs of malignancy Small tumors are depicted on CT scans as sharply marginated smooth masses with moderate contrast enhancement [7] In our case report, the patient s radiological findings...
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Báo cáo y học: "Leptospirosis presenting in a woman with fulminant hepatic failure from Wilson’s disease: a case report" ppsx
... Wilson s disease According to guidelines from the American Association for the Study of Liver Diseases (AASLD) patients in whom Wilson s disease is suspected should undergo screening with serum ... Wilson s disease include age < 35 years, Coombs negative hemolytic anemia and low serum alkaline phosphatase level, all of which applied to our patient Diagnosis was established on the basis of Kayser-Fleischer ... of acute hepatitis and encephalopathy in a person with no history of liver disease [5] Conclusions The clinician should suspect an underlying disease in an unexplained liver failure associated...
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Báo cáo y học: "Leptospirosis presenting in a woman with fulminant hepatic failure from Wilson’s disease: a case report" pdf
... Wilson s disease According to guidelines from the American Association for the Study of Liver Diseases (AASLD) patients in whom Wilson s disease is suspected should undergo screening with serum ... Wilson s disease include age < 35 years, Coombs negative hemolytic anemia and low serum alkaline phosphatase level, all of which applied to our patient Diagnosis was established on the basis of Kayser-Fleischer ... of acute hepatitis and encephalopathy in a person with no history of liver disease [5] Conclusions The clinician should suspect an underlying disease in an unexplained liver failure associated...
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Báo cáo y học: "Association of the T allele of an intronic single nucleotide polymorphism in the colony stimulating factor 1 receptor with Crohn''''s disease: a case-control study" ppt
... Suzuki A, Kochi Y, Sawada T, Suzuki M, Nagasaki M, Ohtsuki M, Ono M, Furukawa H, Nagashima M, Yoshino S, Mabuchi A, Sekine A, Saito S, Takahashi A, Tsunoda T, Nakamura Y, Yamamoto K: An intronic SNP ... Stat3 transcription factor (in monocytes) results in inflammatory bowel disease in rodents [22,23] These data suggest that a signaling pathway involving G alpha i2, Stat3 and CSF1R is critical ... cells, including Paneth cells [5] Crohn 's disease- associated mutations in NOD2 result in defective NF kappa B activation, suggesting that Crohn 's disease may represent, in part, a defect in innate...
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Báo cáo y học: "Recurrent acute myocardial infarction with coronary artery aneurysm in a patient with Behçet’s disease: a case report" ppsx
... revision References Ioakimidis D, Georganas C, Panagoulis C, Gournizakis A, Iliopoulos A, Kremastinos D, Kontomerkos T: A case of AdamantiadisBehcet s syndrome presenting as myocardial infarction ... leads Laboratory tests showed elevation of plasma total CK and CK-MB activities He was diagnosed with an acute anterior wall myocardial infarction Medical treatment was started but since he had ... declare that they have no competing interests Authors’ contributions Discussion Vascular involvement is a well-known characteristic of BD Large vessel disease or acute cerebrovascular infarction in...
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Báo cáo y học: "A 47-year-old man with neuro-Sweet syndrome in association with Crohn’s disease: a case report" ppsx
... kidneys may be involved Hisanaga et al have proposed diagnostic criteria for neuro-Sweet disease [5] We describe a case of neuro-Sweet disease in a patient with Crohn s disease, an association ... leukocytoclastic vasculitis are usually absent Aseptic neutrophilic inflammation may also be found in other sites such as bones, intestines, liver, aorta, lungs and muscles [2] A closely-related syndrome ... contained an infiltrate of neutrophils and nuclear dust was also present These findings supported the clinical diagnosis of acute neutrophilic dermatosis (Sweet s disease. ) On days 4-6 of admission,...
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Báo cáo y học: " Relapsing macrophage activating syndrome in a 15-year-old girl with Still''''s disease: a case report" pps
... cases of HLH [15] http://www.jmedicalcasereports.com/content/3/1/138 Abbreviations ALT: alanine transaminase; ARDS: acute respiratory distress syndrome; AST: aspartate aminotransferase; ATG: antihuman ... cytokines increase ferritin synthesis [5] Since ferritin levels are not that high in other rheumatologic diseases, it was suggested as a candidate for a serologic marker for the diagnosis and ... the patient 's clinical and laboratory studies, a diagnosis of Still 's disease was made Three days after admission to the hospital, her liver enzymes became elevated Two days later, the patient...
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Báo cáo y học: "Sweet''''s syndrome in a patient with Crohn''''s disease: a case report" pot
... collagen vascular diseases Rheumatoid arthritis, systemic lupus erythematosus, mixed connective tissue disease, hashimoto thyroiditis, Sjogren 's disease, behcet 's disease Medications Furosemide, ... gastrointestinal tract infection, vaccination or associated with inflammatory diseases such as autoimmune disorders, infections, hemoproliferative disorders, solid malignant tumors or pregnancy, ... due to solid tumors including breast, genitourinary and gastrointestinal malignancies [7] Other causes of Sweet 's syndrome are listed in table Only a few cases of Sweet 's syndrome associated with...
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Báo cáo y học: " Non-Hodgkin''''s lymphoma in a woman with adult-onset Still''''s disease: a case report" pptx
... Yamaguchi M, Ohta A, Tsunematsu T, Kasukawa R, Mizushima Y, Kashiwagi H, Kashiwazaki S, Tanimoto K, Matsumoto Y, Ota T, et al.: Preliminary criteria for classification of adult Still 's disease ... 20:1788-1792 Sono H, Matsuo K, Miyazato H, Sakaguchi M, Matsuda M, Hamada K, Tatsumi Y, Maeda Y, Funauchi M, Kanamaru A: A case of adultonset Still 's disease complicated by non-Hodgkin 's lymphoma Lupus ... Rheumatol 1995, 34:984-988 Kojima M, Nakamura S, Miyawaki S, Yashiro K, Oyama T, Itoh H, Sakata N, Sugihara S, Masawa N: Lymph node lesion in adultonset Still 's disease resembling peripheral T-cell...
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