inhibitors of hemopoietic stem cell proliferation
Báo cáo y học: " Successful treatment of severe sinusoidal obstruction syndrome despite multiple organ failure with defibrotide after allogeneic stem cell transplantation: a case report" ppsx
... GB, Guinan EC: Multi-institutional use of defibrotide in 88 patients after stem cell transplantation Page of (page number not for citation purposes) Journal of Medical Case Reports 2009, 3:6164 ... Rodriguez V, Khan SP: Use of prophylactic anticoagulation and the risk of hepatic venoocclusive disease in patients undergoing hematopoietic stem cell transplantation: a systematic review and meta-analysis ... general, management of SOS should be based on prophylaxis: identification of patients at risk, avoidance of SOSinducing therapies, preventative medical therapy [9] and, finally, therapy of the syndrome...
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Báo cáo khoa học: "Year in review 2006: Critical Care – multiple organ failure, sepsis, and shock" doc
... cultures of human umbilical vein endothelial cells (HUVECs) and neutrophils freshly isolated from blood of male healthy volunteers were used Expression of the adhesion molecules VCAM-1 (vascular cell ... impairment of already diminished heart function of aged rats Interestingly, the endotoxemia-induced decrease of myofilament Ca2+ responsiveness was not seen in senescent hearts This finding could be of ... (28°C), in which hour of aortic cross-clamping was anticipated by 30 minutes of cooling of animals and consequently was followed by 30 minutes of rewarming Additional cooling of hearts was performed...
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Báo cáo khoa học: "Bench-to-bedside review: Thrombocytopenia-associated multiple organ failure – a newly appreciated syndrome in the critically ill" pdf
... clinical indicator of TMA in patients with MOF, and resolution of thrombocytopenia is an indicator of resolving TMA Therefore, resolution of thrombocytopenia is the goal for directed use of therapy Activated ... first 24 hours of disease, and is required for an average of 15.8 days to restore platelet counts without recrudescence of thrombocytopenia The endpoint of therapy is resolution of thrombocytopenia ... least common manifestation of organ failure in patients with MOF However, despite reversal of shock, there are still patients who have DIC and coagulopathy is a predictor of mortality if it persists...
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Báo cáo y học: "Role of PPAR-δ in the development of zymosaninduced multiple organ failure: an experiment mice study" pot
... preparations were performed of the PEC for a differential estimation of the types of cells present Wright-Giemsa stained slides of all controls appeared to contain mostly mononuclear cells including resident ... members of the death receptor family of apoptosis-inducing cellular receptors [49] In this study, we have clearly shown the degree of cell death, assessed by immunohistochemical localization of FasL ... samples of Galuppo et al Journal of Inflammation 2010, 7:12 http://www.journal-inflammation.com/content/7/1/12 Page 25 of 28 Figure 20 Effect of GW0742 on liver injury Administration of zymosan...
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Báo cáo y học: " Successful treatment of HIV-associated multicentric Castleman’s disease and multiple organ failure with rituximab and supportive care: a case report" potx
... possible basis for this could have been the systemic manifestations of a “cytokine storm” associated with MCD; increased expression of IL-6 is typical of MCD Vasopressor and inotropic support with ... a continuous infusion of 20% dextrose for refractory hypoglycaemia To treat her acute renal failure and profound metabolic acidosis (serum lactate of 18.5 mmol/L), haemofiltration was undertaken ... 8.6 mmol/l C-reactive protein 140 mg/l Page of target early shock reversal and removal of IL-6, increased expression of which is a hallmark feature of MCD The chest radiograph progressed over...
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Báo cáo khoa học: "Early veno-venous haemodiafiltration for sepsis-related multiple organ failure" ppt
... confirm that early use of haemofiltration at a filtration rate of l/hour reduced the circulating concentration of cytokines associated with septic shock Increasing the rate of fluid exchange across ... threshold of 35 ml/kg per hour Use of 2,000 ml/hour haemofiltration in our group of patients, whose average body weight was 72 kg, would have resulted in an average convection exchange of 28 ml/kg ... group (nonresponders) there were 11 cases of bacterial pneumonia and seven cases of sepsis of extrapulmonary origin among medical patients, and two cases of peritonitis among surgical patients No...
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Báo cáo y học: " Decompressive laparotomy for abdominal compartment syndrome – a critical analysis" pps
... The cause of death of patients who underwent DL could be retrieved from only nine of the studies This accounted for only 29 out of the total of 123 patients who died The main cause of death after ... treatment of primary or secondary ACS (e.g., persistence of ACS after DL or development of a new ACS episode following definitive closure of the abdominal wall after the previous utilization of a ... half of the patients in the included studies eventually died, in spite of aggressive measures like DL First of all, patients who require DL are severely ill at the moment of decompression, Page of...
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Báo cáo y học: "Early venovenous haemodiafiltration for sepsis-related multiple organ failure" pptx
... out that we did not use highvolume haemofiltration It is true that we used a flow rate of only 2000 ml/hour, leading to an average convection exchange of 28 ml/kg per hour However, because we ... CVVHDF, we also used 1000 ml/hour of dialysis, leading to a ‘global exchange’ of about 40 ml/kg per hour Finally, Drs Jacobs and Brivet suggest that the lack of improvement in base excess in nonresponders ... Intensive Care Med 2001, 27:978-986 Page of (page number not for citation purposes) The EPISEPSIS Study Group: EPISEPSIS: a reappraisal of the epidemiology and outcome of severe sepsis in French intensive...
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Báo cáo khoa học: "Visualizing multiple organ failure: a method for analyzing temporal and dynamic relations between failing systems and interventions" pptx
... representation of the performance of LOD, SOFA and MODS: cardiovascular system Shown are data of another patient, illustrating differences between organ failure scores in assessing the cardiovascular system ... Competing interests YAK is the author and director of the Muavenet Intensive Care Information System, which is an open access, online academic information system The other authors declare that they have ... Assessment) score to describe organ dysfunction/failure On behalf of the Working Group on Sepsis-Related Problems of the European Society of Intensive Care Medicine Intensive Care Med 1996, 22:707-710...
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Báo cáo y học: " Multiple organ failure after trauma affects even long-term survival and functional status" pdf
... admission policy can explain most of this large variation in reported incidence of MOF In addition, the application of different scoring systems for assessment of MOF makes direct comparison difficult ... organ systems By default they were given a SOFA score of for the organ system not assessed The Injury Severity Score (ISS) [12], an anatomical description of injury, has not been part of the routine ... given by proxies The SOFA scoring system The SOFA score assesses the function of six different organ systems: respiratory (partial arterial oxygen pressure (PaO2)/ fraction of inspired oxygen (FiO2)),...
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Báo cáo y học: "Post-injury multiple organ failure and late outcome. Is it just an association" docx
... that the admission SOFA score, SOFA Max, and the changes in SOFA over the first 48 hours are correlated with mortality [9] Ulvik shows that measuring SOFA score on admission and SOFA max may categorise ... identification of patients who, developing MOF, are at major risk of poor longterm survival and impaired functional status Is this a suggestion for a standardisation of scoring MOF in trauma? ... M, Osborn J, SOFA Group: Application of SOFA score to trauma patients Intensive Care Med 1999, 25:389-394 Ferreira FL, Bota DP, Bross A, Mélot C, Vincent JL: Serial evaluation of SOFA score to...
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Báo cáo y học: " Year in review 2007: Critical Care – multiple organ failure and sepsi" pdf
... mediators of cellular injury Microparticles, small vesicles derived from a primary cell, have been identified in increased numbers in the blood of patients with a variety of diseases [10-12] A type of ... to report they often or always used central venous saturation as a monitor of therapeutic response (9.8% of respondents) or as an endpoint of resuscitation (19.4%) The majority of respondents ... transfusion [30], this feature of early goal-directed therapy remains one of the most controversial of the protocol This survey preceded a randomized trial of the use of hydroxyethyl starch in severe...
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Báo cáo y học: " Long-term survival of chronic dialysis patients following survival from an episode of multiple-organ failure" pdf
... disorders of the autonomic and peripheral nervous systems [7] There have been few data published describing the effect of an episode of multiple-organ failure on the long-term survival of patients ... record of all patients with ESRF Details extracted were age, sex, date of admission to both hospital and ICU, duration of mechanical ventilation, duration of multiple-organ support, Page of (page ... Patients For the purposes of this study critical illness was defined as admission to ICU and requirement for the support of two or more organ systems, and/or mechanical ventilation of more than 36 hours...
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Báo cáo y học: " Abdominal Compartment Syndrome: pathophysiology and definitions" ppt
... (compliance) of the abdominal wall Investigation into the physiologic effects of IAP on renal function in humans essentially began in 1947 with the work of Bradley [35] The experiences of surgeons ... aggravating the effects of elevated IAP and may reduce the threshold of IAH that causes the clinical manifestations of ACS The etiology for the patient's IAH is similarly of vital importance and ... contractility [49] Systemic vascular resistance (afterload) is increased through compression of both the aorta and systemic vasculature and pulmonary vascular resistance through compression of the pulmonary...
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Báo cáo y học: " Surgical management of abdominal compartment syndrome; indications and techniques" potx
... major source of morbidity is associated with the management and complications of the open abdomen Management of the open abdomen In view of the complicated and often fatal outcome of patients ... management and better understanding of the open abdomen, there is a high risk of persistent open abdomen requiring split-thickness skin grafting and delayed reconstruction of the abdominal wall (planned ... have a higher rate of fascial closure In addition, same principles of managing the open abdomen can be applied without additional equipment The major disadvantage is the loss of abdominal and back...
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Báo cáo y học: "Close relationship of tissue plasminogen activator–plasminogen activator inhibitor-1 complex with multiple organ dysfunction syndrome investigated by means of the artificial pancreas" doc
... score and parameters related to coagulation and fibrinolysis The mMOF score (mMOF score = MOF score – the points of coagulopathy of MOF score) was positively correlated with (a) the DIC score, (b) ... (1) Detection of soluble fibrin monomer (2) Increase of D-dimer (3) Increase of thrombin–antithrombin complex (4) Increase of plasmin-a2–plasmin inhibitor complex (5) Exacerbation of FDP, platelet, ... coagulopathy, MODS (MOF score) The relationships among coagulopathy, MODS (MOF/mMOF score), and endothelial cell injury (TM) were then investigated Finally, confirmation of the parameters related...
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Báo cáo khoa học: "Cutaneous vascular reactivity and flow motion response to vasopressin in advanced vasodilatory shock and severe postoperative multiple organ dysfunction syndrome" pot
... pre-ischaemic AUC of the Doppler signal nor reduced the magnitude of the reactive hyperaemic response at up to five minutes of forearm ischaemia Additionally, there was no difference in the response of the ... statistical evaluation Of all study patients, 55% (10 out of 18) were admitted to the intensive care unit after heart surgery The other eight patients were admitted because of severe systemic inflammatory ... to the results of a physiologic animal experiment, in whihc the effects of AVP on the microcirculation were analyzed in the skinfold of healthy hamsters [11] In that model, doses of AVP similar...
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Báo cáo y học: "Argatroban therapy for heparin-induced thrombocytopenia in ICU patients with multiple organ dysfunction syndrome: a retrospective study" pps
... argatroban bolus of 100 μg/kg followed by continuous infusion of argatroban In contrast, no bolus of argatroban was used in our study to avoid a peak response of anticoagulation with the risk of bleeding ... all sources of heparin and initiate an alternative anticoagulant on reasonable suspicion of HIT The choice of alternative anticoagulant agent and initial dose is at the discretion of the treating ... suspected HIT The primary objective of this observational analysis was to demonstrate dosingadjustment difficulties of argatroban, especially in the setting of MODS Materials and methods We retrospectively...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25