... not a risk factor for systemic scleroderma; only in the subgroup of males a trend for increasedrisk can be noted Conversely, occupational hand-arm vibration is associated withanincreased risk, ... incidence of anticentromer antibodies, and who are more likely to have diffuse disease compared with Caucasians and Australians [8] Although hormones are supposed to play a role in the aetiology of ... as sex, date of birth, date of diagnosis and the parents' country of origin The second part of the questionnaire was focussed on professional activities and exposure to harmful substances such...
... relative risks (RRs), and attributable risks (ARs) (AR risk ratio 1 /risk ratio) were estimated for AHR in the presence of obesity Correlates of BMI and AHR were studied with analysis of variance (ANOVA) ... between continuous BMI and airway responsiveness Two-way ANOVA was used to analyze means of grouped data, and least-square means post hoc analysis using the pooled variance was also performed ... 1.04–2.08) and an AR of 22%, whereas a higher risk was observed with obesity classes II and III, in which the ORs and ARs were 1.72 (95% CI 1.11–2.65) and 28% and 2.4 (95% CI 1.26–4.55) and 38%, respectively...
... and with the riskof fracture In patients with osteoporosis, there is a four fold to five fold increase in risk for fracture And for patients with osteoporosis and a history of fracture, the risk ... scientific advances are need to be made in an environment of legal and ethical safeguards that are acceptable to the general public [44] Fig Normal variation (mean and 8D) and change in BMD with age ... the mean BMD between age 20 and 40 yr, but this age range varies with DXA machine manufacture Source of Fig - Reference [29] In AIDS, the mainly suggested riskfactors for the development of osteopoenia...
... more than four units of red blood cell transfusion The mean number of units of red blood cells per transfused patient was 5.5 (range to 69) for these latter patients The characteristics of the ... the physician in charge of the patient The number of units of red blood cell transfused, whatever the evidence of upper gastrointestinal bleeding, was also recorded Red blood cell transfusions ... g/dl in an at -risk patient) [18] The study was approved by the Ethics Committee of the French Society of Critical Care Medicine (Société de Réanimation de Langue Française) Statistical analysis...
... 12-point standard curve was used The detection limit of the assay was 0.008 ng/ml of human recombinant MMP-1, 0.04 ng/ml of human recombinant MMP-3, 0.24 ng/ml of human recombinant MMP-9, and 0.031 ... expressions of MMP-3 and MMP-9 are elevated in the brain and are located around neurofibrillary tangles and amyloid plaques [6-8] The activity of MMPs might be associated with the metabolism of Ab, ... MMP-9, and 0.031 ng/ml of human recombinant TIMP-1 withan inter-assay variation of less than 10% The results are presented in ng/ml The ratios of MMP-1/TIMP-1, MMP-3/TIMP-1 and MMP9/TIMP-1 were...
... synthesis of angiogenic factors or an inhibition by angiostatic factors The aim of the present study was to analyze whether a decrease of the angiogenic factors VEGF and bFGF and an increase of the angiostatic ... levels of endostatin and the presence of anti-Scl-70 autoantibodies, anticentromere antibodies or antinuclear antibodies Similarly, there was no association of bFGF with any of the autoantibodies ... range,143–1151 pg/ml), patients without anticentromere antibodies (median, 453 pg/ml; range, 93–1143 pg/ml) and patients without detectable autoantibodies (P = 0.36) Autoantibodies and bFGF and...
... equal appearance of homo- and heterogeneous texture [4] After the administration of intravenous contrast, CT images reveal an equal percentage of mild enhancement and of absence of enhancement [4] ... writing and critical revision of the manuscript ESK contributed to research, acquisition of data, analysis, drafting and writing of the manuscript GID contributed to research, acquisition of the ... the data and writing of the manuscript PGD contributed to post-operative management, and acquisition and interpretation of the data AL contributed to post-operative management, writing and critical...
... subjects with and without insulin resistance: what is the role of chronic inflammation and how to weigh it non-invasively? J Inflamm (Lond) 2009, 16(6)-6 Duncan BB, Schmidt MI: The epidemiology of ... perhaps induce an irreversible change in insulin resistance and blood pressure regulation This may be one of the underlying mechanisms for the development of diabetes mellitus and hypertension ... into two groups: the group with normoglycemia was compared with the group with prediabetes Demographic, Anthropometric and Laboratory measures Standard demographic and anthropometric measures were...
... subjects with and without insulin resistance: what is the role of chronic inflammation and how to weigh it non-invasively? J Inflamm (Lond) 2009, 16(6)-6 Duncan BB, Schmidt MI: The epidemiology of ... perhaps induce an irreversible change in insulin resistance and blood pressure regulation This may be one of the underlying mechanisms for the development of diabetes mellitus and hypertension ... into two groups: the group with normoglycemia was compared with the group with prediabetes Demographic, Anthropometric and Laboratory measures Standard demographic and anthropometric measures were...
... Jones et al.: Parental and household smoking and the increasedriskof bronchitis, bronchiolitis and other lower respiratory infections in infancy: systematic review and meta-analysis Respiratory ... to be of lower quality primarily due to a combination of a lack of biochemical validation of passive smoke exposure, lack of representativeness of the study sample, and/or lack of adjusted analyses ... decreases risk Smoke increases risk Figure Relationship between passive smoke exposure by any household member and the riskof lower respiratory infection (LRI) in infancy using a meta-analysis of comparative...
... increasedriskof postoperative delirium Other independent riskfactors included increasing age, history of diabetes mellitus, longer duration of surgery, and occurrence of complications within ... presented as mean ± standard deviation or number of patients (percentage) Myocardial infarction of more than month before surgery Serum creatinine of greater than 177 μmol/L cSmoking of more than 20 cigarettes ... hypercortisolemia is a cause or an effect of postoperative delirium Studies found that an older population and patients with diabetes mellitus have anincreased baseline cortisol level and an attenuated negative...
... excluded from the analysis because of lack of EAA data and patients were excluded because of withdrawal of consent resulting in a sample size of 54 patients Of these 54 participants, the mean age was ... assay and data analysis, and contributed to the manuscript CDM was involved in study design and data analysis, and contributed to the manuscript All authors reviewed and approved the final manuscript ... significant riskof the development of postoperative infections Further research is necessary to assess whether a targeted strategy of rapid measurement of endotoxin levels coupled with a directed anti-endotoxin...
... between maternal use of loratadine in early pregnancy and birth of infants with hypospadias was the result of multiple testing Acknowledgments The study was supported by a grant from K A Wallenberg ... doubling of the risk, they would need a more than four times larger material The next strategy, which is the basis of the present study, is continued surveillance This necessitates the presence ofan ... significant As there is no prior hypothesis and at the surveillance process we study a large number of “exposures” (in this case drugs) and many outcomes (in this case different types of congenital...
... profiles of HO-1 and HO-2 in eight human cell lines by northern and western blot analyses (Fig 1A,B) Expression of HO-1 5334 A B C Fig Expression profiles of HO-1 and HO-2 in various human cell ... upper panels in (A) and (C) show the northern blot analysis of HO-1 and HO-2 mRNA in HeLa (A) and HepG2 cells (C) Each lane contains 15 lg total RNA The expression of 18S rRNA is also shown as an ... Asterisks represent significant differences compared with the control at h (*P < 0.05, **P < 0.01) (B and D) Western blot analysis of HO-1 and HO-2 proteins in HeLa (B) and HepG2 cells (D) Each lane...
... Overexpression and purification of the active-site domain of AcmA (A) SDS ⁄ 12.5% PAGE of cell extracts of 10 lL of E coli BL21(DE3) (pETAcmA) (lane 3) induced for h with IPTG Lane 2: 10 lL of purified ... masses (kDa) of standard proteins (lane M) are shown in the left margin Below the gel the lower part of lanes 5, and of the same gel is shown after week of renaturation The right half of the figure ... Expression of AcmA derivatives A1, A2, A3 and A4 in the L lactis NZ9000 mutants acmAD1 and acmAD1 DhtrA, visualized by zymographic analysis of culture supernatants of cells expressing the AcmA variants...
... Pennsylvania, without making any definite preparations to come to his assistance Notwithstanding this assurance, that a most important part of the plan of campaign had failed, through no fault of ... of the combatants knew what such strange sounds could mean It was Riedesel's Germans advancing to the attack, chanting battle hymns to the fierce refrain of the musketry and the loud shouts of ... junction with the army of Canada, by way of the Hudson This purpose he subsequently deferred for an advance into Pennsylvania, but Burgoyne asserts that he was not informed of the change of plan when...
... As with the agr feature, the value of the case feature cannot be instantiated 3To allow for long distance dependency, subject raising verbs must anchor an auxiliary tree, with identical root and ... Anchoring instantiates the agr feature of the anchor node as 3sg which has the effect (due to the reentrancy in the unanchored tree) of instantiating the agr feature at the subject node as 3sg Anchored ... On the other hand, the EDOL has the potential to eliminate some or all of feature percolation, and in the remainder of this section, we explain how An LTAG consists of a set of unanchored trees...
... species Loss -of- function mutations, such as nonsense mutations, are the molecular basis of many recessive alleles, which can greatly affect the genome ofan organism and are the cause of many genetic ... analysis software; WAF and PS analyzed and interpreted the data, and wrote the manuscript Both authors read and approved the final manuscript Schmid and Flegel Journal of Translational Medicine ... (orange), and ω = (red) The list is sorted according to the mean riskof the codons encoding a specific amino acid Schmid and Flegel Journal of Translational Medicine 2011, 9:87 http://www.translational-medicine.com/content/9/1/87...
... study concept and design, acquisition of data, analysis and interpretation of data, and drafting of the manuscript Hiroyasu Iso participated in analysis and interpretation of data, and the help ... evaluation of well-being among Japanese, and examined factors associated with "Ikigai", which is withan awareness of importance to use the term originated in the basis of cultural background and social ... 43.7% of female reported less than million yen as their annual income However, differences in satisfaction with living standards between male and female were not significant, with 63.5% of male and...
... Thus, the GHG effects ofanincreased use of wood within Switzerland are of particular interest The contributions of the different GHG-relevant mechanisms ofanincreased use of wood over time are ... the importance and dynamics of different GHGrelated effects ofanincreased use of wood within technosphere One important effect ofanincreased use of wood was neglected: the decline of the carbon ... with product emissions of around 18% of the total effect ofanincreased use of wood in Switzerland If one considers the effect ofanincreased use of wood in the mirror of the reduction commitment...