host gene polymorphisms and disease treatment outcomes in hiv and viral coinfections
Báo cáo y học: "Cytokine gene polymorphisms and atopic disease in two European cohorts. (ECRHS-Basel and SAPALDIA)" pot
... Holgate ST, Holloway JW: Polymorphisms in the interleukin-4 and interleukin-4 receptor alpha chain genes confer susceptibility to asthma and atopy in a Caucasian population Clin Exp Allergy 2003, ... differences in linkage disequilibrium between study population [30], chance findings and publication bias, as well as heterogeneity in genetic and environmental modifiers of specific gene/ disease ... SC: Polymorphisms of interleukin receptor gene and interleukin 10 gene are not associated with Graves' disease in the UK Autoimmunity 2004, 37:189-194 Woo JG, Assa'ad A, Heizer AB, Bernstein JA,...
- 9
- 291
- 0
Báo cáo y học: "Vitamin D receptor gene polymorphisms and susceptibility of hand osteoarthritis in Finnish wome" pdf
... reading of grade 2–4 in at least three joints of the fingers OA was defined to be symmetrical if at least two symmetrical pairs of joints (the same joint in both hands) were affected Our findings ... subset of hand OA in women [28,35-37], with three major determinants of the pattern of polyarticular involvement being symmetry, clustering by row, and clustering by ray (in descending order of ... contrast the findings in the studies of osteophytes formation in the knee [17-19] and the lumbar spine [48], but agree with the findings related to the severity and presence of lumbar spine osteophytes...
- 9
- 613
- 0
Báo cáo y học: "Cytokine polymorphisms influence treatment outcomes in SLE patients treated with antimalarial drugs" ppsx
... cytokines, this being particularly true in the case of IL-10 and TNFα, which are mutually regulated and have complex and predominantly opposing roles in systemic inflammatory responses In a previous ... capable of reducing pro-inflammatory cytokines in vivo Considering the central role that IL-10 and TNFα cytokines play in the pathogenesis of SLE, it is possible that different cytokine production ... blocked with 1% casein in Tris Buffered Saline (TBS) for two hours at 37°C Samples and TNFα standards (R&D) were diluted in blocking solution and incubated for 18 serum levels in systemic lupus...
- 9
- 347
- 0
Báo cáo khoa học: "Intra-arterial chemoradiation for T3-4 oral cavity cancer: Treatment outcomes in comparison to oropharyngeal and hypopharyngeal carcinoma" pot
... concept and design, acquisition of data, analysis and interpretation of data, drafting and revising the manuscript KTR: contributed to concept and design, analysis and interpretation of data and ... and revising the manuscript, SS: Helped in concept and design and revising the manuscript; FV helped in acquisition of data and revision of the manuscript All authors read and approved final manuscript ... oropharyngeal and hypopharyngeal carcinoma: Local failure, defined as histological evidence of carcinoma at the local site within months following the completion of treatment (persistent disease) ,...
- 6
- 380
- 0
Báo cáo y học: "Lack of association between mannose-binding lectin gene polymorphisms and juvenile idiopathic arthritis in a Han population from the Hubei province of China" docx
... Science and Technology in Wuhan City, Hubei province, China Participation was voluntary Detection of mannose-binding lectin gene polymorphisms Polymorphisms in codons 54 and 57 of the MBL gene were ... Turner MW: Mannose-binding lectin: the pluripotent molecule of the innate immune system Immunol Today 1996, 17:532-540 Turner MW: The role of mannose-binding lectin in health and disease Mol Immunol ... as follows: an initial denaturation at 94°C for minutes; 34 cycles of denaturation at 94°C for 30 seconds, annealing at 60°C for minute and extension at 72°C for minute; and a final elongation...
- 4
- 318
- 0
FACTORS ASSOCIATED WITH TREATMENT OUTCOMES IN PULMONARY TUBERCULOSIS IN NORTHEASTERN THAILAND pptx
... treatment outcomes (treatment failure/death, treatment interruption and cure /treatment completion) were evaluated in relation to the patient demographic data, baseline clinical characteristics and clinical ... were independently related to treatment interruption This is in agreement with previous studies suggesting that multiple factors are involved in the success of TB treatment, and that developing ... a short course of combined chemotherapy with isoniazid, rifampicin, pyrazinamide, and ethambutol as an induction regimen and was followed by isoniazid and rifampicin as maintenance drugs The median...
- 7
- 359
- 1
báo cáo hóa học:" Population preference values for treatment outcomes in chronic lymphocytic leukaemia: a cross-sectional utility study" pdf
... England or Scotland, aged 18 or over, and capable of giving informed consent The interviews were conducted inperson, and the participants completed a demographic questionnaire and, prior to beginning ... wheel using 2-color pie charts to illustrate the different probabilities Study participants were recruited from the general population in the UK, including both England and Scotland, in March ... between staying in the health state and taking the gamble Utility scores range from 0.0, reflecting being dead, to 1.0, reflecting full health A decision rule was implemented for eliminating illogical...
- 9
- 345
- 0
Báo cáo y học: "Thrombotic gene polymorphisms and postoperative outcome after coronary artery bypass graft surgery" ppt
... possible links between factor V Leiden gene G1691A (FVL), prothrombin/factor II G20210A (PT G20210A), and angiotensin-converting enzyme gene insertion/deletion polymorphism (ACE-ins/ del) and the ... polymorphisms, both of which increase circulating thrombin generation [9] Regarding surgical outcomes, however, Völzke et al found no association between FVL and glycoprotein IIIa PlA1/PlA2 gene ... occlusion and left ventricular aneurysm is more likely in FVL and PT G20210A carriers The findings of a recent study regarding the increased frequencies of FVL or prothrombin variant G20210A in patients...
- 8
- 311
- 0
báo cáo khoa học: "CYP1A1 MspI and exon7 gene polymorphisms and lung cancer risk: An updated meta-analysis and review" pdf
... risk in chinese population [in Chinese] Carcinogenesis Teratogenesis and Mutagenesis 1999, 11:228-230 34 Hu YL, Zhang Qi: Genetic Polymorphisms of CYP1A1 and Susceptibility of Lung Cancer [in Chinese] ... of the CYP1A1 and GSTM1 genes and their combined effects on individual susceptibility to lung cancer in a chinese pupulation [in Chinese] Chin J Med Genet 2001, 18:125-127 38 Ratnasinghe D, Tangrea ... Husgafvel-Pursiainen K, Karjalainen A, Anttila S, Vainio H: Pointmutational MspI and Ile-Val polymorphisms closely linked in the CYP1A1 gene: lack of association with susceptibility to lung cancer in a Finnish...
- 17
- 241
- 0
Báo cáo y học: "Serotonin transporter gene polymorphisms and brain function during emotional distraction from cognitive pdf
... and proposed to inform neuroimaging and genetics investigations of PTSD (reviewed in [49,50]) Our goal was to investigate the link between common variants of the serotonin transporter gene (including ... present findings in the broader context of neuroimaging and genetics findings observed in related neuropsychiatric disorders, particularly major depression and anxiety disorders There is increasing ... [1,2], including mood disorders [3], anxiety disorders [4-6], and schizophrenia [7] Whereas imaging genetics has generally relied on exploration of candidate gene effects, gene discovery has generally...
- 13
- 262
- 0
Báo cáo y học: "Association between IL-18 gene polymorphisms and biopsy-proven giant cell arteritis" potx
... participated in the acquisition and interpretation of data JLC participated in the acquisition and interpretation of data BF has been involved in the acquisition and interpretation of data and in revising ... ICM participated in the acquisition and interpretation of data SC has been involved in the acquisition and interpretation of data and in revising it critically for important intellectual content ... interleukin-18 gene in cardiovascular disease Circulation 2005, 112:643-650 39 Kretowski A, Mironczuk K, Karpinska A, Bojaryn U, Kinalski M, Puchalski Z, Kinalska I: Interleukin-18 promoter polymorphisms...
- 7
- 251
- 0
Báo cáo y học: "Surfactant gene polymorphisms and interstitial lung diseases" pptx
... understanding of the genetics of the underlying lung disease in general, and SP expression in particular, may be important in defining susceptibility to and progression of these conditions Genetics ... important candidate genes is examined in populations of unrelated affected individuals, and compared with prevalence in unrelated normal controls Genetic studies in interstitial lung disease Very ... alleles in the genes encoding TAP2, the CC chemokine receptor 2, the angiotensin-converting enzyme and vitamin D receptor [12] Polymorphisms in the fibronectin gene [13] and the HLA-DPB1*1301 allele...
- 7
- 246
- 0
Báo cáo y học: "Cerebrospinal fluid signs of neuronal damage after antiretroviral treatment interruption in HIV-1 infectio" docx
... 59 and for subject 6011 the inflection point showing the initial increase was delayed to 86 and 99 days In the two subjects with increases in NFL and more frequent measurements, the rise in plasma ... application of cerebrospinal fluid neopterin concentrations in HIV infection Pteridines 2004, 15:102-106 Tibbling G, Link H, Öhman S: Principles of albumin and IgG analyses in neurological disorders ... suggesting that immune activation was important in the neuronal injury and release of NFL in this setting While elevations in CSF neopterin were found in all the subjects with increased NFL and...
- 7
- 406
- 0
Báo cáo y học: " Effective inhibition of HCMV UL49 gene expression and viral replication by oligonucleotide external guide sequences and RNase P" pptx
... effective and specific inhibition of gene expression RNA-based EGSs have been expressed endogenously as transgenes in both bacteria and mammalian cells [12], and were effective in inhibiting the gene ... exogenous administration of DNA-based EGSs is highly efficient in inhibiting gene expression and viral growth Further understanding of how the functional groups in the nucleotides of an EGS interact ... EGS-based technology for gene- targeting applications in both basic research and clinical therapy of HCMV infections Competing interests The authors declare that they have no competing interests Authors'...
- 8
- 316
- 0
CORRELATING IRINOTECAN AND CAPECITABINE TREATMENT FOR COLORECTAL CANCER TO GENE EXPRESSION, POLYMORPHISMS, AND CLINICAL OUTCOMES
... treatment with capecitabine and irinotecan (CPT-11) combination followed by chemoradiation with capecitabine and finally surgery to improve response and decrease local recurrence Irinotecan and ... CES2 contain a small acyl and a large alcohol moiety (17) Relationship to Irinotecan and Capecitabine Irinotecan and Capecitabine are carbamate prodrugs, which require in vivo activation Irinotecan ... placed in a buffer, homogenized, and purified NAs were obtained with Qiagen kits RNA integrity was determined using the 2100 bioanalyzer (Agilent) and the RNA integrity number was determined using...
- 50
- 178
- 0
Evaluation of the impact of polymorphisms on candidate genes of allergic rhinitis and asthma on disease outcomes in the singapore population
... major genes regulating atopic diseases Candidate genes Positional candidate genes Identify candidate genes Determine functional relevance of polymorphisms in candidate genes Assess role of SNPs in ... are helpful in searching for genetic component in atopic diseases Family study and twin study are useful steps in determining whether atopy and atopic diseases have genetic components, and segregation ... of SNPs in disease gene in interaction with the environment Two aspects of research in gene function (In vivo and in vitro) Useful for understanding, prevention and therapy for atopic diseases...
- 274
- 363
- 0
Coronary Artery Disease – Current Concepts in Epidemiology, Pathophysiology, Diagnostics and Treatment Edited by David Gaze pptx
... These findings are cause for concern, indicating that decades of progress in reducing deaths from CAD appear to be stalling Changes in lifestyle factors in the young (increasing obesity and sedentary ... age and sex, in England in 2008 Chronic stable angina 4.1 Defining chronic stable angina The evaluation of epidemiologic data concerning chronic stable angina is more challenging than assessing ... in areas where CAD is in decline, as such CAD will remain the leading cause of death worldwide Myocardial infarction 3.1 Defining myocardial infarction Acute myocardial infarction (AMI) remains...
- 286
- 424
- 0
báo cáo hóa học: " Urinary and sexual outcomes in long-term (5+ years) prostate cancer disease free survivors after radical prostatectomy" ppt
... were fixed in formalin, coated with India ink, weighed, and serially sectioned, staged, and graded according to the 2002 American Joint Committee on Cancer (AJCC) staging system Follow-up included ... corresponding bother For this analysis, we focused on subject urinary and sexual function (UF and SF) and urinary and sexual bother (UB and SB) Responses were scored from to 100, with a higher score indicating ... disorders), subsequent to RP, are determinant on urinary incontinence After NS-RP without HT the correlation between SF and SB is maintained for years, after which function and bother appear to have divergent...
- 8
- 318
- 0
Báo cáo y học: "CTLA-4 +49A/G and CT60 gene polymorphisms in primary Sjögren syndrome" docx
... autoimmune diseases (reviewed in [1]) Both polymorphisms are in linkage disequilibrium, which warrants haplotype analysis in studies of CTLA-4 polymorphisms The CT60 G allele has been reported to increase ... with pSS and 156 controls [3] The aim of our study was to investigate in a large case-control study whether CTLA-4 CT60 and/ or +49A/G SNPs were involved in genetic predisposition to pSS in French ... +49A/G polymorphisms in a replication study The geographical origin and the clinico-biological characteristics of the patients in this second cohort were the same as those in the first In this...
- 3
- 295
- 0
Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc mở máy động cơ rôto dây quấn hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008