hiv 1 proteins and antiretroviral drug therapy in hiv 1 induced oxidative stress
báo cáo khoa học: " A situational picture of HIV/AIDS and injection drug use in Vinnitsya, Ukraine" pptx
... 19 99, 13 (7):7 41- 749 Hamers FF, Batter V, Downs AM, Aliz J, Cazein F, Brunet JB: The HIV epidemic associated with injecting drug use in Europe: geographic and time trends AIDS 19 97, 11 (11 ) :13 65 -13 74 ... problem of drug abuse and HIV/ AIDS in this city 16 18 19 20 21 22 23 24 25 References Ball AL, Rana S, Dehne KL: HIV prevention among injecting drug users: responses in developing and transitional ... International Clinical, Operational and Health Services Research and Training Award IDU – Injection Drug Use IDUs – Injection Drug Users IDU-RAR – Rapid Assessment and Response in Injection Drug Use...
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Báo cáo khoa học: Identification and characterization of 1-Cys peroxiredoxin from Sulfolobus solfataricus and its involvement in the response to oxidative stress pdf
... 2, pUC19 and 10 mM DTT; lane 3, pUC19 and lM FeCl3; lane 4, pUC19, 10 mM DTT, and lM FeCl3; lane 5, pUC19, 10 mM DTT, lM FeCl3, and 50 lgÆmL )1 rBcp2; lane 6, pUC19, 10 mM DTT, lM FeCl3, and 50 ... caused by oxidative stress conditions, are important in determining the level of Bcp2 protein Similar results are observed for genes and related proteins involved in oxidative stress in other microrganisms ... Aeropyrum pernix APE2278 [10 ] and Pyrococcus horikoshii PH1 217 [11 ,12 ] have A H2O 1- Cys Prx 1- Cys Prx H2O2 Sp OH 722 Identification of the bcp2 gene encoding putative peroxiredoxin The analysis of the...
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Báo cáo khoa học: The silencing of adenine nucleotide translocase isoform 1 induces oxidative stress and programmed cell death in ADF human glioblastoma cells doc
... F E than in ANT2 siRNA- and Scramble-transfected cells, 72 h after transfection (Fig 6E) 10 1 FL2-H 10 2 10 3 10 1 LQ: 3% 10 0 10 1 FL2-H 10 2 10 3 UQ: 97% LQ: 97% 10 0 10 2 10 3 FL1-H 10 4 10 1 D 10 0 Fig ... show oxidative damage as a consequence of ANT1-silencing According to this hypothesis, we found that ANT1 siRNA-treated cells 10 2 FL1-H 10 3 10 4 10 3 10 4 UQ: 86% 10 3 10 4 LQ: 14 % 10 0 10 1 10 2 FL1-H ... G (19 96) Coordinate expression of nuclear and mitochon- 2866 14 15 16 17 18 19 20 21 22 23 24 25 drial genes involved in energy production in carcinoma and oncocytoma Biochim Biophys Acta 13 16,...
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báo cáo hóa học:" Correlation between expression of p53, p21/WAF1, and MDM2 proteins and their prognostic significance in primary hepatocellular carcinoma" docx
... ≥20 ng/ml 18 1 16 5 16 18 1 75 10 6 18 1 61 120 18 1 14 5 36 18 1 16 1 20 18 1 14 3 38 18 1 52 12 9 p53 positive n (%) P value p 21/ WAF1 positive n (%) P value MDM2 positive n (%) P value 11 7(70.9) 11 (68.8) 0.857 ... p 21/ WAF1, and MDM2 expression in HCC tissues were 70.7% (12 8 /18 1), 33 .1% (60 /18 1), and 52.5% (95 /18 1), respectively Positive proportions of p53, p 21/ WAF1, and MDM2 expression in the corresponding ... also ambiguous [10 ,11 ,15 ] However, few studies pertaining to the expression of the proteins p53, p 21/ WAF1, and MDM2 in HCC cases have reported different results [11 ,16 ] We determined the expression...
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Báo cáo khoa học: "Early prediction of response to radiotherapy and androgen-deprivation therapy in prostate cancer by repeated functional MRI: a preclinical study" pptx
... , Schering, Berlin, Germany) was inserted into the tail vein Dynamic T1-weighted (T1W) imaging was acquired by performing 20 minutes of dynamic fast spoiled gradientrecalled (FSPGR) imaging after ... when using a BPNN, care should also be taken when training the network, in order not to under- or overtrain it [25] Since our RMSE function (Figure 4A) from training, testing and validating the ... Roentgenol 2008, 19 0 :11 80 -11 86 Kurhanewicz J, Vigneron D, Carroll P, Coakley F: Multiparametric magnetic resonance imaging in prostate cancer: present and future Curr Opin Urol 2008, 18 : 71- 77 Lisboa...
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báo cáo khoa học: "Development of PEGylated PLGA nanoparticle for controlled and sustained drug delivery in cystic fibrosis" pptx
... leading to decrease in LPS induced oxidative stress as seen by NOS2 immunostaining (Fig 10 ) The PLGAPEG PS3 41 treated mice exhibited significant decrease (day 3) in LPS induced NFB expression and ... localization, and decline in number of inflammatory, macrophages (Mac-3 + ) and neutrophil (NIMP-R14 + ), cells (Fig 11 ) H&E staining verified the rescue from PaLPS induced inflammation by PLGA-PEGPS3 41 ... mediated PS-3 41 drug delivery in controlling Pa-LPS induced lung disease in CF mice We verified that PLGA-PEGPS3 41 treatment controls PaLPS induced NFB protein levels (Fig 9), indicating towards...
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Báo cáo y học: "Anti-inflammatory potential of a malleable matrix composed of fermented whey proteins and lactic acid bacteria in an atopic dermatitis model" pot
... and Engineering Research Council of Canada (NSERC) Strategic Grant STP 246405 -1 JB was a Ph.D scholar of Fond de recherche en santé du Québec (FRSQ) 22 References 26 10 11 12 13 14 15 16 17 18 ... pro-Th1 cytokines and an increasing in regulatory cytokine IL -10 production [9 ,11 ] More specifically, LF exerts its anti-inflammatory effect during mouse atopic contact dermatitis (ACD) by reducing ... whey proteins: role of glutathione Clin Invest Med 19 91, 14 :296-309 Kent KD, Harper WJ, Bomser JA: Effect of whey protein isolate on intracellular glutathione and oxidant -induced cell death in...
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Báo cáo y học: " Mutations in the E2-PePHD region of hepatitis C virus genotype-3a and correlation with response to interferon and ribavirin combination therapy in Pakistani patients" pptx
... R15 S15 E15 Q15 H10 P15 L15 L15 H14 S15 T15 T14 Q5 R1 A1 Afzal et al Virology Journal 2 010 , 7:377 http://www.virologyj.com/content/7 /1/ 377 Page of Table Amino acid sequences of PePHD domain in ... L L H S T T R14 S14 E14 L9 H14 P14 L14 L14 H14 S14 T14 T14 Q5 Table PePHD amino acid substitutions in base line samples of rapid responders to interferon plus ribavirin therapy (15 variants) ... MM: Inhibition of the interferon-inducible protein kinase PKR by HCV E2 protein Science 19 99, 285(5424) :10 7 -11 0 doi :10 .11 86 /17 43-422X-7-377 Cite this article as: Afzal et al.: Mutations in the...
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Báo cáo y học: "Serum levels of autoantibodies against C-reactive protein correlate with renal disease activity and response to therapy in lupus nephritis" pps
... Mann-Whitney 30.5 (13 .1) 35.0 (11 .6) NS 27.0 (8.2) 35 .1 (12 .7) NS Female 16 18 29 Male 3 Caucasian 16 17 28 Iranian Caucasian 3 Age (years) Gender Ethnicity Iraqi Caucasian 1 Asian 1 Creatinine (μmol/l) ... renal BILAG 10 11 12 13 14 Competing interests The authors declare that they have no competing interests 15 Authors' contributions CS contributed to the original idea, laboratory work, interpretation ... autoantibodies against C-reactive protein and other acute phase proteins Clin Chim Acta 2007, 378 :13 -23 Marnell L, Mold C, Du Clos TW: C-reactive protein: ligands, receptors and role in inflammation Clin Immunol...
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Báo cáo y học: "Optical tomographic imaging discriminates between disease-modifying anti-rheumatic drug (DMARD) and non-DMARD efficacy in collagen antibody-induced arthritis" pptx
... http://arthritis-research.com/content /12 /3/R105 Day Day 15 20 Fluorescence (pmol) 18 16 14 18 16 14 ns 10 # ** 20 Control Vehicle Prednisolone P38 MAPKi Celecoxib 12 ** Page 11 of 13 * 12 10 ** 4 2 0 Figure Tomographic imaging ... Louis, MO 63 017 , USA 1VisEn Page 12 of 13 Received: March 2 010 Revised: 29 April 2 010 Accepted: 28 May 2 010 Published: 28 May 2 010 ArthritisPeterson etTherapy 2 010 , 12 :R105 © 2 010 Research & ... was injected in additional studies on both day and day 14 At Page of 13 the time of imaging (24 h post agent injection), mice were anesthetized using an intraperitoneal injection of ketamine (10 0...
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Báo cáo y học: "Diagnostic value and clinical laboratory associations of antibodies against recombinant ribosomal P0, P1 and P2 proteins and their native heterocomplex in a Caucasian cohort with systemic lupus erythematosus" pot
... 10 0% specificity cutoff 11 .9 (11 .5) 11 .3% (9 .1) 49 .1% (9.0) 31. 3% (16 9.0) 13 3.2% 14 0.7%b 16 1.8% 16 0.8% Maximum sum of specificity and sensivity b 8.9% (14 .7) 11 .3% (17 .4) 12 .3% (7.9) 11 8.2% 11 7.9% ... 31. 5 0.825 36.4 29.4 0.526 17 .4 33 .1 0 .15 1 29.6 31. 1 1. 000 Cyclophosphamide,c % 8. 81 6.89 9.23 1. 000 12 .1 7.94 0.4 91 18.8 7.75 0 .15 5 11 .1 8.33 0.708 Mycophenolate mofetil,c % 20.5 20.7 19 .7 1. 000 ... Identification and chemical synthesis of a ribosomal protein antigenic Barkhudarova et al Arthritis Research & Therapy 2 011 , 13 :R20 http://arthritis-research.com/content /13 /1/ R20 10 11 12 13 14 15 16 17 18 ...
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Autocrine growth hormone (hGH) and chemotherapeutic drug resistance in mammary carcinoma cells 2
... 4 .1. 10B……………………………………………………………………… 13 5 xi Fig 4 .1. 11A……………………………………………………………………… 13 8 Fig 4 .1. 11B …………………………………………………………………… 13 9 Fig 4 .1. 11C ……………………………………………………………………… .14 0 Fig 4 .1. 12 ………………………………………………………………………… .14 2 Fig 4.2.1A………………………………………………………………………… .14 7 ... activation and recruitment domain Cyclin-dependent kinase Chinese hamster ovary cells Cyclin kinase inhibitor CCAAT/enhancer binding proteins Death effector domain Death domains Death-inducing signaling ... alpha interferon IGF -1 Insulin-like growth factor -1 IGFBPs IGF binding proteins JNK/SAPK c-Jun N terminal protein kinase /Stress activated protein kinase LAP Liver activating protein LB Luria-Bertani...
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Autocrine growth hormone (hGH) and chemotherapeutic drug resistance in mammary carcinoma cells 3
... proliferation within the canine mammary gland, acting in an autocrine/paracrine manner In the canine 15 mammary gland, a Pit -1- independent mechanism for progestin/progesterone induced mammary GH ... GHR and several other proteins involved in GH signal transduction, including non-receptor (c-Src, c-Fyn, FAK) and receptor kinases (EGF) (Carter-Su and Smit 19 98) and other proteins including ... chemotherapeutic drugs, including redox-cycling agents, 47 alkylating agents and platinum-based drugs in tumors and cancer cell lines (Godwin et al 19 92; Hayes and Strange 19 95; Lewis et al 19 88; Russo...
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Báo cáo khoa học: Photodynamic treatment and H2O2-induced oxidative stress result in different patterns of cellular protein oxidation ppt
... FEBS 2003 10 11 12 13 14 15 16 17 18 19 20 21 22 23 Protein oxidation on photodynamic treatment (Eur J Biochem 270) 4865 kinases in human skin cells by 5-aminolevulinate-photodynamic therapy Cancer ... are shown in (A) and (B) Silver staining is shown in (C) and (D) in blue superimposed with the spots of oxidized proteins shown in red Protein labels: 1, a-tubulin; 2, b-tubulin; 3, actin; 4, PDI; ... ROS-mediated toxicity [11 ,12 ,26] including singlet oxygen-mediated toxicity [10 ,26] Oxidation of cellular proteins in response to PDT may be crucially involved in the mechanisms of PDTinduced cell death...
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Báo cáo khoa học: "Comparative study of PM2.5 - and PM10 - induced oxidative stress in rat lung epithelial cells" pptx
... observed in the groups of three concentration of PM2.5 and PM10 (5, 1, 0.2 µg/cm2) However, Nrf-2 protein induced by PM2.5 was higher than PM10 (Fig 13 ) 16 Jin-Hyuk Choi et al Fig 10 RT-PCR ... cancer therapy Int J 18 Jin-Hyuk Choi et al Biochem Cell Biol 2000, 32, 15 7 -17 0 19 Monn C, Becker S Cytotoxicity and induction of proinflammatory cytokines from human monocytes exposed to fine(PM2.5) ... containing PM10 and the other filter containing PM2.5 Preparation and extraction of filters Teflon filters were baked for h at 10 0oC and transferred into 50 ml conical tube with the particles facing...
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Báo cáo y học: "β Treatment with recombinant interferon-β reduces inflammation and slows cartilage destruction in the collagen-induced arthritis model of rheumatoid arthritis" ppt
... diluted in PBS containing 1% BSA and 10 % normal mouse serum at the following dilutions: anti-CD3 (1: 20), anti-CD22 (1: 20), anti-TNF-α (1: 10), anti-IL -1 (1: 60), anti-IL-6 (1: 60), anti-IL -10 (1: 80), ... activity of interleukin-4 and interleukin -10 in suppression of inflammation and joint destruction in rheumatoid arthritis Arthritis Rheum 20 01, 44:3 -12 39 Maini R, Paulus H, Breedveld F, Moreland LW, ... previously investigated in CIA in mice by IFN-β gene therapy [11 ] Fibroblasts from DBA /1 mice were infected with a retrovirus expressing murine IFN-β and were injected intraperitoneally into CIA...
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Báo cáo khoa học: Fasting-induced oxidative stress in very long chain acyl-CoA dehydrogenase-deficient mice pdf
... Spontaneous oxidative stress and liver tumors in mice lacking methionine adenosyltransferase 1A FASEB J 16 , 12 92 12 94 Oxidative stress in VLCAD KO mice 26 Robertson G, Leclercq I & Farrell GC (20 01) Nonalcoholic ... fasting on plasma lipids, lipoproteins and apolipoprotein B in 12 physicians participating in a hunger strike: an observational study Isr Med Assoc J 2, 215 – 219 15 Savendahl L & Underwood LE (19 99) ... RNeasy mini kit (Qiagen, Hilden, Germany) Forward and reverse primers for b-actin (BC138 614 ), AOX (NM_ 015 729.2) and CYP4A1 (NM_ 010 011 .3) were designed with the fastpcr program (R Kalendar, Institute...
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Báo cáo khoa học: Cyclosporin A-induced oxidative stress is not the consequence of an increase in mitochondrial membrane potential doc
... increases in JC -1 fluorescence in response to either CsA or its analogs in GLC4 cells Inhibition of P-glycoprotein by CsA and its analogs, including NIM 811 , resulted in significant increases in JC -1 fluorescence ... Cyclosporin A -induced oxidative stress M van der Toorn et al calcineurin therefore play a role in cyclosporin A -induced oxidative stress and disturbed Ca2+ homeostasis Immunosuppressive ... Cyclosporin A -induced oxidative stress M van der Toorn et al Fig Effects of CsA (10 lM), NIM 811 (10 lM) and PSC833 (10 lM) in GLC4 cells without expression of P-glycoprotein (GLC4) and GLC4 cells...
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