herpes simplex virus type 1 derived recombinant and amplicon vectors
Báo cáo sinh học: "A dual function fusion protein of Herpes simplex virus type 1 thymidine kinase and firefly luciferase for noninvasive in vivo imaging of gene therapy in malignant glioma" ppsx
... vector-producing cells Nat Med 19 97, 3 :13 54 -13 61 Page 11 of 13 (page number not for citation purposes) Genetic Vaccines and Therapy 2004, 2:7 10 11 12 13 14 15 16 17 18 19 20 21 22 Shand N, Weber F, Mariani ... advantages The much greater sensitivity of BLI as compared to PET (10 -15 – 10 -17 vs 10 -11 – 10 -12 mole/L of reporter probe are detectable, [13 ]) in combination with very low background signals render ... methods: (1) the technique is very sensitive (possibly 10 -15 – 10 -17 mole of luciferase/L are detectable in vivo, [13 ]) and detects tumor cells at a stage where radiography and PET cannot [14 ,15 ],...
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Báo cáo hóa học: " Herpes simplex virus type-1(HSV-1) oncolytic and highly fusogenic mutants carrying the NV1020 genomic deletion effectively inhibit primary and metastatic tumors in mice" pptx
... herpes simplex viruses against renal cell carcinoma Int J Oncol 2007, 30 :15 61- 1567 Page of 10 (page number not for citation purposes) Virology Journal 2008, 5:68 10 11 12 13 14 15 16 17 18 19 20 21 ... alphaherpesvirus entry J Virol 2000, 74 :11 773 -11 7 81 Even DL, Henley AM, Geraghty RJ: The requirements for herpes simplex virus type cell-cell spread via nectin -1 parallel those for virus entry Virus ... Dis 19 90, 16 2: 313 -3 21 Cadoz M, Seigneurin JM, Mallaret MR, Baccard C, Morand P: Phase I trial of R7020: A live attenuated recombinant herpes simplex virus (HSV) candidate vaccine In Program and...
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Báo cáo y học: "Subacute herpes simplex virus type 1 encephalitis as an initial presentation of chronic lymphocytic leukemia and multiple sclerosis: a case report" doc
... HBcAb (IgM) and HBsAg Non-reactive HC Ab Non-reactive LCMV IgG and IgM Ab titer
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Báo cáo khoa học: " Herpes simplex virus type 1 and normal protein permeability in the lungs of critically ill patients: a case of low pathogenicity" docx
... reactivation of human herpesvirus variant A occurs in critically ill immunocompetent hosts J Infect Dis 2002, 18 5 :11 0 -11 3 18 Ramsey PG, Fife KH, Hackman RC, Meyers JD, Corey L: Herpes simplex virus pneumonia ... AA: T cells and the regulation of herpes simplex virus latency and reactivation J Exp Med 2000, 19 1 :14 55 -14 57 24 Oberholzer A, Oberholzer C, Moldawer LL: Sepsis syndrome: understanding the role ... Respir Dis 19 82, 12 6: 416 - 419 Porteous C, Bradley A, Hamilton DNH, Ledingham IM, Clements GB, Robinson CG: Herpes simplex virus reactivation in surgical patients Crit Care Med 19 84, 12 :626-628...
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Báo cáo sinh học: " Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1" pot
... against Page 13 of 15 (page number not for citation purposes) Virology Journal 2005, 2:56 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 genital herpes simplex virus type infection ... with 51Cr and incubated with BALB/c, BALB/c scid, and NOD scid spleen WBCs in round bottom 96-well plates for hours at 37°C at effector : target ratios of 10 0 :1, 50 :1, 25 :1, 12 .5 :1, and 6.25 :1 (n ... activity J Exp Med 19 83, 15 7(5) :15 44 -15 61 Fitzgerald PA, Mendelsohn M, Lopez C: Human natural killer cells limit replication of herpes simplex virus type in vitro J Immunol 19 85, 13 4(4):2666-2672...
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báo cáo hóa học: " A role for DNA-dependent activator of interferon regulatory factor in the recognition of herpes simplex virus type 1 by glial cells" pot
... in herpes simplex encephalitis N Engl J Med 19 86, 314 :14 4 -14 9 34 Kimberlin DW: Management of HSV encephalitis in adults and neonates: diagnosis, prognosis and treatment Herpes 2007, 14 :11 -16 ... infection of herpes simplex virus type J Immunol 19 95, 15 5 :13 26 -13 33 43 Esiri MM, Drummond CWE, Morris CS: Macrophages and microglia in HSV1 infected mouse brain J Neuroimmunol 19 95, 62:2 01- 205 44 ... macrophages is mediated via the MDA5/MAVSdependent and MDA5/MAVS/RNA polymerase III-independent pathways J Virol 2 010 , 84 :11 350 -11 358 Page 12 of 12 doi :10 .11 86 /17 42-2094-8-99 Cite this article as: Furr...
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Báo cáo hóa học: " Herpes Simplex Virus Type 1 Us3 Gene Deletion Influences Toll-like Receptor Responses in Cultured Monocytic Cells" pdf
... moi R70 41 moi HSV -1 (KOS) moi HSV -1 (KOS) moi 10 d120 moi HSV -1 (F) moi HSV -1 (F) moi R7306 moi R7306 moi R70 41 moi R70 41 moi HSV -1 (KOS) moi d120 moi d120 moi uninfected 10 10 0 d120 moi 10 0 uninfected ... HSV -1 (KOS) moi HSV -1 (F) moi HSV -1 (F) moi R7306 moi R7306 moi R70 41 moi R70 41 moi HSV -1 (KOS) moi HSV -1 (KOS) moi d120 moi d120 moi uninfected 10 10 00 d120 moi 10 0 10 000 d120 moi 10 00 uninfected ... presentation Nature 19 95, 375: 415 - 418 Koyama AH, Adachi A: Induction of apoptosis by herpes simplex virus type J Gen Virol 19 97, 78(Pt 11 ):2909-2 912 Aubert M, Blaho JA: The herpes simplex virus type regulatory...
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báo cáo hóa học:" Re-evaluating the role of natural killer cells in innate resistance to herpes simplex virus type 1" pot
... against Page 13 of 15 (page number not for citation purposes) Virology Journal 2005, 2:56 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 31 genital herpes simplex virus type infection ... with 51Cr and incubated with BALB/c, BALB/c scid, and NOD scid spleen WBCs in round bottom 96-well plates for hours at 37°C at effector : target ratios of 10 0 :1, 50 :1, 25 :1, 12 .5 :1, and 6.25 :1 (n ... activity J Exp Med 19 83, 15 7(5) :15 44 -15 61 Fitzgerald PA, Mendelsohn M, Lopez C: Human natural killer cells limit replication of herpes simplex virus type in vitro J Immunol 19 85, 13 4(4):2666-2672...
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Báo cáo khoa học: "Herpes simplex virus type 2 tegument protein UL56 relocalizes ubiquitin ligase Nedd4 and has a role in transport and/or release of virions" ppt
... and their components in the egress of enveloped RNA viruses Rev Med Virol 2009, 19 : 31- 45 Page 11 of 13 (page number not for citation purposes) Virology Journal 2009, 6 :16 8 10 11 12 13 14 15 16 ... gene transcript of herpes simplex virus type Virus Res 19 91, 19 :11 5 -12 6 http://www.virologyj.com/content/6 /1/ 168 32 33 34 35 36 37 38 39 40 41 42 43 44 45 46 47 48 49 50 51 52 53 Koshizuka T, ... extracellular 10 10 10 10 24 * 10 12 * ** ** 10 18 6 UL56Z UL56Zrev 10 10 10 18 6 UL56Z UL56Zrev 36 hours post infection 12 24 36 hours post infection Figure of UL566 Extracellular infectious viruses...
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báo cáo hóa học: " Reactive oxygen species drive herpes simplex virus (HSV)-1-induced proinflammatory cytokine production by murine microglia" ppt
... ** C 0 .1 10 0 + + + 0 0 U 012 4 ( M) 10 0 0 .1 10 U 012 6 ( M) 0 10 HSV - - - + + + + 0 .1 10 0 + + + 0 0 .1 10 + + + 0 .1 10 0 + + + 0 0 .1 10 + + + 1. 4 ** 1. 2 ** CCL2 (ng/ml) 1. 4 1. 0 1. 2 †† 1. 0 †† 0.8 ... Page of 1. 0 ** TNF- (ng/ml) 0.8 0.8 † 0.6 0.6 †† 0.4 †† 0.2 0.0 16 0 B 0 U 012 4 ( M) 10 0 0 .1 10 U 012 6 ( M) 0 10 + + + HSV - - - + 12 0 ** (pg/ml) IL -1 0 .1 10 0 + + + 80 0 0 .1 10 + + + ** 10 0 12 0 †† ... M) 10 0 SB203580 ( M) 0 10 HSV - - - + 0.4 0.0 0 .1 10 0 + + + 0 0 .1 10 + + + U 012 4 ( M) 10 0 U 012 6 ( M) 0 10 HSV - - - + 0 .1 10 0 + + + 0 0 .1 10 + + + Figure Involvement of p38 and p44/42 (ERK1/2)...
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Báo cáo y học: " HuR interacts with human immunodeficiency virus type 1 reverse transcriptase, and modulates reverse " pps
... HuR 96h B D1:siRNA D2:siRNA D4:infection D5:staining 16 0 14 0 12 0 10 0 80 60 40 20 H2O HuR -1 HuR-2 HuR-3 Ctrl siRNA C D 12 0 siRNA Ctrl siRNA HuR1 10 0 250 pcDNA3 pCMV-HuR 200 80 15 0 60 10 0 40 50 ... http://www.retrovirology.com/content/5 /1/ 47 A B C 20 wt 400000 16 AREmut 350000 14 300000 12 p24 (ng/ml) infectious particles/ng p24 18 10 250000 200000 15 0000 10 0000 50000 2 10 12 14 days post-infection WT ... http://www.retrovirology.com/content/5 /1/ 47 studies have reported the binding of HuR to the RNAs of various viruses, including HPV -1, HPV -16 , Herpesvirus saimiri and HCV [28, 31, 32, 41, 42] However, no interference of HuR with HIV-1...
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Báo cáo y học: " Identity of zinc finger nucleases with specificity to herpes simplex virus type II genomic DNA: novel HSV-2 vaccine/therapy precursors" pps
... of herpes simplex virus type J Virol 19 98, 72(3):2 010 -20 21 28 Roizman B: The structure and isomerization of herpes simplex virus genomes Cell 19 79, 16 :4 81- 494 29 Chou J, Roizman B: Herpes simplex ... primary and recurrent disease caused by herpes simplex virus (HSV) type using a genetically disabled HSV -1 J Infect Dis 19 94, 17 0 :11 00 -11 09 49 Perkins D, Pereira EF, Aurelian L: The herpes simplex virus ... against herpes simplex virus Curr Top Microbiol Immunol 19 92, 17 9 :13 7 -15 8 19 Whitley RJ: Prospects for vaccination against herpes simplex virus Pediatr Ann 19 93, 22:726-732 20 Stanberry LR: Herpes simplex...
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Tài liệu Báo cáo khoa học: Role for nectin-1 in herpes simplex virus 1 entry and spread in human retinal pigment epithelial cells docx
... mediates HSV -1 entry into RPE cells FITC stained CHO-HVEM RPE D Events B 11 4 A C 10 1 10 2 11 9 10 0 10 3 10 4 FITC stained CHO-nectin -1 Events RPE 10 0 10 1 10 2 FITC 10 3 10 4 Fig Expression of HSV -1 gD receptors ... Spear PG (19 98) A cell surface protein with herpesvirus entry activity (HveB) confers susceptibility to infection by mutants of herpes simplex virus type 1, herpes simplex virus type 2, and pseudorabies ... cells J Virol 79, 13 173 13 179 17 Tiwari V, Shukla SY, Yue BY & Shukla D (2007) Herpes simplex virus type entry into cultured human 5284 18 19 20 21 22 23 24 25 26 27 28 29 30 31 corneal fibroblasts...
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Báo cáo sinh học: " Persistent expression of chemokine and chemokine receptor RNAs at primary and latent sites of herpes simplex virus 1 infection" pptx
... (2.2–20) (1. 8–4.7) CCR5 12 (12 .3 12 .5) 11 (8.0 14 ) 20 (8.9–36) (4.8 11 ) 57 (22 11 0) (7.0 10 ) CCR6 (2.4–3.0) (1. 0–2.5) (1. 5–8.5) (0.3 11 ) (1. 0–5.0) 14 (1. 0–40) CCR7 24 (8.0–40) (3.0–6.5) 17 (13 – 21) 13 ... 10 d 30d 3d 10 d 30d CCR1 11 (9.2 12 ) 18 (13 –23) 20 (10 –26) (2.2–7 .1) 15 (9.0 19 ) (1. 7–7.0) CCR2 14 (9.2 19 ) 22 (11 –32) 14 (8 .1 24) (1. 5–4.2) 15 (11 19 ) (1. 3–4.4) CCR3 (1. 0–5.0) (2.0–5.0) (2.5–3.3) ... MIP -1 Eotaxin -1 (3.2–3.3) (5.0 12 ) (5 .1 5.7) 17 (10 –24) 10 (7.0 13 ) (1. 5–3.9) (1. 3–8.8) (1. 0–4.4) (4.9–9.0) 68 (25 11 1) 35 (4.0–67) (1. 1–3 .1) (2.2–2.4) 0.7 (0.4 1. 0) (2.9–6.5) 20 (11 –28) (1. 0–7.0)...
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Báo cáo khoa học: Viral entry mechanisms: cellular and viral mediators of herpes simplex virus entry potx
... & Roizman B (20 01) Herpes simplex virus infections Lancet 357, 15 13 15 18 Spear PG (2004) Herpes simplex virus: receptors and ligands for cell entry Cell Microbiol 6, 4 01 410 Campadelli-Fiume ... 11 12 13 14 15 References Shukla D & Spear PG (20 01) Herpesviruses and heparan sulfate: an intimate relationship in aid of viral entry J Clin Invest 10 8, 503– 510 Whitley RJ & Roizman B (20 01) ... papillomavirus type- 16 [13 ,14 ] Surfing is also shared by many additional herpesviruses, including cytomegalovirus and human herpesvirus-8 (V Tiwari & D Shukla, unpublished results) Exposure of HSV-1...
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Báo cáo " Isomeranzin against Herpes simplex virus in vitro from Clausena heptaphylla (Roxb.) W. & ARN.: Isolation, structure and biological assay " potx
... ( , cm -1, KBr) : 838, 10 28, 11 15, 12 50, 12 91, 13 94, 15 02, 16 08, 17 19, 2968 MS (m/z, CHCl3) : 2 61 [M +1] +, 260 [M+], 11 9 19 0 [M +1- COCH(CH3)2]+ 1H-NMR ( , ppm, CDCl3): 1. 21 [d, 6H, j = 6.93 Hz, ... CDCl3): 18 .42 (4’-C, 5’-C); 34.69 (1 -C); 40.88 (3’-C); 56 .12 (7 - OCH3); 10 7.26 (6-C); 11 1.95 (10 -C); 11 2. 91 (8-C); 11 2.97 (3-C); 12 7.55 (5-C); 14 3.80 (4-C); 15 3.20 (9-C); 16 0.44 (7-C); 16 0.97 ... ppm and doublet signals at 1. 21 ppm [-CH(CH3)2] Signal at 3.85 ppm (s, 3H) was assigned for - OMe protons Wavenumbers (cm -1) Figure 1: IR spectrum of isomeranzin (KBr) 19 0 13 1 71 260 89 10 3 51 175...
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Báo cáo sinh học: " Attenuation and efficacy of human parainfluenza virus type 1 (HPIV1) vaccine candidates containing stabilized mutations in the P/C and L genes" potx
... 6h HPIV1 wt rHPIV1-CR84G rHPIV1-CR84GHNT553A rHPIV1-C 17 0 rHPIV1-LY942A rHPIV1-CR84GHNT553ALY942A rHPIV1-CR84GL 17 10 11 rHPIV1-CR84G/ 17 0HNT553ALY942A rHPIV1-CR84G/ 17 0HNT553AL 17 10 11 Mean sum ... rHPIV1-C 17 0 rHPIV1-LY942A rHPIV1-CR84GHNT553ALY942A rHPIV1-CR84GL 17 10 11 rHPIV1-CR84G/ 17 0HNT553ALY942A rHPIV1-CR84G/ 17 0HNT553AL 17 10 11 Non-immune a Monkeys were immunized i.n and i.t with 10 6 ... 6.9 ± 1. 5 5.5 ± 1. 6 1. 0 ± 0.0 (0/4) 4.5 ± 0.9 3.4 ± 0.4 11 .8 ± 2.5 8 .1 ± 1. 3 7.5 ± 1. 4 1. 0 ± 0.0 (0/4) 5.0 ± 0.6 3.9 ± 0.5 14 .8 ± 1. 2 11 .0 ± 2.5 6.0 ± 1. 3 10 HPIV1 wt rHPIV1-CR84G rHPIV1-CR84GHNT553A...
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Báo cáo sinh học: " Oligomerization of the human immunodeficiency virus type 1 (HIV-1) Vpu protein – a genetic, biochemical and biophysical analysis" ppt
... the cytoplasmic domain J Virol 19 96, 70:2669-2673 Page 10 of 11 (page number not for citation purposes) Virology Journal 2007, 4: 81 10 11 12 13 14 15 16 17 18 19 20 21 22 Cohen EA, Terwilliger EF, ... HIV -1, vpu, and its 16 -kilodalton product Science 19 88, 2 41: 12 21- 1223 Bour S, Strebel K: The human immunodeficiency virus (HIV) type envelope protein is a functional complement to HIV type 1Vpu ... Med 20 01, 19 4 :12 99 -13 11 Klimkait T, Strebel K, Hoggan MD, Martin MA, Orenstein JM: The human immunodeficiency virus type 1- specific protein vpu is required for efficient virus maturation and release...
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Báo cáo sinh học: " The herpes simplex virus UL20 protein functions in glycoprotein K (gK) intracellular transport and virus-induced cell fusion are independent of UL20 functions in cytoplasmic virion envelopment" docx
... the LSU School of Veterinary Medicine to BIOMMED References 10 11 12 13 14 15 16 17 18 Roizman B, Knipe DM: Herpes Simplex Viruses and Their Replication In Fields Virology Volume Third edition ... receptors for alphaherpesvirus entry Virology 2000, 275 (1) :1- 8 Spear PG, Longnecker R: Herpesvirus entry: an update J Virol 2003, 77 (19 ) :10 179 -10 185 Mettenleiter TC: Herpesvirus assembly and egress J ... in herpes simplex virus type Virology 19 84, 13 2(2):368-376 Debroy C, Pederson N, Person S: Nucleotide sequence of a herpes simplex virus type gene that causes cell fusion Virology 19 85, 14 5 (1) :36-48...
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