growth preserved the normal surrounding liver tissue and prolonged survival time in the murine liver tumor model
Báo cáo khoa học: " Experimental concepts for toxicity prevention and tissue restoration after central nervous system irradiation" ppt
... chemokines, cytokines and growth factors play important roles in intra- and intercellular communication CNS radiotherapy induces the production of inflammatory cytokines and mediators such as tumor- necrosis-factor-α ... endothelial cells and increase of capillary density [72] However, even in theory finding the right dose, timing and maybe combination and sequence of different growth factors in an individual patient ... aspects of radiation necrosis of the brain and spinal cord Initial events are similar to those described in the pathogenesis section, including inflammatory changes and increased vessel permeability...
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High Degree of Adherence to Statin Therapy Among the Elderly Despite High Frequency of Side Effects doc
... reached The other statins marketed in Sweden, representing the remaining 17% of the market share, are atorvastatin, rosuvastatin, pravastatin, and fluvastatin Of these, atorvastatin is the most ... the two statins (simvastatin and atorvastatin) most commonly used in Sweden In all cases in this study, however, simvastatin was the primary medication at the beginning of treatment and shows excellent ... patients to adhere to the treatment and to receive the full benefits of statin therapy The aims of the present study were: • to investigate adherence and side effects of statin therapy in elderly patients...
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Báo cáo y học: " Comparison of side effects of oxytetracycline and talc pleurodesis: an experimental study." doc
... PTFE catheter into the left pleural space The presence of air in the pleural space was checked, and if any, it was evacuated by using a three-way stopcock, and then the catheter was removed The ... participated in the sequence alignment and drafted the manuscript All authors read and approved the final manuscript Page of Competing interests The authors declare that they have no competing interests ... anesthesia Microscopy Sections of the chest wall and both lungs were taken in the anteroposterior plane in the midlung zone including the mediastinal structures The entire ipsilateral lung, en...
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Báo cáo y học: "Separating therapeutic efficacy from glucocorticoid side-effects in rodent arthritis using novel, liposomal delivery of dexamethasone phosphate: long-term suppression of arthritis facilitates interval treatment" pot
... chains in these tissues are connected by 3hydroxypyridinium crosslinks, which become discharged and excreted as pyridinoline upon disintegration of collagen [19] Levels of urinary pyridinoline ... one joint per paw using a predefined arthritis index on a scale of (normal) to (ankylosis), resulting in a maximum arthritis index of 16 The incidence of arthritis in the used model protocol was ... (a) and the additional aqueous phase marker 3H-inuline was analysed The resulting 3H/14C ratio was plotted with respect to the initial ratio The constant ratio indicates high carrier integrity in...
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Applying side effects of anti fibrotic compounds to promote neovascularization for tissue engineering
... embryos and these induced changes in the subintestinal vessels (SIVs) 65,66 The SIVs develop in the ventral trunk of the zebrafish embryo, underneath the somites, and grow over the yolk These vessels ... stained for CD31 and vWF The vWF (red) and CD31 (green) staining were co-localized on the HUVECs in the co-culture, enabling visualization of their orientation and morphology In this instance, the ... 18 model for screening potential drugs for inducing neovascularization in tissue engineering and advanced wound healing technology This model would have the advantage of being simple, rapid and...
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Applying side effects of anti fibrotic compounds to promote neovascularization for tissue engineering 1
... 4.5 PHi Induced HIF-1α and VEGF 95 4.6 Zebrafish Angiogenesis 96 4.7 PHi Inhibited Collagen Biosynthesis in vitro and in vivo 99 4.8 Applications in Tissue Engineering: Pre-vascularizing PLLA ... of Using PHi in Tissue Engineering 105 CONCLUSIONS 108 REFERENCES 111 v SUMMARY (ABSTRACT) Neovascularization and fibrosis are two challenges in regenerative medicine and tissue engineering which ... limit the survival, viability and function of implanted tissue engineered constructs and biomaterials Slow neovascularization can compromise delivery of oxygen and nutrients to cells in the interior...
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Side Effects: Death - Confessions of a Pharma-Insider
... vaporized with the blows They wiped their faces and necks on their sleeves, turned around and got back on the bus The guy lay there, where they had discontinued the blows The woods were quiet The rest ... over and the noble hotels were like filleted, eviscerated fish I saw the numerous empty rooms and yet I was to spend the night in the cold and the rain Then I had the idea to book into one of the ... hotels and bail out of the window in the early morning But I didn’t wake up in the night – I was too exhausted and slept till late morning Since I had nothing left to lose, I slipped into my clothes...
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báo cáo hóa học:" Quality of life in colon cancer patients with skin side effects: preliminary results from a monocentric cross sectional study" pot
... sample In addiction we constructed the three scales' index - symptoms, functioning and emotional - using the mean of the total score of the scale and standardizing scores to 100 The mean of the ... items included in the scale and the scale scores are standardized to 100 [8] According with the literature, when missing data were less than 20% of the items included in a scale, missing value was ... of life over time Finally, considering the clinical conditions of patients included in this study (mainly metastatic and cancer) it was not considered feasible in our setting to administer both...
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Báo cáo hóa học: " Renal and neurological side effects of colistin in critically ill patients" docx
... calcineurin inhibitor, hyperbilirubinemia, and hypoalbuminemia The incidence of kidney injury increased with an increase in the number of risk factors Hypoalbuminemia also was identified as an independent ... PMH participated in design, coordination, and writing All authors read and approved the final manuscript Competing interests The authors declare that they have no competing interests 15 16 Received: ... mg/dL) in the other studies However, it is striking that the studies reporting the highest incidence of colistin-associated nephrotoxicity [18,20,22,27] used products containing 150 mg of “colistin...
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Báo cáo khoa học: "Effects of treatment of fresh rice straw on its nutritional characteristics" pps
... sieve In- sacco samples of g each were then taken into nylon bags in duplicates The pore size of the nylon bags was 37 µm and the inner size of the bag was cm x 12 cm The bags were incubated starting ... characteristics in a water bath for 24 hours and then underwent the same washing and drying procedures as the incubated bags Duplicate bags of each sample were similarly dried for determination of the DM ... one hour after the cattle were offered the morning meal The incubation times were 4, 8, 16, 24, 48, 72, and 96 hours After incubation, the bags with residues were taken out of the rumen, dipped...
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Báo cáo y học: "Extrapyramidal side effects and suicidal ideation under fluoxetine treatment: a case repot" pps
... contributions in drafting the manuscript and revising it critically for intellectual content KT contributed to the clinical evaluations and manuscript drafting XG and AD made substantial contributions in ... of Medicine, Budapest, Hungary Authors’ contributions CC made substantial contributions to the conception and design of the present study, and was also involved in drafting and revising the manuscript ... contributing factor to the emergence of suicidal Page of ideation during treatment with fluoxetine [19] In our case, parkinsonism and restlessness (but no akathisia) were prominent in the clinical...
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Báo cáo y học: "The opposite effects of fluvoxamine and sertraline in the treatment of psychotic major depression: a case report" potx
... fluvoxamine binds to sigma-1 receptors in the intact human brain at therapeutic doses [25], suggesting that sigma-1 receptors are involved in the active mechanisms of fluvoxamine [19] Interestingly, ... and TK contributed to the clinical and rating evaluations during the follow-up periods KH conceived of the study and participated in its study and coordination All authors read and approved the ... with fluvoxamine (150 mg) monotherapy was maintained, and her condition remained good At years after the disappearance of the delusions, the patient began overeating and oversleeping, as well...
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Báo cáo khoa học: "Prior surgical intervention and tumor size impact clinical outcome after precision radiotherapy for the treatment of optic nerve sheath meningiomas (ONSM)" docx
... of the lesion Tumor progression was determined by an increase in tumor size of more than 35% (product of the two orthogonal diameters) or any increase in tumor size on subsequent imaging examinations ... compression of the ONSM of normal tissue structures In the orbial region very small changes in normal tissue and tumor geometry can have a major impact on organ and nerve function due to the very narrow ... followed, and patients with remaining useful vision and no tumor progression have been observed in the past [13] One main risk associated with surgery is the often inevitable dissection of the vascular...
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Báo cáo y học: "Presence of the CYP2B6 516G T polymorphism, increased plasma Efavirenz concentrations and early neuropsychiatric side effects in South African HIV-infected patients" pptx
... concentrations of drugs are the most useful in assessing efficacy and toxicity of the drug The nighttime dosing of EFV results in difficulty obtaining trough doses The suggested therapeutic range of ... resulted in lowering of EFV concentrations towards the therapeutic range and an improvement in CNS related symptoms in the majority of these patients In our study, the median EFV concentration for the ... presence of the TT genotype and higher intra and extracellular EFV concentrations and between the presence of the single nucleotide polymorphism (SNP) and increased incidence of fatigue, mood and sleep...
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báo cáo khoa học: "A hospital-site controlled intervention using audit and feedback to implement guidelines concerning inappropriate treatment of catheterassociated asymptomatic bacteriuria" pptx
... Monitoring the success of the intervention We plan to monitor the success of the intervention as we proceed, which in itself is crucial to interpreting the outcomes and ultimately disseminating the ... administered before and after the intervention The intervention will begin in year We will distribute guidelines and definitions concerning ABU and CAUTI at both sites in the form of a diagnostic ... used during the second and third years of the study These study materials include the CAUTI diagnostic algorithm, the audit and feedback intervention and script, and the surveys to be administered...
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ENCYCLOPEDIA OF ENVIRONMENTAL SCIENCE AND ENGINEERING - CHEMICAL EFFECTS: see EFFECTS OF CHEMICALS; AIR POLLUTANT EFFECTS; POLLUTION EFFECTS ON FISH CHEMICAL TREATMENT: see PHYSICAL AND CHEMICAL TREATMENT OF WASTEWATERS potx
... cooling tower releases will cause salt deposition in the surrounding area The nature and extent must be determined and evaluated using intake water quality data, design information and mathematical ... retains the natural impurities inherent in the coal such as heavy metals, chlorides as well as organic compounds formed by the combustion of coal in the reactor Testing, as defined in rules and ... based on the Shell © 2006 by Taylor & Francis Group, LLC IGCC process, was built and started-up in Buggenum, in the Netherlands, in 1994 Since October 2001, the installation has been owned and operated...
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Báo cáo y học: "Anti-inflammatory effects of antidepressant and atypical antipsychotic medication for the treatment of major depression and comorbid arthritis: a case report" pdf
... medication indicates a significant change in symptom presentation with a decline in pain and depressive symptoms while the activity levels increased continuously Moreover, the findings in this case ... between Nov 2003 and Oct 2008 depending on DMARD and psychotropic medication The psychiatric intervention in Oct 2007 through the mood disorder clinic and the subsequent change in DMARD and psychotropic ... of quetiapine in major depression [6] In the follow-up consultations in the mood disorder clinic it became apparent that her depressive symptoms were continuously improving, and following a month...
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Báo cáo y học: " Relation between therapeutic response and side effects induced by methylphenidate as observed by parents and teachers of children with ADHD" pptx
... patient to the other, and the correlations of these side effects with therapeutic effects were not explored in previous studies MPH has been shown to block the dopamine (DA) and norepinephrine (NE) ... resulting in increased synaptic DA and NE concentration in different brain regions including the prefrontal cortex [22] This increased neurotransmitter concentration likely results in the modulation ... and the interaction between these two variables on the mean severity ratings for each of the 17 side effects Effect size (Cohen’s d) was also determined from the mean severity ratings and standard...
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Báo cáo y học: "Cytokine profile of autologous conditioned serum for treatment of osteoarthritis, in vitro effects on cartilage metabolism and intra-articular levels after injection" potx
... study, in the joint space With respect to the role of Il-1 signalling in OA, in the one human clinical study using recombinant IL-1ra as a treatment for OA, a single injection into the knee joint ... out the in vitro and in vivo experiments, analysed and interpreted the data and drafted the manuscript DS participated in design and coordination of the study and revised the manuscript WD was involved ... each incorporation time point Explants were then rinsed in plain culture medium during three 45-minute changes, and the culture of these explants was continued in isotope-free medium until the...
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Báo cáo y học: "Response to: Cytokine profile of autologous conditioned serum for treatment of osteoarthritis, in vitro effects on cartilage metabolism and intra-articular levels after injection – authors’ reply" ppt
... Therapy 2010, 12:411 http://arthritis-research.com/content/12/6/411 up ACS-based randomized controlled trials with full patient and observer blinding and with unconditioned serum as control in ... to whether this treatment merits registration Page of Abbreviations ACS, autologous conditioned serum; IL-1, interleukin-1; OA, osteoarthritis Competing interests The authors declare that they ... with persistent knee pain, with and without OA, reveal significant diffrences from asymptomatic subjects in systemic markers of inflammation suggesting differences in innate immunity Paper presented...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008 chỉ tiêu chất lượng 9 tr 25