... granulocyte colony- stimulating factor , granulocyte colony stimulating factor, recombinant”, “GCSF”, “filgrastim”, “lenograstim”, “sargramostim”, “pegfilgrastim”, granulocyte- macrophage colony- stimulating ... warranted Abbreviations CIs: confidence intervals; G -CSF: granulocyte- colony stimulating factor; GMCSF: granulocyte- macrophage colony stimulating factor; LPS: lipopolysaccharide; mHLA-DR: monocytic ... doi:10.1186/cc10031 Cite this article as: Bo et al.: Granulocyte- colony stimulating factor (GCSF) and granulocyte- macrophage colony stimulating factor (GM- CSF) for sepsis: a meta-analysis Critical Care...
Ngày tải lên: 14/08/2014, 07:21
... treatment of granulocyte- macrophage colony- stimulating factor (GM- CSF) Peptide peak intensities increased or decreased by the treatment of granulocyte- macrophage colony- stimulating factor (GM- CSF) m/z ... By contrast, granulocyte- macrophage colony- stimulating factor (GM- CSF) sustains the viability of neutrophils and activates their functions For example, GMCSF primes neutrophils via phosphorylation ... http://arthritis-research.com/content/11/1/R3 Figure Detection of trypsin digested peptides from granulocyte- macrophage colony- stimulating factor (GM- CSF) stimulated neutrophils by matrix-assisted Detection of trypsin digested...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo khoa học: "The combined effect of erythropoietin and granulocyte macrophage colony stimulating factor on liver regeneration after major hepatectomy in rats" pot
... uses of granulocyte- macrophage colony- stimulating factor (GM- CSF) Stem Cells 1994, 12(Suppl 1):229-239 discussion 239240 13 Rapoport AP, Abboud CN, DiPersio JF: Granulocyte- macrophage colonystimulating ... received EPO 500 IU/ kg, a GM- CSF group (n = 21) that received 20 mcg/kg of GM- CSF and an EPO+GMCSF group (n = 21) which received a combination of the above EPO, GM- CSF or normal saline were administered ... Abboud CN, DiPersio JF: Granulocyte- macrophage colonystimulating factor (GM- CSF) and granulocyte colony- stimulating factor (G -CSF) : receptor biology, signal transduction, and neutrophil activation...
Ngày tải lên: 09/08/2014, 03:21
Báo cáo y học: "Prolonged, granulocyte–macrophage colony-stimulating factor-dependent, neutrophil survival following rheumatoid synovial fibroblast activation by IL-17 and TNFalpha" doc
... from Sigma (St Louis, MO, USA) Recombinant human (rh) granulocyte macrophage colony- stimulating factor (GMCSF), rhIL-17A and rhTNFα were from Peprotech (London, UK), monoclonal anti-human GM- CSF ... CXCL8 ***** ****** IL-10 IL-15 Granulocyte macrophage colony- stimulating factor * ** Granulocyte colony- stimulating factor * ** * ***** CCL2 ***** CCL3 * *** * * ... (RASFIL-17/TNF) maintains neutrophil viability in part through the release of granulocyte macrophage colony- stimulating factor (GM- CSF) and via phosphatidylinositol-3-kinase-dependent and NF-κB-dependent...
Ngày tải lên: 09/08/2014, 10:23
Nghiên cứu công nghệ sản xuất granulocyte colony stimulating factor (g CSF) người tái tổ hợp để hỗ trợ điều trị bệnh giảm bạch cầu
... Chromatography G -CSF Granulocyte colony stimulating factor g -csf Gen mã hóa cho protein G -CSF G-CSFR Thụ thể protein G -CSF (G -CSF receptor) G-MCSF Granulocyte macrophage colony stimulating factor GMK Green ... (Fermentas) g-csfmE Lac Z NdeI g -csf Vector tái tổ hợp Chủng tái tổ hợp pB-GCSF Mô hình gen plasmid E.coli DH5α/pBGCSF Ghi Phụ lục 1.2.1 LacZ XhoI LacZ pG-GCSF hay pUC57-GCSF E.coli DH5α/pUC57GCSF Phụ ... GCSF thông qua vị trí III Kết G-CSFR bị dimer hóa hình thành phức hợp cấu trúc homodimer 2:2 (2G -CSF – 2G-CSFR) (Hình 5) Hình Cấu trúc phức hợp tương tác G -CSF G-CSFR 11 Ngoài ra, gắn kết G-CSF...
Ngày tải lên: 16/04/2014, 11:16
Báo cáo y học: "Effect of a structurally modified human granulocyte colony stimulating factor, G-CSFa, on leukopenia in mice and monkeys" docx
... Recombinant human granulocyte colony- stimulating factor: effects on normal and leukemic myeloid cells Science 1986, 232(4746):61-65 Panopoulos AD, Watowich SS: Granulocyte colony- stimulating factor: molecular ... Similar to that of GCSF, G-CSFa was effective in stimulating the recovery of white blood cells in the irradiated mice (Figure 4; Table 1) At 50 μg/ml concentration, G-CSFa, but not G -CSF, was able ... rate of NFS60 cells (Figure 3) G-CSFa was more potent in Figure A comparison of in vitro activity between G-CSFa and wild-type G -CSF Recombinant G-CSFa and G -CSF at indicated concentrations (10...
Ngày tải lên: 10/08/2014, 21:23
Báo cáo y học: "Induction of tumour necrosis factor receptor-expressing macrophages by interleukin-10 and macrophage colony-stimulating factor in rheumatoid arthritis" doc
... and macrophage colony- stimulating factor (M -CSF) (a) Induction of on monocytes stimulated with interleukin-10 (IL-10) and macrophage colony- stimulating factor (M -CSF) monocyte expression of M -CSF ... type of macrophages characteristic of RA It has been shown that IL-10 augments the macrophage colony- stimulating factor (M -CSF) -induced growth and differentiation of human monocytes, and macrophages ... Figure colony- stimulating factor (TNF-α)-mediated interleukin (IL)-1β and IL-6 production by normal monocytes pretreated with IL-10 and/or macrophage Tumour necrosis factor- α(M -CSF) colony- stimulating...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "NF-κB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony-stimulating factor" docx
... demonstrated that expression of NFATc1, a key transcriptional factor of osteoclastogenesis induced by macrophage colony- stimulating factor (M -CSF) and receptor activator of NF-κB ligand (RANKL) in a ... (DHMEQ) on expression of receptor activator of NF-κB ligand (RANKL) and of macrophage colony- stimulating factor (M -CSF) by fibroblast-like synovial cells obtained from patients with rheumatoid ... osteoclasts Peripheral blood monocytes were incubated in 96-well plates with macrophage colony- stimulating factor (M -CSF) , receptor activator of NF-κB ligand (RANKL), and the indicated concentrations...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "ranulocyte-macrophage colony-stimulating factor as an immune-based therapy in HIV infection" pptx
... controlled trial of granulocyte macrophagecolony stimulating factor during interruption of HAART AIDS 2003, 17(10):1487-1492 Deresinski SC: Granulocyte- macrophage colony- stimulating factor: potential ... of granulocyte- macrophage colony- stimulating factor (GM- CSF) on hepatitis B vaccination in haemodialysis patients J Viral Hepat 1996, 3(3):149-153 Carlsson T, Struve J: Granulocyte- macrophage colony- stimulating ... that GMCSF enhances the action of anti-retroviral drugs (ARVD) Impact of GM- CSF use in HIV infected individuals Effect of GM- CSF on plasma HIV RNA levels Few randomized controlled trials of GM- CSF...
Ngày tải lên: 11/08/2014, 10:23
Báo cáo khoa học: Site-directed enzymatic PEGylation of the human granulocyte colony-stimulating factor pptx
... enzyme (MTGase) derived from a variant of Streptoverticillium mobaraense The granulocyte colony- stimulating factor (G -CSF) was used as substrate It is a challenging case, because it contains 17 ... protein–protein interaction between G -CSF and MTGase (G -CSF closed-MTGase and G -CSF open-MTGase) None of the docking solutions that we obtained involved interactions of G -CSF with the enzyme active site, ... closed-MTGase–G -CSF and open-MTGase– G -CSF; Gln134-restrained docking means that we performed the docking protocol with the inclusion of ˚ distance restraints of A between the G -CSF Gln134 and...
Ngày tải lên: 16/03/2014, 00:20
Báo cáo Y học: Acceleration of granulocyte colony-stimulating factor-induced neutrophilic nuclear lobulation by overexpression of Lyn tyrosine kinase docx
... Demetri, G.D & Grin, J.D (1991) Granulocyte colonystimulating factor and its receptor Blood 78, 2791±2808 Murakami, H & Nagata, S (1998) Granulocyte colonystimulating factor In The Cytokine Handbook, ... lobulation (B) GM- I62M; (C) GM- Lyn; (D) GM- LynKN However, the G -CSF- induced thymidine incorporation of both the GM- Lyn and GM- LynKN cells appeared to be the same as the parental GM- I62M cells ... the granulocyte colonystimulating factor receptor Blood 88, 761±777 Fukunaga, R., Ishizaka-Ikeda, E., Seto, Y & Nagata, S (1990) Expression cloning of a receptor for murine granulocyte colonystimulating...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo khoa học: Rapamycin inhibits lipopolysaccharide induction of granulocyte-colony stimulating factor and inducible nitric oxide synthase expression in macrophages by reducing the levels of octamer-binding factor-2 doc
... Fowler KJ, Basu S, Zhan YF & Dunn AR (1994) Mice lacking granulocyte colony- stimulating factor have chronic neutropenia, granulocyte and macrophage progenitor cell deficiency, and impaired neutrophil ... endogenous granulocyte colony- stimulating factor formation Biol Chem 383, 1501–1517 12 Nishizawa M, Tsuchiya M, Watanabe-Fukunaga R & Nagata S (1990) Multiple elements in the promoter of granulocyte colony- stimulating ... (r-metHuG -CSF) : the first 10 years Blood 88, 1907–1929 95 Rapamycin inhibits LPS-induced G -CSF and iNOS expression Y.-Y Chou et al 32 Demetri GD & Griffin JD (1991) Granulocyte colonystimulating factor...
Ngày tải lên: 22/03/2014, 17:20
Báo cáo khoa học: "Granulocyte-colony stimulating factor producing rectal cancer" docx
... for G -CSF may become part of the treatment paradigm Abbreviations CRC: colorectal cancer; G -CSF: granulocyte- colony- stimulating factor; GM- CSF: granulocyte- macrophage colony stimulating factor; ... cell carcinoma producing granulocyte- colony- stimulating factor Ann Thorac Surg 2007, 83:308-310 Yamano T, Morii E, Ikeda J, Aozasa K: Granulocyte colony- stimulating factor production and rapid ... producing granulocyte- colony stimulating factor: a case report Cancer 1998, 82:2102-2111 Ikeda T, Ohgaki K, Miura M, Aishima S, Shimizu T, Maehara Y: Granulocyte- colony stimulating factor- producing...
Ngày tải lên: 09/08/2014, 07:21
Báo cáo y học: " Aggressive cutaneous vasculitis in a patient with chronic lymphatic leukemia following granulocyte colony stimulating factor injection: a case report" pot
... in this context with granulocytic colony- stimulating factor (G -CSF) treatment Cutaneous vasculitis was reported in less than one in 7000 of those treated with G -CSF, and was moderate to severe ... during G -CSF doi:10.1186/1752-1947-5-88 Cite this article as: El Husseiny and Mattar: Aggressive cutaneous vasculitis in a patient with chronic lymphatic leukemia following granulocyte colony stimulating ... day after lenograstin injection (Figure 6) CBCs (complete blood count) revealed haemoglobin: 10 gm/ dl, TLC 2000/ul(persistently) and platelet count 150,000/ul The immune screen for cryoglobulins,...
Ngày tải lên: 11/08/2014, 00:22
Báo cáo y học: " Anaplastic carcinoma of the pancreas producing granulocyte-colony stimulating factor: a case report" potx
... granulocyte- colony stimulating factor Hepatogastroenterology 2006, 53(72):957-959 Fukushima N, Sasatomi E, Tokunaga O, Miyahara M: A case of pancreatic cancer with production of granulocyte colony- stimulating ... secondary to treatment with G -CSF have been reported [13] G -CSF stimulates neutrophils and macrophages Cytotoxic superoxide from neutrophils and various growth factors from macrophages cause interstitial ... of the pancreas producing granulocytecolony stimulating factor, and confirmed with immuno- Asano S, Urabe A, Okabe T, Sato N, Kondo Y: Demonstration of granulopoietic factor( s) in the plasma of...
Ngày tải lên: 11/08/2014, 19:21
Báo cáo khoa học: "Monocyte deactivation in neutropenic acute respiratory distress syndrome patients treated with granulocyte colony-stimulating factor" ppt
... neutropenia, in the immunosuppression of neutropenic patients treated with granulocyte colonystimulating factor (G -CSF) and presenting septic ARDS The objective of our study was to find evidence ... Complete resection No Surgery No ARDS = acute respiratory distress syndrome; G -CSF = granulocyte colony- stimulating factor Page of (page number not for citation purposes) Critical Care Vol 12 No ... percentiles), numbers or percentages ARDS = acute respiratory distress syndrome; G -CSF = granulocyte colony- stimulating factor *P < 0.05 for neutropenic patients versus non-neutropenic patients using...
Ngày tải lên: 13/08/2014, 10:20
Xây dựng quy trình thử nghiệm hoạt tính rhg CSF (recombinant humangranulocyte colony stimulating factor) và mô hình khảo sát tác động của rhg CSF theo phác đồ điều trị
... thành ba loại: - G -CSF (Granulocyte- colony stimulating factor) - GM- CSF (Granulocyte macrophage- colony stimulating factor) - M -CSF (Macrophage- colony stimulating factor) Trong đó, G -CSF cytokine sản ... chuẩn LU(units/mg) G -CSF kiểm tra IU(units/mg) G -CSF kiểm tra = - IU(units/mg) G -CSF chuẩn (108) : : IU(units/mg) G -CSF kiểm tra LU(units/mg) G -CSF kiểm tra x 108 LU(units/mg) G -CSF chuẩn (pg/ml) ... định lượng mẫu G -CSF - Mẫu G -CSF chuẩn bị cho quy trình định lượng bao gồm: Mẫu G -CSF chuẩn (Leukocim) Mẫu G -CSF cần định lượng - Các mẫu G -CSF bảo quản PBS 40C - Các mẫu G -CSF pha loãng thành...
Ngày tải lên: 13/10/2014, 20:47
Khảo sát lên men, thu nhận, tinh chế và dung hợp Granulocyte Colony Stimulati factor (G-CSF) tái tổ hợp từ E. coli với Polyethylenglycol (PEG)
... G -CSF Granulocyte colony stimulating factor g -csf Gen mã hoá cho protein hG -CSF G-CSFR Thụ thể protein hG -CSF (hG -CSF receptor) G-MCSF Granulocyte macrophage colony stimulating factor IBs Inclusion ... tác G -CSF với thụ thể Thụ thể G -CSF (G -CSF receptor hay G-CSFR) (Hình 1.4) diện tế bào tiền thân tủy xương kích thích G -CSF G-CSFR gồm vùng có chức khác nhau: vùng tế bào để tương tác với G -CSF; ... tương tác G -CSF G-CSFR Hình 1.6 Con đường tín hiệu tế bào G -CSF gắn với G-CSFR Hình 1.7 Sự hoạt động biệt hóa tế bào máu G -CSF cytokine khác 11 Hình 1.8 Một số sản phẩm hG -CSF thương...
Ngày tải lên: 04/02/2015, 12:46
Báo cáo y học: "Neutrophil elastase downmodulates native GCSFR expression and granulocyte-macrophage colony formatio" pot
... relevance of NE-induced cleavage of the G-CSFR Page of 10 10 Abbreviations G -CSF: Granulocyte colony- stimulating factor; G-CSFR: granulocyte colonystimulating factor receptor; NE: neutrophil elastase; ... neutrophils in granulocyte colonystimulating factor receptor-deficient mice Immunity 1996, 5:491-501 McLemore ML, Poursine-Laurent J, Link DC: Increased granulocyte colonystimulating factor responsiveness ... cell mobilization by granulocyte colony- stimulating factor Blood 2001, 98:1289-1297 Levesque JP, Hendy J, Winkler IG, Takamatsu Y, Simmons PJ: Granulocyte colony- stimulating factor induces the...
Ngày tải lên: 11/08/2014, 08:22
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