macrophage colony stimulating factor csf 1
Báo cáo y học: " Granulocyte-colony stimulating factor (G-CSF) and granulocyte-macrophage colony stimulating factor (GM-CSF) for sepsis: a meta-analysis" pps
... ± 17 .4 15 3/90 G -CSF 18 .0 12 49.8 ± 6.4 11 /1 Placebo 15 .9 13 54.8 ± 5.7 9/4 25.0 12 49.5 8/4 Placebo 31. 5 56.5 4/2 GM -CSF 12 10 62 7/3 Placebo 10 46.5 6/2 G -CSF 24.3 ± 7.5 348 58.9 ± 17 .1 240 /10 8 ... G -CSF 22.5 ± 7.6 81 51. 0 ± 15 .1 45/36 Placebo parallel groups, centers GM -CSF 23.4 ± 8.2 21. 3 ± 6 .1 83 19 48.9 ± 16 .1 64.0 ± 13 .6 45/38 16 /3 Placebo 22.5 ± 6.6 19 63.3 ± 14 .2 15 /4 Placebo 15 .5 ... 36:964-966 Bo et al Critical Care 2 011 , 15 :R58 http://ccforum.com/content /15 /1/ R58 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 Schefold JC: Measurement of monocytic HLA-DR (mHLA-DR)...
Ngày tải lên: 14/08/2014, 07:21
Báo cáo y học: "Implication of granulocyte-macrophage colony-stimulating factor induced neutrophil gelatinase-associated lipocalin in pathogenesis of rheumatoid arthritis revealed by proteome analysis" doc
... 8 41. 1 2.6 Nuclei 792.5 0.3 Nuclei 1, 577.9 2.9 Cytoskeleton 1, 562.0 2.8 Cytoskeleton 1, 569.9 2.6 Cytoskeleton 1, 584.0 2.6 Cytoskeleton 1, 2 31. 8 2.6 Cytoskeleton 1, 810 .0 0.4 Cytoskeleton 2,064 .1 ... 89.0/5 .1 [Swiss-Prot:P55072] 4 51 1.6 95.0/5.5 Actinin 10 4.8/5.3 [Swiss-Prot:O43707] 540 1. 6 91. 0/5.4 Transglutaminase 77.3/5 .1 [Swiss-Prot:P 219 80] 2, 217 1. 5 29.5/5.6 Cathepsin D 44.5/6 .1 [Swiss-Prot:P07339] ... granulocyte -macrophage colony- stimulating factor (GM -CSF) Peptide peak intensities increased or decreased by the treatment of granulocyte -macrophage colony- stimulating factor (GM -CSF) m/z Ratio...
Ngày tải lên: 09/08/2014, 01:22
Báo cáo khoa học: "The combined effect of erythropoietin and granulocyte macrophage colony stimulating factor on liver regeneration after major hepatectomy in rats" pot
... rats Transplantation 89 :16 1 -16 8 12 Jones TC: Future uses of granulocyte -macrophage colony- stimulating factor (GM -CSF) Stem Cells 19 94, 12 (Suppl 1) :229-239 discussion 239240 13 Rapoport AP, Abboud ... Granulocyte -macrophage colonystimulating factor (GM -CSF) and granulocyte colony- stimulating factor (G -CSF) : receptor biology, signal transduction, and neutrophil activation Blood Rev 19 92, 6:43-57 14 ... growth factor receptors Cell 19 85, 43:269-276 doi: 10 .11 86 /14 77-7 819 -8-57 Cite this article as: Vassiliou et al., The combined effect of erythropoietin and granulocyte macrophage colony stimulating...
Ngày tải lên: 09/08/2014, 03:21
Báo cáo y học: "Induction of tumour necrosis factor receptor-expressing macrophages by interleukin-10 and macrophage colony-stimulating factor in rheumatoid arthritis" doc
... CD30 3 .13 1. 15 TNFSF 11 Tumour necrosis factor (ligand) superfamily, member 11 TRANCE 3.50 2. 01 TNFRSF11A Tumour necrosis factor receptor superfamily, member 11 a, activator of nuclear factor- κB ... interleukin -10 (IL -10 ) and macrophage colony- stimulating factor (M -CSF) (a) Induction of on monocytes stimulated with interleukin -10 (IL -10 ) and macrophage colony- stimulating factor (M -CSF) monocyte ... supported in part by grants-in-aid (16 590982/ 18 5 911 11) from the Ministry of Education, Science, Culture, and Technology of Japan References 10 11 12 13 14 15 16 Feldmann M, Brennan FM, Maini RN:...
Ngày tải lên: 09/08/2014, 08:22
Báo cáo y học: "NF-κB inhibitor dehydroxymethylepoxyquinomicin suppresses osteoclastogenesis and expression of NFATc1 in mouse arthritis without affecting expression of RANKL, osteoprotegerin or macrophage colony-stimulating factor" docx
... mice J Atheroscler Thromb 2006, 13 :308- 313 18 Lee S-K, Lorenzo J: Cytokines regulating osteoclast formation and function Curr Opin Rheumatol 2006, 18 : 411 - 418 19 Suzuki Y, Sugiyama C, Ohno O, ... for TNF-α-mediated joint destruction J Clin Invest 2002, 11 0 :14 19 -14 27 Teitelbaum SL: Bone resorption by osteoclasts Science 2000, 289 :15 04 -15 08 Boyle WJ, Simonet WS, Lacey DL: Osteoclast differentiation ... 31 32 33 34 loop peptide mimic blocks RANK ligand-induced signaling, bone resorption, and bone loss J Clin Invest 2006, 11 6 :15 25 -15 34 Khosla S: The OPG/RANKL/RANK system Endocrinology 20 01, 14 2:5050-5055...
Ngày tải lên: 09/08/2014, 10:21
Báo cáo y học: "ranulocyte-macrophage colony-stimulating factor as an immune-based therapy in HIV infection" pptx
... trial of granulocyte macrophagecolony stimulating factor during interruption of HAART AIDS 2003, 17 (10 ) :14 87 -14 92 Deresinski SC: Granulocyte -macrophage colony- stimulating factor: potential therapeutic, ... controlled clinical study AIDS 19 97, 11 (12 ) :14 53 -14 61 Scadden DT, Bering HA, Levine JD, Bresnahan J, Evans L, Epstein C, Groopman JE: Granulocyte -macrophage colony- stimulating factor mitigates the neutropenia ... after recombinant human granulocyte -macrophage colony- stimulating factor (rhGM -CSF) and a single dose of recombinant hepatitis B vaccine Vaccine 19 96, 14 (13 ) :11 99 -12 04 Hess G, Kreiter F, Kosters...
Ngày tải lên: 11/08/2014, 10:23
Nghiên cứu công nghệ sản xuất granulocyte colony stimulating factor (g CSF) người tái tổ hợp để hỗ trợ điều trị bệnh giảm bạch cầu
... Chromatography G -CSF Granulocyte colony stimulating factor g -csf Gen mã hóa cho protein G -CSF G-CSFR Thụ thể protein G -CSF (G -CSF receptor) G-MCSF Granulocyte macrophage colony stimulating factor GMK ... mã hóa G -CSF ngƣời (Phụ lục 1. 1) 1. 1 Nghiên cứu thiết kế gen mã hóa G -CSF thay đổi codon (Phụ lục 1. 1 .1) Dựa vào đặc điểm cấu trúc, chức tác dụng G -CSF, quy trình thiết kế gen mã hóa G -CSF thay ... kiểm chứng biểu protein G -CSF chủng P pastoris GS 115 /GCSF lai western blot với kháng thể kháng G -CSF 43 Hình 15 Kết kiểm chứng biểu protein G -CSF chủng P pastoris GS 115 /GCSF sau trình lên men...
Ngày tải lên: 16/04/2014, 11:16
Xây dựng quy trình thử nghiệm hoạt tính rhg CSF (recombinant humangranulocyte colony stimulating factor) và mô hình khảo sát tác động của rhg CSF theo phác đồ điều trị
... 1. 1 Nhân tố kích thích tạo dòng bạch cầu hạt G -CSF 1. 1 .1 Giới thiệu 1. 1.2 Chức protein G -CSF 1. 1.3 Ứng dụng protein G -CSF trị liệu 1. 1.4 Một số sản phẩm G -CSF ... tế bào Các CSF chia thành ba loại: - G -CSF (Granulocyte -colony stimulating factor) - GM -CSF (Granulocyte macrophage- colony stimulating factor) - M -CSF (Macrophage- colony stimulating factor) Trong ... 1. 2 Thử nghiệm sinh học G -CSF 10 1. 2 .1 Thử nghiệm sinh học in vitro 10 1. 2.2 Thử nghiệm sinh học in vivo 11 1. 3 Phương pháp thử nghiệm sinh học G -CSF in vitro 13 ...
Ngày tải lên: 13/10/2014, 20:47
Báo cáo khoa học: Site-directed enzymatic PEGylation of the human granulocyte colony-stimulating factor pptx
... respectively A 18 0 Gln1 31 Gln134 18 0 12 0 12 0 60 60 0 –60 –60 12 0 12 0 18 0 18 0 12 0 –60 60 12 0 18 0 12 0 –60 60 Phi 18 0 12 0 18 0 Phi Gln1 31 C Gln132 D 6744 18 0 12 0 12 0 60 60 0 Psi 18 0 The analysis ... the G -CSF molecule by MTGase enzyme C Maullu et al 44 .18 15 .66 22. 51 22.34 25.53 70 80.74 77 86 90 10 7 11 9 12 0 13 1 19 .32 12 . 81 48.65 14 .34 59.5 14 .62 69.65 13 4 32.57 14 5 15 8 17 3 28. 71 19.5 72.04 ... C-terminus 10 20 30 40 50 60 70 80 90 10 0 11 0 12 0 13 0 14 0 15 0 16 0 17 0 Residue Fig RMSFs of the G -CSF Ca atoms during the entire MD simulation The points corresponding to Gln1 31 and Gln134 RMSFs...
Ngày tải lên: 16/03/2014, 00:20
Báo cáo Y học: Acceleration of granulocyte colony-stimulating factor-induced neutrophilic nuclear lobulation by overexpression of Lyn tyrosine kinase docx
... S (19 93) Signal transduction mediated by growth 388 T Omura et al (Eur J Biochem 269) 10 11 12 13 14 15 16 17 18 19 20 21 hormone receptor and its chimeric molecules with the granulocyte colony- stimulating ... 10 5 cellsámL )1 in medium containing no factor, 15 0 UámL )1 mouse G -CSF, or 45 UámL )1 mouse IL-3 The medium was replenished every 2±3 days to maintain the cell density at (1 5) ´ 10 5 cellsámL )1 ... P.A (19 98) The Src-like tyrosine kinase Hck is activated by granulocyte colony- stimulating factor (G -CSF) and docks to the activated G -CSF receptor Biochem Biophys Res Commun 2 51, 11 7 12 3 Corey,...
Ngày tải lên: 17/03/2014, 17:20
Báo cáo khoa học: Rapamycin inhibits lipopolysaccharide induction of granulocyte-colony stimulating factor and inducible nitric oxide synthase expression in macrophages by reducing the levels of octamer-binding factor-2 doc
... granulocyte colony- stimulating factor formation Biol Chem 383, 15 01 15 17 12 Nishizawa M, Tsuchiya M, Watanabe-Fukunaga R & Nagata S (19 90) Multiple elements in the promoter of granulocyte colony- stimulating ... the granulocyte colony- stimulating factor gene in macrophages Mol Cell Biol 10 , 2002–2 011 14 Morrison DC & Ryan JL (19 87) Endotoxins and disease mechanisms Annu Rev Med 38, 417 –432 15 Cohen J (2002) ... 200 10 0 D LPS LPS + Rapa 500 Relative luciferase activity (% of LPS treated) G -CSF in medium (ng·mL 1) A Y.-Y Chou et al E * * 12 Time (h) 10 0 80 60 40 20 24 LPS Rapa 0.2 1. 0 0.5 1. 0 1. 4 1. 7...
Ngày tải lên: 22/03/2014, 17:20
Báo cáo khoa học: "Granulocyte-colony stimulating factor producing rectal cancer" docx
... producing granulocyte -colony stimulating factor: a case report Cancer 19 98, 82: 210 2- 211 1 Ikeda T, Ohgaki K, Miura M, Aishima S, Shimizu T, Maehara Y: Granulocyte -colony stimulating factor- producing ... for G -CSF may become part of the treatment paradigm Abbreviations CRC: colorectal cancer; G -CSF: granulocyte -colony- stimulating factor; GM -CSF: granulocyte -macrophage colony stimulating factor; ... 10 11 12 13 14 15 Competing interests The authors declare that they have no competing interests Hasegawa S, Suda T, Negi K, Hattori Y: Lung large cell carcinoma producing granulocyte -colony- stimulating...
Ngày tải lên: 09/08/2014, 07:21
Báo cáo y học: "Effect of a structurally modified human granulocyte colony stimulating factor, G-CSFa, on leukopenia in mice and monkeys" docx
... ± 13 98 9858 ± 2333a 14 650 ± 2861b 11 092 ± 2 319 a 10 592 ± 15 47 a G-CSFa (25 mg/kg) 11 083 ± 2724 855 ± 342 2508 ± 923 19 00 ± 972 5483 ± 973 819 2 ± 27 21 111 92 ± 4593 12 917 ± 2921b 10 533 ± 17 41 G-CSFa ... mg/kg) 10 178 ± 4 014 11 00 ± 412 2042 ± 687 2508 ± 565 5325 ± 11 39 9250 ± 3766a 10 975 ± 3052a 13 950 ± 3087b 13 075 ± 312 0a G-CSFa (10 0 mg/kg) 11 814 ± 3802 11 75 ± 344 2783 ± 12 33 4483 ± 13 94 6325 ± 17 26 ... d9 d12 d16 d19 d23 d26 d34 Control 11 413 ± 2089 12 33 ± 553 2450 ± 11 04 2533 ± 850 3342 ± 811 5083 ± 260 7925 ± 16 67 7575 ± 18 58 8750 ± 2203 Wt G -CSF (50 mg/kg) 10 996 ± 27 31 1342 ± 337 310 0 ± 14 08...
Ngày tải lên: 10/08/2014, 21:23
Báo cáo y học: " Aggressive cutaneous vasculitis in a patient with chronic lymphatic leukemia following granulocyte colony stimulating factor injection: a case report" pot
... monocytic leukaemia Med Clin 19 97, 10 9:238-239 Conclusion In conclusion, patients should be monitored for development of inflammatory processes during G -CSF doi :10 .11 86 /17 52 -19 47-5-88 Cite this article ... in this context with granulocytic colony- stimulating factor (G -CSF) treatment Cutaneous vasculitis was reported in less than one in 7000 of those treated with G -CSF, and was moderate to severe ... with chronic lymphatic leukemia following granulocyte colony stimulating factor injection: a case report Journal of Medical Case Reports 2 011 5:88 Competing interests The authors declare that they...
Ngày tải lên: 11/08/2014, 00:22
Báo cáo y học: "Association of the T allele of an intronic single nucleotide polymorphism in the colony stimulating factor 1 receptor with Crohn''''s disease: a case-control study" ppt
... (57%) 32 ( 91% ) (87%) (10 0%) 12 (10 0%) 94 (16 %) (43%) (9%) (13 %) (0%) (0%) 14 43 35 12 10 8 Acadian Non-Acadian Total 10 (53%) (47%) 19 71 (77%) 21 (23%) 92 81 30 11 1 Table 3: Ethnicity vs CSF1 R A2003T ... Table 1: Crohn's Disease Status vs CSF1 R A2033T SNP: All Patients CDT Allele Absent T Allele Present Total CD+ Total 94 (87%) 14 (13 %) 10 8 81 (73%) 30 (27%) 11 1 17 5 44 219 χ2 = 6.74 (p < 0. 01) O.R.:2.49 ... African-American Caucasian Hispanic Jewish Unknown Total 10 (53%) 17 (85%) 44 (75%) (10 0%) (80%) (67%) 81 (47%) (15 %) 15 (25%) (0%) (20%) (23%) 30 19 20 59 11 1 CONTROL PATIENTS T Allele Absent T Allele Present...
Ngày tải lên: 11/08/2014, 10:23
Báo cáo y học: " Anaplastic carcinoma of the pancreas producing granulocyte-colony stimulating factor: a case report" potx
... Interstitial pneumonia in patients receiving granulocyte colony- stimulating factor during chemotherapy: survey in Japan 19 91 96 Br J Cancer 19 97, 76 (12 ) :16 61- 1666 Publish with Bio Med Central and every scientist ... granulocyte colony- stimulating factor Am J Gastroenterol 20 01, 96 (1) :258-259 Page of (page number not for citation purposes) Journal of Medical Case Reports 2008, 2:3 91 10 11 12 13 http://www.jmedicalcasereports.com/content/2 /1/ 3 91 ... Rinsho 19 89, 35(4):523-527 Uematsu T, Tsuchie K, Ukai K, Kimoto E, Funakawa T, Mizuno R: Granulocyte -colony stimulating factor produced by pancreatic carcinoma Int J Pancreatol 19 96, 19 (2) :13 5 -13 9...
Ngày tải lên: 11/08/2014, 19:21
Báo cáo khoa học: "Monocyte deactivation in neutropenic acute respiratory distress syndrome patients treated with granulocyte colony-stimulating factor" ppt
... (n = 10 ) Non-neutropenic patients (n = 12 ) Neutropenic patients (n = 10 ) TNFα 25 (10 –50) 10 0 (10 –400)*† 10 (10 10 ) IL -1 20 (15 –45) 30 (15 –870) 15 (15 15 ) Spontaneous production IL-6 85 (10 11 5) ... 10 (10 10 ) IL -1 855 (10 5 1, 550)*‡ 7,900 ( 410 –9 ,12 0)*†‡ 15 (15 15 ) IL-6 IL -1 receptor antagonist IL -10 6205 (520–8,825)*‡ 10 45 (340–2,250)*‡ 305 (70–805)*‡ 53,720 (13 ,800–79,450)*†‡ 720 (3 1, 113 ) ... http://ccforum.com/content /12 /1/ R17 adult respiratory distress syndrome Acta Haematol 19 99, 10 1 :12 4 -12 9 21 Hotchkiss RS, Karl IE: The pathophysiology and treatment of sepsis N Engl J Med 2003, 348 :13 8 -15 0 Page...
Ngày tải lên: 13/08/2014, 10:20
Khảo sát lên men, thu nhận, tinh chế và dung hợp Granulocyte Colony Stimulati factor (G-CSF) tái tổ hợp từ E. coli với Polyethylenglycol (PEG)
... colony stimulating factor g -csf Gen mã hoá cho protein hG -CSF G-CSFR Thụ thể protein hG -CSF (hG -CSF receptor) G-MCSF Granulocyte macrophage colony stimulating factor IBs Inclusion Bodies IL -1 ... 11 2.2 Chữa bệnh Neutropenia G -CSF 12 2.3 Một số sản phẩm G -CSF thương mại 14 SỰ BIỂU HIỆN PROTEIN G -CSF Ở ESCHERICHIA.COLI 16 3 .1 G -CSF dạng thể vùi điển hình 16 ... GRANULOCYTE COLONY STIMULATING FACTOR (G -CSF) 1. 1 Giới thiệu chung 1. 2 Cấu trúc hình thái 1. 3 Nguồn gốc chế hoạt động 1. 3 .1 Nguồn gốc 1. 3.2 Cơ...
Ngày tải lên: 04/02/2015, 12:46
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