gods whose names are not associated with infamy have been better dealt with than the select gods whose infamies are celebrated
Báo cáo khoa hoc:" Functional polymorphisms in the promoter regions of MMP2 and MMP3 are not associated with melanoma progression" potx
... interests The author(s) declare that they have no competing interests Authors' contributions JC carried out the genotyping, participated in the selection of SNPs, analysis, and prepared the manuscript; ... when individuals with the C-1306-C-735 haplotype were compared to subjects with the T-1306-T-735 haplotype (OR = 6.53; 95% CI = 2.78–15.33) [11] The MMP3 5A allele was associated with a poorer prognosis ... wild type C allele at position -735 The analysis with the UCSC Genome Browser did not show any conserved sequence within the region bearing the new variant [12] The allele frequencies for MMP2 -1306...
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Báo cáo y học: "Levels of anti-citrullinated protein antibodies and IgM rheumatoid factor are not associated with outcome in early arthritis patients: a cohort study" ppt
... response to therapy and thus be related to outcome Therefore, we investigated whether baseline status or levels of ACPA or IgM-RF and their changes in the year thereafter are associated with disease ... in levels in the first year were not correlated with the two-year outcome measures (all P > 0.10) ACPA or IgM-RF-negative patients were not further analysed since their levels did not change significantly ... of the baseline levels Higher baseline levels were correlated with a larger absolute change in the first year (r = -0.44, P < 0.001), but barely with the relative change (r = -0.09, P = 0.04) The...
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Báo cáo khoa học: "bcl-2 expression is not associated with survival in metastatic cutaneous melanoma: A historical cohort study" pptx
... and third, the interaction between the other members of the BCL-2 family may have neutralized the expression of bcl2 The regulation of proapoptotic and antiapoptotic components in the BCL-2 family ... melanomas, others have observed the opposite [11-15] Grover et al [11] have reported a lower survival rate in CM patients with regional lymph node metastasis and positive bcl-2 expression The purpose ... was present in the same site, only the first metastasis at each site was evaluated for bcl2 protein expression Thirty patients did not receive any treatments other than surgery Of the remaining...
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Báo cáo y học: "The MHC2TA -168AG gene polymorphism is not associated with rheumatoid arthritis in Austrian patients" pps
... was not significantly associated with rheumatoid factor positivity, with an aCCP antibody titer stage of RA, or with the age at onset of the disease (Table 2) In the present study, MHC2TA genotype ... Interestingly, the GG genotype frequency was significantly higher in the Austrian controls compared with the Swedish controls: 10.5% of the Austrian matched controls but only 4.8% of the Swedish ... We are aware that this low power is a major limitation of the present study Further larger studies are necessary to draw firm conclusions on the role of the MHC2TA polymorphism for RA We did not...
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Báo cáo y học: "Deficiency of functional mannose-binding lectin is not associated with infections in patients with systemic lupus erythematosu" pptx
... study [10] Another explanation for the discrepancy between the genotypic and the phenotypic data could be that unidentified linkages between mutations or polymorphisms in the MBL gene with mutations ... was not significantly associated with the occurrence of the first major infection in the best multiple logistic regression model Moreover, the median serum creatinine level at the moment of the ... in the design of the study and reviewed the draft of the manuscript MRD participated in the design of the study, supervised the performance of the MBL pathway activity ELISA, and reviewed the...
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Báo cáo y học: "The interferon induced with helicase domain 1 A946T polymorphism is not associated with rheumatoid arthritis" pptx
... were not normally distributed and the differences were therefore compared using the Mann–Whitney nonparametric tests The interquartile range represents the 25th and 75th percentiles of the distribution ... RA cases (0.21 ± 0.5) than in healthy controls (0.10 ± 0.2) (P < 0.0001) (Figure 1) We further investigated whether the IFIH1 A946T genotype was associated with mRNA levels The IFIH1 mRNA levels ... performing logistic regression The model with the largest log-likelihood ratio was chosen as the one that best represented the mode of inheritance of the data Page of (page number not for citation purposes)...
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Báo cáo y học: "Leg-length inequality is not associated with greater trochanteric pain syndrome" pps
... Although these purported associations are theoretically plausible, they have not been evaluated We could find only one report of an association between GTPS and LLI listed on MEDLINE The report ... interests The authors declare that they have no competing interests Authors' contributions NAS developed the study hypotheses and analysis plan, participated in the statistical analysis, and drafted the ... not to have GTPS, as the absence of pain in the region or radiating distally from this area would preclude the presence of a pain syndrome Since we wished to study trochanteric area pain, not referred...
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Báo cáo y học: "Use of methotrexate therapy is not associated with decreased prevalence of metabolic syndrome" potx
... Arthritis Research & Therapy Vol 11 No Raterman et al Table Characteristics of the study population MetS presenta n = 84 MetS absenta n = 265 MetS ... RA, rheumatoid arthritis; SSZ, sulfasalazine; TNF, tumour necrosis factor Table Variables associated with metabolic syndrome Multivariatea Univariate OR Body mass index 95% CI P value OR 95% ... National Cholesterol Education Program (NCEP) 2001; bMetS according to NCEP 2004 Continuous variables are presented as means (± standard deviations) in cases of normal distribution or as medians (interquartile...
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Báo cáo y học: "Use of methotrexate therapy is not associated with decreased prevalence of metabolic syndrome – authors’ respons" pps
... Arthritis Research & Therapy Vol 11 No Toms et al Competing interests The authors declare that they have no competing interests Acknowledgements This work is ... scholarship from the Empirikion Institute, Athens, Greece References Toms TE, Panoulas VF, Douglas KMJ, Kitas GD: Methotrexate therapy associates with a reduced prevalence of the metabolic syndrome ... glucocorticoid use and presence of the metabolic syndrome in patients with rheumatoid arthritis: a cross-sectional study Arthritis Res Ther 2008, 10:R145 Page of (page number not for citation purposes)...
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Báo cáo khoa hoc:" The checkpointkinase 2 (CHK2) 1100delC germ line mutation is not associated with the development of squamous cell carcinoma of the head and neck (SCCHN)" potx
... patients, they did not detect any truncating mutation Therefore, we were able to confirm these results Nevertheless, they found the missense I157T mutation in 4.1% of the cases In this study, the incidence ... showed the presence of the 1100delC variant Discussion None of the investigated 91 patients with SCCHN carried the CHK2 1100delC variant The incidence of 1100delC in the population of the state ... for the development of SCCHN, at least some of the patients should have been positive for this mutation The heterozygous germ line mutation 1100delC of CHK2 was previously reported to be associated...
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Báo cáo khoa hoc:" The CTGF -945GC polymorphism is not associated with plasma CTGF and does not predict nephropathy or outcome in type 1 diabetes" pptx
... DN Apparently, the association of the CTGF -945GC SNP with disease is not the same in all patient groups and categories, as has been noted in previous studies that could not always confirm the ... levels with genotype has not been assessed This hampers an adequate interpretation of the effect of the polymorphism on in vivo CTGF transcription and translation Therefore, we compared genotype ... carried out the genotyping assays, analyzed the data and wrote the manuscript TQN participated in the design of the study and helped revise the manuscript LB helped set up the genotyping assay...
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Báo cáo khoa hoc:" Variation in the CXCR1 gene (IL8RA) is not associated with susceptibility to chronic periodontitis" ppt
... in the IL8 and in the CXCR2 genes with CP [26,27] Because those previous findings and the biological relationship of the CXCR-1 with the IL-8 and the CXCR-2 [1,5] we have hypothesized whether ... 1) The minor allele frequency (MAF) was 0.087, and the genotype distribution of the rs2234671 SNP in the CXCR1 gene was consistent with the assumption of the Hardy-Weinberg equilibrium for the ... admixtured, the skin color is not related with ancestry according to Pena et al [41], Parra et al [42] and Pimenta et al [43] In regards to our hypothesis whether the rs2234671 SNP in the CXCR1...
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Báo cáo khoa hoc:" Sporadic ALS is not associated with VAPB gene mutations in Southern Italy" ppt
... ALS4, a rare juvenile-onset disorder, associated with mutations of the senataxin gene (SETX) [3] An autosomal recessive, juvenile-onset form (ALS2), has been associated with mutations of the Alsin ... forms of the disease The most common form of FALS is autosomal dominant for which to date genes have been identified: ALS1, with adult-onset caused by mutations in the gene encoding the cytosolic ... motor neurons of the spinal cord and brain More than 90% of ALS patients are sporadic (SALS), not showing any familial trait Approximately 10% of cases are familial (FALS), and within these lie several...
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Báo cáo y học: "TRAF1/C5 polymorphism is not associated with increased mortality in rheumatoid arthritis: two large longitudinal studies" pot
... there was no selection of the protective genotype in the RA or non-RA cohort This makes an early death in the risk genotype carriers unlikely and further supports the lack of association of these ... in the disease course are not part of their cohort This hypothesis was corroborated by our results in the RA cohort, which showed that most of the CVD-related deaths were concentrated in the ... Twenty-five percent of these patients carried the GG genotype, 57% the AG genotype and 18% the AA genotype The survival probability of rs10818488 genotypes and all-cause mortality is presented...
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Bóa cáo y học: " Helicobacter pylori infection is not associated with an increased hemorrhagic risk in patients in the intensive care unit" potx
... lower than in previous serological studies [5,14,19] and might corroborate the low rate found with the swab sampling The exclusion from the study of the patients with a history of ulcers might have ... patients with clinical evidence of bleeding (excluding those with extra-digestive bleeding) were compared with those of the patients without bleeding (Table 3) Survival was significantly better ... patients without bleeding than in patients with clinical evidence of bleeding during their ICU stay (p < 0.001) Using multivariate analysis, the bleeding risk was independently associated with SAPS...
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Báo cáo y học: " Off hour admission to an intensivist-led ICU is not associated with increased mortality" pps
... quality of care round the clock In the present study, the definition of off hour was based on the presence or absence of the intensivist in the ICU Future studies should investigate whether the organisational ... The idea for the study was conceived by all authors together at a reunion party IAM analyzed the data from the RDGG and the aggregate data, wrote the first version of the manuscript and together ... Hospital mortality associated with day and time of admission to intensive care units Intensive Care Med 2004, 30:895-901 Competing interests The authors declare that they have no competing interests...
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Báo cáo y học: " Insulin-treated diabetes is not associated with increased mortality in critically ill patients" ppt
... associated with increased mortality in patients with community-acquired bacteremia in another study [24] In patients with acute myocardial infarction, diabetes has been associated with increased ... that diabetes was associated with increased infectious complications but not with increased mortality [27] Similar findings have been reported in burn patients [9] and in patients with acute heart ... patients with a history of diabetes had similar 28-day and 90-day mortality rates to the other patients [30] In the present study, the incidence of infections acquired during the ICU stay was not...
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Báo cáo y học: "Resuscitation with low volume hydroxyethylstarch 130 kDa/0.4 is not associated with acute kidney injur" pot
... the three-week follow up (P < 0.0001) and then the difference disappeared (P = 0.23) The RIFLE classification (Figure 2) had the same kinetic: initially higher in the HES group (P = 0.007), with ... comparing HES with other fluid therapies and found a 1.5 fold risk of developing AKI with HES, with an increased risk in septic patients [32] However, the results are limited by the different ... survey Our results not support that HES are not nephrotoxic, but suggest that in our daily practice, their use is not directly associated with AKI However, our results must be taken with caution because...
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Báo cáo sinh học: "Second chromosome polymorphism of Drosophila buzzatii in a natural population is not associated with gametic selection and does not affect mating pattern" potx
... have been applied to the study of natural selection in nature (see Endler, 1986 for a review) One of them consists of dividing total selection into partial components throughout the life-cycle (selection ... only the adaptive significance of the second chromosomal polymorphisms, but also that certain chromosomal arrangements are favoured during one selective episode and selected against in another, ... to the collecting baits and random mating can be accepted, and even the apparent weak gametic selection against 2st would not affect our previous results ACKNOWLEDGMENTS The authors wish to thank...
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Báo cáo khoa học: "Phospho-ERK and AKT status, but not KRAS mutation status, are associated with outcomes in rectal cancer treated with chemoradiotherapy" ppt
... patients with the wild-type (WT) KRAS gene These drugs are now used in the treatment of mCRC, with response rates ranging from 8% with single agent cetuximab[36] to 23% in combination with irinotecan, ... treatment with chemoradiotherapy was selected At the time of surgery, 43% of patients were downstaged and 17% had a pCR All but two patients received concurrent 5-FU chemotherapy with the radiation There ... activation are associated with better response to chemoradiotherapy Based on existing preclinical information, we hypothesized that activation of either AKT or ERK would antagonize chemoradiotherapy...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các mục tiêu của chương trình xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản khảo sát chương trình đào tạo gắn với các giáo trình cụ thể xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008