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Tài liệu Male Reproductive Health Disorders and the Potential Role of Exposure to Environmental Chemicals pdf
... 2007 Dysgenesis and histological changes of genitals and perturbations of gene expression in male rats after in utero exposure to antiandrogen mixtures Toxicol Sci 98: 87-98 Mocarelli P, Gerthoux ... androgen production, for example) which is then linked to an outcome disorder(s) There are huge practical and ethical obstacles to being able to this definitively, and this has to be taken into ... the number of Sertoli cells in his testes: these control the process of spermatogenesis and each Sertoli cell can only support a fixed number of germ cells through development into sperm (Sharpe...
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Tài liệu Báo cáo khoa học: "Dialogue and Understanding Development Environment, mapping Business Process Models to Information State Update dialogue systeDialogue and Understanding Development Environment, mapping Business Process Modelsms" pptx
... created the agent247(TM) Dialogue Modelling component with dynamic prompt and Grammar generation for Natural Language Understanding BPM agent (java) and Database agent (java) ¢ Automation of contact ... Customers are now able to immediately declare their goals (“I want to change my address”) rather than having to laboriously navigate a series of multiple-choice ... show how to elaborate business process models with linguistic information of various types (e.g how to generate appropriate clarification questions), and we show an ISU dialogue management component,...
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Báo cáo khoa học: "Applying Morphology Generation Models to Machine Translation" docx
... according to inverted and direct channel models estimated by relative frequency, lexical weighting channel models following Vogel et al (2003), a trigram target language model, two order models, ... log-probabilities according to inverted and direct channel models estimated by relative frequency, lexical weighting channel models, a trigram target language model, distortion, word count and phrase ... base MT system is trained to produce sequences of stems in the target language The most straightforward way to achieve this is to stem the training parallel data and to train the MT system using...
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Social Perspectives in Mental Health Developing Social Models to Understand and Work with Mental Distress potx
... ultimately seek to comprehend (Beresford, 2003) If we are to home in on, and start to make sense of, what is really important to people, we must value and engage with the ‘standpoint’ knowledges of those ... allegiance: to the empowerment of service users and social change in line with their rights and needs Its rationale is to bring about change, rather than solely to act as an instrument for knowledge production ... relation to mental health service user/survivor knowledge generally and with regard to survivor involvement in research (Faulkner, 2003) Thus service users’ knowledge and analysis is beginning to impact...
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Báo cáo khoa học: Recent contributions of in vitro models to our understanding of hepatitis C virus life cycle pdf
... shown to be infectious and able to replicate efficiently in the newly described HPV18 ⁄ E6E7-immortalized hepatocytes In this experiment, interferon regulatory factor-7, a regulatory factor of ... hepatitis C virus genotype 1a RNAs in cell culture J Virol 77, 3181– 3190 17 Kato T, Date T, Miyamoto M, Furusaka A, Tokushige K, Mizokami M & Wakita T (2003) Efficient replication of the genotype 2a ... Takada Y, Egawa H, Uemoto S & Shimotohno K (2007) Serum-derived hepatitis C virus infectivity in interferon regulatory factor-7-suppressed human primary hepatocytes J Hepatol 46, 26–36 45 Lerat...
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Solving Enterprise Applications Performance Puzzles: Queuing Models to the Rescue doc
... “Garbage in, Garbage out” Models, 68 Realistic Workload, 69 Users’ Redistribution, 72 Changing Number of Users, 72 Transaction Rate Variation, 75 Take Away from “Garbage in, Garbage out” Models, ... hand, if the system appears to the users to be slow and getting even slower and slower as more users log in, then the performance analyst has to use the tools of his trade to fix the issues Application ... by queuing models: Bridge toll Cars are requests; booths are servers Grocery store Visitors are requests; counters are servers Cellular phone network Phone calls are requests; phone towers are...
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Báo cáo khoa học: "Sparse Information Extraction: Unsupervised Language Models to the Rescue" pptx
... addition to locating the proper nouns in the corpus, L EX also concatenates each multi-token proper noun (e.g.,Los Angeles) together into a single token Both of R EALM’s components construct language ... leverage IR research to compare them, as described below To assess each extraction, we determine how similar its context vector is to a canonical seed vector (created by summing the context vectors ... languagemodeling system called R EALM that combines both HMM-based models and relational ngram models, and shows that R EALM reduces error by an average of 39% over previous methods, when applied to...
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Báo cáo khoa học: "Adapting Translation Models to Translationese Improves SMT" pot
... tables an additional factor, as a measure of its fitness to the genre of translationese We experiment with two such factors First, we use the language models described in Section to compute the cross-entropy ... French -to- English, but it drops to 0.46 for the reverse task The covering set average length measure shows similar behavior: R2 drops from 0.75 in French -to- English to 0.56 in Englishto-French ... (FO) to refer to the subsets of the corpus that are translated from English to French and from French to English, respectively The translation tasks are English-toFrench (E2F) and French -to- English...
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báo cáo hóa học: " Using animal models to determine the significance of complement activation in Alzheimer''''s disease" pptx
... months of age, and increases with age; total Aβ burden peaks at one year of age, although the percentage of Aβ that is fibrillar (thioflavin-S reactive) increases up to years of age Matsuoka ... 629:245-252 McGeer PL, Rogers J: Anti-inflammatory agents as a therapeutic approach to Alzheimer's disease Neurology 1992, 42:447-449 Rogers J, Kirby LC, Hempelman SR, Berry DL, McGeer PL, Kaszniak ... bacterium long identified as a respiratory pathogen It has more recently been demonstrated to be a causative agent in reactive arthritis [122] and to be associated with autoimmune disorders including...
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báo cáo hóa học:" Extending basic principles of measurement models to the design and validation of Patient Reported Outcomes" docx
... inadequate coverage of important alternatives to classical factorial models; such as the use of linear combinations of independent items, single item indicators, or other scalar metrics, seems to imply ... Indicator models Starting with the top left quadrant of Figure with Model A, the Multiple Effect Indicator (MEI) model represents what most people commonly refer to as the latent construct or factorial ... Multiple Mixed Indicator models One final family of measurement models is what Bollen and Lennox [21] refer to as the Multiple Mixed Indicator (MMI) model As the name implies, such models contains...
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Báo cáo sinh học: " Research Article Employing Second-Order Circular Suprasegmental Hidden Markov Models to Enhance Speaker Identification Performance in Shouted Talking Environments" potx
... First-Order Left -to- Right Suprasegmental Hidden Markov Models First-Order Left -to- Right Suprasegmental Hidden Markov Models have been derived from acoustic FirstOrder Left -to- Right Hidden Markov Models ... CSPHMM2s are superior models to each of First-Order Left -to- Right Suprasegmental Hidden Markov Models (LTRSPHMM1s), SecondOrder Left -to- Right Suprasegmental Hidden Markov Models (LTRSPHMM2s), ... first-order left -to- right, second-order leftto-right, first-order circular, and second-order circular models were trained on top of acoustic: first-order left -to- right, second-order left -to- right, first-order...
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Requirements Engineering From System Goals to UML Models to Software Specifications docx
... requirement: prescriptive statement refering to requirement environment phenomena (not necessarily shared) – to be enforced by the software -to- be possibly together with other system components – formulated ... configuration evolution management in SE – System modeling: conceptual models in DB & MIS; task modeling models in HCI; knowledge representation in AI www.wileyeurope com/college/van lamsweerde Chap.1: ... MotorRaising World phenomena Shared phenomena DriverWantsToStart Machine phenomena motor.Regime = ‘up’ stateDatabase updated errorCode = 013 HandbrakeReleased World www.wileyeurope com/college/van...
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Báo cáo sinh học: "Models to estimate maternal effects for juvenile body weight in broiler chickens" pptx
... (1990) Owing to their hemizygous form these genes are likely to be driven towards fixation, especially in meat-type poultry with a long and extensive selection history for growth traits The genetic ... suggested sensitivity of maternal effects to different fixed effects models In our data different parental flocks of different ages and farms contributed offspring to one hatch week The age difference ... estimates dropped somewhat For the models 12a and 12c the m estimate increased by a factor of 1.5 to (from 0.04 (0.04) to 0.07 (0.06) in population A and from 0.03 (0.02) to 0.05 (0.04) in population...
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Báo cáo y học: "The role of the Notch pathway in healthy and osteoarthritic articular cartilage: from experimental models to ex vivo studies" pdf
... Notch/Jagged signaling maintains the progenitor cell state [47,48] Taken together, the results of these studies suggest that Notch/Jagged signaling promotes the maintenance of the progenitor phenotype ... immunohistochemical localization of Notch receptors and ligands in human articular cartilage, chondroprogenitor culture and ultrustructural characterestics of these progenitor cells Acta Histochem ... activates transcription of its target genes [7,18-21] (Figure 2) To date, two major Notch primary target genes have been identified, HES and HERP These Notch effectors belong to the basic helix-loop-helix...
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Báo cáo sinh học: "The use of fixed effect models and mixed models to estimate single gene associated effects on polygenic traits" pot
... individuals should be generated In most cases, this will require pedigree records for several generations of ancestors prior to the first investigated generation In addition to the genetic relationship ... be designed to ensure genetic ties across genotypes for the investigated gene Model is less sensitive to this type of problems but a certain degree of genetic relationship across genotypes for ... realized additive S 3m genetic effect of each ancestor genotype to obtain the estimates, while Model Applying according to - average heritability for the entire material Since MHC genotypes were distributed...
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MURINE MODELS TO STUDY IMMUNITY AND IMMUNISATION AGAINST RESPIRATORY VIRAL PATHOGENS
... histograms of MHC-Peptide binding assay 2.9 51 2.10 51 2.11 51 2.12 Cytotoxicity of PBS control immunized mice 2.13 Cytotoxicity of splenocytes from mice immunized with DNA vector 2.14 Cytotoxicity ... cellular responses by genetic regulatory networks, transcription factors are able to control the expression of a diverse set of target genes to orchestrate and control homeostatic mechanism of ... influenza virus infection Cr Cytotoxicity assay of OTI splenocytes in vitro stimulated with ConA against various target cells Cr Cytotoxicity assay of purified-CD8+ cytotoxic T cells from C57BL/6...
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A methodology for validation of integrated systems models with an application to coastal-zone management in south-west sulawesi
... as: to what extent can such models contribute to our knowledge and ability to manage our environment? Are they useful and they have an added value in comparison with conventional process models? ... the importance of using models as tools to assist the policy analysis These models can be referred to as policy analysis models (Miser and Quade, 1985) or rapid assessment models (De Kok and Wind, ... participatory management and adaptive management (Miser and Quade, 1988; Clark, 2002; Bennett et al., 2004) These concepts were derived to take into account the multiple perspectives of different agents...
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