endocannabinoids and kisspeptins two modulators in fight for the regulation of gnrh activity
Báo cáo y học: " Combined forced oscillation and forced expiration measurements in mice for the assessment of airway hyperresponsiveness" pot
... manoeuvre performed with a reservoir pressure of -35 cmH2O and a PEEP of cmH2O Then, we administered a DI and obtained another set of FOT data Similar data were obtained in our main experiments in OVA-sensitized, ... specifically the constant-phase model [13], can provide valuable information pertaining to the heterogeneity of the respiratory response and whether it is dominated by resistance of the conducting airways, ... pressure of 30 cmH2O held for seconds) before the plethysmograph was sealed for the rest of the experiment The animal was ventilated at a respiratory rate of 150 breaths/min and tidal volume of 10...
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INTERNATIONAL STANDARD Microbiology of food and animal feeding stuffs — Horizontal method for the detection of Salmonella spp docx
... information concerning the strain(s) and whether it is an outbreak or in food 10 Expression of results In accordance with the results of the interpretation, indicate the presence or absence of ... licensed to and installed on the computer performing the editing In downloading this file, parties accept therein the responsibility of not infringing Adobe's licensing policy The ISO Central Secretariat ... this culture for examination for the H-antigens, proceeding according to 9.5.4.2, but using one drop of the anti-H serum (5.3) instead of the saline solution If agglutination occurs, the reaction...
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Báo cáo Y học: Identification of mammalian-type transglutaminase in Physarum polycephalum Evidence from the cDNA sequence and involvement of GTP in the regulation of transamidating activity potx
... per site terminus that is required for binding to the plasma membrane, thereby being involved in the formation of the corneum [47] Additional amino-terminal residues of TGase include the sequences ... form Initially, determination of the amino-terminal amino acid sequence of purified protein was attempted, but no information was obtained, probably due to the protein modification Therefore, the ... suggesting that the purified PpTGase is responsible for the major cross-linking reaction in P polycephalum Furthermore, the result of the Northern blotting indicates that a single species of transcript...
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Báo cáo khoa học: The structural comparison of the bacterial PepX and human DPP-IV reveals sites for the design of inhibitors of PepX activity pot
... residues involved in positioning the substrate in the active site (labelled Pos1 to Pos4); residues involved in the stabilization of the substrate in the active site (Stb1 and Stb2); those forming the ... lactis The results are presented in Table and Fig 4A For the cluster of lowest energy, both the position and the conformation of the ligand are close to those observed in the 3D structure of the ... group of the ligand and the NH2 of Asn470 (equivalent to Asn710 in DPP-IV) Another potential bond can be proposed between the OH atom of Tyr380 and the carbonyl group of the ligand Finally, the...
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Báo cáo khoa học: cGMP and glutathione-conjugate transport in human erythrocytes The roles of the multidrug resistance-associated proteins, MRP1, MRP4 and MRP5 pot
... producing 50% inhibition of the inhibitable component, U0 is the uptake in the absence of the inhibitor, Unoninh is the uptake which cannot be inhibited and ni is the Hill coefficient for the inhibitor ... and that vincristine inhibits the high affinity DNP-SG transport in the presence but not in the absence of GSH [12,45,46] Thus the effect of vincristine on the cGMP uptake was also tested in the ... by AF and all data in the second by CF For fits of the two component Hill equation, there are 22 remaining degrees of freedom The one and two component fits are compared with each other using an...
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Báo cáo khoa học: " Comparison of two sap flow methods for the estimation of tree transpiration" ppt
... consisted of two cylindrical probes of mm in diameter, which were inserted 0.02 m into the sapwood of the bole, one above the other (0.2 m) The upper probe contained a constantan heating element ... amount of transpiration in the morning This study confirmed the possibility of experiment one or the other method in accordance with the objectives, and the equipment The major problem is still the ... choice of samples required for an accurate estimation of transpiration The combination of the two methods seems possible in the same experiment The heat balance for the small trunks, and transpiration...
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Báo cáo y học: "γ A novel mechanism for the regulation of IFN-γ inducible protein-10 expression in rheumatoid arthritis" ppsx
... ligand, may be expressed in the inflamed synovium of RA, and appears to play an important role in the recruitment of Th1-type cells into the joint Thus, the aim of the present study was to examine ... FLSs, indicating that the major cellular sources of IP-10 are probably either monocytes or PMNs during coculture Involvement of integrin–ICAM-1 ligand interactions in the upregulation of IP-10 ... molecules, including the ICAM-1–integrin pathway [19,29] The potential role of these molecules in FLS–leukocyte interactions was investigated by assessing the capacity of specific antibodies to inhibit...
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Báo cáo y học: "Validation of a microwave radar system for the monitoring of locomotor activity in mic pptx
... Screening of the metronome and position of the apparatus and acquisition window • stretching; • scratching the fur with the front paws LED was connected to the radar and placed in the field of the ... evaluate the constancy in time of the recordings of each device, we considered the recordings as consisting of three 30- minute parts For the analysis of variance of the data, we considered the three ... determined the level of activity of each animal in terms of number of signals counted by the software The mice showed a significant difference in the length of the circadian period in LD and DD...
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báo cáo khoa học: "The grapevine guard cell-related VvMYB60 transcription factor is involved in the regulation of stomatal activity and is differentially expressed in response to ABA and osmotic stress" ppt
... MYB60 proteins and other closely related proteins from subgroup 1: a distinctive PHEEG signature in the MYB domain, located in the loop connecting the R2 and R3 repeats, and the lack of the first ... 2C) Interestingly, at this stage, the onset of ripening and the accumulation of sugars are correlated to increasing levels of ABA in the berry [30], suggesting a possible negative effect of the ... primordia in (A), showing staining at the base of trichomes (C) Detail of an emerging later root (D) 15-day-old pVvMYB60:GUS seedling (E) Magnification of leaf primordia in (D), showing staining of...
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IDENTIFICATION OF A MINIMAL CIS-ELEMENT AND COGNATE TRANS-FACTORS REQUIRED FOR THE REGULATION OF RAC2 GENE EXPRESSION DURING K562 CELL DIFFERENTIATION
... tens of thousands of base pairs away from the transcription start site Therefore dynamic interplay between the cis-acting elements and DNA binding proteins is needed for proper regulation of these ... kinase and helicase activity The kinase activity of this factor is required for the phosphorylation of the C-terminus domain (CTD) of Pol II that consists of repeats of the amino acid sequence ... catalytic center for substrate binding, and an N-terminal SWIRM domain, which is important for the stability of LSD1 The third domain is the tower domain that regulates the catalytic activity of LSD1...
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lien tran thi hong and holloway - 2014 - developments in corporate governance - the case of vietnam
... combined with lower payouts and lower values for the other The contradiction in the findings for the two groups of companies is somewhat perplexing as the findings for the companies with increased ... to the announcement on the announcement date and for the few days thereafter The findings again underline the paradoxical nature of dividends and although a better understanding of the impact of ... washing potatoes and other vegetables after realising that rural consumers, who grew potatoes in the Sichuan region in China, were using their washing machines for rinsing the mud off potatoes in...
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Study of the associated proteins of STAT3 and characterization of their functions roles of GRIM 19 and PIN1 in the regulation of STAT3 activity
... binding to the tyrosine kinase domain of JAK and therefore reducing the JAK kinase activity However, CIS has been reported to interfere with the phosphorylated tyrosine on the specific cytokine ... mediate the interaction with other proteins The DNA-binding domain resembles an eight-stranded β-barrel, where several loops between the β strands of this domain participate in DNA-binding Between the ... STUDY OF THE ASSOCIATED PROTEINS OF STAT3 AND CHARACTERIZATION OF THEIR FUNCTIONS: ROLES OF GRIM-19 AND PIN1 IN THE REGULATION OF STAT3 ACTIVITY LUFEI CHENGCHEN B Sc (Hons), NUS A THESIS SUBMITTED...
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Báo cáo hóa học: " ICP0 antagonizes Stat 1-dependent repression of herpes simplex virus: implications for the regulation of viral latency" potx
... were inoculated with × 105 pfu per eye of HSV-1 strain KOS-GFP or GFP relationship of the genotype and phenotype of these mice is defined in Table c The mean ± standard error of the mean of the ... HSV-1 infection of mice Female mice of the strains specified in Table were inoculated with HSV-1 at 6- to 10-weeks of age and were handled in accordance with the NIH Guide for the Care and Use of ... at the 5' end of each gene B The ICP0 genes of wild-type HSV-1 and the ICP0- viruses n212 and GFP The mutation in n212 introduces a 14 bp linker sequence into codon 212 of the ICP0 openreading...
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Báo cáo hóa học: " Research Article New Trace Bounds for the Product of Two Matrices and Their Applications in the Algebraic Riccati Equation" potx
... 3.1 In this section, we obtain the application in the algebraic Riccati equation of our results including 3.1 Some of our results and 3.1 cannot contain each other Theorem 3.1 If 1/p and K is the ... Journal of Inequalities and Applications Therefore, considering the application of the trace bounds, many scholars pay much attention to estimate the trace bounds for the product of two matrices ... Majorization and Its Applications, vol 143 of Mathematics in Science and Engineering, Academic Press, New York, NY, USA, 1979 17 C.-L Wang, “On development of inverses of the Cauchy and Holder inequalities,”...
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báo cáo khoa học: "Structure and expression of the maize (Zea mays L.) SUN-domain protein gene family: evidence for the existence of two divergent classes of SUN proteins in plants" pot
... ancient divergence of these two classes These data also suggest that the PM3 proteins originated early in the life of the plant kingdom, predating the origin of flowering plants The second, four ... summary of the five maize SUN-domain protein genes is provided in Table and the properties and motifs of the CCSD and PM3 subfamilies of these proteins are summarized in Table Conservation of Two ... proteins reside or function in the NE remains to be determined In addition to their difference in size and SUN domain locations, these protein subfamilies are distinct in other interesting ways...
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THESIS SUBMITTED FOR THE DEGREE OF DOCTOR OF PHILOSOPHY - CONSTRUCTIONS OF HIGHER ABILITY IN TWO MAINTAINED AND TWO INDEPENDENT SCHOOLS
... The political struggleof the last 35 yearsin the United Kingdom, concerning the purpose different forms of schooling and the conceptualisationof ability inherent in and role of polarised views (Giddens, ... imposition of ideas on schools individuals but instead is a problem posed which will find resolution of some kind in and the minds of individuals participating in it Or indeed, it may produce an ongoing ... within Maintained and Independent schools in relation to ability This was in order to illuminate differences and similarities within and acrossschools and to begin to understand the ways in which...
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Báo cáo y học: "Thioglycosides as inhibitors of hSGLT1 and hSGLT2: Potential therapeutic agents for the control of hyperglycemia in diabetes"
... metabolized in the intestine [27] Therefore, a chemical reaction to convert the substance in its active form, after intestinal absorption like in the case of O-glucosides, is not necessary In addition, ... at 460 and 580 nm After a 20 sec baseline reading, 0.1 ml of PBS containing 10 µM of the compound investigated was added, and the fluorescence signal was recorder for 40 sec The change in fluorescence ... phosphate-buffered saline (PBS; Invitrogen, Karlsruhe, Germany) and then incubated with 0.1 ml of a solution containing µM CC2-DMPE and 0.02% pluronic acid in PBS After in- cubation in the dark for 30 at...
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Genotoxicity of 255 chemicals in the Salmonella microsome test (Ames test) and 8-hydroxyguanine (8-OH-Gua) assay for the detection of carcinogens
... Identification of C8-modified deoxyinosine and N2- and C8-modified deoxyguanosine as major products of the in vivo reaction of N-hydroxy-6-aminochrysene with DNA and the formation of the adducts in isolated ... recommend the Ames test using these sensitive strains (especially YG1041 and/ or YG1042) in combination with the standard tester strains (TA98 and TA100 series), in order to detect the mutagenicity of ... mutagenic in the Ames test using YG1041, YG1042, YG3003 and/ or YG7108 strain, and 21 chemicals (8.2%) formed 8-OH-Gua in the rat hepatocytes oxidized DNA as shown in Fig These sensitive strains could...
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Sanitation in Urban Poor Settlement and the Importance of Education for the Reduction of the Diffused Pollution - A Case Study of Bauniabad, Bangladesh
... system In most of the cases, the wastewater at sampling point (inside of inlet chamber), point (inside of hydraulic chamber) and point (inside of soak pit), were found to be in solidified states In ... from the beginning of the installation and they understood the benefit of the option from the combination of hygiene education and their experience from the test plants CONCLUSIONS From the study, ... of the number of the people using latrine increased because of the growth of the people living in the same plots than testing period This means that there is a possibility to improve the performance...
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