... D- SA and BoNT ⁄ C and BoNT ⁄ D, there was limited identity between the C-terminal subdomains of the HCRs of BoNT ⁄ D- SA and BoNT ⁄ C (62%) This indicated that BoNT ⁄ D- SA and BoNT ⁄ C had undergone ... organized into two subdomains, an N-terminal jelly-roll domain and a C-terminal b-trefoil domain The rmsd values were ˚ ˚ 2.5 A for HCR ⁄ D- SA and HCR ⁄ Dand 0.5 A for HCR ⁄ D- SA and HCR ⁄ C ... contrast, does not have an extended b-hairpin loop Reproduced from [61] with permission Ganglioside binding by HCR ⁄ C and HCR ⁄ D- SA Early studies showed that HCR ⁄ C bound GD1b and GT1b [46]...
... nước muốn bảo v Ngoài ra, người muốn có học v Doctor nauk giáo viên hướng d n (Rukovodichel hay Supevisor), phải tự "mở lối" cho Có thể bảo v Doctor nauk luận án (kèm theo báo) sách viết Nói chung ... (Ph .D) năm cấp khoảng 23000 Ph .D Quy định có từ 2002 trước Uỷ ban Học v Học hàm kiêm cấp Ph .D Như kiểu Bộ GD&ĐT Việt nam cho phép trường cấp Cao học, giữ lại TS V lâu bỏ Pháp Nhưng mà học v ... TSKH Việt nam ) không muốn nhập học vv o làm Tốt Pháp bỏ Doctor Quốc gia (Xin lỗi tiếng Pháp để ghi nguyên bản) Nhưng mà Nga v n bảo thủ nên lâu Mỗi năm có khoảng 4000 Doctor nauk Uỷ ban học v ...
... further analysed The purified GLD1 showed activity with dl-glyceraldehyde and NADPH as a cofactor It had a very much reduced activity with DHA (Table 1) No activity was observed with NADH as a cofactor ... activity with C5 or C6 sugars We tested d- glyceraldehyde and l-glyceraldehyde individually and observed similar activities; the activity with l-glyceraldehyde was only slightly lower For d- glyceraldehyde ... specificities and kinetic properties of the histidine-tagged and purified GLD1 and GLD2 The reductive assay conditions were 10 mM sodium phosphate (pH 7.0) and 0.4 mM NADPH The oxidative assay conditions...
... England David Ricardo and, to a certain extent, both James Mill and his son John, in France Jean-Baptiste Say and Fr d ric Bastiat, and in Germany Henry and J H von Thünen, Rau, Hermann, and Nebenius ... is divided into fixed and circulating capital Fixed capital consists of land, buildings, machinery, tools, means of transport, and other permanent factors needed to produce the goods and services ... native land forever, Ballvé went first to France andv vi Foreword then to Mexico, where he acquired citizenship in 1943 and lived until his death in 1959 In Mexico City, in addition to the active...
... formula to the value process V yields o ˙ dV = Vx dX + V dt + Vxx d X ˙ = φ dX + V dt + Vxx d X Hence φ is self-financing if, and only if, V satisfies the differential equation ˙ V dt + Vxx d X = (15) ... According to Itˆ’s formula it follows o ˙ d = dV − Vx dX = V dt + Vxx σ X dt (16) But, whereas the return dXt (ω) depends on ω, the right-hand side of (16) does not, since Xt (ω) is fixed at ... and Local Martingales 41 Proof From Lemma 2.6.6 take Tn ↓ T andd ∈ Dn 1) For XTn ∈ FTn and B ∈ B d , t ≥ it follows {XTn ∈ B} ∩ {Tn ≤ t} = {XTn ∈ B} ∩ {Tn = d} t d Dn {Xd ∈ B} = t d Dn ∈Fd...
... creativity and design and their role in driving business performance and productivity It reviews the existing economic and management literature on creativity and design, and draws on five specifically ... weaknesses in creativity and design? G How can creativity and design enhance value and productivity in firms? G How can businesses develop and use creativity and design? G What role can Government play ... that have been put forward for these two concepts and shows how they are linked to innovation and research and development WHAT IS CREATIVITY? Creativity and design may be elusive and overlapping...
... showed very low CatE activity, and no CatD activity Moreover, the overall activity in the subcellular fractions of the three cell types tested varied substantially, as did CatE and CatD activity DCs ... with CatE-deficient and CatD-deficient mice have provided additional evidence of the association of these enzymes with different physiological effects CatD-deficient mice develop massive intestinal ... mixed with 0.5 lL DHB-matrix [10 mgÆmL)1 (w ⁄ v) 2,5-dihydroxybenzoic acid in 60% (v ⁄ v) ethanol containing 0.1% (v ⁄ v) Determination of cathepsin E andD activity trifluoroacetic acid] and applied...
... obtained during toxin radioiodination (see Experimental procedures) identified an iodinated Tyr22 in the first peak and an iodinated Tyr25 in the second peak Both iodinated derivatives did not differ ... determined by a BioRad Protein Assay Kit, using BSA as a standard Purification of d- ACTX-Hv1a and d- ACTX-Ar1 Radioiodination of d- ACTX-Hv1, LqhaIT and Lqh-II Crude venom was ÔmilkedÕ by direct aspiration ... A robustus spiders Crude venom was washed from pipettes with 0.1% (v/ v) trifluoroacetic acid and d- ACTX-Hv1a and d- ACTX-Ar1 isolated and purified by RP-HPLC Purification was achieved using a Pharmacia...
... already eat enough Undecided 1HELP evaluation instruments developed by Mary P Clarke, PhD, RD; Jacquelyn McClelland, PhD, RD; William D Hart, PhD, RD; and Alma Montano Saddam, PhD, RD of the Elderly ... elderly boyfriend; and one, with her teenaged grandson Two received both food stamps and home-delivered meals Three of the elders received homedelivered meals only—one, not because she needed ... impaired mobility (two in wheelchairs) and one had occasional dizzy spells Six lived alone; one with Family Economicsand Nutrition Review her daughter and husband, who died during the study; one,...
... collected and further identified by MALDI-TOF Peptide synthesis Arginine peptides l-, d- and l ⁄ d (6- and 9-mers), and their N-terminal acetylated derivatives were synthesized manually by standard ... removed under reduced pressure; and the residue was dissolved in water and washed with ethyl acetate (3 · 25 mL) The aqueous layer was evaporated under reduced pressure and the residue was dissolved ... concentrated and the residue was treated with ether to obtain a white solid, which was again made slurry in ether and decanted The solid material was dissolved in dichloromethane and treated with...
... paragraph, and (4) the rest Also, we divided texts in a TV newscasts into two: (1) title, and (2) the rest It is because keywords are distributed unevenly in articles of newspapers and TV newscasts, ... articles in T V newscast and newspapers: "Public work costs were a seven percent decrease" and "General annual expenditure dropped for three successive years" Sakai: A History and Evolution of Document ... kinds of T V news articles are fixed and quite different from those of the others From this, we concluded t h a t we had better align these kinds of T V news articles by the different method from...
... blessed I am, to have my dear mother and father, my aunt DaYi and grandmother, embrace me with fourtimes compounded love! Every fault, a tear, every wrong, a guiding hand and every triumph, an ... have rejoiced, laughed and shed tears of jubilation Such is the nature of Scientific Research, and indeed the grand Principia Vitæ These past half of a decade has been constituted of thousands ... sorrow and danced with me at the moments of delight And to you all my many dear beloved friends whose names, though I could not record here, I shall each and all engrave upon my heart And so composed...
... chapters and guided me to economic literature I might easily have overlooked Colette Ding and Liam Delaney acted as sounding boards and were always helpful and ready with suggestions To all the above ... will be produced per employee), (2) the productivity of these factors of production (better machinery, improved seeds and fertilisers and more advanced technology improve productivity), and (3) the ... initiatives in Asia, Latin America and, more tentatively, in Africa Most countries have abandoned the idea of development through intensive cultivation of the domestic market and have replaced it...
... Management and Practical Research and Dissertation is recommended It is good practice to use a variety of methods so that candidates’ interest and motivation are maintained and individual preferences ... Technology-Advanced Higher Advanced Higher Health and Food Technology Some suggested websites are provided below that cover Course content Food Standards Agency DEFRA www.food.gov.uk www.defra.gov.uk Current ... acquire a deeper knowledge and understanding of the factors which influence some of the choices and decisions made by individuals, families and societies apply skills of enquiry, analysis and evaluation...
... denatured to form single-stranded DNA The biotinylated amplicon is then captured on streptavidin-coated microwells and hybridized with HBV and internal standard-specific dinitrophenyl (DNP)-labeled ... B virus (HBV) DNA have been used widely (Table 1), but their interpretation and significance have yet to be defined HBV DNA assays are limited by lack of standardization and variable sensitivity ... phosphatase and visualized by alkaline phosphatase–based enzymatic reaction This procedure was initially developed by Drs Naoumov and Lau and was subsequently modified and extensively used in the...
... bind to receptors on target cells DHBV-infected ducks and woodchuck hepatitis virus (WHV)-infected woodchucks are the most widely accepted and frequently used animal models for the study of viral ... vortex-mix and sonicate the mixture to break up any gold clumps Add the required volume of plasmid (or plasmids) to achieve the desired DLR Mix DNA, spermidine, and gold by vortex-mixing for s While vortex-mixing, ... 4-mo-old ducks receiving the highest dose of virus were able to resolve their DHBV infection, and developed anti-DHBs antibodies Materials 2.1 Purification and Characterization of Duck Lymphocytes and...
... (Zakarpattia), Bukovyna, Odesa (Black Sea lands), and Crimea However, the broadest regional division of Ukraine commonly utilized in everyday life and in the media is the division into western and eastern ... warranted Culture and Customs of Europe features individual volumes on the countries most studied and for which fresh information is in demand from students and other readers The Series casts a wide ... Ukrainian lands have been coveted by their more powerful and aggressive neighbors Ukraine’s geography and size made it both more attractive to invaders and more difficult to defend Furthermore,...
... and PN, have been involved in drafting and critically revising the manuscript LI conceived and coordinated the study and draft the manuscript All authors read and approved the final version of ... (TRA) and beta subunits are comprised of a variable (V) and a constant (C) amino acidic region The TRBV region, referred according to the ImMunoGeneTics (IMGT) database [1], is encoded by V, diversity ... last clonotype (ID 1E2), identified by Cole et al [10], bore TRBV28 and TRBJ1-1 chains and differed only by the amino acid at position 109 (Figure 3) from ID 57, ID CTL01 and ID 6E4 clonotypes...