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Báo cáo Y học: Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules pptx
... particular, the four-stranded b sheet formed by the aminoacid residues at the N- and C-termini of PR contribute close to 75% of the total Gibbs energy [15] The importance of this four-stranded b ... mediated by the E138K mutation in the p51 subunit of HIV-1 RT [55] The introduction of this mutation into RT significantly diminishes the ability of TSAO to bind to and inhibit the enzyme [55] and ... is further emphasized by the fact that all PR dimerization inhibitors developed by ÔrationalÕ Short synthetic peptides corresponding to the amino-acid sequences of the N- and C-termini of HIV-1...
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IMPROVING THE TRANSPARENCY OF AUDITS: PROPOSED AMENDMENTS TO PCAOB AUDITING STANDARDS AND FORM 2 ppt
... of the other auditor, the country of headquarters' office location of the other auditor, and the magnitude of the portion of the financial statements audited by the other auditor Disclosing the ... disclose the name of the individual who performed the audit procedures and not the name of the entity The disclosure of the names of other participants in the audit would include the names of all ... requiring the disclosure of the name of the engagement partner or the name and extent of participation in the audit of other accounting firms or persons in the standards of the PCAOB, standards of Auditing...
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Báo cáo khoa học: A strategy for the generation of specific human antibodies by directed evolution and phage display An example of a single-chain antibody fragment that neutralizes a major component of scorpion venom docx
... scFvs by shortening the linker from 15 to amino acid residues Neither of the diabodies, 3F or C1, was able to neutralize the toxin in the protection assay They did not have the required affinity and ... order to characterize them as soluble proteins Characterization of clones 3F and C1 To discover whether the selected antibodies had the ability to protect mice against the toxic effects of Cn2, ... ratio of toxin -to- antibody fragment Two LD50 of whole venom were also tested using the same quantity of antibody as the one used to neutralize LD50 of toxin All the mice injected with the antibody...
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báo cáo hóa học: " Measurement properties of the Dizziness Handicap Inventory by cross-sectional and longitudinal designs" docx
... discrimination; and ROC ≥ 0.9 outstanding discrimination The best cutoff point of scores was identified, where the sum of the percentages of misclassified participants was lowest [52] We hypothesized that the ... reliability of the Dutch version of the Dizziness Handicap Inventory B-ENT 2006, 2:75-80 Asmundson GJG, Stein MB, Ireland D: A factor analytic study of the dizziness handicap inventory: does it ... satisfactory measurement properties After translating the DHI into Norwegian, the aim of the present study was to examine reliability and validity of the translated version, which was to be used...
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The Project Gutenberg EBook of Evolution in Modern Thought, by Ernst Haeckel and J. Arthur Thomson ppt
... rendered to the theory of organic evolution (I) As everyone knows, the general idea of the Doctrine of Descent is that the plants and animals of the present day are the lineal descendants of ancestors ... Natural History in the widest sense, we rank the picture which Darwin gave to the world of the web of life, that is to say, of the inter-relations and linkages in Nature For the Biology of the individual—if ... real—visions of the web of life, of the fountain of change within the organism, of the struggle for existence and its winnowing, and of the spreading genealogical tree Because, in the second place,...
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Báo cáo khoa học: " The cross-reactivity of the enterovirus 71 to human brain tissue and identification of the cross-reactivity related fragments" ppsx
... 2A), and the nearby Page of 10 fragments in a functional gene have 12 to 39 bp overlap to avoid the miss of epitope EV71 of Fuyang-0805 strain isolated from Anhui province of China was used as the ... College All the mice were bred in an AAALAC-accredited facility and the use of animals was approved by the Animal Care and Use Committee of the Institute of Laboratory Animal Science of Peking ... infection increases the in vivo capacity of peripheral monocytes to cross the blood-brain barrier into the brain and the in vivo sensitivity of the blood-brain barrier to disruption by lipopolysaccharide...
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Báo cáo y học: " Level and course of FEV1 in relation to polymorphisms in NFE2L2 and KEAP1 in the general population" pps
... effect of the KEAP1 SNP on the level of FEV1 (p = 0.0008) as compared to the pooled analysis in the two Dutch cohorts (p = 0.003, table 4) The p value of the additive and detrimental effect of the ... authors thank the participants of the Doetinchem and Vlagtwedde/Vlaardingen studies for their loyal participation every survey The authors thank the staff of the genotyping unit of the Centre for ... cohorts) SNPs in NFE2L2 and KEAP1 and course of FEV1 We did not observe any significant effect of SNPs in NFE2L2 and/ or KEAP1 on the course of FEV1 in either of the cohorts nor in the pooled cohort...
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Báo cáo khoa học: " An Investigation of the Ability of the Glutaraldehyde Test to Distinguish between Acute and Chronic Inflammatory Disease in Horses" ppsx
... scand vol 46 no 1-2, 2005 colostrumopname bij veulens (A study of the reliability of the glutaraldehyde test to determine the level of gamma globulin in the serum of foals and the suitability of ... further laboratory analysis of blood to determine chronicity and etiology of the disease If the test is negative, the disease is most likely acute or the systemic inflammatory response is either ... 1989) The purpose of this clinical trial was to determine the ability of GT to distinguish between acute and chronic inflammatory disease in horses During the trial we compared indicators of inflammation...
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Báo cáo y học: "Consistent dissection of the protein interaction network by combining global and local metrics" ppt
... grouped into one cluster; the TFIIA complex, the Elongator complex, the SAGA histone acetyltransferase complex, and the TFIID complex are grouped into one cluster; and the COMPASS complex and the mRNA ... 100 Figure Robustness of the algorithms to random edge addition and removal Robustness of the algorithms to random edge addition and removal Each curve represents the value of accuracy (left panels) ... complexes and tends to group them together The quality of modules obtained using the GN algorithm is not as good; members of four functional modules, transcription factor IIA (TFIIA) [TOA1, TOA2],...
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WHAT’S NEXT ; Unconventional Wisdomon the Future of the World Economy Edited by David Hale and Lyric Hughes Hale
... losses Andrew Sheng offers the case for a Tobin tax to finance global public goods He reviews the origin of the idea in the 1970s and the recent proposal of it by Lord Adair Turner of the Financial ... because of the influx of people into the province due to the strength in the energy sector in recent years A combination of institutional and regulatory factors prevented the development in Canada of ... and the PAN He lost, by the narrowest of margins, because he was unable to move to the center in the latter stages of the campaign, and Calderón was able to present him as a clear threat to the...
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An investigation of the effects of SFAS no 121 on asset impairment reporting and stock returns
... earnings and returns The frequency and dollar value of asset writedowns made the FASB and the Securities and Exchange Commission (SEC) consider a new standard to guide the recording of impairment of ... description of the impaired assets and the facts and circumstances leading to the writedown; • The amount of the impairment loss and how fair value was determined; 22 • The caption in the income ... used to a longlived asset that an entity expects to sell or otherwise dispose of if the entity has not yet committed to a plan to sell or otherwise dispose of the asset How to determine whether there...
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A study of conditional sentences in the novel jane eyre by charlotte bronte and their vietnamese equivalents
... and then to provide Vietnamese learners with the deeper understanding of English conditional sentences and some ways to help them overcome the difficulties in translating them Objectives of the ... Structure of Thesis Chapter I: Introduction Provides rationale of the study, research problems, aims and objectives of the research, the significance of the study and the scope of the research. ... types N = the number The writer computed the conditional sentences percentage and classified them into the standard of the levels 3.3 Summary of the chapter The research was qualitative and quantitative...
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Tài liệu The Little Guide To Beating Procrastination, Perfectionism and Blocks: A Manual for Artists, Activists, Entrepreneurs, Academics and Other Ambitious Dreamers docx
... even know why I bother to try. And this town it’s full of jerks. They’re too dumb to appreciate real music, and they’re cheap, too I only sold two CDs. And the club manager must think I’m a jerk, too. I’m sure he’ll never let me perform ... even know why I bother to try. And this townit’s full of jerks. They’re too dumb to appreciate real music, and they’re cheap, too – I only sold two CDs. And the club manager must think I’m a jerk, too. I’m sure he’ll never let me perform there ... neutral mood that allows them to continue to do their work. Procrastinators cannot: they panic, and their panic amplifies their fear and anxiety until they can no longer function. Then they retreat into escapist behaviors such as perfectionism, negativity and ...
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No Holds Barred Fighting: The Ultimate Guide to Conditioning Elite Exercises and Training for NHB Competition and Total Fitness pot
... push-ups Starting from the top of the exercise, we descend to brush our chest to the floor for a count of and return to the top of the exercise for a count of Push-ups are, therefore, a 2-count ... touch the toes of the left foot with the right hand — Count ● Twist and touch the toes of the right foot with the left hand — Count 45 Warm-up Fore and aft bends ● Stand upright with hands on hips ... toes of the right foot with the left hand — Count ● Return to upright and fling — Count 44 Chapter 2-count windmill ● Bend forward at the waist and remain there throughout ● Twist and touch the toes...
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ENLISTING THE ARMED FORCES TO PROTECT REPRODUCTIVE HEALTH AND RIGHTS: LESSONS LEARNED FROM NINE COUNTRIES ppt
... Unfortunately, the choice of the department often reflects the history of the project and its previous entry points, rather than a well thought-out strategy The choice of lead departments to manage the ... how to positively engage men to take charge of their own reproductive and sexual well-being and support that of their partners One of the fundamental lessons is to reach out to men where they ... within the military, and between the military and civilian sectors and communities; Adaptation of these guidelines to the specific needs and characteristics of different military forces and groups,...
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Regional Food Hub Resource Guide: Food hub impacts on regional food systems, and the resources available to support their growth and development pdf
... enhances the profitability of our farms We— the grower members—own the business, set its policies, and share in the profits By planning our crops together, by pooling our produce, and by sharing the ... razorthin, and the vagaries of the weather can have a decisive impact on the success or failure of the business The operator of one of the longest standing producerowned food hubs in the United States ... Food hub communities of practice at the local and regional level are starting to emerge and have the benefit of bringing to the table a set of stakeholders who can work together and engage in business...
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The Human Embryo Edited by Shigehito Yamada and Tetsuya Takakuwa doc
... form the forehead (frontal part of the FNP) and the primordial mouth and nose (nasal part of the FNP) By the end of the 4th developmental week, nasal placodes (thickening of surface ectoderm to ... from the first pharyngeal groove At the early period of ear development, the external ears are located in the neck region, and they ascend to the side of the head at the level of the eyes as the ... diameter and is surrounded by the zona pellucida The second maturation division of the oocyte completes as the sperm penetrates the egg (fertilization) The sperm head and the nucleus of the oocyte then...
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the complete guide to relieving cancer pain and suffering may 2004
... and preferences Oncologists (cancer specialists) use a shorthand to pull these characteristics together and define a tumor's stage and site: TO to T4 to rate the size of a primary tumor, NO to ... especially in the chest area, their ability to breathe deeply and cough is inhibited by their pain The careful use of opioids in this setting allows patients to breathe more efficiently and clear their ... obligated to "build the character" of the patient by withholding adequate pain relief The other side of the coin is patients who don't seek relief for their pain because they "don't want to be a bother"...
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the oxford introduction to proto-indo-european and the proto-indo-european world nov 2006
... some of the commonest grammatical elements of Proto-Indo-European, survey the methods used to reconstruct the mythology of the Proto-Indo-Europeans, and examine the various attempts at locating the ... Introduction The Oxford Introduction to Proto-Indo-European and The Proto-Indo-European World Wlls the need for a relatively concise introduction to the full range of reconstructed vocabulary of the language ... understanding of Proto-Indo-European The book is broadly divided into two parts The Wrst, aimed principally at the Wrst group of readers, gives concise introductions to: the discovery and composition of the...
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The Gauge Block Handbook by Ted Doiron and John Beers_1 potx
... This handbook is a both a description of the current practice at the National Institute of Standards and Technology, and a compilation of the theory and lore of gauge block calibration Most of the ... gauge, and the required accuracy of the gauge is 0.5 µm If the size of the gauge requires a stack of five blocks to make up the nominal size of the gauge the accuracy of each block must be known to ... block are made of the same material and have the same surface finish, then the light will penetrate equally into the block top surface and the reference plane, and the errors cancel If the block length...
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