construction structure and dynamics of post transcriptional regulatory network directed by rna binding proteins
Tài liệu Báo cáo khoa học: Modulation of cyclin D1 and early growth response factor-1 gene expression in interleukin-1b-treated rat smooth muscle cells by n-6 and n-3 polyunsaturated fatty acids pdf
... synthesis and hyperphosphorylation of Rb by n-3 and n-6 PUFAs Induction of cyclin D1 is one of the earliest effects of mitogenic factors leading to cell cycle re-entry, G1-phase progression, and transition ... transduction induced by PDGF [15], serotonin [16] and thromboxane [17] As Cdk2 activity is a key event of the G1-S transition, the inhibition of Cdk2 phosphorylation and activity by EPA and DHA may explain ... the production of PGE2 [18] The inhibition of PGE2 release was the consequence of a reduction of COX-2 and secretory PLA2 mRNA expression Moreover, the IL-1b-induced expression of secretory PLA2...
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Báo cáo khoa học: "Overexpression of cyclin D1 and cyclin E in 1,2-dimethylhydrazine dihydrochloride-induced rat colon carcinogenesis" potx
... cyclin E and PCNA mRNA expression levels of adenomas and Fig Quantitation of cyclin D1, cyclin E and PCNA mRNA expression by quantitative RT-PCR analysis Bars represent levels of incorporation of [α-32P]dCTP ... cyclin E and PCNA PCR products after normalization to HPRT, by measuring the radioactivity (c.p.m.) of each band in Figure Results quoted are the mean ± SE of each group of tissues mRNA levels of (A) ... cyclin D1, cyclin E and PCNA in each stage, as quantified by measuring the radioactivity of each band, are shown in Figure The mRNA levels of cyclin D1 (Fig 2A), cyclin E (Fig 2B) and PCNA (Fig 2C)...
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Báo cáo khoa học: " The ATM and ATR inhibitors CGK733 and caffeine suppress cyclin D1 levels and inhibit cell proliferation" ppsx
... X-100 and a cocktail of protease inhibitors (Roche Diagnostics Scandinavia AB, Bromma, Sweden)] on ice for 30 Lysates were clarified by centrifugation (13,000 rpm for 15 at 4°C) and the supernatants ... of cyclin D1 levels within h of exposure, and this effect was maximal between and h after exposure (Figure 1A) CGK733 induced the loss of cyclin D1 expression at concentrations as low as μM and ... Identification and characterization of a novel and specific inhibitor of the ataxia-telangiectasia mutated kinase ATM Cancer Res 2004, 64:9152-9159 Cowell IG, Durkacz BW, Tilby MJ: Sensitization of breast...
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báo cáo khoa học: " Downregulation of CDKN2A and suppression of cyclin D1 gene expressions in malignant gliomas" doc
... effect of CDKN2A on cell cycle by overexpression of CDKN2A in vitro Overexpression of CDKN2A suppresses colony-forming ability and growth rate of human malignant glioma cells However, knockdown of ... phosphorylation of pRb and expression of cyclin D1 in T98G, U87-MG and SW1783 glioma cell lines transfected with CDKN2A (A) However, knockdown of CDKN2A increased the phosphorylation of pRb and cyclin ... serum (GIBCO) and mM glutamine Page of cleavage sites (EcoRI and BamH I), and cloned into pcDNA3.1 vector (Invitrogen) Small interfering RNA (siRNA) knockdown of CDKN2A Immunohistochemistry Paraffin-embedded...
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báo cáo khoa học: " Galectin-3 and cyclin D1 expression in non-small cell lung cancer" doc
... significance of the expression of proteins involved in regulation of cell proliferation remains promising Cellular proliferation is regulated by protein complexes composed of cyclins and cyclin-dependent ... (cdks) Five major families of cyclins (termed A, B, C, D, and E) have been isolated and characterized Cyclin D1 reaches it peak of synthesis and activity during the G1 phase, and is believed to regulate ... [11] The expression of cyclin D1 and other cyclins has been often evaluated in many cancers and its prognostic value is disputable Page of In esophageal squamous cell carcinoma and hepatocellular...
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Báo cáo y học: "RhoA signaling modulates cyclin D1 expression in human lung fibroblasts; implications for idiopathic pulmonary fibrosis" ppsx
... function is facilitated through binding and activation of cyclin-dependent kinases (CDK) and 6, with phosphorylation of the retinoblastoma protein (Rb), and release of sequestered transcription ... from IPF patients (HIPF, LL29, and LL97a) and normal control equivalents CCD8LU Quantification of mRNA was performed by determining the threshold cycle; and standard curves were constructed using ... underpinned by erratic deposition of extracellular matrix (ECM) proteins and progressive lung tissue remodelling Although a number of scientific advances have been made in understanding disease...
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De khao sat dau nam Đ1
... thanks B I am ten C She is ten 16 What is that? – It is …… pen A a B an C the 17 This is …… desk And that is your desk A she B he C you 18 Is that ……………….pencil? – Yes, it is A you B your C she...
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ĐỀ THI TUYỂN SINH CAO ĐẲNG NĂM 2013 Môn TIẾNG ANH Khối A1 và Khối D1
... which of the following provides energy for the body? A Proteins, vitamins, and carbohydrates B Proteins, fats, and minerals D Carbohydrates, minerals, and water C Carbohydrates, proteins, and fats ... which of the following provides energy for the body? A Carbohydrates, proteins, and fats B Proteins, fats, and minerals C Proteins, vitamins, and carbohydrates D Carbohydrates, minerals, and water ... friendly and professional B both professional or friendly D neither professional or friendly C either friendly nor professional Question 10: Twenty thousand years ago, a sheet of ice a thousand meters...
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ĐỀ THI TUYỂN SINH CAO ĐẲNG NĂM 2012 Môn: TIẾNG ANH; Khối A1 và Khối D1 mã 137
... In the past, we had less news of distant people and lands because A printing, transportation, and telecommunications were not developed B means of communication and transportation were not ... a hundred channels News is the subject of many of those channels, and on several of them it runs 24 hours a day What’s more, after the traumatic events of September 11, 2001, live newscasts were ... place to place, and the less news we had of distant people and lands altogether The printing press obviously changed all that, as did every subsequent development in transportation and telecommunication...
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ĐỀ THI TUYỂN SINH CAO ĐẲNG NĂM 2012 Môn: TIẾNG ANH; Khối A1 và Khối D1 mã 415
... phrase for each of the blanks from 24 to 33 The popular image of student life is of young people with few responsibilities enjoying themselves and (24) very little work This is often not true ... part-time basis while having a job and looking after a family These students are often (26) motivated and work very hard Younger students are often thought to be lazy and careless about money but ... a hundred channels News is the subject of many of those channels, and on several of them it runs 24 hours a day What’s more, after the traumatic events of September 11, 2001, live newscasts were...
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ĐỀ THI TUYỂN SINH CAO ĐẲNG NĂM 2012 Môn: TIẾNG ANH; Khối A1 và Khối D1 mã 532
... news of distant people and lands because A means of communication and transportation were not yet invented B the printing press changed the situation too slowly C printing, transportation, and ... a hundred channels News is the subject of many of those channels, and on several of them it runs 24 hours a day What’s more, after the traumatic events of September 11, 2001, live newscasts were ... perspective is obviously A a source of chronic stress B the result of an overabundance of good news C a source of defects in human brain D the result of human brain’s switch to alarm mode Question...
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ĐỀ THI TUYỂN SINH CAO ĐẲNG NĂM 2012 Môn: TIẾNG ANH; Khối A1 và Khối D1 mã 638
... news of distant people and lands because A means of communication and transportation were not yet invented B most people lived in distant towns and villages C printing, transportation, and ... landfills are polluted B The fewer landfills we have C The more landfills are there D The more polluted landfills will be Question 70: I have two sisters, A one of them are nurses B most of ... a hundred channels News is the subject of many of those channels, and on several of them it runs 24 hours a day What’s more, after the traumatic events of September 11, 2001, live newscasts were...
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ĐỀ THI TUYỂN SINH CAO ĐẲNG NĂM 2012 Môn: TIẾNG ANH; Khối A1 và Khối D1 mã 869
... news of distant people and lands because A means of communication and transportation were not yet invented B the printing press changed the situation too slowly C printing, transportation, and ... increases in the incidence of flooding and of droughts These in turn could have a harmful effect on agriculture It is thought that this unusual warming of the Earth has been caused by so-called greenhouse ... atmosphere by car engines and modern industrial processes, for example Such gases not only add to the pollution of the atmosphere, but also create a greenhouse effect, by which the heat of the sun...
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