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constitutional features of systemic lupus erythematosus

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Báo cáo y học: "The in vivo expression of actin/salt-resistant hyperactive DNase I inhibits the development of anti-ssDNA and anti-histone autoantibodies in a murine model of systemic lupus erythematosus" ppt

Báo cáo khoa học

... H, Mannherz HG, Moroy T: Features of systemic lupus erythematosus in Dnase1-deficient mice Nat Genet 2000, 25:177-181 Walport MJ: Lupus, DNase and defective disposal of cellular debris Nat Genet ... Turler H, Miescher PA: Features of systemic lupus erythematosus in mice injected with bacterial lipopolysaccharides: identificantion of circulating DNA and renal localization of DNA-anti-DNA complexes ... (rhDNase) in patients with lupus nephritis Lupus 1999, 8:68-76 Macanovic M, Sinicropi D, Shak S, Baughman S, Thiru S, Lachmann PJ: The treatment of systemic lupus erythematosus (SLE) in NZB/W...
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Báo cáo y học:

Báo cáo y học: "Effect of dsDNA binding to SmD-derived peptides on clinical accuracy in the diagnosis of systemic lupus erythematosus" potx

Báo cáo khoa học

... for the classification of systemic lupus erythematosus Arthritis Rheum 1982, 25:1271-1277 Brahms H, Raker VA, van Venrooij WJ, Luhrmann R: A major, novel systemic lupus erythematosus autoantibody ... Arbuckle MR, McClain MT, Rubertone MV, Scofield RH, Dennis GJ, James JA, Harley JB: Development of autoantibodies before the clinical onset of systemic lupus erythematosus N Engl J Med 2003, 349:1526-1533 ... Detection of autoantibodies to Sm antigen in systemic lupus erythematosus by immunodiffusion, ELISA and immunoblotting: variability of incidence related to assays and ethnic origin of patients...
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Báo cáo y học:

Báo cáo y học: "Development and management of systemic lupus erythematosus in an HIV-infected man with hepatitis C and B co-infection following interferon therapy: a case report" doc

Báo cáo khoa học

... Hepatitis C virus infection mimicking systemic lupus erythematosus: study of hepatitis C virus infection in a series of 134 Spanish patients with systemic lupus erythematosus Arthritis Rheum 2000, ... Loss of pDC in HIV infection usually parallels the loss of CD4 [15], but the rate of recovery of DC and CD4 T cells may be independent What factors may have been important in the development of ... Akira S, Chang B, Duramad O, Coffman RL: Nucleic acids of mammalian origin can act as endogenous ligands for Toll-like receptors and may promote systemic lupus erythematosus J Exp Med 2005, 202:1131-1139...
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Báo cáo y học:

Báo cáo y học: "Autoantibodies predate the onset of systemic lupus erythematosus in northern Sweden" potx

Báo cáo khoa học

... classification of systemic lupus erythematosus Arthritis Rheum 1982, 25:1271-1277 18 Hochberg MC: Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus ... among AfricanAmerican men with systemic lupus erythematosus Lupus 2003, 12:99-106 Borchers AT, Naguwa SM, Shoenfeld Y, Gershwin ME: The geoepidemiology of systemic lupus erythematosus Autoimmun Rev ... patients with systemic lupus erythematosus Arthritis Rheum 2001, 44:2367-2370 24 Lau CS, Yin G, Mok MY: Ethnic and geographical differences in systemic lupus erythematosus: an overview Lupus 2006,...
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Báo cáo y học: "Correction: Steady-state mycophenolate mofetil pharmacokinetic parameters enable prediction of systemic lupus erythematosus clinical flares: an observational cohort study" potx

Báo cáo khoa học

... 2011, 13:401 http://arthritis-research.com/content/13/2/401 Page of Table Inclusion characteristics (of the 26 systemic lupus erythematosus patients) and their ability to predict clinical outcome ... rate (estimated with the Cockcroft-Gault formula); MMF, mycophenolate mofetil; MPA, mycophenolic acid; MPAG, mycophenolic acid glucuronide; SLEDAI, Systemic Lupus Erythematosus Disease Activity ... (2-2) 0.9 Corticosteroids, mg/day 11 (7-35) 10 (5-20) 15 (7-45) 0.37 Months of MMF therapy (1-3) (1-3) (1-3) 0.56 Months of corticosteroids 10 (6-13) 10 (5-15) (5-14) 0.12 Treatment MMF, g/day MPA...
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Báo cáo y học:

Báo cáo y học: "The VH gene repertoire of splenic B cells and somatic hypermutation in systemic lupus erythematosus" potx

Báo cáo khoa học

... specificity in systemic lupus erythematosus from animal models Clin Exp Immunol 1990, 81:1-4 Stott DI: Spectrotypes of anti-DNA antibodies show that antiDNA-secreting B-cell clones of SLE patients ... binding specificities and idiotype expression of hybridoma derived monoclonal autoantibodies from splenic cells of patients with systemic lupus erythematosus Ann Rheum Dis 1995, 54:471-476 Ravirajan ... distinct mantle zone was observed surrounding either GC Immunohistochemistry of sections from a patient with systemic lupus erythematosus (a) Anti-FDC (follicular dendritic cell) staining within the...
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Báo cáo y học:

Báo cáo y học: "Interactions among type I and type II interferon, tumor necrosis factor, and -estradiol in the regulation of immune response-related gene expressions in systemic lupus erythematosus" potx

Báo cáo khoa học

... of lupus erythematosus patients systemic TNF stimulation on gene expression in healthy individuals Effect of TNF stimulation on gene expression in healthy individuals and and systemic lupus erythematosus ... signatures in systemic lupus erythematosus blood J Exp Med 2003, 197:711-723 Han GM, Chen SL, Shen N, Ye S, Bao CD, Gu YY: Analysis of gene expression profiles in human systemic lupus erythematosus ... patients with systemic lupus erythematosus Clin Exp Immunol 2008, 152:482-487 Tsuchiya N, Kyogoku C: Role of Fc gamma receptor IIb polymorphism in the genetic background of systemic lupus erythematosus: ...
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Báo cáo y học:

Báo cáo y học: "Practical and theoretical barriers to the prevention of accelerated atherosclerosis in systemic lupus erythematosus" docx

Báo cáo khoa học

... with systemic lupus erythematosus Am J Med 1984, 77:286-292 Shome GP, Sakauchi M, Yamane K, Takemura H, Kashiwagi H: Ischemic heart disease in systemic lupus erythematosus A retrospective study of ... and risk factors of carotid plaque in women with systemic lupus erythematosus Arthritis Rheum 1999, 42:51-60 Salmon JE, Roman MJ: Accelerated atherosclerosis in systemic lupus erythematosus: implications ... cardiovascular risk factors in systemic lupus erythematosus J Musculoskel Med 1998, 15: 42-52 El-Magadmi M, Ahmad Y, Wajed J, Bruce IN: The bimodal mortality pattern in systemic lupus erythematosus Curr...
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Báo cáo y học:

Báo cáo y học: "Serum levels of autoantibodies against monomeric C-reactive protein are correlated with disease activity in systemic lupus erythematosus" potx

Báo cáo khoa học

... infectious risk factors for developing systemic lupus erythematosus Arthritis Rheum 1998, 41:1714-1724 Robson MG, Walport MJ: Pathogenesis of systemic lupus erythematosus Clin Exp Allergy 2001, ... T: Features of systemic lupus erythematosus in DNase1-deficient mice Nat Genet 2000, 25:177-181 Emlen W, Niebur J, Kadera R: Accelerated in vitro apoptosis of lymphocytes from patients with systemic ... autoantibody-inducing T cells of lupus J Exp Med 1993, 177:1367-1381 Spronk PE, Limburg PC, Kallenberg CGM: Serological markers of disease activity in systemic lupus erythematosus Lupus 1995, 4:86-94 Gewurz...
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Báo cáo y học:

Báo cáo y học: "Decreased levels of soluble amyloid β-protein precursor and β-amyloid protein in cerebrospinal fluid of patients with systemic lupus erythematosus" ppsx

Báo cáo khoa học

... JG, Michalski JP: Systemic lupus erythematosus and dementia Psychol Rep 1998, 83:1034 Jonsson H, Nived O, Sturfelt G: Outcome in systemic lupus erythematosus: a prospective study of patients from ... TM, Stevens MB: Neuropsychiatric manifestations of systemic lupus erythematosus: diagnosis, clinical spectrum, and relationship to other features of the disease Medicine (Baltimore) 1976, 55:323339 ... in systemic lupus erythematosus with central nervous system involvement Rheumatology (Oxford) 2003, 42:773-777 Sergent JS, Lockshin MD: Editorial: treatment of central nervous system lupus erythematosus...
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Báo cáo y học:

Báo cáo y học: "Analysis of HLA DR, HLA DQ, C4A, FcγRIIa, FcγRIIIa, MBL, and IL-1Ra allelic variants in Caucasian systemic lupus erythematosus patients suggests an effect of the combined FcγRIIa R/R and IL-1Ra 2/2 genotypes on disease susceptibility" pptx

Báo cáo khoa học

... classification of systemic lupus erythematosus Arthritis Rheum 1982, 25:1271-1277 16 Jonsson H, Nived O, Sturfelt G: Outcome in systemic lupus erythematosus: a prospective study of patients from ... development and initial validation of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index for systemic lupus erythematosus Arthritis Rheum 1996, ... of twin concordance in systemic lupus erythematosus Arthritis Rheum 1992, 35:311-318 Truedsson L, Sturfelt G, Johansen P, Nived O, Thuresson B: Sharing of MHC haplotypes among patients with systemic...
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Báo cáo y học:

Báo cáo y học: "Commentary on “Genetic linkage and transmission disequilibrium of marker haplotypes at chromosome 1q41 in human systemic lupus erythematosus”, by RR Graham et al" pdf

Báo cáo khoa học

... Lockshin MD, D’Angelo WA, Christian CL: Studies of twins with systemic lupus erythematosus: A review of the literature and presentation of 12 additional sets Am J Med 1975, 59:533-552 Deapen D, Escalante ... estimate of twin concordance in systemic lupus erythematosus Arthritis Rheum 1992, 35:311-318 Arthritis Research 10 11 12 13 14 15 Vol No Barton and Worthington Vyse TJ, Todd JA: Genetic analysis of ... Kimberly RP, Neas BR, Rich SS, Behrens TW, Harley JB: Genome scan of human systemic lupus erythematosus by regression modelling Evidence of linkage and epistasis at 4p16-15.2 Am J Hum Genet 2000, 67:1460-1469...
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Báo cáo y học:

Báo cáo y học: "Screening of an endothelial cDNA library identifies the C-terminal region of Nedd5 as a novel autoantigen in systemic lupus erythematosus with psychiatric manifestations" ppt

Báo cáo khoa học

... were not statistically significant SLE, systemic lupus erythematosus; SLEDAI, Systemic Lupus Erythematosus Disease Activity Index (47%) of 17, vs (17%) of 34, P = 0.045 on the Fisher exact test) ... ization of the C-terminal region of Nedd5 Nucleotide and amino acid sequences and immunochemical characterization of the C-terminal region of Nedd5 (a) The nucleotide sequence of 335 base pairs of ... and the presence of AECAs), of patients with infectious mononucleosis, and of healthy subjects Finally, we investigated by immunofluorescence the intracellular redistribution of Nedd5 in endothelial...
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Báo cáo y học:

Báo cáo y học: "Differential expression of chemokine receptors on peripheral blood B cells from patients with rheumatoid arthritis and systemic lupus erythematosus" ppsx

Báo cáo khoa học

... of B cell migration, we analyzed chemokine receptor expression on peripheral blood B cells Expression profiles of patients with RA were compared with those from patients with systemic lupus erythematosus ... concentrations in sera Sera of healthy controls and of sera patients with rheumatoid arthritis, systemic lupus erythematosus and osteoarthritis were tested in a standard ELISA test A D450 of 0.06 corresponds ... groups of patients [30] Lower levels of chemokine receptor CXCR5 and higher levels of CXCR3 on peripheral blood B cells may represent a generalized change in the profile and might be seen on all of...
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Báo cáo y học:

Báo cáo y học: "Expression and function of inducible co-stimulator in patients with systemic lupus erythematosus: possible involvement in excessive interferon-γ and anti-double-stranded DNA antibody production" pot

Báo cáo khoa học

... progression of systemic autoimmunity Ann N Y Acad Sci 2003, 987:236-239 Theofilopoulos AN, Koundouris S, Kono DH, Lawson BR: The role of IFN-gamma in systemic lupus erythematosus: a challenge Page 13 of ... classification of systemic lupus erythematosus Arthritis Rheum 1982, 25:1271-1277 Bombardier C, Gladman DD, Urowitz MB, Caron D, Chang CH: Derivation of the SLEDAI A disease activity index for lupus patients ... coordination of the study All authors read and approved the final manuscript 17 18 19 20 21 References 10 11 12 13 14 15 16 Hahn BH: An overview of the pathogenesis of systemic lupus erythematosus...
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Báo cáo y học:

Báo cáo y học: "Activation of transforming growth factor-β1 and early atherosclerosis in systemic lupus erythematosus" pptx

Báo cáo khoa học

... O, et al.: The reliability of the Systemic Lupus International Collaborating Clinics/American College of Rheumatology Damage Index in patients with systemic lupus erythematosus Arthritis Rheum ... down-regulation of B cell activity in SLE: effects of interleukin-2 and transforming growth factor-beta Lupus 1999, 8:95-102 Bruce IN, Gladman DD, Urowitz MB: Premature atherosclerosis in systemic lupus erythematosus ... Schneider M: High levels of circulating early apoptic peripheral blood mononuclear cells in systemic lupus erythematosus Lupus 1998, 7:113-118 24 Gergely P Jr, Niland B, Gonchoroff N, Pullmann R Jr,...
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Báo cáo y học:

Báo cáo y học: "Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus" ppsx

Báo cáo khoa học

... Figure Development of infiltrates and inflammatory lesions in the vicinity of sunburn cells (SBCs) in patients with systemic lupus erythematosus (SLE) Haepatients with systemic lupus erythematosus ... expression of photosensitivity in systemic lupus erythematosus Ann Rheum Dis 1989, 48:461-463 Bijl M, Limburg PC, Kallenberg CG: New insights into the pathogenesis of systemic lupus erythematosus ... LM, Reveille JD: Systemic lupus erythematosus in three ethnic groups XIX Natural history of the accrual of the American College of Rheumatology criteria prior to the occurrence of criteria diagnosis...
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Báo cáo y học:

Báo cáo y học: "Is disturbed clearance of apoptotic keratinocytes responsible for UVB-induced inflammatory skin lesions in systemic lupus erythematosus" pot

Báo cáo khoa học

... the use of the Amaxa Human Dermal Fibroblast Nucleofactor kit (NHDFadult) with program U-23 for human FLS Murine FLS were transfected with the use of the Mouse Embryonic Fibroblasts Page of (page ... The percentage of cells with detectable p53 protein was 75.1 ± 2.9% for scrambled siRNA, 2.8 ± 0.6% for µg of p53 siRNA, and 0.9 ± 0.5% for µg of p53 siRNA Functional effects of p53 deficiency ... Hummel KM, Jeisy E, Gay R, Gay S: Activation of synovial fibroblasts in rheumatoid arthritis: lack of expression of the tumour suppressor PTEN at sites of invasive growth and destruction Arthritis...
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Báo cáo y học:

Báo cáo y học: "Association of the diplotype configuration at the N-acetyltransferase 2 gene with adverse events with co-trimoxazole in Japanese patients with systemic lupus erythematosus" pps

Báo cáo khoa học

... classification of systemic lupus erythematosus Arthritis Rheum 1982, 25:1271-1277 20 Hochberg MC: Updating the American College of Rheumatology revised criteria for the classification of systemic lupus erythematosus ... of serum ALT in fast acetylators and slow acetylators There acetylators were 47 fast acetylators and seven slow acetylators in the cohort Levels of serum ALT in patients with systemic lupus erythematosus ... coordination of the study MK was responsible for using PENHAPLO software Y Katsumata, KT, AN, TM and AM recruited a subset of patients MH recruited a subset of patients and participated in coordination of...
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