citalopram an antagonist antidepressant discovered by a rational approach
Báo cáo toán học: "Tilings by translation: enumeration by a rational language approach" pdf
... that X starts and ends with a 1, and Y starts and ends with a Proof By Proposition 3.1 the upper and the lower paths of P can be decomposed as U = XY , and L = Y X, respectively Since P is a parallelogram ... begins with a south step and ends with an east one Moreover, by definition of the class H, [B, C] and [D, E] cannot be empty paths, and consequently also [A, B] and [C, D] contain at least one step ... pseudo-square parallelogram polyominoes We would like also to thank P Flajolet and M BousquetM´lou for many clear explanations and suggestions e References [1] G Barequet, M Moffie, A Rib´ and G Rote,...
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preparation of fe2o3 submicro - flowers by a hydrothermal approach
... through a hydrothermal method using Span80 or L113B as a soft template [17] Wan et al have proposed a soft-template-assisted hydrothermal route to prepare single crystal nanorods with an average diameter ... volume variation of nanometer particles is much smaller than large size particles during charge–discharge cycles, and nanometer materials often have higher plasticity and deformability Those factors ... primary nanoparticles, are resulted from the small particle size and high surface area, and the high uniformity and good dispersion also share some credit [1] X.W Wang, Zh.Y Zhang, Sh.X Zhou, Mater...
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Báo cáo hóa học: " Updated survivals and prognostic factor analysis in myeloma treated by a staged approach use of bortezomib/thalidomide/dexamethasone in transplant eligible patients" pot
... IgG/kappa from a single IgG/kappa, and two patients had complete change of paraprotein (one from IgA/kappa to IgG kappa, and one from IgD/lambda to IgG/kappa) Statistical analysis OS was defined as ... S, Jagannath S, Irwin D, Rajkumar SV, Srkalovic G, Alsina M, Alexanian R, Siegel D, Orlowski RZ, Kuter D, Limentani SA, Lee S, Hideshima T, Esseltine DL, Kauffman M, Adams J, Schenkein DP, Anderson ... Garc a- Lara a J, Martínez-Martínez R, Hernández-Garc a MT, Carrera D, Besalduch J, de Arriba F, Ribera JM, Escoda L, Hernández-Ruiz B, Garc a- Frade J, Rivas-González C, Alegre A, Bladé J, San...
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Báo cáo y học: " Management of deep neck infection by a transnasal approach: a case report" ppsx
... patient did not have airway obstruction To date, only a small number of patients have been treated by the transnasal endoscopic approach Endoscopic approaches have a number of important advantages ... children: a new approach to diagnosis and treatment Laryngoscope 1997, 107:1627-1634 Nicolai P, Lombardi D, Berlucchi M, Farina D, Zanetti D: Drainage of retro-parapharyngeal abscess: an additional ... perform a transcervical procedure under general anesthesia due to severe DM, severe inflammation, and trismus In addition, an external approach under local anesthesia was considered difficult because...
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Báo cáo y học: "A rational approach to cancer therapy" pot
... loss of BRCA1/2, is overwhelmed by the combination of a chemotherapeutic agent that causes DNA damage and a compound that prevents DNA repair through an alternative pathway, in this case base excision ... protein, appears to have sufficient function to restore DNA repair and enable resistance Similar deletions were identified in ovarian cancer patients with resistance to carboplatin Ashworth also addressed ... shape, for example Understanding of pathways leading to targeted and combination therapies How biochemical pathways can be used to find new therapeutics was illustrated by David Lane (University...
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Báo cáo khoa học: "An Automatic Method for Summary Evaluation Using Multiple Evaluation Results by a Manual Method" pptx
... 419–426 Kenji Yasuda, Fumiaki Sugaya, Toshiyuki Takezawa, Seiichi Yamamoto and Masuzo Yanagida 2003 Applications of Automatic Evaluation Methods to Measuring a Capability of Speech Translation System ... 10 summaries in a dataset were selected, and ranked by Yasuda’s method Then, Yasuda’s method was evaluated using Precision Two summaries were also ranked by ROUGE and by cosine distance and both ... and asked them to translate 23 Japanese conversations into English They also generated translations using a system for each conversation Then, they evaluated both translations using an automatic...
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Báo cáo hóa học: " Development and application of a biomarker assay for determining the pharmacodynamic activity of an antagonist candidate biotherapeutic antibody to IL21R in whole blood" pptx
... or pair housed and cared for according to the American Association for Accreditation of Laboratory Animal Care guidelines The Wyeth Institutional Animal Arai et al Journal of Translational Medicine ... this basic approach (ex vivo stimulation of whole blood) to develop pharmacodynamic biomarker assays for a candidate therapeutic antibody, Ab-01 Ab-01, a human antibody generated by phage display, ... humans and monkeys that identified the candidate biomarkers, and they participated in the data analyses AAH developed the customized Spotfire tool used for data analyses and reviewed statistical...
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Báo cáo hóa học: " Magnetotransport in an aluminum thin film on a GaAs substrate grown by molecular beam epitaxy" ppt
... the AFM and X-Ray measurements All authors read and approved the final manuscript Author details Department of Physics, National Taiwan University, No 1, Sec 4, Roosevelt Rd Taipei 106, Taiwan ... twodimensional channels Appl Phys Lett 2007, 91:083510 Davis JA, Venkatesan R, Kaloyeros A, Beylansky M, Souri SJ, Banerjee K, Saraswat KC, Rahman A, Reif R, Meindl JD: Interconnect limits on gigascale ... August 2010 Accepted: 26 January 2011 Published: 26 January 2011 References Liu HF, Chua Sh, Xiang N: Growth-temperature- and thermal-annealinduced crystalline reorientation of aluminum on GaAs...
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measurement and comparison of credit risk by a markov chain an empirical investigation of bank loans in taiwan
... loans always longer than unsecured loans Loan rate Panel A Secured loans Maximum Minimum Mean Standard deviation Kurtosis Skewness Panel B Unsecured loans Maximum Minimum Mean Standard deviation ... Standard and Poor’s rating, defaulting in a given period is a rare event Although there are no transitions from AAA to default, there are transitions from AAA to AA and from AA to default As a result, ... normal The 28 domestic banks include: (1) Agricultural Bank of Taiwan; (2) Bank of Taiwan; (3) Bank of Overseas Chinese; (4) Bank of Sinopac Company Ltd.; (5) Bowa Bank; (6) Cathay United Bank;...
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Báo cáo toán học: "Permutations generated by a stack of depth 2 and an infinite stack in series" potx
... followed by an infinite stack We prove that the algorithm is valid, and that a permutation is accepted if and only if it can be generated by the stacks, if and only if it avoids the 20 permutations ... Theorem Let σ be a permutation The following are equivalent σ can be generated by a stack of depth two and an infinite stack σ can be generated by Algorithm σ avoids the set of 20 permutations B the ... permutation containing one can be generated It is routine to check by hand or computer that each of the permutations in B cannot be generated by a stack of depth two followed by an infinite stack...
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Báo cáo toán học: "Minimum rank of matrices described by a graph or pattern over the rational, real and complex numbers" doc
... the nullspace of A By Lemma 2.1, CS1 contains a submatrix that is a by permutation matrix Thus, rank (A) = (and so W has columns) Note that since dim row (A) = rank (A) = = − rank(W ), row (A) = LNS(W ... pattern of A By Corollary 2.7 there is no rational matrix with sign pattern Z of rank Hence the minimum rank among the rational matrices with sign pattern Z is larger than the minimum rank among ... Proof By Lemma 2.2, mr(MCS ) = C Let A be a real realization of CS1 of minimum rank We claim that rank (A) ≥ Suppose to the contrary that rank (A) ≤ Let W be a real matrix whose columns form a basis...
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Báo cáo y học: "A comparative study of the inhibitory effects of interleukin-1 receptor antagonist following administration as a recombinant protein or by gene transfer." pps
... Recombinant human IL-1Ra and human IL-1Ra synthesized transgenically in mammalian cells are equipotent antagonists of human IL-1β Our data indicate that the greater efficiency noted for transgenic ... triplicate, and each data point represents the mean value ± SD ELISA = enzyme-linked immunosorbent assay; HSF, human synovial fibroblast; IL-1Ra, IL-1 receptor antagonist; PGE2, prostaglandin E2 and ... gene transfer in the treatment of chronic articular disease Indeed, IL-1Ra gene therapy has demonstrated impressive efficacy in animal models of RA and OA, and a phase I human trial has recently...
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Báo cáo khoa học: " Intensity Modulated Radiotherapy (IMRT) in the postoperative treatment of an adenocarcinoma of the endometrium complicated by a pelvic kidney" pot
... reports of auto-transplantation followed by RT for inguinal-pelvic irradiation in a vulvar cancer patient, and for adjuvant treatment of a stage III operated rectal adenocarcinoma exists [4,5] Although ... Salvage of a kidney graft in a patient with advanced carcinoma of the cervix by reimplantation of the graft from the pelvis to the upper abdomen in preparation for radiation therapy Transplantation ... functional biochemical exams Benefit of adjuvant radiation and chemotherapy The standard surgical treatment for uterine neoplasia consists of Radical Hysterectomy, bilateral salpingo oophorectomy, and...
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Báo cáo y học: "Protease inhibitor-induced nausea and vomiting is attenuated by a peripherally acting, opioid-receptor antagonist in a rat model" doc
... plasma samples was approximately ng/mL (100 pg/injection) Statistical analysis Data were analyzed with a two-way analysis of variance (ANOVA) with group and time as the two factors Statistical ... Takeda N, Hasegawa S, Morita M, Horii A, Uno A, Yamatodani A, Matsunaga T: Neuropharmacological mechanisms of emesis I Effects of antiemetic drugs on motion- and apomorphineinduced pica in rats ... morphine-induced analgesia in rats subjected to the radiant-heat tail-flick assay, and morphine-induced reduction in gastrointestinal tract movement was antagonized by the compound in a dose-related manner...
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Báo cáo y học: " Foreign body granuloma in the anterior abdominal wall mimicking an acute appendicular lump and induced by a translocated copper-T intrauterine contraceptive device: a case report" docx
... of iatrogenic perforation and migration Afr J Reprod Health 2003, 7(3):117-123 Mittal S, Gupta I, Lata P, Mahajan U, Gupta AN: Management of translocated and incarcerated intrauterine contraceptive ... for anesthesia and postoperative recovery Critical review and submission was carried out by SHH All five authors read and approved the final manuscript References Ohana E, Sheiner E, Leron E, Mazor ... Appendix perforation by an intrauterine contraceptive device Eur J Obstet Gynecol Reprod Biol 2000, 88:129-131 Katara AN, Chandiramani VA, Pandya SM, Nair NS: Migration of intrauterine contraceptive...
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Báo cáo y học: " A patient with bacteraemia and possible endocarditis caused by a recently-discovered genomospecies of Capnocytophaga: Capnocytophaga genomospecies AHN8471: a case report" potx
... conventional surgical drainage and produced a similar outcome Moreover, percutaneous catheter drainage areas are less likely to become secondarily infected by antibiotic-resistant bacteria, and it ... carotid sheaths In 2b (after days of antibiotic therapy), the appearance of the disease process has changed (in comparison to 2a) with a decreasing amount of air in the soft tissues and replacement ... temperature came down and his oral intake improved but over the next days a tender and fluctuant swelling appeared in the suprasternal region with diffuse margins A repeat CT scan of the neck and...
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Báo cáo y học: " A patient with bacteraemia and possible endocarditis caused by a recently-discovered genomospecies of Capnocytophaga: Capnocytophaga genomospecies AHN8471: a case report" pps
... tumour Although he was being treated for endocarditis, and would have thus warranted more prolonged intravenous antibiotic therapy, his malignancy was at such an advanced stage that he was discharged ... days incubation Gram-negative rods were isolated from both aerobic and anaerobic Our case shows again the potential for Capnocytophaga to cause bacteraemia and systemic illness in humans Patients ... man was referred urgently to hospital with a 2-month history of dysphagia, anorexia, nausea, significant weight loss (greater than 15 kg), general fatigue and insomnia He also reported a 3-day...
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Báo cáo y học: "The effectiveness of hand-disinfection by a flow water system using electrolytic products of sodium chloride, compared with a conventional method using alcoholic solution in an" ppt
... et al Critical Care 1998, 2:79 http://ccforum.com number of bacteria after hand-washing/the number of bacteria before hand-washing)] Values are calculated from raw data and expressed as mean ... Microbial Diseases, Osaka University, Yamadaoka, Suita, Osaka 565, Japan Published: 22 May 1998 References Doebbeling BN, Stanely GL, Sheetz CT, et al: Comparative efficacy of alternative hand-washing ... Each value was analysed using Mann-Whitney (between two groups) or anlaysis of variance (ANOVA; among three groups) tests Statistical significance was considered at P < 0.05 The number of bacteria...
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Báo cáo y học: "An N-terminally truncated envelope protein encoded by a human" ppt
... the causes and treatment of multiple sclerosis Nature 1999, 399 :A4 0 -A4 7 Komurian-Pradel F, Paranhos-Baccala G, Bedin F, Ounanian-Paraz A, Sodoyer M, Ott C, Rajoharison A, Garcia E, Mallet F, Mandrand ... with mAb 6A2 B2 on human placenta (A) and an acute MS lesion (B) Arrowheads in A point to syncytiotrophoblast cell layer Strong staining with 6A2 B2 was seen in a case of fulminant MS in activated ... and KR carried out the experimental work CC, SW, GL, JM, and KR analyzed the data CS carried out and analyzed the immunohistochemical studies KR drafted the manuscript All authors read and approved...
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Báo cáo y học: "NGAL: an emerging tool for predicting severity of AKI is easily detected by a clinical assay" potx
... Devarajan P, Schlattmann P, Haase-Fielitz A: Accuracy of neutrophil gelatinase-associated lipocalin (NGAL) in diagnosis and prognosis in acute kidney injury: a systematic review and meta-analysis ... clinical settings [3] Most of the studies evaluating NGAL as a predictor of AKI used a research-based ELISA assay The availability of a standardized clinical platform for NGAL measurement would make ... a cohort analysis Crit Care 2006, 10:R73 Devarajan P: Neutrophil gelatinase-associated lipocalin an emerging troponin for kidney injury Nephrol Dial Transplant 2008, 23:3737-3743 Haase M, Bellomo...
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