... further examine the expression of IL-17A in actively inflamed joints and to elucidate the mechanism of IL-17A, alone and in combination with TNF-α and oncostatin M (OSM) in matrix turnover and cartilage ... 30 minutes and 3,3'-diaminobenzidine tetrahydrochloride for five minutes Nuclear counterstaining was performed using Mayer's haematoxylin, the sections were then dehydrated, and mounted in Dibutyl ... Cartilage was formalin-fixed and embedded (e) Proteoglycan staining was demonstrated by safranin O-fast green immunostaining In the IL-17A-positive group, 82% showed a decrease in IL17A levels after...
Ngày tải lên: 09/08/2014, 14:22
... characteristic geographical distribution They show predominance in Asian and Latin American countries, including Mexico [7-10], and rarely appear in Caucasian countries This gives them a distinctive racial ... such as perforins and granzymes present in NK cells and in cytotoxic T lymphocytes [1618] Even if the biological information on lymphomas is growing, the invasive capacity and cell destruction ... explored in head and neck carcinomas and non-Hodgkin's lymphomas and reactive lymphocytes and peritumoral stroma [19-22] In cancer, in spite of the classical proteolysis of the basal membrane and...
Ngày tải lên: 09/08/2014, 07:22
Báo cáo y học: " Blood product ratio in acute traumatic coagulopathy - effect on mortality in a Scandinavian level 1 trauma centre" pptx
... before and after study using historical controls Patients treated in 2001-3 were compared to patients treated in 2005-7 2004 was excluded, since HCR for massively bleeding patients was introduced ... after introduction of a massive transfusion (MT) protocol in group of MT patients [16] and in another study reported a reduction in multiple organ failure (MOF) and postinjury complications in patients ... studies report on findings from the combat scene and thereby a different kind of trauma patients with higher frequency of penetrating injuries than present in the current study Our findings however...
Ngày tải lên: 13/08/2014, 23:20
Tiết 1: Cổng trường mở ra
... 17: Văn : Sông núi nớc nam ( Nam quốc sơn hà) Phò giá kinh ( Tụng giá hoàn kinh s) a/ MụC TIÊU: Kiến thức: Giúp học sinh cảm nhận đợc tinh thần độc lập khí phách hào hùng, khát vọng lớn lao dân ... Thơng Trờng THCS Tân Lập Tìm bố cục đơn xin gia nhập đội VD: Đơn xin gia nhập đội thiếu niên tiền phong HCM: - Quốc hiệu - Tên đơn - Họ tên - Ngày, tháng, năm sinh - Học lớp trờng - Lí - Lời hứa ... mạch hợp lí Vì: thân ý 1-2-3 chủ yếu kể lại việc học tốt Cha phải kinh nghiệm học tốt - Cần nêu kinh nghiệm học tập, nhờ rút kinh nghiệm mà việc học tiến - Cuối cần nêu nguyện vọng đợc nghe ý...
Ngày tải lên: 27/06/2013, 11:45
Bài: Sử dụng chung 1 máy in
... máy in Share máy vi tính khác mạng tự động nhận thấy máy in Nếu không bạn phải chuyển qua cài đặt máy vi tính khác hệ thống mạng để dùng chung máy in Trong Printers and Faxes chọn Add a Printer ... the Add Printer Wizard chọn Next Trong Local or Network Printer Network Printer chọn A network printer or a printer attached to another computer nhấn Next để tiếp tục Trong specify a Printer chọn ... a printer nhấn Next Trong Browse for a Printer, ô Shared Printers bạn nhấp đúp chuột vào Microsoft Windows Network, nhấp đúp chuột (hoặc nhấn vào dấu +) vào WORKGROUP (lưu ý có số máy WORKGROUP,...
Ngày tải lên: 08/07/2013, 01:26
giao an toan tuan 1-18 IN ROI
... + Bảy trăm linh năm triệu hai trăm năm mươi nghìn ba trăm tám mươi Củng cố dặn dò: GV nhận xét tiết học Dặn HS nhà xem lại bài, ghi nhớ nội dung vừa học Dặn HS nhà làm tập IV RÚT KINH NGHIỆM TIẾT ... GV nhận xét tiết học Dặn HS nhà xem lại bài, ghi nhớ nội dung vừa học Dặn HS nhà làm tập IV RÚT KINH NGHIỆM TIẾT DẠY: Giáo án lớp Trường Tiểu Học Bùi Thò Xuân Cao Văn Hạnh KẾ HOẠCH BÀI DẠY Tuần ... thực phép tính cộng, trừ, nhân, chia theo cột dọc Cho HS làm vào Giáo án lớp HOẠT ĐỘNG CỦA HỌC SINH - HS ghi kết vào bảng Nghe - Đọc Làm Nghe - Đọc - Nhắc lại làm Nghe - Trường Tiểu Học Bùi...
Ngày tải lên: 17/08/2013, 13:10
Tiết 1- Cổng trường mở ra
... sinh lín lao èm cđa mĐ dµnh cho con? - Khãc nøc në - Lo sỵ qu»n qu¹i - Bá c¶ h¹nh cđa m×nh ®Ĩ ®ỉi cho khái ®au ®ín - ¨n xin, hi sinh tÝnh m¹ng ®Ĩ nu«i ? Tõ ®ã «ng ®· nh¾c nhë g×? -> Sù hi sinh ... chë, lµ chç dùa tinh thÇn, lµ ngn an cđa ? Tõ ®ã «ng ®· cã yªu cÇu g×? - Kh«ng ®ỵc t¸i ph¹m ? ¤ng yªu cÇu ph¶i nhËn lçi - Thµnh khÈn xin lçi mĐ, cÇu xin mĐ tha lçi nh thÕ nµo? (CÇu xin mĐ h«n con) ... tr¹ng - T×nh yªu th¬ng, sù hi sinh v« bê bÕn cđa ®au ®ín nh vËy? cha mĐ nhÊt lµ cđa mĐ ®èi víi nhng ®øa ®· phơ c«ng lao cha mĐ, cã nh÷ng th¸i ®é kh«ng ph¶i víi ngêi sinh m×nh ? Nh÷ng chi tiÕt nµo...
Ngày tải lên: 15/09/2013, 07:10
Học vần lớp 1- Vần in- un
... Thứ ngày tháng năm 2010 Học vần Bài 48: in -un in p in đèn pin un giun giun Thứ ngày tháng năm2010 Học vần Bài 48: in -un in un Pin giun Đèn pin nhà in xin lỗi Con giun mưa phùn vun xới Củng cố...
Ngày tải lên: 10/10/2013, 03:11
Tài liệu Chapter 1 - Living in a Network Centric World CCNA Exploration 4.0 pptx
... Website: www.bkacad.com Networking Career Opportunities • Information Technology and networking careers are growing and evolving as fast as the underlying technologies and services H c vi n m ng ... Online learning opportunities can decrease time-consuming and costly travel yet still ensure that all employees are adequately trained to perform their jobs in a safe and productive manner Online ... courseware and delivery offer many benefits to businesses such as: – Current and accurate training materials – Availability of training to a wide audience – Consistent quality of instruction...
Ngày tải lên: 12/12/2013, 14:15
Tài liệu The Insider’s Guide to PR: Chapter 1 WORKING IN A PR CONSULTANCY doc
... industry an excellent grounding in fundamental PR practices Graduate trainee programmes, in particular, are an excellent platform from which to gain varied experience with different sectors and ... is all invaluable experience in recognising where PR fits into the broader marketing picture • Derek Harris Senior Account Manager Republic PR and Business graduate • Social Life – Having explored ... both internal and external evaluation programmes to assess the success of a specific project or on-going PR programme Before a project commences, evaluation starts at the planning stage using...
Ngày tải lên: 13/12/2013, 04:15
Tài liệu Báo cáo khoa học: Lipopolysaccharide-evoked activation of p38 and JNK leads to an increase in ICAM-1 expression in Schwann cells of sciatic nerves ppt
... cells) and CD31 (a marker of endothelial cells) In previous studies, ICAM-1–integrin interactions mediated adhesion of leukocytes to the vascular endothelium, revealing a key role in migration ... SCs have been implicated in human in ammatory demyelinating neuropathies such as ´ Guillain–Barre syndrome and chronic in ammatory demyelinating polyneuropathy [31] In experimental autoimmune ... of SAPK ⁄ JNK in mediating LPS-induced ICAM-1 expression in SCs JNK phosphorylates c-Jun and ATF-2 and increases their ability to activate transcription, leading to c-jun induction and subsequent...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khoa học: Role of transcription factor activator protein 1 (AP1) in epidermal growth factor-mediated protection against apoptosis induced by a DNA-damaging agent doc
... and EGF receptor protein-tyrosine kinases in vivo and in vitro Cell 57, 1109–1122 18 Holgado-Madruga M, Emlet DR, Moscatello DK, Godwin AK & Wong AJ (1996) A Grb2-associated docking protein in ... members has been described as a primary event in determining the susceptibility to apoptosis through maintaining the integrity of the mitochondria and inhibiting activation of the caspase cascade [37] ... addition, several studies indicate that growth factors such as nerve growth factor, insulin-like growth factor, fibroblast growth factor, epidermal growth factor (EGF), and hepatocyte growth factor can...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: Association of feather colour with constitutively active melanocortin 1 receptors in chicken docx
... of [3H]cAMP and bovine adrenal binding protein and incubation for h at °C Standards containing nonlabeled cAMP were assayed in the same manner The incubates were then harvested by adding activated ... bovine serum (Biotech Line), 2.4 mM L-glutamine, 2.5 mgÆmL)1 G418, 2.5 lgÆmL)1 amphotericin, and 100 lgÆmL)1 kanamycin solution (all from Gibco BRL) until harvesting, after 48 h Binding assays Intact ... ERfayoumi resulted in competition curves for a-MSH and NDP-MSH using iodinated [125I]NDP-MSH as radioligand The binding curves are shown in Fig The IC50 for the MSH ligands are shown in Table Three...
Ngày tải lên: 21/02/2014, 00:20
mobile mini robots for engineering, Vol.6, No.1 Published in Australia© 2002 pdf
... (1997) Schilling, K., Telediagnosis and Teleinspection Potential of Actual Telematic Techniques In: Leeming, M.B and Topping, B.H.V (Eds), Innovation in Civil and Construction Engineering Edinburgh: ... demonstrations of a forklift handling device and optical line following system A rock and sand landscape similar to Mars, including facilities for a tether link to power and control rovers A rover ... to find the guidance line from any starting location Implementation of methods to follow the lines in a known environment towards the target, despite line crossings and a random starting point...
Ngày tải lên: 05/03/2014, 15:20
Báo cáo khoa học: High negative charge-to-size ratio in polyphosphates and heparin regulates factor VII-activating protease pdf
... heparin and N-acetyl heparin promote an increase in FSAP activity rather than inhibiting it Thus, polyanion binding to SERPINs, over and above their binding to FSAP, plays a decisive role in mediating ... rat mast cell granules effectively proteolyzes apolipoprotein AI-containing lipoproteins, so reducing the cholesterol efflux-inducing ability of serum and aortic intimal fluid J Clin Invest 97, 2174–2182 ... as a1-antitrypsin, a2-antiplasmin, antithrombin (AT) and C1 inhibitor [4,12–14], as well as plasminogen activator inhibitor (PAI-1) [15] and protease nexin [16] AT and a2-antiplasmin were shown...
Ngày tải lên: 07/03/2014, 02:20
Báo cáo Y học: Solution structure of the Alzheimer amyloid b-peptide (1–42) in an apolar microenvironment Similarity with a virus fusion domain potx
... The column was maintained at 45 °C and perfused at a flow rate of mLÆmin)1 with a mobile phase containing solvent A (5 mM ammonium acetate, pH in 5% acetonitrile), and a linear gradient from to ... time domain data were multiplied by shifted sine functions (COSY) or lorentz-to-gauss windows (NOESY, TOCSY) in the direct dimension, and by shifted sine or sine square functions in the indirect ... spectra) were integrated with NMRView and were converted into upper distance bounds with the routine CALIBA of the program package DYANA [29] After discarding redundant and duplicated constraints, the...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo khoa học: Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1⁄TSC2 in C2C12 myotubes pptx
... in regulating the rate of protein synthesis and cell hypertrophy in skeletal muscle [3–6] mTOR is a serine ⁄ threonine kinase of the phosphatidylinositol kinase-related kinase family and is highly ... phosphoinositide 3-kinase (PI3K) and its downstream effector Akt, triggering multiple downstream signaling events, including mTOR activation [8] Studies in both Drosophila and mammalian cells have indicated ... difference versus control group (P < 0.05) Phosphorylation of Akt and S6K1 was induced within 10 min, and was maintained for at least 60 Altered distributions of TSC1 and TSC2 proteins were also detected...
Ngày tải lên: 15/03/2014, 11:20
Báo cáo khoa học: Glycogen synthase kinase 3b and b-catenin pathway is involved in toll-like receptor 4-mediated NADPH oxidase 1 expression in macrophages ppt
... atherosclerosis Materials and methods Reagents Cell culture reagents, including fetal bovine serum, were obtained from Life Technologies (Grand Island, NY, USA) GSK3b, b-catenin and b-actin antibodies were ... for the indicated times and fractionated into cytosolic and nuclear extracts Western blot on both extracts was determined by using anti(b-catenin) serum b-Tubulin served as loading control and nuclear ... GSK3b-b-catenin is involved in Nox1 expression A β-catenin β-actin 15 30 45 60 LPS (min) B β-catenin β-actin 10 50 100 500 LPS (ng·mL–1) C β-catenin (short) β-catenin (long) β-tubulin 15 30 45 60...
Ngày tải lên: 22/03/2014, 21:21
MEMORANDUM D17-1-10: In Brief potx
... not exceeding 50 grams Greater than 50 grams but not exceeding 100 grams Greater than 100 grams but not exceeding 150 grams Greater than 150 grams but not exceeding 200 grams Memorandum D17-1-10 ... anti-dumping duty and/ or countervailing duty owing which results in a nil payment; – Goods are subject to a CITT finding and/ or a surtax order Anti-dumping duty and/ or countervailing duty, and/ or ... supporting invoice In the “No.” section of this field, show the customs business account number This number is a standard way of identifying importing and exporting businesses, and is used in the...
Ngày tải lên: 23/03/2014, 03:20