... neoepitopes – C1, 2C, C2C, CS846 and CPII The collagen degradation markers C1, 2C and C2C and the synthesis markers CS846 and CPII were measured by competitive immunoassay as per manufacturer's instructions ... MSD assay The assay standard range was 0.15 pg/ml to 10,000 pg/ml The lowest limit of detection was 0.4 pg/ml Quantification of cartilage neoepitopes – C1, 2C, C2C, CS846 and CPII The collagen degradation ... in the IL-17A-negative and positive patients There were no significant differences in the serum levels of C1, 2C, C2C and CPII pre/post therapy in either group However, CS846 a marker of proteoglycan...
Ngày tải lên: 09/08/2014, 14:22
... in head and neck carcinomas and non-Hodgkin's lymphomas and reactive lymphocytes and peritumoral stroma [19-22] In cancer, in spite of the classical proteolysis of the basal membrane and the ... between endothelial and neoplastic cells, and MMP-1 and MMP-11 Non-Hodgkin lymphomas are a large and heterogeneous group of tumors, which differ, in biological aggressiveness and clinical course ... endothelium and residual epithelial cells (surface and mucus gland ductal epithelium) For evaluations a double-headed microscope was used with a high resolution objective Figure ate and extensive...
Ngày tải lên: 09/08/2014, 07:22
Báo cáo y học: " Blood product ratio in acute traumatic coagulopathy - effect on mortality in a Scandinavian level 1 trauma centre" pptx
... period 2001-3 and 2005-7 for each period the plots show correlations between: a) age (years) and rbc 0-6 h (n), b) age (years) and ffp 0-6 h (n) and c) age (years) and plt 0-6 h (n) rho and p-values ... blood transfusion and positively with number of transfused RBC, FFP and PLT 0-6 h (both periods) and FFP:RBC, PLT:RBC and PLT:FFP ratios (only 2005-7) (data not shown) Dirks et al Scandinavian Journal ... delivery, type and amount of blood products (RBC, FFP and PLT) in the first hours, 6-12, 12-24 hours and total amount during hospital stay, admission hematology and coagulation, LOS and mortality...
Ngày tải lên: 13/08/2014, 23:20
Bài: Sử dụng chung 1 máy in
... bạn phải chuyển qua cài đặt máy vi tính khác hệ thống mạng để dùng chung máy in Trong Printers and Faxes chọn Add a Printer Trong Welcome to the Add Printer Wizard chọn Next Trong Local or Network ... nhấn Finish để hoàn tất Sau máy in cài đặt xong có biểu tượng (Icon) tên máy in mạng nằm Printers and Faxes Từ máy mạng in tài liệu trực tiếp từ máy ...
Ngày tải lên: 08/07/2013, 01:26
Tài liệu Chapter 1 - Living in a Network Centric World CCNA Exploration 4.0 pptx
... opportunities and challenges posed by converged networks Describe the characteristics of network architectures: fault tolerance, scalability, quality of service and security Install and use IRC clients and ... businesses, to address emergencies, to inform individuals, and to support education, science, and government Play video to watch how the Internet, and its underlying technology, brings opportunities ... We Learn • • • • Communication, collaboration, and engagement are fundamental building blocks of education Robust and reliable networks support and enrich student learning experiences Courses...
Ngày tải lên: 12/12/2013, 14:15
Tài liệu The Insider’s Guide to PR: Chapter 1 WORKING IN A PR CONSULTANCY doc
... which to gain varied experience with different sectors and clients The very nature of in-house PR, on the other hand, makes it sector specific and offers little room for manoeuvre For this reason, ... young people and consequently foster a fun and stimulating environment in which to work Some of the larger consultancies have their own bars or break-out rooms, or at least beer fridges, and actively ... marketing disciplines, need to prove the value of their work, and in so doing, justify their fees! They this through both internal and external evaluation programmes to assess the success of a...
Ngày tải lên: 13/12/2013, 04:15
Tài liệu Báo cáo khoa học: Lipopolysaccharide-evoked activation of p38 and JNK leads to an increase in ICAM-1 expression in Schwann cells of sciatic nerves ppt
... cytokines and chemokines, to express major histocompatibility complex (MHC) class II molecules and adhesion molecules, and to serve as antigen-presenting cells [18–20] These chemokines and inflammatory ... for ICAM-1 and NF-200 Scale bar = 20 lm I blot and ELISA revealed that induction of ICAM-1 was substantially inhibited by U0126 (20 lm), and completely abolished by SB202190 (10 lm) and SP600125 ... antigen-presenting cells and activate T cells in vitro in an antigen-specific and MHC-restricted manner [32], especially in the presence of cytokines Natural ligands of ICAM- 1and LFA-1 are expressed...
Ngày tải lên: 18/02/2014, 18:20
Tài liệu Báo cáo khoa học: Role of transcription factor activator protein 1 (AP1) in epidermal growth factor-mediated protection against apoptosis induced by a DNA-damaging agent doc
... 29) or with the empty bcl-XL expression vector (clone pc10) and isolated each clone When clone no 29 and clone pc10 cells were exposed to ADR and assayed for DNA ladder formation, clone no 29 cells ... with EGF and ADR as described in (A), harvested at the indicated times after the addition of ADR, and used for immunoblot analysis of pro-caspase and caspase (C) Cells were treated with EGF and ADR ... levels of key antiapoptotic (i.e Bcl-2 and Bcl-XL) and proapoptotic (i.e Bad and Bax) proteins Cells were incubated in the presence of EGF for several periods, and cell lysates were prepared from...
Ngày tải lên: 19/02/2014, 06:20
Tài liệu Báo cáo khoa học: Association of feather colour with constitutively active melanocortin 1 receptors in chicken docx
... corresponding position in the human MC1 and MC4 receptors by site-directed mutagenesis and generated clones termed hMC1-E94K and hMC4-E100K The clones were expressed and assayed pharmacologically in ... skin; it is white or cream for the ewh and ey males and grey for the e+ and eb In melanic alleles (E, ER, and ERfayoumi), adult males are black in all areas and the flight feathers are also black ... the human wild-type MC1 (u), human MC1 (E94K) (m), and wild-type MC4 (j), human MC4 (E100K) (r) receptors Data points represent means of duplicates and error bars indicate standard error of the...
Ngày tải lên: 21/02/2014, 00:20
mobile mini robots for engineering, Vol.6, No.1 Published in Australia© 2002 pdf
... demonstrations of a forklift handling device and optical line following system A rock and sand landscape similar to Mars, including facilities for a tether link to power and control rovers A rover ... WWW-server that interfaces with clients and handles over the Internet the transfer of sensor data from the operator workplace and commands to the rover The WWW-server and the operator workplace exchange ... Design and programming of a first simple control Calibration of sensors and actuators Conception of performance tests and their documentation Adaptation and fine-tuning of the sensor and control...
Ngày tải lên: 05/03/2014, 15:20
Báo cáo khoa học: High negative charge-to-size ratio in polyphosphates and heparin regulates factor VII-activating protease pdf
... a1-antitrypsin, a2-antiplasmin, antithrombin (AT) and C1 inhibitor [4,12–14], as well as plasminogen activator inhibitor (PAI-1) [15] and protease nexin [16] AT and a2-antiplasmin were shown to be efficient ... in the BSA band (Fig 1A) Concentrationdependent analysis indicated that the EC50 was 95 ± nm for the shift with unfractionated heparin and 28 ± nm for PolyP65 (Fig 1B and Figs S1 and S2) To examine ... heparin and PolyP65 (Fig S5) Heparan sulfate was a co-factor at high concentrations (Fig 3A, lower panel), and dermatan sulfate and polysialic acid C Fig Inhibition of FSAP by PAI-1 and AT; co-factor...
Ngày tải lên: 07/03/2014, 02:20
Báo cáo Y học: Solution structure of the Alzheimer amyloid b-peptide (1–42) in an apolar microenvironment Similarity with a virus fusion domain potx
... the transmembrane region of APP, and has the typical amino acid composition of transmembrane helices, i.e small (Gly and Ala) and hydrophobic (Ile, Leu, Met and Val) residues [36] The only charged ... methods using standard solid-phase synthesis techniques [17] with a Milligen 9050 synthesizer Protected amino acids and chemicals were purchased from Bachem, Novabiochem or Fluka (Switzerland) The resin ... easily soluble in aqueous solutions and in organic solvents; the trifluoroacetic acid treated Ab exhibits the properties of monomeric, random coil structures and lacks preaggregated material [20]...
Ngày tải lên: 08/03/2014, 09:20
Báo cáo khoa học: Insulin like growth factor-1-induced phosphorylation and altered distribution of tuberous sclerosis complex (TSC)1⁄TSC2 in C2C12 myotubes pptx
... the function of the TSC1 ⁄ TSC2 protein complex in response to IGF-1 treatment To investigate the subcellular localization profile of TSC1 and TSC2 in C 2C1 2 myotubes, the C 2C1 2 lysates were fractionated ... fractionation The C 2C1 2 myoblasts were plated in a cell culture dish (diameter 60 mm) and then differentiated to myotubes for days C 2C1 2 myotubes were washed twice with NaCl ⁄ Pi and then scraped ... mTOR activity by modulating the interaction between TSC1 ⁄ TSC2 protein complex and Rheb Materials and methods Materials C 2C1 2 mouse myoblasts and human embryonic kidney 293 cells were purchased...
Ngày tải lên: 15/03/2014, 11:20
Báo cáo khoa học: Glycogen synthase kinase 3b and b-catenin pathway is involved in toll-like receptor 4-mediated NADPH oxidase 1 expression in macrophages ppt
... is variable and complicated, and Nox and its function have become current issues Seven types of Nox have been found The most studied is Nox2; however, other types, especially Nox1 and Nox4, are ... p22phox and the Nox1 regulators NoxA1 and NoxO1 [5], but an increase in Nox1 gene expression is also essential Angiotensin II and platelet-derived growth factor lead to increased Nox1 mRNA levels and ... were fixed and stained with anti-(b-catenin) serum and DAPI and observed using fluorescent microscopy (C) Nox1 mRNA was analyzed by RT-PCR (D–F) Raw264.7 cells were transfected with a pEGFP -C1 vector...
Ngày tải lên: 22/03/2014, 21:21
MEMORANDUM D17-1-10: In Brief potx
... provisional, anti-dumping and/ or countervailing duty refer to the Memoranda D14 and D15 series Show the amount in dollars and cents separated by a decimal point Note: These amounts and/ or duties form ... according to Memorandum D17-1-11, Private Printing Policy and Procedures Importers/brokers must apply coloured wrappers to B3 forms as follows: Type AB and AD (LVS threshold or more) AB and AD (less ... length and contains the following: (a) the first five digits represent the account security number of the importer/broker who will present the accounting document and/ or pay the duties and taxes; and...
Ngày tải lên: 23/03/2014, 03:20