... S, Akabayashi A, Kai I, Ohi G, Naka K: Correlation between history of contact with people living with HIV/AIDS (PWAs) and tolerant attitudes toward HIV/AIDS and PWAs in rural Thailand International ... first-line antiretroviral therapy in South Africa Antivir Ther 2008, 13(7):937-43 Colebunders R, Kamya MR, Laurence J, Kambugu A, Byakwaga H, Mwebaze PS, Muganga AM, Katwere M, Katabira E: First-line antiretroviral ... clinical practice: a systematic review Tropical Medicine and International Health 2011 Jaffar S, Amuron B, Foster S, et al: Rates of virological failure in patients treated in a home-based versus a...
... size, it has a decided advantage in ease of absorption “This breed can be traced back for 2,000 years and was always famous for dairy purposes In temperament, these animals are quiet and docile, ... standard against any agent or condition that may attempt to alter it And when temporarily or accidentally that standard may be departed from, we see immediately an attempt to repair the damage ... next day start with the milk as early as usual, again stop at noon, and eat a somewhat heartier meal in the evening, if the appetite calls for it Another meal that may be taken the first day is...
... obtained was used asa template for real-time quantitative polymerase chain reaction, which was performed with the LC FastStart DNA Master SYBR GreenI® (Roche Diagnostics, Mannheim, Germany) in a LightCycler® ... receptors and are activated by lipopolysaccharide J Exp Med 2003, 197:403-411 Nagai Y, Akashi S, Nagafuku M, Ogata M, Iwakura Y, Akira S, Kitamura T, Kosugi A, Kimoto M, Miyake K: Essential role ... Freeman GJ: The B7-CD28 superfamily Nat Rev Immunol 2002, 2:116-126 20 Matsuyama T, Yamada A, Kay J, Yamada KM, Akiyama SK, Schlossman SF, Morimoto C: Activation of CD4 cells by fibronectin and anti-CD3...
... self-tolerance; deficit of a T cell subset asa possible cause of autoimmune disease J Exp Med 1985, 161:72-87 Kuniyasu Y, Takahashi T, Itoh M, Shimizu J, Toda G, Sakaguchi S: Naturally anergic and ... Sakaguchi S, Fukuma K, Kuribayashi K, Masuda T: Organ-specific autoimmune diseases induced in mice by elimination of T cell subset I Evidence for the active participation of T cells in natural ... Arthritis Research Vol No Horwitz et al can serve asa therapy for autoimmune diseases such as systemic lupus erythematosus (SLE) This T-cell-based therapy could also be used to prevent graft...
... other arbitrary measures for disease classification Adopting a systems biology approach, whereby adisease defining molecular fingerprint is analysed, would increase the accuracy of disease diagnosis, ... vision, as others have also adopted this strategy asa way forward in molecular analysis Alagaratnam et al are utilising Bayesian approaches to pursue muscular dystrophy diagnosis [223] Similarly, ... Myeloperoxidase Neutrophil elastase TIMP-1 TNF-alpha Cystic fibrosis, general lung injury, lung cancer Lung cancer, asthma Asthma, idiopathic pulmonary fibrosis, lung cancer, heart disease Pulmonary sarcoidosis,...
... rather sweeping assertions of ‘‘brain abnormalities.’’ Sheehan (1986) advocates a broadly similar approach Although in his book The anxiety disease social phobia is broached tangentially Àas ... contentious and broader in scope than the similarly undefined term disease. ) The third strategy, which so far as I am aware has never yet been adopted, at least for a psychiatric classification, is ... distress and maladjustment is, according to him, a metaphoric one, arrived at by analogy The reasoning is as follows: since individuals with a bodily (i.e material) disease suffer and may have trouble...
... comprehensive approach aimed at making the healthy choices available, affordable and attractive involves taking account of mainstreaming nutrition and physical activity into all relevant policies at local, ... cardiovascular disease by 25%, while eating fish once or twice a week will reduce this risk by 25% In the Netherlands, every year, 38,000 cases of cardiovascular disease among adults aged 20 and ... weight management aspects, physical exercise has also independent positive effects on the prevention of diseases such as cardiovascular disease, type II diabetes, osteoporosis and depression, and...
... clinically important Fabry disease- associated a- galactosidase A variants (causing another lysosomal storage disease) were shown to be folding and trafficking mutants [16] before this was explored as ... ameliorate Gaucher disease 19 Fan JQ, Ishii S, Asano N & Suzuki Y (1999) Accelerated transport and maturation of lysosomal alpha-galactosidase A in Fabry lymphoblasts by an enzyme inhibitor Nat Med ... Therapeutics is currently in Phase II clinical trials for Fabry disease [18,19] A thorough review of a- galactosidase A pharmacologic chaperones for Fabry disease is provided in an accompanying...
... primarily: » heart disease and stroke (cardiovascular diseases); » cancer; » asthma and chronic obstructive pulmonary disease (chronic respiratory diseases); » diabetes Other chronic diseases are ... CHRONIC DISEASES AFFECT PRIMARILY MEN Certain chronic diseases, especially heart disease, are often viewed as primarily affecting men The truth is that chronic diseases, including heart disease, affect ... and acted on urgently Chapter One Chronic diseases: causes and health impacts WHAT ARE CHRONIC DISEASES? The main chronic diseases discussed in this report are: cardiovascular diseases, mainly...
... estado de São Paulo, Brasil: estudio poblacional Palabras clave 27 Organização Pan-Americana da Saúde Saúde nas Américas: 2007 Washington, D.C.: OPAS; 2007 (Scientific Publication No 662) 28 Wang ... significativamente la HRQOL en todas las áreas Las escalas más afectadas por las enfermedades fueron dolor físico, salud general y vitalidad Conclusiones Se encontró una alta prevalencia de enfermedades ... enfermedades crónicas estudiadas influyó significativamente en la puntuación de casi todas las escalas de la SF36® La HRQOL alcanzó valores inferiores cuando la persona ten a depresión/ansiedad,...
... hyperphosphorylation occurs because of an imbalance in the activity of tau kinases and phosphatases [3] One particular tau kinase pertinent to metal dyshomeostasis in AD is glycogen synthase kinase-3 ... Modulation of metal availability for treating AD P J Crouch et al research attention as potential therapeutic targets Plaques and NFTs, however, cannot be regarded as ‘upstream’ causative factors ... metal dyshomeostasis in all aspects is clear In the AD affected brain, metal dyshomeostasis is evident in the form of a substantial increase in the levels of extracellular metals and a decrease...
... assistance with this study This work was supported by a grant from the Marian Chace Foundation to Madeleine Hackney and a grant from the American Parkinson Disease Association to Gammon Earhart ... Scale (Lawton 1975) Balance was evaluated using the Functional Reach (Duncan et al 1990) and One Leg Stance Test (Vellas et al 1997) Walking velocity was assessed by tracking a reflective marker ... Hackney et al Adherence to an exercise program may be more likely if it is novel and enjoyable A study of those at risk of heart failure found that the waltz was just as good as traditional aerobic...
... education and disease and case management (for heart disease and stroke, diabetes, prenatal care, immunizations, breast and cervical cancer, diabetes, and asthma) but also the promotion of change ... in its heart disease and stroke prevention efforts Manual de Consulta para los Trabajadores de salud Comunitaria: Una herramienta para la prevención de car diopat as y derrames cerebrales (Sourcebook ... the burden of diabetes is disproportionately borne by American Indians and Alaska Natives, African Americans, Hispanic or Latino Americans, and Asians/Pacific Islanders The devel opment of diabetes...
... type diabetes subjects Immunogenetics 2010, 62:101-107 36 Kawasaki E, Awata T, Ikegami H, Kobayashi T, Maruyama T, Nakanishi K, Shimada A, Uga M, Kurihara S, Kawabata Y, et al: Genetic association ... Cobbold S, Alyanakian MA, Gouarin C, Barriot S, Garcia C, Waldmann H, Bach JF, Chatenoud L: Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic ... 48:6-11 19 Bernasconi A, Marino R, Ribas A, Rossi J, Ciaccio M, Oleastro M, Ornani A, Paz R, Rivarola MA, Zelazko M, Belgorosky A: Characterization of immunodeficiency in a patient with growth hormone...
... chronic diseases diabetes, COPD, asthma, arthritis, and heart failure We synthesized the data in a narrative way and used absolute numbers and proportions to summarize the data quantitatively ... chronic diseases a substantial number of self-efficacy instruments are available that cover disease- and task-specific aspects of self-efficacy For diabetes, substantially more self-efficacy instruments ... diabetes, chronic obstructive pulmonary disease (COPD), asthma, arthritis, and heart failure They all require complex activities like self-monitoring, an adequate adaptation of medication, and...
... study was smaller than we had anticipated We specifically expected that the OR for the association between having achronic condition and physical activity would have been larger Non-response bias ... Blumenthal JA, Babyak MA, Moore KA, Craighead WE, Herman S, Khatri P, Waugh R, Napolitano MA, Forman LM, Appelbaum M, Doraiswamy PM, Krishnan KR: Effects of exercise training on older patients ... mentioned above As shown in Figure 2, the HUI3 score was regressed on the chronic condition variable, and physical activity was specified asa mediator of this relationship The Pratt-Index (d) [25] was...
... Shimohama S, Tanino H, Kawakami N, Okamura N, Kodama H, Yamaguchi T, Hayakawa T, Nunomura A, Chiba S, Perry G, Smith MA, Fujimoto S: Activation of NADPH oxidase in Alzheimer's disease brains Biochem ... however, exactly how fAβ activates the astrocytic NADPH oxidase remains unclear [29,70] Abramov and colleagues have examined a potential role for astrocytic NADPH oxidase-derived ROS in fAβdependent ... Rho-family of small monomeric GTPases Like all Ras-superfamily members, Rac1 acts asa molecular switch cycling between an inactive guanosine diphosphate (GDP)-bound state and an active guanosine...
... chronic diseases diabetes, COPD, asthma, arthritis, and heart failure We synthesized the data in a narrative way and used absolute numbers and proportions to summarize the data quantitatively ... chronic diseases a substantial number of self-efficacy instruments are available that cover disease- and task-specific aspects of self-efficacy For diabetes, substantially more self-efficacy instruments ... diabetes, chronic obstructive pulmonary disease (COPD), asthma, arthritis, and heart failure They all require complex activities like self-monitoring, an adequate adaptation of medication, and...
... the US National Institutes of Health is in the planning stage 132 Although autoantibodies in autoimmune cytopenias and some other diseases, such as pemphigus and myasthenia gravis, have a direct ... in autoimmunity are available from patients with RA Initially, Edwards and Cambridge reported on five patients with refractory RA, all of whom had major improvement in disease activity and achieved ... joint-specific autoimmune disease Nat Immunol 2002, 3:360-365 Felson DT, LaValley MP, Baldassare AR, Block JA, Caldwell JR, Cannon GW, Deal C, Evans S, Fleischmann R, Gendreau RM, Available online http://arthritis-research.com/content/5/3/131...