bending moments reactions and thrust due to partial distributed load q tables a 29 a 30
Báo cáo y học: "Misdiagnosis and undiagnosis due to pattern similarity in Chinese medicine: a stochastic simulation study using pattern differentiation algorithm" pdf
... searched with a combinatorial procedure for quoted terms Sequentially, a list of candidate patterns was generated with patterns that explain at least one manifestation collected at the exam Patterns ... (simulation of manifestation profiles; cutoffestimation for N %; pattern identification with F% and N %-cutoff of simulated cases; and statistical analysis) Additionally, MPSA and PDA are composed ... Four Examinations and dual pattern similarity A cross-table was built by simultaneous classification of dual patterns into the categories of similarity S and according to the cumulative combinations...
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The NCI Strategic Plan for Leading the Nation To Eliminate the Suffering and Death Due to Cancer pdf
... biomarkers (also called tumor markers) include CA 125 (ovarian cancer), CA 15-3 (breast cancer), CEA (ovarian, lung, breast, pan creas, and gastrointestinal tract cancers), and PSA (prostate cancer) ... scientific advances > Coordinate and optimize patient-information and other data sharing by creating a comprehensive database of clinical trials and results > Create an integrated infrastructure to accelerate ... organizations to address differences in cancer occurrence and its consequences among all populations > Facilitate study design standardization to allow data compilation, analysis, and sharing across...
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Health Education to Villages: An integrated approach to reduce childhood mortality and morbidity due to diarrhoea and dehydration; Maharashtra, India 2005 – 2010 pptx
... Villages: an integrated approach to reduce childhood mortality and morbidity due to diarrhoea and dehydration; Maharashtra, India 2005 – 2010 Region and Country: Maharashtra, India Name of Local Partners: ... unnecessary and avoidable death is a great tragedy We wish to remember, finally, that health education is at its core an attempt to value these lives, and that a new order of health can be achieved to ... • Mass media 70% of all women in Maharashtra are regularly exposed to some form of mass media, and growing numbers of villagers are gaining access to television and radio If all the available...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 1) pptx
... complement activation, with bouts of production of membrane attack complex capable of severely damaging normal cells General Clinical and Laboratory Features The clinical presentation of a patient ... a patient with mild hereditary spherocytosis or with cold agglutinin disease may be diagnosed after years This is due in large measure to the remarkable ability of the body to adapt to anemia ... with anemia is greatly influenced by whether the onset is abrupt or gradual, and HA is no exception A patient with autoimmune hemolytic anemia or with favism may be a medical emergency, whereas a...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 2) docx
... hemolysis regularly produces an increased unconjugated bilirubin, increased lactate dehydrogenase (LDH), increased aspartate transaminase, and reduced haptoglobin Urobilinogen will be increased in both ... cytoplasm (to a final level of 340 g/L, i.e., about mM) goes hand in hand with the gradual loss of cellular organelles and of biosynthetic abilities In the end the erythroid cell undergoes a ... both urine and stool If hemolysis is mainly intravascular, the telltale sign is hemoglobinuria, often associated with hemosiderinuria and an increase in serum hemoglobin; in contrast, the bilirubin...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 3) pptx
... cirrhosis, and to the heart muscle, eventually causing heart failure The increased activity of the bone marrow also entails an increased requirement for erythropoietic factors, particularly folic acid ... especially if the patient needs frequent blood transfusions Chronic iron overload will cause secondary hemochromatosis; this will cause damage, particularly to the liver, eventually leading to cirrhosis, ... (compared to the normal value of about 120 days) is a red cell survival study, which can be carried out by labeling the red cells with 51 Cr and measuring residual radioactivity over several days or...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 5) ppt
... extracellular domains of many of these proteins are heavily glycosylated, and they carry antigenic determinants that correspond to blood groups Underneath the membrane, and tangential to it, is a ... changes that alter the normal biconcave disc shape Thus, the majority of the diseases in this group have been known for over a century as hereditary spherocytosis (HS) and hereditary elliptocytosis ... Minkowksy and Chauffard, who at the end of the 19th century reported families in whom HS was inherited as an autosomal dominant condition From this seminal work, HS came to be defined as an inherited...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 6) doc
... SLC 4A 1 7q2 1 Band HS (anion (dominant) channel) Mutations of this gene may account for ~25% of HS Southea st Polymorp Asian hic mutation ovalocytosis (deletion of (dominant) amino acids); clinically ... (Inheritance) SPTA1 1q2 2 -q2 3 αSpectrin HS Rare (recessive) HE (dominant) Mutations of this gene account for about 65% of More forms HE severe may be due to coexistence of an otherwise silent mutant allele ... 1 5q1 5 -q2 1 Band 4.2 HS (recessive) Mutations of this gene account for about 3% of HS RHAG 6p21.1-p11 Rhesu Chronic Very rare; s antigen nonspherocytic associated with hemolytic total loss of all...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 7) docx
... referred to as Southeast Asian ovalocytosis, has a frequency of up to 7% in certain populations, presumably as a result of malaria selection Stomatocytosis This rare condition with autosomal dominant ... (1) The patient may have a de novo mutation, i.e., a mutation that has taken place in a germ cell of one of his parents or early after zygote formation; and (2) the patient may have a recessive ... evidence-based) are as follows Avoid splenectomy in mild cases Delay splenectomy until at least years of age, after the risk of severe sepsis has peaked imperative, Antipneumococcal whereas vaccination...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 8) pdf
... anemia may get worse In part the delay in diagnosis is due to the fact that the anemia is remarkably welltolerated because the metabolic block at the last step in glycolysis causes an increase ... neonatal jaundice; the jaundice persists and is usually associated with a very high reticulocytosis The anemia is of variable severity; sometimes it is so severe as to require regular blood transfusions; ... a nearly compensated hemolytic disorder As a result, the diagnosis may be delayed, and in some cases it is made in young adults—for instance, in a woman during her first pregnancy, when the anemia...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 9) ppsx
... deficiency is a prime example of an HA due to interaction between an intracorpuscular and an extracorpuscular cause, because in the majority of cases hemolysis is triggered by an exogenous agent Although ... severe neonatal jaundice, which may require exchange transfusion; if the anemia is less severe, it may present later in life or may even remain asymptomatic and be detected incidentally when a blood ... (heterozygous) As a result of the phenomenon of X-chromosome inactivation, heterozygous females are genetic mosaics, with a highly variable ratio of G6PD-normal to G6PDdeficient cells and an equally variable...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 10) pps
... drugs (Table 101-5) Typically, a hemolytic attack starts with malaise, weakness, and abdominal or lumbar pain After an interval of several hours to 2–3 days, the patient develops jaundice and often ... especially in association with prematurity, infection, and/ or environmental factors (such as naphthalenecamphor balls used in babies' bedding and clothing) In these cases, if inadequately managed, ... widespread variants are G6PD Mediterranean on the shores of the Mediterranean Sea, in the Middle East, and in India; G6PD A in Africa and in Southern Europe; G6PD Vianchan and G6PD Mahidol in...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 11) doc
... Others Sulfadim idine Sulfadiazi ne Dapsone Antibacterial/anti Cotrimoxazole biotics Ciproflo xacin Nalidixic acid Chloramp henicol Norfloxa cin pAminosalicylic acid Nitrofurantoin Niridazole Antipyretic/analg ... Microangio pathic Acute or chronic Red cell Red cell Different fragmentation morphology on causes ranging blood smear from endothelial damage to hemangioma to leaky prosthetic heart valve March Abrupt ... Mismatche d Abrupt blood Nearly always transfusion Repeat ABO cross match incompatibility Paroxysmal Chronic Comple nocturnal with acute ment hemoglobinuria exacerbations mediated (PNH) Flow Exacerba...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 12) doc
... Peripheral blood smear from a 5-year-old G6PD-deficient boy with acute favism A very small minority of subjects with G6PD deficiency have CNSHA of variable severity The patient is always a male, usually ... with a history of NNJ, who may present with anemia or unexplained jaundice, or because of gallstones later in life The spleen may be enlarged The severity of anemia ranges from borderline to transfusion-dependent ... vulnerable to acute oxidative damage, and therefore the same agents (see Table 101-5) that can cause acute HA in people with the ordinary type of G6PD deficiency will cause severe exacerbations in people...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 13) pptx
... complement regulatory proteins: membrane cofactor protein, factor H, and factor I It is thought that when complement is activated through the alternative pathway following damage to endothelial cells ... Shiga toxin–related HUS can be regarded as a phenocopy of familial HUS Acquired Hemolytic Anemia Mechanical Destruction of Red Cells Although red cells are characterized by the remarkable deformability ... defined as a microangiopathic hemolytic anemia with fragmented erythrocytes in the peripheral blood smear, thrombocytopenia (usually mild), and acute renal failure An infection is usually the...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 14) pps
... point of view, an important feature is that AIHA can appear to be isolated, or it can develop as part of a more general autoimmune disease, particularly systemic lupus erythematosus (SLE), of ... lab is advisable; the term Coombs-negative AIHA is a last resort In some cases the autoantibody has a defined identity: it may be specific for a Rhesus system antigen (often anti-e) In many cases ... some cases the nature of the antibody is such (usually an IgM antibody) that the antigen-antibody complex on the surface of red cells is able to activate complement (C) As a result, a large amount...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 15) potx
... Cold Agglutinin Disease (CAD) This designation is used for a form of chronic AIHA that usually affects the elderly and has special clinical and pathologic features First, the term cold refers to ... forms of CAD, avoidance of exposure to cold may be all that is needed to enable the patient to live with a reasonably comfortable quality of life, but in more severe forms the management of CAD is ... unique clinical condition; however, when not all of these three features are manifest on presentation, the diagnosis is often delayed, although it can be always made by appropriate laboratory...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 16) ppt
... secondary to severe neutropenia and hemorrhage secondary to severe thrombocytopenia PNH may evolve into aplastic anemia (AA), and PNH may manifest itself in patients who previously had AA Rarely ... Hemoglobinuria may be overt in a random urine sample; if it is not, it may be helpful to obtain serial urine samples, since hemoglobinuria can vary dramatically from day to day, and even from hour to hour ... cell (i.e., they are somatic mutations) As a result, the patient's marrow is a mosaic of mutant and nonmutant cells, and the peripheral blood always contains both PNH cells and normal (non-PNH) cells...
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Chapter 101. Hemolytic Anemias and Anemia Due to Acute Blood Loss (Part 17) potx
... Eculizumab administered intravenously at q2 wk intervals also ameliorated the anemia in most patients and dramatically improved their quality of life Figure 101-9 Therapeutic efficacy of an anti-C5 antibody ... (ALG or ATG) and cyclosporine A may be indicated Although no formal trial has ever been conducted, this approach has helped particularly to relieve severe thrombocytopenia and/ or neutropenia ... necessary Folic acid supplements (at least mg/d) are mandatory; the serum iron should be checked periodically and iron supplements administered as appropriate Long-term glucocorticoids are not...
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Module V Viruses and Worms.Introduction to VirusComputer viruses are perceived as a threat to potx
... which include a day, time, or a particular event • Ex: TSR viruses which get loaded into memory and infect at later stages Attack Phase: • Some viruses have trigger events to activate and corrupt ... Create Computer Viruses Virus writers can have various reasons for creating and g spreading malware Viruses have been written as: • • • • • • • • • Research projects Pranks Vandalism To attack ... • Magnetic fields due to floppy disk, monitor, and telephone can damage stored data Software Threats Software Problems: • In multitasking environment, software conflicts may occur due to sharing...
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- how does the law of conservation of matter and energy apply to nuclear reactions
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- compression axial compression due to bending moment and shear in the presence of hoop compression
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- are differences in conditions and outcomes due to nesting in hospitals or to qics
- beam reactions bending moments and deflections
- ``degraded modes´´ due to partial equipment failure
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