apc β catenin deregulation in desmoid tumors important implications for diagnosis prognosis and therapy
báo cáo hóa học:" Quality of data collection in a large HIV observational clinic database in sub-Saharan Africa: implications for clinical research and audit of care" docx
... (age and CD4+ cell count) Table Number and incidence rates of opportunistic infections in the initial 24 months after ART initiation, and percent underreporting of OI events in routine clinic ... discontinuation and modification This gives a total error rate (comprising missing and incorrect items) of 67% for OIs, 52% for ART-related toxicities, and 83% and 58% for ART discontinuation ... patients in the routine clinic database who also initiated ART between April 2004 and April 2005, and who were not enrolled into the research cohort; and the 6421 patients in the routine clinic database...
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Báo cáo Y học: Regulation of a1,3galactosyltransferase expression in pig endothelial cells Implications for xenotransplantation doc
... TATA-binding-protein-associated factors and initiator-binding proteins Mol Cell Biol 17, 2973–2984 32 Weis, L & Reinberg, D (1992) Transcription by RNA polymerase II: initiator-directed formation ... binding sites detected using TRANSFAC are indicated above the sequence and are represented by horizontal lines sites that could be important for promoter activity in pig cells, such as GATA- and ... exons and (PCR product obtained with primers p17 and p18, Table 1, subcloned in pGEM-T-easy) or pig E-selectin cDNA, corresponding to transcripts 5¢-A and -C, 5¢-B and -E, a1,3GalT coding sequence...
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Báo cáo khoa học: High and complementary expression patterns of alcohol and aldehyde dehydrogenases in the gastrointestinal tract Implications for Parkinson’s disease docx
... studies including investigations in human tissues, and that this has implications for how to interpret the role of the studied enzymes in health and disease Results The distribution and relative intensity ... Adh4 is found in the epithelial lining of upper GI tract including the tongue, esophagus and stomach, but not in the small and large intestines In the rat, Aldh1 is present higher up in the GI tract ... the villi and in the intestinal glands, while submucosal glands were empty In jejunum and ileum, Adh1 1214 mRNA showed a similar expression pattern as described for duodenum In colon and rectum,...
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Innovations in Credit Risk Transfer: Implications for Financial Stability docx
... Corporate Investment and Financing Policies The Journal of Finance 48, 1629–1658 Froot, K and J Stein (1998) Risk Management; Capital Budgeting and Capital Structure Policy for Financial Institutions: ... relief against selling costs For example, in the case of selling costs arising from information about borrower quality that is held privately by banks, Leland and Pyle [1977] use a signalling equilibrium ... reduction in the costs of raising external capital for loan intermediation As suggested by Froot, Scharfstein, and Stein [1993] and Froot and Stein [1998], we expect an equilibrium in which a...
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Poultry of the Middle in the U.S.: ‘Implications for Sustainable Producers & Scaling Up’ pdf
... basic research using the Internet and interviewing key informants Multiple key informants were identified through contacts in the industry and on the Internet Informants were interviewed by telephone ... by processing technology Stunning, killing and plucking Birds are stunned to render them unconscious before killing in most processing plants While required by law in Europe and used in slaughterhouses ... producer or of the grocery chain where sold Changes in dietary preferences have had a major influence in creating increased demand for poultry in the U.S in the past 40 years In 1960, poultry was 16%...
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Competency-based education in the health professions: Implications for improving global health doc
... usage, “standard” refers to learner performance and contrasts with the frequent use of “standard” in reference to a “standard curriculum” and even a “standardized examination.” Defining the curriculum ... considered In Australia, for example, the provincial government struggled to change the health outcomes for key chronic diseases for remote, rural and Indigenous populations However, using a training ... and reflect national, professional and client stakeholders, including learners Such competency definitions are intended, among other things, to communicate priorities in a memorable and meaningful...
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Báo cáo hóa học: " miR-17-92 expression in differentiated T cells - implications for cancer immunotherapy" docx
... FACs analysis, cells were incubated with mAb at 4°C for 30 min, washed twice in staining buffer, and fixed in 500 μl of 2% paraformaldehyde in PBS Cells were stored in the dark at 4°C until analysis ... functions Our findings indicate that the tumor-bearing host down-regulates miR-17-92 in T cells (Fig and 4) Interestingly, not only are STAT6-/- T cells resistant to tumor-induced inhibition of ... silencing in non-human primates Nature 2008, 452:896-899 Cheng AM, Byrom MW, Shelton J, Ford LP: Antisense inhibition of human miRNAs and indications for an involvement of miRNA in cell growth and...
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báo cáo hóa học:" Gender and sexuality: emerging perspectives from the heterosexual epidemic in South Africa and implications for HIV risk and prevention" pdf
... the persistence of gender violence remains a worrying continuity that shapes and binds forms of femininity and masculinity Jewkes and Morrell Journal of the International AIDS Society 2010, 13:6 ... hegemonic masculinity involve sexual and other forms of risk taking These include driving cars fast and dangerously, and heavy alcohol consumption; indeed, social norms around alcohol drinking are such ... individual behaviours In real terms, this means focusing attention on building more gender-equitable and caring masculinities, and less acquiescent femininities In so doing, interventions are needed...
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Báo cáo khoa học: " Kinetic modeling of tumor growth and dissemination in the craniospinal axis: implications for craniospinal irradiation" pps
... suspend treatment of the spine temporarily while treatment of the brain continues Since the brain and spine are in communication via the cerebrospinal fluid, holding treatment in one compartment may ... constantly disseminating in the CSF and forming satellite nodules that can then themselves disseminate immediately This is almost certainly not the case for all tumors, especially those early in their ... kshedNb,t,i+γfkadhNb,f,i)] where Ds and Db are the doses administered in a single fraction to the spinal and brain compartments, respectively Scenario I In this scenario (Figure 3), results following a standard course...
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Báo cáo y học: " Reduced peak oxygen uptake and implications for cardiovascular health and quality of life in patients with schizophrenia" ppsx
... least as important as the conventional risk factors for CVD and evaluation of VO2peak should be incorporated in clinical practice Finally, these finding represent an urging need for developing effective ... monitoring and management guidelines for second-generation antipsychotics J Clin Psychiatry 2007, 68:14-18 20 21 Ware JE, Kosinski M, Gandek B: SF-36 health survey: manual & interpretation guide Lincoln, ... The test started from warm-up speed (with minimum 5% inclination) after which the speed or the inclination was increased every minute (0.5-1 kmh-1 and 1-2%, respectively) to a level that brought...
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báo cáo khoa học: " Assisted injection in outdoor venues: an observational study of risks and implications for service delivery and harm reduction programming" pps
... clean injection supplies, injection Page of paraphernalia vending machines may be considered as further novel intervention In addition, the dynamic of ingrained injection routines and assisted injection ... engage in this practice in outdoor venues In the present study, we demonstrated that being female was associated with receiving assistance with injecting in outdoor settings This finding is consistent ... responsibility for the preparation and administration of drugs [23] Further, in our setting, Shannon et al recently demonstrated that individuals involved in sex trade work are being pushed to work and inject...
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báo cáo khoa học: " HIV seroprevalence among participants at a Supervised Injection Facility in Vancouver, Canada: implications for prevention, care and treatment" docx
... were willing to participate in the prospective study following a full explanation, providing a written informed consent, completing an interviewer-administered questionnaire and supplying a blood ... participate in other health and social services The association between intensive cocaine use and HIV infection has been well described in this community and injection cocaine is consistently found to increase ... residence in the Vancouver's Downtown Eastside, daily heroin injection, daily crystal methamphetamine injection, public drug use, requiring help with injecting, sharing other drug using equipment,...
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Báo cáo y học: "RhoA signaling modulates cyclin D1 expression in human lung fibroblasts; implications for idiopathic pulmonary fibrosis" ppsx
... factors for hours for gene expression analysis and 24 hours for protein expression studies The chosen time points and concentrations of growth factors were determined and established in previous and ... expression and induction in cyclin D1 protein, reflecting results of cyclin mRNA expression A representative blot from one of the IPF derived cell lines is shown in Fig 2c Data shown in fig 2a, 2b and ... Simvastatin also induced G1 arrest in the IPF fibroblasts, again overriding inductive effects of TGF -β1 , resulting in suppressed cell proliferation An alternative mechanism for the observed changes in...
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Báo cáo y học: "Predicting iron and folate deficiency anaemias from standard blood testing: the mechanism and implications for clinical medicine and public health in developing countries" ppt
... RBC formation and destruction In so doing it shows the cause for hitherto unexplained observations [13] and predicts other clinical applications for routine blood analysis The model shows that in ... Changes 1in Hb and RDW-CV% with iron deficiency Changes in Hb and RDW-CV% with iron deficiency RDW-CV% indicated by -+Hb indicated by -x- This method cannot distinguish between folate and Vitamin B12 ... stabilizes and the RDW-CV% returns to normal levels The critical finding is that the RDW-CV% becomes abnormal while the Hb and MCV are still within normal range This explains the findings [2,3]...
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Role of hydrogen sulfide in the cardiovascular system implications for treatment of cardiovascular diseases
... 72 4.2.7 Sirus red staining for collagen 73 4.2.8 Toluidine blue staining for mast cells 73 Liu Yi Tong 4.2.9 Immunostaining for renin, mast cells and cell nuclei ... first renin inhibitor, aliskiren, was approved by the Food and Drug Administration for use in the United States in March 2007 Aliskiren binds to the active site of renin and prevents the binding of ... Renin is the rate-limiting enzyme involved in renin-angiotensin system Renin elevation occurs during pathological states of renal ischemia (renin in systematic circulation) or cardiac remodeling...
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Placing Bank Supervision in the Central Bank Implications for Financial Stability Based on Evidence from the Global Crisis
... several countries (including Belgium, Hungary, and the United Kingdom) went on to reform their institutions for financial sector supervision, including bringing bank supervision and macroprudential ... al (2014) examine determinants of the 2007–09 banking We assume, as is common in the literature (Masciandaro, Pansini, and Quintyn 2011), that the mandate for financial stability and macroprudential ... estimating a probit model All robustness tests support and, on occasions, reinforce our baseline results Interestingly, when we use the Reinhart and Rogoff (2011) definition of banking crises, placing...
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Effective and coordination in Lao PDR Policy Implications for power sector development.PDF
... mechanisms for streamlining aid coordination The government made institutional adjustments for aid coordination in 2004, transferring the function to the Ministry of Foreign Affairs The Department of International ... competent people working on the agenda, Laos needs to improve the local capacity Funding for training such as English language training, report writing and basic specialized trainings in order to support ... SWGs for energy and mining The review of continuous effort to improve SWGs, it continues to recommends 19 To clarify roles and responsibilities of SWGs That includes the linkages in the NGPES and...
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Tài liệu ASTHMA MANAGEMENT IN MINORITY CHILDREN: PRACTICAL INSIGHTS FOR CLINICIANS , RESEARCHER AND PUBLIC HEALTH PLANNERS docx
... recruitment and retention are facilitated by incentives, including convenience and comfort factors s The informed consent process and followup efforts can be challenging and time consuming s Understanding ... was publishing and widely disseminating the 1991 Expert Panel Report: Guidelines for the Diagnosis and Management of Asthma A continuing challenge in asthma control efforts is reaching minority ... contingent upon returning them Incentives that were used with success in the five projects included: • Monetary reimbursements (for example, $15 for baseline and final interviews and $10 for...
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Tài liệu The Decline of Traditional Banking: Implications for Financial Stability and Regulatory Policy doc
... In any industry, a decline in profitability usually results in exit from the industry (often by widespread bankruptcies) and a shrinkage of market share This occurred in the banking industry in ... banking institutions Indeed, banks’ loan losses in these countries as a fraction of GNP exceeded losses in both the banking and the savings and loans industries in the United States The International ... alone in losing their monopoly power over depositors Financial innovation and deregulation are occurring worldwide and have created attractive alternatives for both depositors and borrowers In Japan,...
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Global Health in Medical Education: A Call for More Training and Opportunities pptx
... foreign institutions to help develop multidisciplinary curricula in global health and encourages faculty and students from diverse disciplines, including business, law, journalism, and engineering, ... working in international, resource-poor settings We now suggest several steps that can be taken by medical schools to meet the growing interest and demands of medical students for more training and ... students for a year of clinical research training in a developing country In addition, the FIC’s newly established Framework Programs for Global Health provides support for NIH-funded U.S and foreign...
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Tìm thêm: xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn xác định thời lượng học về mặt lí thuyết và thực tế tiến hành xây dựng chương trình đào tạo dành cho đối tượng không chuyên ngữ tại việt nam điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct phát huy những thành tựu công nghệ mới nhất được áp dụng vào công tác dạy và học ngoại ngữ mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ hệ số công suất cosp fi p2 đặc tuyến hiệu suất h fi p2 đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 động cơ điện không đồng bộ một pha sự cần thiết phải đầu tư xây dựng nhà máy thông tin liên lạc và các dịch vụ từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng theo chất lượng phẩm chất sản phẩm khô từ gạo của bộ y tế năm 2008