antibodies to proteus in rheumatoid arthritis patients from norway spain and england
báo cáo khoa học: " Oral bisphosphonate-related osteonecrosis of the jaws in rheumatoid arthritis patients: a critical discussion and two case reports" potx
... therapy in rheumatoid arthritis Joint Bone Spine 2006, 73:349-54 19 Joffe I, Epstein S: Osteoporosis associated with rheumatoid arthritis: Pathogenesis and management Seminars in Arthritis and Rheumatism ... due to a common underlying pathobiology of periodontitis and rheumatoid arthritis [28] The main clinical aspects of patients with RA who develop oral BRONJ include bone exposure, edema, pain and ... Klestov AC, Bartold PM: Is there a relationship between rheumatoid arthritis and periodontal disease? J Clin Periodontol 2000, 27:267-72 28 Modi DK, Chopra VS, Bhau U: Rheumatoid arthritis and...
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Báo cáo y học: "Circulating tumour necrosis factor-α bioactivity in rheumatoid arthritis patients treated with infliximab: link to clinical respone" pot
... osteoprotegerin and soluble receptor activator of nuclear factor kappa B ligand in serum of rheumatoid arthritis patients and their normalization after anti-tumor necrosis factor alpha treatment Arthritis ... (RA) patients treated with (TNF)-α matoid arthritis (RA) patients treated with infliximab Using this bioassay three patterns were observed and linked to the clinical response in the 20 patients ... by rheumatoid arthritis in IL-6 and osteoprotegerin (OPG) production Link between changes (RA) synoviocytes and clinical response by rheumatoid arthritis (RA) synoviocytes and clinical response...
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Báo cáo y học: "DAS28 best reflects the physician''''s clinical judgment of response to infliximab therapy in rheumatoid arthritis patients: validation of the DAS28 score in patients under infliximab treatment" potx
... consent and patients stopped for protocol violation Of the remaining 474 patients, 102 (22%) patients, who were not optimally responding to treatment according to the treating rheumatologist's opinion, ... variables, combined in a model, could discriminate the treating rheumatologist's decision to give a dose increase of infliximab to RA patients not optimally responding to an indicated dose of mg infliximab ... including different joint scores, and serum markers of systemic inflammation Study population A total of 511 patients, suffering from active refractory RA [5], were treated with intravenous infusions...
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Báo cáo y học: " Impact of concomitant DMARD therapy on adherence to treatment with etanercept and infliximab in rheumatoid arthritis. Results from a six-year observational study in southern Sweden" docx
... Maslinski W: Laboratory changes on anti-tumor necrosis factor treatment in rheumatoid arthritis Curr Opin Rheumatol 2003, 15:267-273 21 Lugering A, Schmidt M, Lugering N: Infliximab induces apoptosis ... EULAR standing committee for international clinical studies including therapeutic trials: The EULAR Handbook of Clinical Assessment in Rheumatoid Arthritis Alpen an den Rijn, The Netherlands: Van ... of patients receiving hydroxychloroquine, sulfasalazine, and (to a lesser extent) leflunomide and azathioprine might change over time (HAQ score, CRP level, and DAS28) to complement findings from...
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Báo cáo y học: "Determining a low disease activity threshold for decision to maintain disease-modifying antirheumatic drug treatment unchanged in rheumatoid arthritis patients" docx
... Bergman M, Toloza S, Pincus T, Questionnaires in Standard Monitoring of Patients With Rheumatoid Arthritis Group: Remission and rheumatoid arthritis: data on patients receiving usual care in twenty-four ... method and to develop recommendations for clinicians to use the DAS28 in clinical practice in the area of uncertainty (DAS28 of to 3.2), in order to guide the decision to maintain unchanged or to ... Utrecht Rheumatoid Arthritis Cohort study group: Intensive treatment with methotrexate in early rheumatoid arthritis: aiming for remission Computer Assisted Management in Early Rheumatoid Arthritis...
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báo cáo hóa học:" Do visual analogue scale (VAS) derived standard gamble (SG) utilities agree with Health Utilities Index utilities? A comparison of patient and community preferences for health status in rheumatoid arthritis patients" pptx
... preferences and directly obtained patient preferences in a sample of rheumatoid arthritis patients Methods Study sample A sample of patients with a rheumatologist-confirmed diagnosis of rheumatoid arthritis ... status in stroke patients: interrater and inter-technique comparisons In Values and Long Term Care Edited by: Kane R Lexington, MA: D.C Heath; 1982:191-214 Feeny D, Townsend M, Furlong W, Tomkins ... 0.49 to 0.64 0.46 to 0.62 0.45 to 0.61 0.45 to 0.61 0.42 to 0.59 0.41 to 0.58 0.48 to 0.63 0.45 to 0.61 60% 58% 58% 57% 56% 55% 62% 61% 0.60 0.56 0.55 0.54 0.52 0.50 0.58 0.54 0.52 to 0.66 0.47 to...
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Báo cáo y học: "Serum cartilage oligomeric matrix protein (COMP) decreases in rheumatoid arthritis patients treated with infliximab or etanercept" pot
... rheumatoid arthritis Arthritis Rheum 2001, 44:2009-2017 van den Berg WB: Uncoupling of inflammatory and destructive mechanisms in arthritis Semin Arthritis Rheum 2001, 30:7-16 Feldmann M, Maini ... double-blind, dose-ranging, randomized, placebo-controlled study of recombinant human interleukin-1 receptor antagonist in patients with rheumatoid arthritis: radiologic progression and correlation ... that inflammation and tissue destruction are not directly linked, thus corroborating earlier published Figure Serum COMP (S-COMP) at baseline and after and months in rheumatoid arthritis patients...
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Báo cáo y học: "Differentiation of naive CD4+ T cells towards T helper 2 cells is not impaired in rheumatoid arthritis patients" pps
... activity of interleukin-4 and interleukin-10 in suppression of inflammation and joint destruction in rheumatoid arthritis Arthritis Rheum 2001, 44:3-12 Horsfall AC, Butler DM, Marinova L, Warden ... Berg WB: Role of interleukin-4 and interleukin-10 in murine collagen-induced arthritis Protective effect of interleukin-4 and interleukin-10 treatment on cartilage destruction Arthritis Rheum ... Punnonen J: The presence of interleukin-13 in rheumatoid synovium and its antiinflammatory effects on synovial fluid macrophages from patients with rheumatoid arthritis Arthritis Rheum 1996, 39:1693-1702...
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Báo cáo y học: "Balance between survivin, a key member of the apoptosis inhibitor family, and its specific antibodies determines erosivity in rheumatoid arthritis" ppt
... A, Meineckel I, Gay S, Pap T: Apoptosis in rheumatoid arthritis Curr Opin Rheumatol 2003, 15:274-279 Firestein GS, Yeo M, Zvaifler NJ: Apoptosis in rheumatoid arthritis synovium J Clin Invest ... Concanavalin A, TSST-1, and TNFα leading to a significant release of inflammatory cytokines and chemokines, failed to induce survivin expression by PBMC In contrast, downregulation of survivin expression ... leflunomide, and one patient used azathioprine The inhibitors of TNF-α were used in 47 patients (42 patients in combination with MTX, three patients in combination with azathioprine, one patient in combination...
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Báo cáo y học: "Survival of TNF antagonists in spondylarthritis is better than in rheumatoid arthritis. Data from the Spanish registry BIOBADASER" docx
... events occurring in patients with spondylarthritis and rheumatoid arthritis treated with biologics Spondylarthritis Biologic and total exposure Type of adverse event Rheumatoid arthritis Infliximab ... failed to respond to two NSAIDs and two disease-modifying antirheumatic drugs (DMARDs) In Spain, infliximab was available for clinical use in August 1999, etanercept in April 2003, and adalimumab in ... of Rheumatology This study was funded, in part, by the Spanish Agency for Medicines and Medical Devices (Ministry of Health, Spain) The following is a list of contributors (and centers) in BIOBADASER,...
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Báo cáo y học: "Four-year follow-up of infliximab therapy in rheumatoid arthritis patients with long-standing refractory disease: attrition and long-term evolution of disease activity" pot
... the stop of therapy were 5.4 (SD 1.5) among patients who stopped due to inefficacy, 3.5 (SD 1.3) in patients who stopped due to safety reasons, and 3.0 (SD 1.0) in the patients withdrawn from infliximab ... Our findings also indicate that the decision to continue infliximab therapy is best made using the DAS28 score Competing interests The study was supported by a grant from Centocor BV and Schering-Plough ... treatment of rheumatoid arthritis in patients taking concomitant methotrexate: the ARMADA trial Arthritis Rheum 2003, 48:35-45 Maini SR: Infliximab treatment of rheumatoid arthritis Rheum Dis Clin North...
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Báo cáo y học: "Systemic TNF blockade does not modulate synovial expression of the pro-inflammatory mediator HMGB1 in rheumatoid arthritis patients – a prospective clinical study" ppt
... synovial HMGB1 staining was evident in all nine patients before and during infliximab treatment and was most prominent in the lining layer, in areas with cellular infiltrates and in certain blood vessel ... Denmark) for 15 minutes and with an Avidin/Biotin blocking kit (SP-2001, Vector Laboratories, Burlingame, CA USA) according to the manufacturer's instructions Saponin (0.1% w/v in HEPES pH 7.2) ... PE: Sustained improvement over two years in physical function, structural damage, and signs and symptoms among patients with rheumatoid arthritis treated with infliximab and methotrexate Arthritis...
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Báo cáo y học: " Myeloid dendritic cells correlate with clinical response whereas plasmacytoid dendritic cells impact autoantibody development in rheumatoid arthritis patients treated with infliximab" pdf
... double-stranded DNA induced in rheumatoid arthritis patients following treatment with infliximab, a monoclonal antibody to tumor necrosis factor alpha: findings in open-label and randomized placebo-controlled ... Bienvenu J, Fabien N: Infliximab therapy in rheumatoid arthritis and ankylosing spondylitis-induced specific antinuclear and antiphospholipid autoantibodies without autoimmune clinical manifestations: ... infliximab-treated rheumatoid arthritis patients (a) Circulating plasmacytoid dendritic cell (pDC) levels in rheumatoid arthritis (RA) patients after 14 weeks of infliximab therapy pDC subsets were measured in...
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Báo cáo y học: "Methotrexate therapy associates with reduced prevalence of the metabolic syndrome in rheumatoid arthritis patients over the age of 60- more than just an anti-inflammatory effect? A cross sectional study" pptx
... used to assess LDL, apolipoprotein (Apo) A and ApoB Insulin resistance was evaluated from fasting glucose and insulin using the Homeostasis Model Assessment of Insulin Resistance (HOMA IR) [37] and ... the WHO definition This phenomenon may be explained by differences in the components and cut-off values used in the definitions The WHO is the only definition to include albumin/creatinine ratio ... events and cardiovascular mortality in patients with rheumatoid arthritis Arthritis Rheum 2007, 57:125-132 Stevens RJ, Douglas KM, Saeatzis AN, Kitas GD: Inflammation and atherosclerosis in rheumatoid...
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Báo cáo y học: "Proinflammatory role of amphiregulin, an epidermal growth factor family member whose expression is augmented in rheumatoid arthritis patients" pdf
... these antibodies were measured using flow cytometry, and confirmed to be > 95% pure Synovial fluid was obtained from 24 RA patients and 10 OA patients and venous blood was obtained from 57 RA patients ... Coexpression of phosphotyrosine-containing proteins, platelet-derived growth factor-B, and fibroblast growth factor-1 in situ in synovial tissues of patients with rheumatoid arthritis and Lewis rats with ... AREG protein concentrations in plasma samples from 57 RA patients, 12 OA patients and healthy volunteers and synovial fluid samples from 24 RA patients and OA patients were determined using an AREG...
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Báo cáo y học: "Maintenance of cytomegalovirus-specific CD4pos T-cell response in rheumatoid arthritis patients receiving anti-tumor necrosis factor treatments" potx
... response and suggest that CMV infection remains controlled in treated RA patients latently infected with CMV Materials and methods Patients Patients were included in this study according to several ... were then washed and stained for surface markers (CD28 and CD4), and then permeabilized by using the Becton Dickinson intracellular cytokine kit Cells were then stained for intracellular IFN-γ ... similar to those in previous studies in normal blood donors regarding proliferation [18] and cytokine production by flow cytometry in transplant recipients [37] and HIV patients [36] Contrary to the...
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Báo cáo y học: " Expression of K2P5.1 potassium channels on CD4+ T lymphocytes correlates with disease activity in rheumatoid arthritis patients" potx
... treatment (rituximab) Patients receiving interleukin (IL)-6 receptor blocking antibodies (tocilizumab) were excluded from the primary analysis because of its direct influence on CRP and ESR levels However, ... P, Kleinert S, Tony HP: Sustained remission after combination therapy with rituximab and etanercept in two patients with rheumatoid arthritis after tnf failure: case report Open Rheumatol J 2009, ... 28-joint Disease Activity Score (DAS28) and European League Against Rheumatism response criteria based on Creactive protein against disease progression in patients with rheumatoid arthritis, and...
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báo cáo hóa học: " The agreement between workers and within workers in regard to occupational exposure to mercury in dental practice assessed from a questionnaire and an interview" potx
... misinterpreted the question in the questionnaire and have regarded it as relating to the small mortar used to handle the amalgam subsequent to the mixing in a Dentomat or a capsule In the interview, ... alloy and mixed it in a mortar? If yes: In that case, when and for how many years? From year to year Have you mixed amalgam in a Dentomat? Yes-no Did you use a Dentomat (semi-automatic device) to ... preparation methods regarding exposure to mercury (using copper amalgam and using a Dentomat) were still in use, and when many dental clinics changed from these methods to more modern ones (e.g...
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Báo cáo y học: "CD147 overexpression on synoviocytes in rheumatoid arthritis enhances matrix metalloproteinase production and invasiveness of synoviocytes" pptx
... analyses of and in undifferentiated and differentiated THP-1 cellssynoviocytes (FLS) from rheumatoid arthritis (RA) patients, from osteoarthritis (OA) patients, and in undifferentiated and differentiated ... non-reducing conditions using 8% separating gel containing 0.1% gelatin The gels were then washed twice in 2.5% (w/v) Triton X-100 for 30 minutes at room temperature to remove SDS and were incubated in ... in both autocrine and paracrine stimulation of MMPs From the findings that homophilic CD147 binding has occurred in the context of both heterotypic and homotypic cell–cell interactions and that...
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Báo cáo y học: "Elevated autoantibody content in rheumatoid arthritis synovia with lymphoid aggregates and the effect of rituximab" ppt
... Effect of rituximab on circulating and synovial autoantibodies and immusynovial autoantibodies and noglobulin (a) Circulating levels of autoantibodies and total IgM and IgG weeks after rituximab ... and/ or varying autoantibody concentrations in serum To correct for these variables, paired synovia and sera were obtained from 11 RA and OA patients, and albumin levels determined alongside antibodies ... Significant enrichment of total IgM and IgG in rheumatoid arthritis (RA) synovia Serum-normalized levels of (a) total IgM and (b) total IgG in extracts from osteoarthritis (OA) (n = 6) and RA (n = 11)...
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