... was studied withthe acoustic standing wave being applied in a laminar flow within a microchannel Yasuda and his colleagues applied the acoustic standing wave in a laminar flow within their microchannel[35] ... simulate and predict the bifluid flow, together withthe movement ofthe interface between the two parallel micro fluids; 10 Chapter To develop a theoretical model ofthe particle motion within the ... theoretically The hydrodynamic model would contribute to the prediction ofthe bi-fluid flow andthe understanding ofthe factors that affect the flows andthe interface This model is also necessary for the...
... However they are beyond the scope of this studyThestudy only focuses on the verbal aspects andthe data analysis of politeness and safe and unsafe topics Thestudy is limited within the first ... hurt and loss offace is a consequence inthe communication Inthe social meetings ofthe human beings, the participants their best to communicate with their positive face which reflects their ... Brown and Levinson (1987) and Politeness Principles Maxims by Leech (1983) Of all, Brown and Levinsons theory is the most outstanding and most quoted Inthe Politeness theory by Brown and Levinson...
... only studied the binding ofthe nonsymmetric and more soluble compound using intermolecular NOEs Inthe : complex withthe protease, the proton resonances ofthe phthalazine ring of were too broad ... residing inthe substrate-binding site A NOESY spectrum ofandinthe presence of a small quantity of protease revealed an intermolecular cross-peak between the methyl group ofandthe phthalazine ... observed inthe crystal structures ofthe complex with peptidic inhibitors [4–6], in which the C-terminal b-hairpin of NS2B is positioned near the substrate-binding site rather than far away as in the...
... Topline Findings • April 13, 2011 Overview of findings Background Slover Linett Strategies Inc and mStoner partnered with CASE for the second year in a row in order to research educational institutions ... (on par with last year’s response) across all types of institutions – a testament to the interest in this topic We are just beginning to mine the data from this second round of research and will ... current involvement withthe use of social media Another unit manages all of our social media activities, without any input from us Another unit manages all of our social media activities, with input...
... taking informed consent of parents of patients prior being included into thestudyand was authorized by the local ethical committee Thestudy was performed in accordance withthe Ethical standards ... 30 points for amount of pain; of 20 points each for level of activity and patient satisfaction; andof 10 points each for motion ofthe ankle and foot, position ofthe heel during stance, and ... deformity ofthe heel, adduction ofthe foot, and toeing in [4] The ankle should be in dorsiflexion in an attempt to prevent equinus; and this is accomplished by bending the bar 10-15 degrees with the...
... taking informed consent of parents of patients prior being included into thestudyand was authorized by the local ethical committee Thestudy was performed in accordance withthe Ethical standards ... 30 points for amount of pain; of 20 points each for level of activity and patient satisfaction; andof 10 points each for motion ofthe ankle and foot, position ofthe heel during stance, and ... deformity ofthe heel, adduction ofthe foot, and toeing in [4] The ankle should be in dorsiflexion in an attempt to prevent equinus; and this is accomplished by bending the bar 10-15 degrees with the...
... to the development of study, in gathering and analyzing the data, andinthe writing and editing processes ofthestudy Acknowledgements Fidia S.p.A (Padova, Italy) provided Hyalubrix® andthe ... determination ofthe change inthe Lequesne index ofthe hip, comparing IA HA with IA mepivacaine at 26 weeks Secondary endpoints were pain intensity (recorded on a 10 cm VAS), patient record of ... at baseline than that of patients treated with local anesthetic Interestingly, the reduction in NSAID intake was 49.4% after months inthe Hyalubrix® group and 24.6% inthe local anesthetic group...
... area under the curve (AUC) of 0.69 The combination of slightly increased accuracy and positive likelihood ratios remaining above suggested some gain in informative value of lowering the threshold ... predictive value of lowering the threshold for anti-CCP positivity to 10 units/ml This is in line withthe findings in a recent study [18] We believe that the clinician should be aware ofthe potential ... than the recommended cut-off of 25 units/ ml Likelihood ratios and their 95% confidence intervals were calculated for these alternative cut-offs To assess the effect of increasing levels of anti-CCP...
... improve the photoactivity of TiO2 The mechanism ofthe photoactivity improvement was mainly ascribed to the inhibiting effect ofthe deposited precious metals on the recombination ofthe electron/hole ... generate initial active groups, including electrons (e-) and holes (h+), which can react withthe reactants The generation mechanism of e- and h+ in photocatalysts involves the photo excitation ofthe ... mixture of both components The importance in maintaining sufficiently 20 Chapter available surface of TiO2 was also emphasized to obtain a good interaction withthe species present inthe solution...
... 2006 The Authors Journal compilation ª 2006 FEBS studystudystudystudystudystudystudystudystudystudystudystudystudystudy 639 Delineation of ExoS residues L Yasmin et al Fig Interaction ... shown) The basic cluster of amino acids inthe binding groove of 14-3-3, including amino acids Lys-49, Arg56, Lys-120 and Arg-127, in an otherwise acidic molecule, are important for the interaction ... activity in vivo We have approached these questions using a strategy of single amino acid site-directed mutagenesis Delineation of ExoS residues ofthe cofactor interaction domain within ExoS...
... clarified in detail and could play a key role inthe detoxification processes In this study we examined the role of Bcp2 in order to increase the knowledge ofthe enzymatic activity involved inthe ... 2-Cys Prxs, the largest Prx class, is their second redox-active cysteine, the resolving cysteine (Cys-SR) In typical 2-Cys, Sp at the N terminus and SR at the C terminus ofthe protein belong to ... to the cultures inhibits growth without killing the cells The hybridizing band inthe northern analysis showed the expected size of about 680 bp indicating that the gene is transcribed as a monocistronic...
... [19,22] The b sheet of EGF may bind to domain I of ErbB-1, andthe other surface ofthe ligand binds to domain III ofthe receptor Recently, Gly441 ofthe ErbB-1 domain III was proposed to be involved ... binding (Fig 2) Therefore, the contributions of domains III and I inthe EGF-induced autophosphorylation of ErbB-1 were fully consistent with those inthe EGF binding Furthermore, the extent of ... the EGF receptor A deletion inthe N-terminal region of domain I impaired the EGF binding of ErbB-1 [21] The N-terminus of EGF was linked to Tyr101 in domain I by using a covalent cross-linking...
... than the y-intercept ofthe asymptote Comparison ofthe terms inthe denominators of Eqns and shows that for positive values of Kmi, the terms ofthe denominator of Eqn will always be less than the ... surface charge extending along the left- and righthand sides ofthe ring in Fig 10A [23] This region is comprised of ve histidines, nine lysines, and four arginines in each subunit The pH prole data ... that as the pH increases, there is still sufcient protonation ofthe lysines at pH 10, along withthe fully protonated arginines, to interact withthe heparin to delay inactivation ofthe enzyme,...
... implicated in cisplatin resistance, i.e decreased drug uptake, insufficient DNA-binding ofthe drug, increased DNA-repair of cisplatin adducts and failure of induction of apoptosis, reviewed in [2,5,7] ... participated inthe data collection JE participated inthe design ofthestudyand helped draft the manuscript MAK assisted withthe data collection and helped draft the manuscript IBJ assisted withthe ... two independent patient cohorts demonstrating that expression ofthe RNA- Page 11 of 12 binding protein RBM3, both at the mRNA and protein levels, is associated with a good prognosis in epithelial...
... pedicles ofthe LIV are more leveled, and this may reduce the interspace angle related withthe loss of coronal Cobb angle ofthe main curve during follow-up Till now, the changes ofthe interspace ... angle, the more shear stress on the next caudal vertebra and increased risk of degeneration in future Thecorrectionofthe interspace angle could reduce the occurrence of future low back pain and ... cases of King type II and 11 cases of King type IV that underwent posterior or combined anterior and posterior correctionwith at least year follow-up Inthe 15 King type II patients andthe King...
... agent, since they promote a significant delay inthe conidia germination ofthe pathogen P expansum and an inhibition of patulin production Nevertheless, the performance of LF23 inthe control of patulin ... system withthe standard curve obtained by DNA extracted from the contaminated matrix lead to a rough quantification ofthe P expansum DNA present inthe contaminated apples inthe presence or inthe ... phytoalexins assayed (Sanzani, 2007) Another study (Mossini et al., 2004) reports the inhibiting effect of Azadiracta indica leaf extracts on the growth and patulin production of a P expansum strain without...
... covered 10-15% ofthe examined area, and mainly concerned the cartilageproducing areas In one marginal large area ofthe tumour, the lobules were not as well formed or defined, andthe tumour cells ... bone (A) The mass expanded into the cranial cavity (B) and severely compressed the cerebellum andthe right occipital lobe (encircled C and D before and after the removal ofthe meninges, respectively) ... contained mainly chondroid tissue inthe center and had thinner fibrous septae (Fig 2D) The mitotic index of these foci was low and small necrotic foci were present inthe center ofthe larger...
... described inthe Introduction, the aim of studying the triterpenoids is to develop a therapeutic agent for the treatment of arthritis We were therefore interested in studying the effects of CDDO in ... were induced with IL-1, a known pro-inflammatory mediator in vivo in joint tissues [23] It was shown that CDDO could inhibit the IL-1-induced expression of these pro-inflammatory MMPs These findings ... difference inthe action ofthe inhibitor on the expression of each enzyme Previously, withthe use of Northern blotting, dose–response assays in SW-1353 cells showed that 300 nM was the lowest dose of...
... signet ring cancer as the leading type [15] In general, mucinous and signet ring tumours have been associated with higher mortality compared with carcinoma without a mucin component Inthe young, ... (3) and II I1, 111 and 1V II,111 and 1V AJCC stage (4) 1,11 and III IV Resection Margin R0 R1 Perineural invasion + Lymphatic invasion - Vascular invasion - + + Tumor margin Pushing Infiltrating ... from the West; 2.8% inthe United States [9], 3% in France [9] and 5.5% in New Zealand [6,15] The high percentage reported in developing countries may be due, in part, to the higher population of...
... purposes) The aim ofthe current study was to examine the gene and protein expression of MMP-10 in histologically normal human IVD and compare it with that of both non-painful and painful degenerate ... correlates with increases inthe expression of MMP-10 The findings also demonstrate a strong correlation between increases in NGF and increases inthe pain-associated neuropeptide substance P in surgical ... in 4% paraformaldehyde/phosphate-buffered saline and processed into paraffin wax Five-micron sections from the tissue blocks were cut and stained with haematoxylin and eosin, andthe degree of...