amp 945 2i domain in the amp 945 2 amp 946 1 integrin and induces clustering of the receptor molecules
Báo cáo y học: "Bench-to-bedside review: Biotrauma and modulation of the innate immune response" pps
... RJ, Strieter RM: Critical role for CXCR2 and CXCR2 ligands during the pathogenesis of ventilator-induced lung injury J Clin Invest 20 02, 11 0 :17 03 -17 16 Steinberg JM, Schiller HJ, Halter JM, Gatto ... immune therapy may be a feasible option in the future to prevent or reduce VILI Competing interests The author(s) declare that they have no competing interests References 10 11 12 13 14 15 16 Conclusion ... applied to injured lungs, causes the release of inflammatory mediators, which may then pass on to the circulation [9 , 21 ,24 ,27 ] The main theory in support for increasing levels of inflammatory...
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Báo cáo y học: " Characterization of the innate immune response to chronic aspiration in a novel rodent model" ppsx
... Med 20 03, 11 5(Suppl 3A):39S-44S Page 10 of 12 (page number not for citation purposes) Respiratory Research 20 07, 8:87 10 11 12 13 14 15 16 17 18 19 20 21 22 23 24 Ducolone A, Vandevenne A, Jouin ... of adhesion molecules and the production of additional cytokines, including IL-1alpha and IL-1beta TNF-alpha also plays a critical role in leukocyte trafficking and homing of T and B cells [22 ,23 ] ... http://respiratory-research.com/content/8 /1/ 87 Figure Instillation of fluid into the left lung Instillation of fluid into the left lung The instillation of gastrograffin into the distal trachea of sedated rats in the left lateral...
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Báo cáo khoa học: Proteolytic activation and function of the cytokine Spatzle in the innate immune response of a lepidopteran insect, Manduca sexta ppt
... Journal 27 7 (20 10 ) 14 8 1 62 ª 20 09 The Authors Journal compilation ª 20 09 FEBS C An et al 12 13 14 15 16 17 18 19 20 21 22 23 24 M et al (20 06) A Spatzle-processing enzyme required for toll signaling ... Adaptive evolution of relish, a Drosophila NF-kappaB ⁄ IkappaB protein Genetics 15 4, 12 3 1 12 3 8 FEBS Journal 27 7 (20 10 ) 14 8 1 62 ª 20 09 The Authors Journal compilation ª 20 09 FEBS 16 1 Manduca sexta Spatzle ... identical except for a nine residue segment present in 11 .7 but not in 11 .15 , caused by the use of an alter- FEBS Journal 27 7 (20 10 ) 14 8 1 62 ª 20 09 The Authors Journal compilation ª 20 09 FEBS C An et...
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Báo cáo Y học: Modulation of the oligomeric structures of HIV-1 retroviral enzymes by synthetic peptides and small molecules pptx
... Method of analysis of PR dimerization Ref 45 >10 0 10 0 Kinetic analysisa Kinetic analysis Kinetic analysis [16 ] [19 ] [20 ] Kinetic Kinetic Kinetic Kinetic Kinetic [20 ] [20 ] [ 21 ] [ 21 ] [ 21 ] 12 0.5 0 .15 ... (residues 1 85, 11 8 15 5), palm (86 11 7, 15 6 23 7) and thumb (23 8– 318 ) The DNA polymerase catalytic aspartate residues (D 110 , D185, and D186) reside in the palm subdomain A fourth subdomain, termed the ... single region in the palm domain of p66 (D86-L 92) interacts with two regions of the fingers of p 51 (P 52- P55 and S135-P140) The RNase H residues 537–546 in the p66 subunit interact with the p51...
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Báo cáo khoa học: The starch-binding capacity of the noncatalytic SBD2 region and the interaction between the N- and C-terminal domains are involved in the modulation of the activity of starch synthase III fromArabidopsis thaliana pdf
... CD+D 12 3 CD–D23 CD–St2 .1 CD–St2 .2 CD–St2.3 CD+D23 CD+St2 .1 CD+St3.3 CD–D3 4.08 0 .28 0.95 2. 56 2. 39 1. 77 1. 68 0. 62 0.59 0. 81 1.74 1. 1 1. 0 1. 1 2. 0 1. 8 1. 1 0.9 1. 8 1. 6 1. 1 1 .2 Vmax (unitsÆmg )1) nH ... CD+St2 .1 CD+St3.3 CD–D3 0 .28 2. 69 0. 32 0.65 0.59 1. 71 1.76 0.78 1. 05 1. 11 1.87 1. 0 1 .2 0.9 1. 1 0.8 1 .2 0.9 1. 0 1. 3 1. 1 1. 3 ± ± ± ± ± ± ± ± ± ± ± 0.05 0 .16 0. 12 0 .15 0.07 0 . 21 0 .14 0 .13 0.09 0 .10 ... proteins for glycogen Isoform S0.5 (mgÆmL )1) nH CD+D 12 3 W366A CD+D 12 3 Y394A CD+D 12 3 W366AY394A CD–D 12 3 W366A CD–D 12 3 Y394A CD–D 12 3 W366AY394A 1. 73 0. 32 3.0 1. 55 0 .26 2. 99 1. 0 1 .2 1. 8 0.8 1. 0 1. 1 ± ±...
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Báo cáo khoa học: " Cisplatin chemotherapy (without erythropoietin) and risk of life-threatening thromboembolic events in carcinoma of the uterine cervix: the tip of the iceberg? A review of the literature" docx
... Perforation Cis = Cisplatin 5FU = Fluorouracil WP = Whole Pelvis Gy = Gray Page of (page number not for citation purposes) Radiation Oncology 20 06, 1: 14 10 11 12 13 14 15 16 17 18 19 20 21 http://www.ro-journal.com/content /1/ 1 /14 ... http://www.ro-journal.com/content /1/ 1 /14 develop thromboses [10 ,11 ] Simply from their malignancy, in the absence of chemotherapy, one might expect more than reported cases of severe thrombotic events out of the 1 424 patients ... Suppl) :22 10 - 21 Pearcey R, et al.: Phase III trial comparing radical radiotherapy with and without cisplatin chemotherapy in patients with advanced squamous cell cancer of the cervix J Clin Oncol 20 02, ...
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Báo cáo y học: "Bench-to-bedside review: Functional relationships between coagulation and the innate immune response and their respective roles in the pathogenesis of sepsis" ppsx
... recognition in the innate immune system These include the serum complement [11 ], C-reactive protein (CRP) [10 ], mannose binding lectin [9], LPS-binding protein (LBP), and soluble CD14 [ 12 ] The cell ... leucine-rich repeats in their ectodomain, a transmembrane domain, and an intracellular domain that bears striking homology to the intracellular domain of the IL -1 type receptor This region of homology ... activity of APC is not shared by antithrombin [1 ,2] APC actually binds to the active site of PAI -1 and as such blocks the serine protease inhibitor actions of PAI -1 [2, 10 0 ,10 1] The reaction of APC...
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Báo cáo y học: "Apoptosis resistance in HIV-1 persistently-infected cells is independent of active viral replication and involves modulation of the apoptotic mitochondrial pathway" pot
... Cells U1 Cells + PMA 14 .07 ± 0. 01 14.08 ± 0. 01 1.06 ± 0.03 1. 05 ± 0.03 14 .14 ± 0.05 12 . 86 ± 0.90 1. 60 ± 0.03 51. 96 ± 9 .20 18 .26 ± 0.80 1 52. 04 ± 1. 50 4 .18 ± 1. 11 1 91. 76 ± 0.48 HIV -1 persistently-infected ... apoptotic stimuli, including acute human immunodeficiency virus-type (HIV -1) infection British journal of haematology 19 95, 89 (1) :24 -33 14 15 16 17 18 19 20 21 22 23 24 25 26 27 28 29 30 Mahlknecht ... with H2O2 and 40% with STS; Jurkat: 23 % with H2O2 and 64% with STS) compared with H9/HTLVIIIB and J1 .1 cells respectively (H9/HTLVIIIB: 30% with H2O2 and 26 % with STS; J1 .1: 8% with H2O2 and 3.6%...
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Báo cáo y học: " Early alterations of the innate and adaptive immune statuses in sepsis according to the type of underlying infection" docx
... 48 (26 .2) 19 (19 .6) 19 (19 .0) 16 (26 .2) 14 ( 21 .9) Heart failure 23 ( 12 . 6) 14 (14 .4) (9.0) 13 ( 21 .3) 11 (17 .2) COPD 15 (8 .2) Gogos et al Critical Care 20 10 , 14 :R96 http://ccforum.com/content /14 /3/R96 ... ± 11 4 81. 3 15 0 02. 2 ± 727 2.8 15 595.7 ± 7 027 .8 13 755.9 ± 95 51. 8 13 905.7 ± 828 9 .2 NS Sepsis/severe sepsis-shock 14 1/ 42 56/ 41 70/30 23 /38 22 / 42
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Báo cáo sinh học: "∆RR vaccination protects from KA-induced seizures and neuronal loss through ICP10PK-mediated modulation of the neuronal-microglial axis" docx
... fused in frame with ICP10PK, giving rise to a 17 5 kDa protein (p175) p175 retains the TM and EC domains of the wild type ICP10 protein and it is under the direction of the authentic ICP10 promoter ... 0.0 01) increase in the % TUNEL+ cells ( 32. 6 ± 5 .2 and 21 .8 ± 3.3% for EOC20 and EOC2, respectively), but this increase was not seen in ∆RR-infected cells (13 .8 ± 1. 9 and 10 .2 ± 1. 4% for EOC2 or ... Enemies Within Science 19 98, 28 1( 53 81) :13 12 - 13 16 20 21 22 Carson MJ, Doose JM, Melchior B, Schmid CD, Ploix CC: CNS immune privilege: hiding in plain sight Immunol Rev 20 06, 21 3:48-65 Minghetti...
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Tài liệu Báo cáo khoa học: Modulation of the enzymatic efficiency of ferredoxin-NADP(H) reductase by the amino acid volume around the catalytic site pptx
... 0. 82 25 0 .20 9.97 0. 011 0 .14 0. 018 0.00 2. 86 0.54 4.58 3.07 4 .28 41 22 37 87 29 31 38 31 31 12 0 18 18 ± ± ± ± ± ± 32 42 ± ± ± ± ± ± 22 15 0.5 0.04 0.04 ± ± ± ± ± ± 0.04 0.50 0.003 0. 01 0.0 02 ± ... WT C266A L268V C266AL268A C266L C266M 21 .5 25 .0 –96 .2 53 .2 55.5 2. 2 0 .20 4.6 0.004 ND ND ± ± ± ± kcat ⁄ Km (lM )1 s )1) kcat (s )1) 0.4 0.03 0.8 0.0 01 1. 62 0.74 1. 08 0. 016 ND ND ± ± ± ± 0 .14 0.03 ... 0.08 0.0009 In the presence of NADP+ (KdP)b In the absence of NADP+ (KdA)b 0.73 3.70 0 .23 4.00 ND ND 5 .16 2. 78 2. 80 2. 74 2. 86 3.53 0.68 1. 02 2.69 2. 20 2. 88 2. 77 ± ± ± ± 0 .19 0.70 0.05 1 .22 ± ± ±...
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Báo cáo khóa học: Collectins Players of the innate immune system docx
... Activation of human monocytes by strepto- 11 7 11 8 11 9 12 0 12 1 12 2 12 3 12 4 12 5 12 6 12 7 12 8 12 9 13 0 13 1 1 32 13 3 coccal rhamnose glucose polymers is mediated by CD14 antigen, and mannan binding protein inhibits ... Overath, P & Aebischer, T (19 97) Secreted proteophosphoglycan of 12 4 8 J K van de Wetering et al (Eur J Biochem 27 1) 19 9 20 0 20 1 20 2 20 3 20 4 20 5 20 6 20 7 20 8 20 9 21 0 21 1 21 2 21 3 21 4 Leishmania mexicana ... K.B.M (19 97) Lung surfactant proteins A and D can inhibit specific IgE binding to the allergens of Aspergillus fumigatus and block 18 4 18 5 18 6 18 7 18 8 18 9 19 0 19 1 1 92 19 3 19 4 19 5 19 6 19 7 19 8 allergen-induced...
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Báo cáo khoa học: Copper-containing nitrite reductase fromPseudomonas chlororaphis DSM 50135 Evidence for modulation of the rate of intramolecular electron transfer through nitrite binding to the type 2 copper center pot
... DSM 5 013 5 ND, not determined g-values 0.0 01, A-values 0 .1 Cu Az (mT) Cu center gz gy gx T1Cu T2Cu As-puried With NO2 2. 220 2. 0 52 2.036 5.8 2. 350 2. 34 2. 11 0 ND 2. 040 ND 10 .7 12 . 0 ể FEBS 20 04 ... CoCl2, 0.6 and Na2B2O7, 0 .1 The optical density, the concentrations of nitrate [17 ] and nitrite [18 ], the pO2 and the pH of the medium were monitored, and the composition of the gaseous phase in ... (19 76) Assays of proteins in the presence of interfering materials Anal Biochem 70, 24 12 5 0 21 Laemmli, U K (19 70) Cleavage of structural proteins during the assembly of the head of bacteriophage...
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Báo cáo khoa học: Signaling events mediating activation of brain ethanolamine plasmalogen hydrolysis by ceramide pot
... sphingomyelinase 17 9.6 64.7 21 3.7 1 32. 9 96.4 20 2.4 14 5.7 22 7.3 ± ± ± ± 26 .3 10 .3* 44.5 10 .3* ± ± ± ± 19 .0 37 .2* 28 .0 21 .9* * P < 0.05 compared with their respective controls Table Effect of endothelin -1 ... AA Control Sphingomyelinase C2-Cer 10 30 ± 18 1 8 92 ± 15 8 9 42 ± 20 6 24 266 ± 5488 310 61 ± 25 75* 29 611 ± 24 55* * P < 0.05 compared with their respective controls radioactivity had increased by nearly ... brains were preincubated in the presence of labeled precursors: lCi (0 .2 lCiÆmL )1) [1- 14C]arachidonic acid [2] or 50 lCi (2 lCiÆmL )1) [2- 14 C]ethan -1- ol -2- amine hydrochloride [19 ] at 37 °C in...
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Báo cáo Y học: Irregular spiking in free calcium concentration in single, human platelets Regulation by modulation of the inositol trisphosphate receptors ppt
... determined Ca2+ release (% of control) Agonist Agonist, no heparin InsP3, no heparin InsP3 with heparin None + PGE1 Thrombin Thimerosal + PGE1 U73 12 2 + PGE1 – – ND 8± 15 ± 4 72 ± 495 ± 10 0 46 13 9 21 7 ... effects of heparin and PGE1 on InsP3-evoked Ca2+ release were not in uenced by U73 12 2 (Table 2) These data thus suggest that InsP3 and U73 12 2 have additive effects on Ca2+ release from intracellular ... (1, 4,5) P3-stimulated Ca2+ mobilization in hepatocytes J Biol Chem 26 8, 1 3 21 4 1 322 0 49 Tertyshnikova, S & Fein, A (19 98) Inhibition of inositol 1, 4,5-trisphosphate-induced Ca2+ release by cAMP-dependent...
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Báo cáo khoa học: Modulation of the Arabidopsis KAT1 channel by an activator of protein kinase C in Xenopus laevis oocytes potx
... Journal 27 7 (20 10 ) 23 18 23 28 ª 20 10 The Authors Journal compilation ª 20 10 FEBS 23 25 Phosphorylation of KAT1 channel 26 27 28 29 30 31 32 33 34 35 36 37 38 A Sato et al phosphorylation of the inactivation ... dependence of inward-rectifying potassium channels on cytosolic free calcium concentration increase evoked by hyperpo- 13 14 15 16 17 18 19 20 21 22 23 24 25 larization in guard cells Plant Physiol 11 9, ... of the oocyte endogenous PKC by the application of B 1 .2 T45A T308A S 312 A S589A S590A S641A 0.6 0.4 0 .2 0 10 20 30 37.5 Time (min) A 1 .2 WT (no addition) 0.8 I/Icontrol 1 0.8 0.6 T22A S44A S 12 5 A...
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Báo cáo khoa học: Modulation of the endocannabinoid system by focal brain ischemia in the rat is involved in neuroprotection afforded by 17b-estradiol pdf
... activity [pmolÆmin )1 (mg protein) )1] 22 ± 25 ± CB1 receptor binding [fmolÆ(mg protein) )1] 19 0 ± 20 18 0 ± 20 ER antagonist ICI1 82 780 (0 .25 mgÆkg )1, intraperitoneal, h prior to E2) was able to significantly ... released into the extracellular space and interact with type and type cannabinoid (CB1 and CB2) receptors, non-CB1 ⁄ non-CB2 receptors, and noncannabinoid receptors, including the type vanilloid receptor ... a dose of 0 .20 mgÆkg )1 ICI1 82 780 was dissolved in 4% dimethylsulfoxide in vegetable oil and administered intraperitoneally at a dose of 0 .25 mgÆkg )1, h before E2 SR1 417 16 was dissolved in vegetable...
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Báo cáo hóa học: " Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke" ppt
... stem cells: neural induction and transplantation in a mouse ischemic stroke model J Neurosci Res 20 07, 85 :18 51- 18 62 Page 10 of 10 10 11 12 13 14 15 16 17 18 19 20 21 22 23 Stampachiacchiere B, ... (0.36 1. 52 (0.34 1 .22 (0. 51 1. 42 ± 0 .11 (0.58 ± 0 .25 ) 1 .24 ± 0.07 (0.64 ± 0 .15 ) 1. 18 ± 0.04 (0.7 ± 0 .17 ) Sham-operated normal rats (n = 10 ) two were comparable (p > 0.05) From weeks two to four, the ... of interest [3 ,10 ,11 ] The low degree of differentiation and integration of the transplanted cells in the parenchyma often correlated poorly with the improved functional benefits [ 12 , 13 ] As there...
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Báo cáo lâm nghiệp: " A comparison of the photosynthetic radiation response of Scots pine shoots in direct and diffuse radiation" pot
... distribution of irradiance on the needle surface area was simulated In the 2nd case, length of the photon pathway within the needle before reaching the point under consideration the Results a needle In the ... (Fig B), the rate of photosynthesis represents the photosyn- photosynthetic units were represented by points within the needles and the irradiance (the photon field strength) at these points was ... transmission of radiation within thetic response per unit of intercepted radiation and the difference between the respective rates of photosynthesis result from differences in the distribution of radiation...
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