adult neural stem cells identity and regulation

... adult- derived neural progenitor and stem cells [39] Self-renewing multipotent neural progenitor and stem cells have been isolated and characterized in vitro, from various regions of the adult mammalian ... human biopsies and post-mortem tissues [35] It is hypothesized that newborn neuronal cells in the adult brain originate from residual stem cells The existence of stem cells in the adult brain suggests ... self-repair and that newborn neuronal cells may contribute to the functioning, and physioand pathology of the CNS [36] However, adult NSCs remain elusive cells and to be unequivocally identified and...

Ngày tải lên: 08/08/2014, 17:20

... change a neural stem cell’s fate Under certain conditions, neural stem cells have been induced to differentiate into cells outside the expected neural lineage and conversely, stem cells from nonneural ... Raay and Michael R Stark 223 21 Gene Therapy Using Neural Stem Cells Luciano Conti and Elena Cattaneo 233 22 Modeling Brain Pathologies Using Neural Stem Cells Simonetta Sipione and ... “Isolation and Culture of Neural Stem Cells introduces the reader to different sources of stem/ progenitor cells and provides a wide range of conditions for their selection, nourishment, growth and...

Ngày tải lên: 11/04/2014, 09:58

... Adult mesenchymal stem cells: characterization, differentiation, and application in cell and gene therapy J Cell Mol Med 2004, 8:301-316 31 Tuan RS, Boland G, Tuli R: Adult mesenchymal stem cells ... multipotent adipose-derived stem cells Stem Cells 2006, 24:2412-2419 Kleber M, Sommer L: Wnt signaling and the regulation of stem cell function Curr Opin Cell Biol 2004, 16:681-687 Boland GM, Perkins G, ... expansion of stem cells, increased in vivo reconstitution of hematopoietic lineages, and Wnt3a-specific maintenance of skin and intestinal stem cell populations [18] Because stem cells may share...

Ngày tải lên: 09/08/2014, 10:20

... the term neural stem cell”, and the numerous lineage mapping and genetic studies in recent years have given rise to a number of varied ways of characterizing and classifying NSCs and neural progenitors ... HUMAN EMBRYONIC STEM CELL-DERIVED NEURAL STEM CELLS: DERIVATION, DIFFERENTIATION AND MICRORNA REGULATION KWANG WEI XIN TIMOTHY (B.Sc (Hons), NUS) A THESIS ... uniformly expressed in early neuroectodermal cells (cells from which neural progenitors and all other neural cell types originated) derived from fetuses and from hESCs (Pankratz et al., 2007), thus...

Ngày tải lên: 10/09/2015, 09:08

... orders@intechweb.org Neural Stem Cells and Therapy, Edited by Tao Sun p cm ISBN 978-953-307-958-5 Contents Preface IX Part Chapter Characterization of Neural Stem Cells Neural Stem Cells from Mammalian ... Bian and Tao Sun Part Neural Stem Cells and Therapy 257 Chapter 13 Neural Stem/ Progenitor Cell Clones as Models for Neural Development and Transplantation 259 Hedong Li, He Zhao, Xiaoqiong Shu and ... history and the most advanced discoveries in neural stem cells This book provides the strategies and challenges of utilizing neural stem cells for therapy of neurological disorders and brain and...

Ngày tải lên: 30/03/2014, 23:20

... Human neural stem cells can migrate, differentiate, and integrate after intravenous transplantation in adult rats with transient forebrain ischemia Neurosci Lett 2003, 343:129-133 Evans GR, Brandt ... might induce NSC into progenitors and effecter cells of the neural lineage that would enhance regeneration and alleviate degeneration Besides, low immunogenicity and antigenicity are the fortes ... latency, threshold and amplitude of electromyogram and number, thickness, circumference and area of myelinated nerve fibers derived from rabbits with and without facial nerve injury and repair using...

Ngày tải lên: 18/06/2014, 15:20

... engineering and regeneration [134] Mesenchymal stem cells versus embryonic stem cells Embryonic stem (ES) cells are derived from the inner cell mass of the embryonic blastocyst These cells can ... ‘bone marrow stem cell’, which is often used for either hematopoietic or mesenchymal stem cells, the central nervous system stem cell, the hepatic stem cell, etc.? If many stem cells are found ... supports the survival and differentiation of stem cells These complementary approaches have been used to compare different groups of stem cells in order to identify core stem genes and to examine...

Ngày tải lên: 09/08/2014, 01:21

... breast cancer 22 1.4 Stem cells 1.4.1 Adult stem cells 1.4.1.1 Neural stem cells 1.4.2 Induced pluripotent stem cells 1.5 Stem cell as a vehicle for cancer gene therapy 1.5.1 Stem cell based cancer ... al., 2001) Stem cells as delivery vehicles have been shown to enhance gene delivery efficiency (elaborated in section 3.1) 1.4 Stem cells 1.4.1 Adult stem cells (ASCs) Adult stem cells (ASCs), ... pluripotent stem cell derived -neural stem cell human induced pluripotent stem cell derived -neural stem cell expressing CodA human induced pluripotent stem cell derived -neural stem cell expressing Fcy...

Ngày tải lên: 09/09/2015, 18:56

... 1.4.3 Stem cells and cancer 14 1.5 Neural development 16 1.6 Neural stem cells 19 1.6.1 Embryonic neural stem cells 20 1.6.2 Adult neural stem cells ... during injury, stem cells can adopt this form of cell division to expand and replenish the depleted stem cell pool (Morrison and Kimble, 2006) 1.4 1.4.1 Types of stem cells Embryonic stem cells During ... maintain these cells in an undifferentiated, quiescent state For stem cells to be activated, the niche environment must change (Fuchs, 2007) 1.4.3 Stem cells and cancer Stem cells and cancer cells share...

Ngày tải lên: 12/09/2015, 21:26

... stress in mouse neural stem cells J Neurochem (In revision) Conference Abstracts: J Fu, S S W Tay, E A Ling, S T Dheen (2004) Analysis of proliferation and differentiation of neural stem cells in a ... stress and alters expression of genes involved in proliferation and cell fate specification of embryonic neural stem cells Society for Neuroscience 35th Annual Meeting, Abstract Number 24.10 (24 Neural ... Neural Stem Cells in Brain Injury and Disease, Theme A, A10), 12-16 November, Washington, DC, USA J Fu, S S W Tay, E A Ling, S T Dheen (2005) Abnormal proliferation and differentiation of neural stem...

Ngày tải lên: 30/09/2015, 06:36

...   1.1   Stem cells   1.1.1   Human pluripotent stem cells   1.1.2   In vitro differentiation potential of human pluripotent and neural stem cells   1.2   Candidate ... Introduction 1.1 Stem cells Stem cells have the remarkable potential to differentiate into specialized cells and thereby are key factors for the development of the whole organism All types of stem cells ... Reynolds and Weiss, 1992; Urbach et al., 2004) Neural stem cells of this process can give rise to neurons and glia, the two lineages most cells of the central nervous system belong to, and are...

Ngày tải lên: 26/11/2015, 09:54

... Section Neural Stem Cells as Progenitor Cells Chapter Systems for ex-vivo Isolation and Culturing of Neural Stem Cells Simona Casarosa, Jacopo Zasso and Luciano Conti Chapter Neural Stem Cell ... endothelial cells express the Notch ligand Jagged1 and can active neural stem cells regulating maintenance and proliferation both in vitro and in vivo thus implying that activated neural stem cells ... Cavalieri-Ottolenghi (NICO) Section Neural Stem Cells as Progenitor Cells Chapter Systems for ex-vivo Isolation and Culturing of Neural Stem Cells Simona Casarosa, Jacopo Zasso and Luciano Conti Additional...

Ngày tải lên: 08/03/2014, 19:20

... 199 Liposome Methods and Protocols, edited by Subhash C Basu and Manju Basu, 2002 198 Neural Stem Cells: Methods and Protocols, edited by Tanja Zigova, Juan R Sanchez-Ramos, and Paul R Sanberg, ... Studying Stem Cells and Progenitors Jane E Aubin, Fina Liu, and G Antonio Candeliere 403 30 Nonradioactive Labeling and Detection of mRNAs Hybridized onto Nucleic Acid cDNA Arrays Thorsten Hoevel and ... (ES cells to inject and cells to pellet for DNA) into the microfuge and spin for at 110g To make sure trypsin is removed, aspirate the supernatant and add mL M2 to the cells for injection and...

Ngày tải lên: 08/04/2014, 12:51

... of stem cells in repair of liver injuries Several types of stem cells, such as embryonic stem (ES) cells, induced pluripotent stem (iPS) cells, haematopoietic stem cells, and mesenchymal stem cells, ... liver stem/ progenitor cells exist in normal adult liver Recently, we and others have successfully identied oval cells and adult liver stem/ progenitor cells Here, we describe the identication and ... formation from stem cells; (4) Liver stem cells and hepatocarcinogenesis; and (5) Application of liver stem cells for cell therapy All these current topics shed light on stem cell technology...

Ngày tải lên: 29/05/2014, 17:06

... group in the identification, and characterization of potential sources of adult stem cells [7,10,1215], the aim of this study was to isolate, expand, characterize and assess the differentiation ... of the in vivo identity of mesenchymal stem cells Stem Cells 2008, 26:2287-2299 Krampera M, Marconi S, Pasini A, Galiè M, Rigotti G, Mosna F, Tinelli M, Lovato L, Anghileri E, Andreini A, Pizzolo ... cultures) A): Cells cultured for three days after initial plating Cells with an MSC-like phenotype and a small cluster of cells with endothelial appearance (arrows) (100×) B): Cells cultured...

Ngày tải lên: 18/06/2014, 15:20

... stem cells These include very small embryonic/epiblast like stem cells, multipotent dental stem cells, pluripotent stem cells from testis and amniotic fluid stem cells In the book Embryonic Stem ... Dental Stem Cells: An Alternative Adult Derived Stem Cell Source for Regenerative Medicine 451 Tammy Laberge and Herman S Cheung Chapter 24 Pluripotent Stem Cells from Testis Sandeep Goel and Hiroshi ... tremendous variety of approaches and techniques, and this book, Embryonic Stem Cells - Differentiation and Pluripotent Alternatives and its companion, Embryonic Stem Cells - Basic Biology to Bioengineering,...

Ngày tải lên: 27/06/2014, 19:20

... stem cells These include very small embryonic/epiblast like stem cells, multipotent dental stem cells, pluripotent stem cells from testis and amniotic fluid stem cells In the book Embryonic Stem ... Dental Stem Cells: An Alternative Adult Derived Stem Cell Source for Regenerative Medicine 451 Tammy Laberge and Herman S Cheung Chapter 24 Pluripotent Stem Cells from Testis Sandeep Goel and Hiroshi ... tremendous variety of approaches and techniques, and this book, Embryonic Stem Cells - Differentiation and Pluripotent Alternatives and its companion, Embryonic Stem Cells - Basic Biology to Bioengineering,...

Ngày tải lên: 28/06/2014, 04:20

... Mouse and human expression of shared molecules between inflammation and stem cells Mouse and human expression of shared molecules between inflammation and stem cells Comparison of mouse and human ... and2 inflammatory cells Inflammatory receptors and mediators shared between stem Inflammatory receptors and mediators shared between stem cells and inflammatory cells List of inflammatory receptors and mediators ... trafficking and 3) inflammatory cytokines produced by hematopoietic stem cells homing and retention in the bone marrow niche [18,19] Likewise, c-kit, the receptor for stem cell factor (SCF) and a known...

Ngày tải lên: 08/08/2014, 21:20