adjuvant therapy for lung cancer in the elderly
Báo cáo khoa học: "Target splitting in radiation therapy for lung cancer: further developments and exemplary treatment plans" pps
... With ongoing practice some 'rules' evolved, breaking some former "taboos" in radiotherapy of lung cancer: Minimizing the dose to the ipsilateral (i.e tumor bearing) lung In many cases the ipsilateral ... up in vacuum cradles, usually supine with the hands above the head A planning CT in treatment position is performed as 'slow CT' from the apex to the bases of the lung, patients freely breathing ... taken into account by a pencil beam algorithm Dose constraints for the spinal cord were set at 45 Gy, V20 (volume receiving >20 Gy) for a single lung at 50%, V25 for both lungs considered as a single...
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Screening for Cognitive Impairment in the Elderly pot
... of acetyl choline Tacrine (tetrahydroaminoacridine), has been approved for use in the United States and is available in Canada Modest but definite improvements in cognitive performance have been ... Screening for Cognitive Impairment in the Elderly Prepared by Christopher Patterson, MD, FRCPC1 Cognitive impairment is a common finding in older people, as the prevalence of dementia increases ... brain deficits in the elderly J Am Geriatr Soc 1975; 23: 433-441 Shulman K, Shedletsky R, Silver IL: The challenge of time: clock drawing and cognitive functioning in the elderly Int J Geriatr...
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Attitudes, barriers and facilitators for health promotion in the elderly in primary care doc
... Discussion Main findings Among the participating GPs, definitions of health promotion interventions in the elderly widely varied The opinion regarding the effectiveness of health promotion in the elderly ... well as regarding the content of the programme Providing information over the internet for instance, may not reach a substantial proportion of the target group To increase the interest for health ... health promotion in the elderly K Interface problems in health promotion in the elderly L Other important aspects Coding system: Categories for the coding process, used with the ATLAS.ti software...
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Báo cáo y học: "Prolonged high-dose intravenous magnesium therapy for severe tetanus in the intensive care unit: a case series" pot
... continue for a long time without obvious adverse effects or major organ toxicity is, in our opinion, the most interesting finding in our report Therefore, we believe that this report is a meaningful ... and safety are needed before Mg therapy can be accepted as the first-line therapy for tetanus Consent Written informed consent was obtained from our patients for publication of this case series ... Most reports on intravenous Mg therapy for tetanus come from developing countries such as Sri Lanka [11] and Vietnam [14] In most published cases, intravenous Mg therapy was used in an attempt...
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IDENTIFICATION, KINETIC AND STRUCTURAL CHARACTERIZATION OF SMALL MOLECULE INHIBITORS OF ALDEHYDE DEHYDROGENASE 3A1 (ALDH3A1) AS AN ADJUVANT THERAPY FOR REVERSING CANCER CHEMO-RESISTANCE
... standard deviation of the control reaction, δn= standard deviation of the inhibition reaction, µp= average of the points in the control reaction and µn=average of the points in the inhibition reaction ... 1.5 mM) and varied inhibitor concentrations In all cases including the control reactions lacking inhibitors, the final reaction mixture contained 2% (v/ v) DMSO The reaction was initiated by addition ... mustard forms intrastrand and interstrand cross–links between guanine bases from DNA 23 B Hypothesis and approaches Hypothesis Since ALDH3A1 is involved in metabolism of aldophosphamide (activated form...
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Health services research on endoscopic surveillance for gastric cancer in the singapore chinese population experience of the gastric cancer epidemiology clinical and genetic program
... Gastric cancer mortality Following the downward trend seen in incidence, GC mortality has also declined over time globally The declining mortality has been attributed to the declining incidence as there ... development, intuitively, eradicating this infection would eliminate cancer risk before precancerous lesions develop Therefore, screening for H pylori and treating those with a positive finding is ... with adjuvant and neoadjuvant chemotherapy plays an important role These drugs are effective in shrinking the tumor mass for better surgical outcome, decreasing the chance of recurrence, prolonging...
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Báo cáo khoa học: "Conformal radiotherapy for lung cancer: interobservers'''' variability in the definition of gross tumor volume between radiologists and radiotherapists" pot
... taking into account the difficulties in delineating the macroscopic volume of the target and its microscopic involvement [5,13-15] Delineation is generally performed in many centers by radiotherapists ... and the value of Pearson's correlation coefficients therapies, new planning strategies, including conformal radiotherapy and dose increase, are under investigation [25-29] in thoracic radiotherapy ... be responsible for this finding, such as integration between radiotherapy and diagnostic imaging departments Competing interests The authors declare that they have no competing interests Authors'...
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Bóa cáo y học: "Could CT screening for lung cancer ever be cost effective in the United Kingdom" pot
... £12,186 The two changes combined produce a 15 per cent fall in the baseline ICER, to £11,764 Other things remaining equal, the cost effectiveness of screening increases as the prevalence of cancer in ... Journal of Cancer 2005, 92:1959-1970 The Information Centre for Health and Social Care: National lung cancer audit: key findings about the quality of care for people with lung cancer in England incorporating ... by definition Second, attending for screening inevitably entails the incurring of time and travel costs on the part of those being invited These costs can be sizeable: in a trial of clinic-based...
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Tài liệu Vaccines for preventing influenza in the elderly (Review) docx
... and deaths from in uenza Description of the intervention Vaccines have been the main global weapon to minimise the impact of in uenza in the elderly for the last four decades In the year 2000, ... interest in influenza vaccines and Vaccines for preventing in uenza in the elderly (Review) Copyright © 2010 The Cochrane Collaboration Published by John Wiley & Sons, Ltd their performance How the intervention ... good coverage in those who most need it or the diluting effect on vaccines for in uenza of other agents circulating in the community (causing ILI, clinically indistinguishable from in uenza), might...
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RECOMMENDATIONS FOR BEST PRACTICES in the Management of Elderly Disaster Victims doc
... advocate for getting evacuees the services they require They also need to keep evacuees informed about the progress being made in resolving their problems This process should continue even when the ... living The plan for the administration of the SWiFT tool was to pair social workers with either a doctor or nurse Each of these pairings walked among the cots on the Astrodome floor looking for ... evacuation to the RAC The trauma resulting from the disaster, the process of evacuation, the disruption of regular care, and the stress of residing in the shelter complex further increased their vulnerability...
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báo cáo hóa học:" Development of targeted therapy for ovarian cancer mediated by a plasmid expressing diphtheria toxin under the control of H19 regulatory sequences" doc
... DTA expression in the ovarian cancer cell lines that led to cell death Therefore, we further investigated the therapeutic potential of the toxin vector in vivo using the ES-2 cell line which has ... from the lysed cells is not able to enter neighboring cells in the absence of the DT-B fragment [29] In order to determine the feasibility of this approach for the therapy of ovarian cancer in ... sequences for targeted gene therapy in cancer Int J Cancer 2001, 98:645-650 Maxwell IH, Glode LM, Maxwell F: Expression of diphtheria toxin A-chain in mature B-cells: a potential approach to therapy...
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Báo cáo hóa học: " Development of targeted therapy for bladder cancer mediated by a double promoter plasmid expressing diphtheria toxin under the control of H19 and IGF2-P4 regulatory sequences" potx
... protein Therefore the reduction in luciferase activity, reflect the inhibition of protein synthesis activity by the DTA In vivo targeted therapy animal models All surgical procedures and the care ... sequence Therefore, we further investigated the combination use of H19 and IGF2 regulatory sequences for driving toxin gene expression in therapeutic vectors for bladder cancer treatment The double ... transfection of principally the tumor urothelium In the same way an orthotopic model can be designed, which the bladder can then be easily approached by catheter In cancer gene therapy, direct DNA injection...
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báo cáo khoa học: "Vaginal treatment of endometrial cancer: role in the elderly" doc
... Nevertheless, these procedures could be often severely contra-indicated in endometrial cancer patient, since they require a general anesthesia, which is contra-indicated in endometrial cancer ... morbidities These results show how vaginal approach had a similar outcome in selected patients We compared the clinical outcome of the vaginal versus the abdominal hysterectomy in a population of elderly ... include vaginal hysterectomy with vaginal bilateral salpingo-oophorectomy, first line radiation therapy and endocrine therapies [10,11] Laparoscopic surgery is been progressively integrated into...
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Báo cáo khoa học: "Proposing the lymphatic target volume for elective radiation therapy for pancreatic cancer: a pooled analysis of clinical evidence" ppsx
... therapeutic modalities in adjuvant setting remain a focus of debate Radiation therapy is commonly used in adjuvant treatment for pancreatic cancer after radical surgery in the United States The effect of ... fashion, to investigate the efficacy of elective radiation therapy to the regional lymph nodes in adjuvant or definitive treatment using precision radiation therapy However, such effort is further complicated ... Lenzi R, Lahoti S, Vauthey JN, Janjan NA: Combining gemcitabine with radiation in pancreatic cancer: Understanding important variables influencing the therapeutic index Semin Oncol 2001, 28(3 Suppl...
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Báo cáo khoa học: "High-dose rate brachytherapy (HDRB) for primary or recurrent cancer in the vagina" docx
... Discussion Radiotherapy is the main therapeutic modality in the management of primary or recurrent vaginal cancer Brachytherapy remains integral part of definitive radiation therapy for these patients ... findings and imaging were also taken for reference for defining the target volume The median number of needles used were 14 (range 7–18) The dose of interstitial brachytherapy was 18.75 Gy in ... brachytherapy planning was performed and the dose was prescribed to clinical target volume defined based on clinical and imaging findings at the time of implantation(Figure 1) Pretreatment clinical...
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báo cáo khoa học: "EGFR and COX-2 protein expression in non-small cell lung cancer and the correlation with clinical features" pptx
... chemotherapy and thoracic radiotherapy and 22 patients had chemotherapy alone Immunohistochemistry (IHC) The paraffin embedded tumor specimens were cut into 4-um sections for IHC staining against ... cells, indicating that EGFR pathway involves in lung cancer development [28] Therefore, the detection of Figure Survival curves with different level of EGFR protein expression The solid blue line indicates ... trends in epidermal growth factor receptor targeting in cancer J Clin Oncol 2005, 23:2445-2459 13 Gschwind A, Fischer OM, Ullrich A: The discovery of receptor tyrosine kinases: targets for cancer therapy...
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báo cáo khoa học: " Correction: EGFR and COX-2 protein expression in non-small cell lung cancer and the correlation with clinical features" pps
... Paracancerous tissue 14.3 P < 0.05 Reference Li Feng, Liu Yongmei, Chen Huijiao, Liao Dianying, Shen Yali, Xu Feng, Wang Jin: EGFR and COX-2 protein expression in non-small cell lung cancer and the ... West China Hospital, Sichuan University, PR China 2Department of Pathology, West China Hospital, Sichuan University, PR China Table (corrected table five) COX-2 expression in tumor and paracancerous ... EGFR and COX-2 protein expression in non-small cell lung cancer and the correlation with clinical features Journal of Experimental & Clinical Cancer Research 2011 30:32 ...
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báo cáo khoa học: "Sustained complete remission of human epidermal growth factor receptor 2-positive metastatic breast cancer in the liver during long-term trastuzumab (Herceptin) maintenance therapy in a woman: a case report" docx
... chemotherapy in August 2001, radiation therapy was administered to the right breast In January 2002, after CT, the patient presented with a single metastatic lesion (diameter, 1.4 cm) in the right ... define a time point beyond which trastuzumab might not offer additional benefit Furthermore, evidence in the literature supports the idea that continuing anticancer treatments as maintenance therapy ... HER2-positive MBC while receiving trastuzumab maintenance therapy [9,10] The duration of remission in these cases ranges from four months to eight years, and in all cases, maintenance therapy was based on...
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Báo cáo y học: "Endoscopic therapy using an endoscopic variceal ligation for minute cancer of the esophagogastric junction complicated with esophageal varices: a case report" ppt
... full specimen for histological examination and for the diagnosis of the extent and infiltration depth of the lesion The outcome of endoscopic therapy can therefore be evaluated on the basis of ... markings were contained in the ligated band, resection was not performed for the lesion EVL was successively done for the esophageal varices in three places All EVL bands were placed in the esophagus ... junction (B) The middle esophagus The iatrogenic ulcers in the esophagus and EGJ resulting from the EVL were treated with the administration of a proton pump inhibitor and sodium alginate The ulcers...
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Báo cáo y học: "Squamous cell carcinoma of the nipple following radiation therapy for ductal carcinoma in situ: a case report" ppt
... radiation therapy) Radiation therapy has also been described as a risk factor for SCC In a report from the Childhood Cancer Sur- Figure p63 immunostaining of SCC Page of vivor study, radiation therapy ... during radiation therapy for breast cancer influence the risk of second malignancies These include quality, total dose, fractionation, degree of overlap between the fields, tissue volume in the ... fold-increase in risk for NMSC (SCC and basal cell carcinoma) Of these cancers 90% occurred within the radiation field [10] The association between radiation and NMSC is also prevalent in the...
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Tìm thêm: hệ việt nam nhật bản và sức hấp dẫn của tiếng nhật tại việt nam xác định các nguyên tắc biên soạn khảo sát các chuẩn giảng dạy tiếng nhật từ góc độ lí thuyết và thực tiễn khảo sát chương trình đào tạo của các đơn vị đào tạo tại nhật bản xác định thời lượng học về mặt lí thuyết và thực tế điều tra đối với đối tượng giảng viên và đối tượng quản lí khảo sát thực tế giảng dạy tiếng nhật không chuyên ngữ tại việt nam khảo sát các chương trình đào tạo theo những bộ giáo trình tiêu biểu nội dung cụ thể cho từng kĩ năng ở từng cấp độ xác định mức độ đáp ứng về văn hoá và chuyên môn trong ct mở máy động cơ lồng sóc các đặc tính của động cơ điện không đồng bộ đặc tuyến mômen quay m fi p2 đặc tuyến tốc độ rôto n fi p2 đặc tuyến dòng điện stato i1 fi p2 động cơ điện không đồng bộ một pha thông tin liên lạc và các dịch vụ phần 3 giới thiệu nguyên liệu từ bảng 3 1 ta thấy ngoài hai thành phần chủ yếu và chiếm tỷ lệ cao nhất là tinh bột và cacbonhydrat trong hạt gạo tẻ còn chứa đường cellulose hemicellulose chỉ tiêu chất lượng 9 tr 25