40 human infections and cancer emerging concepts and causality considerations
Báo cáo y học: " Induction of multiple matrix metalloproteinases in human dermal and synovial fibroblasts by Staphylococcus aureus: implications in the pathogenesis of septic arthritis and other soft tissue infections" pdf
... osteoarticular infections in 406 children with clinically suspected osteoarticular infections, 74 (18%) had a positive bacterial culture: 38 cases of SA and 36 cases of bone infections (osteitis and osteomyelitis), ... virulence factors during S aureus infections Calander and colleagues [29], using wild-type S aureus strain 8325-4 and its mutants lacking aureolysin, serine protease, and cysteine protease, demonstrated ... Previous studies by Wang and colleagues [31] have shown that inhibitors of p38 MAPK (SB202190) and ERK1/2 (PD98059) and inhibitors of Src Tyrosine kinase (PP2) and PI3-K (LY2 9400 2) effectively blocked...
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Báo cáo y học: "JNK suppression is essential for 17b-Estradiol inhibits prostaglandin E2-Induced uPA and MMP9 expressions and cell migration in human LoVo colon cancer cells" ppsx
... tPA and MMP-2 B The Effects of Prostaglandin E2 on the Expression of PAI1 and TIMPs in Human LoVo Colon Cancer Cells uPA and tPA is closely controlled by PAI-1 In addition, activation of MMP-2 and ... anti -cancer by inhibiting PGE2-induced migration in human LoVo cancer cells Materials and Methods Cells, Antibodies, Reagents and Enzymes Human colon cancer cell lines, LoVo, were obtained from the ... and MMP-9 in human LoVo colon cancer cells LoVo cells cultured in DMEM were treated with PGE2 (10-6M) for h, h, 12 h and 24 h, and subsequently observed protein level of uPA, tPA (A), MMP-2 and...
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báo cáo khoa học: "The effects of β-glucan on human immune and cancer cells" pptx
... here the literature and our experience on the in vitro and in vivo animal biological studies of β-glucans, particularly on their immune and anti -cancer mechanisms Physical and chemical properties ... essential if we want to understand and compare the results on how β-glucans act on our immune system and exerting anti -cancer effects A possibly well-defined β-glucan standard is urgently needed in ... MD-fraction aid cancer patients"? Altern Med Rev 2002, 7(6):451 Fisher M, Yang LX: Anticancer effects and mechanisms of polysaccharide-K (PSK): implications of cancer immunotherapy Anticancer Res...
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báo cáo khoa học: " Using transcriptomics to identify and validate novel biomarkers of human skeletal muscle cancer cachexia" pdf
... from cancer cachexia patients, including study of the UPP and autophagy systems, we sought to carry out both targeted and global molecular profiling in the skeletal muscle of cancer patients and ... Clinical data for patients and control subjects from centers and Table Demographics of controls and cancer patients included in the Affymetrix analysis from centre Center no -cancer (n = 7) Center ... sclerosis and ageing have demonstrated both increased and decreased expres sion of MuRF1 and MAFBx [52-56] This would suggest that the ubiquitin E3 ligases not play the same role in human cancer...
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Báo cáo y học: " An RNA replication-center assay for high content image-based quantifications of human rhinovirus and coxsackievirus infections" pps
... serotypes HRV1A and HRV2 (Fig 6A) HRV1A and HRV2 infections were dependent on the temperature and inoculum dose, as indicated by analyses at and h pi (Fig 6B, C) In addition, both infections were ... replication centers is time, dose and temperature dependent and correlates with emergence of infectious titres (A, B) The time and dose dependencies of HRV16 and CVB3 infections at 33.5°C (blue) or ... time course and titration experiments with HRV1A, 2, 14, 16 and 37 and CVB3 and B4 As expected from the initial experiments (see Fig 1B, D), the dsRNA infection assay scored a timeand dose-dependent...
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Báo cáo y học: "Human toxoplasmosis and the role of veterinary clinicians"
... opportunistic infections among persons infected with the human immunodeficiency virus Clin Infect Dis.1994;18:14-24 Han K, Shin DW, Lee TY, et al Seroprevalence of Toxoplasma gondii infection and risk ... women in Korea J Parasitol 2008; 94: 963-965 Grant S and Olsen CW Preventing zoonotic diseases in immunocompromised persons: the role of physicians and veterinarians Emerg Infect Dis 1999; 5: 159-163...
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Human rationality and artificial intelligence
... tasks which human beings can only carry out by exercising their powers of understanding and reason Thus, for example, playing chess is an intellectually demanding task for human beings and we regard ... Problems?’, in Manktelow and Over (eds.), Rationality, ch For a fuller account and a defence of the mental models approach, see JohnsonLaird and Byrne, Deduction Human rationality and artificial intelligence ... Myles Brand and Robert M Harnish (eds.), The Representation of Knowledge and Belief (Tucson: University of Arizona Press, 1986) See also my ‘Rationality, Deduction and Mental Models’ Human rationality...
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The Modern Human colonisation and the Neanderthal extinction
... and 17 ◦ C, m between −1 and ◦ C and M between and 14 ◦ C; (3) supra-Mediterranean, characterised by T between and 13 ◦ C, m between −4 and −1 ◦ C and M between and ◦ C; and (4) Euro-Siberian characterised ... margins and the presence of lakes during mild 160 Neanderthals and Modern Humans oceanic phases would have opened up opportunities for ecotonal human ecotypes and reduced them for plains human ... Moderns and Neanderthals would have been within the same geographical area for over 60 thousand years (Tchernov, 1992, 1998; Bar-Yosef, 1994, 1998) and in other Modern Human colonisation and Neanderthal...
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The revolution in philosophy (I) - human spontaneity and the natural order
... “representation” and “intuition” have become the standard way of translating Kant’s terms, so I shall stick with that here Critique of Pure Reason, = and = (I): Human spontaneity and the ... the basic concepts of metaphysics (such as those of God and the soul, and extending to notions like causality) were of non-sensible objects or forms that “transcended” experience; and that the ... philosophy (about the status of necessary and contingent truths and what can be taken for granted) See Guyer, Kant and the Claims of Knowledge (I): Human spontaneity and the natural order being true...
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The return of universalist law - human rights and free trade
... sorrow to mankind, and to reaffirm faith in fundamental human rights, in the dignity and worth of the human person, in the equal rights of men and women and of nations large and small, and to establish ... expanded the earlier 1947 GATT That Preamble refers to ‘raising standards of living, ensuring full employment and a large and steadily growing volume of real income and effective demand’, expanding ... existence and in the human lives which might fall into one’s ‘care and disposal’.97 Logical and political calculations appear ill suited to the task of upholding human rights Universal human rights...
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Tài liệu To establish an Office on Women’s Health within the Department of Health and Human Services, and for other purposes pdf
... Health and 25 Human Services offices, agencies, and regional ac- 26 tivities regarding women’s health and stimulate ac•HR 1784 IH tivities and facilitate coordination of such depart- mental and ... of women— 15 ‘‘(1) establish short-range and long-range goals 16 and objectives and coordinate all activities within the 17 Department of Health and Human Services that re- 18 late to disease ... recipients of grants, con- tracts, and agreements under subsection (c), and be- tween the Office and health professionals and the general public 10 ‘‘(c) GRANTS 11 AND CONTRACTS REGARDING DU- TIES.—...
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Tài liệu NTP-CERHR Monograph on the Potential Human Reproductive and Developmental Effects of Di-Isodecyl Phthalate (DIDP) pdf
... 12–23, 33–68, 114–225, and 233– 453 mg/kg bw/day for males and 14–21, 40 58, 139–202, and 274 406 mg/kg bw/day for females Doses received by females during the gestation and lactation periods ... for 10 weeks prior to mating and throughout gestation and lactation (35) Hepatic hypertrophy and eosinophilia were observed in F1 and F2 male and female pups in the midand high-dose groups Postnatal ... (females on pnd 14 and males on pnd 35) and 0.4% dose group (females on pnd 14 and 21, and males on pnd 14, 28, and 35) Hormonally-mediated endpoints such as anogenital distance and nipple retention...
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Tài liệu Báo cáo khoa học: Mixed lineage leukemia: roles in human malignancies and potential therapy pdf
... KLF4 and PBX1 directly regulate NANOG expression in human embryonic stem cells Stem Cells 27, 2114–2125 Rowland BD & Peeper DS (2006) KLF4, p21 and context-dependent opposing forces in cancer ... nuclear factor-kappaB, and glucose regulation Cancer Res 68, 6643–6651 Guo X, Ramirez A, Waddell DS, Li Z, Liu X & Wang XF (2008) Axin and GSK3- control Smad3 protein stability and modulate TGF-signaling ... damage and maintains self-renewal of leukaemia stem cells Nature 457, 51–56 ´ Seoane J, Le HV, Shen L, Anderson SA & Massague J (2004) Integration of Smad and forkhead pathways in Role of MLL in human...
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Tài liệu Báo cáo khoa học: Application of a fluorescent cobalamin analogue for analysis of the binding kinetics A study employing recombinant human transcobalamin and intrinsic factor pdf
... ligand was essentially enwrapped, and its solvent accessible surface decreased to % 7% with only the ribose moiety exposed In total, 34 hydrogen and hydrophobic contacts between TC and the ligand ... CBC and the full length IF (Fig 3A and Table 1) The time course of the binding between CBC and peptides is presented in Fig 3B,C The corresponding rate constants k+CBC and kCBC for IF20 and IF30 ... of IF, TC and HC for Cbl The probable scheme of interaction between IF, the ligand and the receptor is presented in 4750 Fig Schematic presentation of IF interaction with the ligands and the receptor...
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Scientific Committee on Enteric Infections and Foodborne Diseases pot
... Enterovirus is resistant to alcohol and phenolic disinfectants; Linen and Waste from patients suffering from HFMD should be handled with care, and wash hands after handling 7.5 Advice given to the ... Clinical features and risk factors of pulmonary oedema after enterovirus-71-related hand, foot, and mouth disease Lancet 1999;354:1682–86 Alexander Jp Jr, Baden L, Pallansch MA, Anderson LJ, Enterovirus ... B2, B5 and EV71 HFMD is sometimes confused with foot -and- mouth disease of cattle, sheep, and swine The latter is caused by a virus Aphthovirus which belong to the family of Picornaviridae .and will...
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HUMAN RIGHTS AND GENDER EQUALITY IN HEALTH SECTOR STRATEGIES pdf
... Declaration and Programme of Action affirmed that the human rights of women and girls are inalienable, integral and indivisible parts of universal human rights and that the equal status and human rights ... with, and promote, human rights standards and principles, including gender equality Identify gender equality and human rights-related gaps and opportunities with respect to national commitments and ... Declaration of Human Rights (UDHR) and other international human rights instruments Process: Human rights standards and principles guide all development cooperation and programming in all sectors and phases...
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