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2targeted therapy for a genetic model of colorectal cancer

Báo cáo hóa học:

Báo cáo hóa học: " Modulation of the major histocompatibility complex by neural stem cell-derived neurotrophic factors used for regenerative therapy in a rat model of stroke" ppt

Hóa học - Dầu khí

... of faults for the right and left forelimbs SOFFF and DOFFF were used as an index of motor deficit CSF aspiration 80 μL of CSF were aspirated from the cisterna magna of 40 chloral hydrate-sedated ... Statistical Analysis Results are expressed as mean ± standard deviation (SD) The non-parametric one-way ANOVA was applied to analyze continuous variables: the gene expression of NGF, BDNF and ... (B-ii), areas near the ventricular lining and vascular wall near the hippocampus (B-iv) of transplanted rats Scale bars: 75 μm Sun et al Journal of Translational Medicine 2010, 8:77 http://www.translational-medicine.com/content/8/1/77...
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Báo cáo sinh học:

Báo cáo sinh học: " Induction of Th1Immune responses following laser ablation in a murine model of colorectal liver metastase" potx

Hóa học - Dầu khí

... liver and tissue was collected at various time points post ablation as indicated Control mice had sham LA performed (LA probe was not activated), black bars = sham ablated liver, grey bars = ablated ... composition and activation status of the CD3+ T cell population after LA therapy and will validate their protective roles as their modulation may further enhance treatment outcomes Additional material Additional ... rectangle Panel e depicts a section of liver parenchyma from an LA treated animal immediately following ablation Panels f-l are CD3+ stained tumor sections from LA treated animals collected at day...
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báo cáo hóa học:

báo cáo hóa học:" Induction of Th1Immune responses following laser ablation in a murine model of colorectal liver metastases" pot

Hóa học - Dầu khí

... liver and tissue was collected at various time points post ablation as indicated Control mice had sham LA performed (LA probe was not activated), black bars = sham ablated liver, grey bars = ablated ... composition and activation status of the CD3+ T cell population after LA therapy and will validate their protective roles as their modulation may further enhance treatment outcomes Additional material Additional ... rectangle Panel e depicts a section of liver parenchyma from an LA treated animal immediately following ablation Panels f-l are CD3+ stained tumor sections from LA treated animals collected at day...
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Báo cáo sinh học:

Báo cáo sinh học: "Combination immunotherapy and active-specific tumor cell vaccination augments anti-cancer immunity in a mouse model of gastric cancer" pdf

Điện - Điện tử

... Michaeli D: A phase II study of G17DT in gastric carcinoma Eur J Surg Oncol 2004, 30:536-543 Sato Y, Fujiwara T, Mine T, Shomura H, Homma S, Maeda Y, Tokunaga N, Ikeda Y, Ishihara Y, Yamada A, Tanaka ... immunotherapy with radiation and CpG-based tumor vaccination for the eradication of radioand immuno-resistant lung carcinoma cells Cancer Sci 2009, 100:934-939 Dranoff G, Jaffee E, Lazenby A, Golumbek ... cell vaccination augments anti -cancer immunity in a mouse model of gastric cancer Journal of Translational Medicine 2011 9:140 Submit your next manuscript to BioMed Central and take full advantage...
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Báo cáo y học:

Báo cáo y học: "MALDI-TOF MS Combined With Magnetic Beads for Detecting Serum Protein Biomarkers and Establishment of Boosting Decision Tree Model for Diagnosis of Colorectal Cancer"

Y học thưởng thức

... Cancer sixth edition staging J Natl Cancer Inst.2004; 96(19):1420-5 Australian Institute of Health and Welfare (AIHW), Australasian Association of Cancer Registries (AACR) Cancer in Australia ... screening and surveillance Gastrointest Endosc.2006; 63:546-57 Karakosta A, Golias Ch, Charalabopoulos A, et al Genetic models of human cancer as a multistep process Paradigm models of colorectal cancer, ... volunteers was collected and analyzed A panel of differentially expressed proteins was advocated for biomarkers of diagnosis for colorectal cancer Materials and methods Patients Experiment was performed...
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Báo cáo khoa học:

Báo cáo khoa học: "A Part of Speech Estimation Method for Japanese Unknown Words using a Statistical Model of Morphology and Context" pptx

Báo cáo khoa học

... kanji katakana katakana-kanji kanji-hiragana hiragana kanji-katakana kat akana-symbol-katakana number kanji-hiragana-kanji alphabet kanji-hir agana-kanji-hir agana hiragana-kanji percent 45.1% 11.4% ... speech Table shows examples of common charto Chinese characters Hiragana and katakana are acter bigrams for each part of speech in the infresyllabaries: The former is used primarily for grammatical ... types of characters other t h a n punctuation marks: kanji, hiragana, katakana, R o m a n 3.4 P a r t o f S p e e c h a n d W o r d M o r p h o l o g y alphabet, and Arabic numeral Kanji which means...
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Báo cáo sinh học:

Báo cáo sinh học: "Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma" pptx

Hóa học - Dầu khí

... nick-end labeling; ALT: alanine transaminase; AST: aspartate aminotransferase; BUN: blood urea nitrogen; Cr: Creatinine Acknowledgements This work was supported by grants from the National Natural Science ... therapy of cancer: horseradish peroxidase/indole-3-acetic acid Cancer Gene Ther 2000, 7:1414-1420 Folkes LK, Candeias LP, Wardman P: Toward targeted “oxidation therapy of cancer: peroxidase-catalysed ... the treated animals to measure the biochemistry markers including alanine transaminase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN) and creatine (Cr) using commercial kits...
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báo cáo hóa học:

báo cáo hóa học:" Gene therapy with tumor-specific promoter mediated suicide gene plus IL-12 gene enhanced tumor inhibition and prolonged host survival in a murine model of Lewis lung carcinoma" doc

Hóa học - Dầu khí

... nick-end labeling; ALT: alanine transaminase; AST: aspartate aminotransferase; BUN: blood urea nitrogen; Cr: Creatinine Acknowledgements This work was supported by grants from the National Natural Science ... therapy of cancer: horseradish peroxidase/indole-3-acetic acid Cancer Gene Ther 2000, 7:1414-1420 Folkes LK, Candeias LP, Wardman P: Toward targeted “oxidation therapy of cancer: peroxidase-catalysed ... the treated animals to measure the biochemistry markers including alanine transaminase (ALT), aspartate aminotransferase (AST), blood urea nitrogen (BUN) and creatine (Cr) using commercial kits...
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báo cáo khoa học:

báo cáo khoa học: "A role of 18F-fluorodeoxyglucose positron emission/computed tomography in a strategy for abdominal wall metastasis of colorectal mucinous adenocarcinoma developed after laparoscopic surgery" pptx

Báo cáo khoa học

... Clinicopathological study of colorectal mucinous carcinoma in Taiwan: A multivariate study J Gastroenterol Hepatol 1996, 11:77-81 Nozoe T, Anai H, Nasu S, Sugimachi K: Clinicopathological characteristics ... disadvantages False-negative findings can occur for several reasons, including inflammation, small lesions size and diabetes Mucinous adenocarcinoma as a histological type, regardless of the organs, may ... publication of this case report and any accompanying image A copy of the written consent is available for review by the Editor-in Chief of this journal Abbreviations CRC: colorectal carcinoma; 18F-FDG...
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báo cáo khoa học:

báo cáo khoa học: " Comparison of Radioimmuno and Carbon Nanotube Field-Effect Transistor Assays for Measuring Insulin-Like Growth Factor-1 in a Preclinical Model of Human Breast Cancer" doc

Báo cáo khoa học

... a pattern of progressive adenocarcinoma with similar genetic changes and pathophysiology as seen in human breast cancers associated with BRCA1-mutations [11,12] Additionally, as in human BRCA1-associated ... University of Maryland, Baltimore animal facility and maintained in accordance with institutional guidelines approved by the University of Maryland, Baltimore Animal Care and Use Committee To compare ... this article as: Jones et al.: Comparison of Radioimmuno and Carbon Nanotube Field-Effect Transistor Assays for Measuring InsulinLike Growth Factor-1 in a Preclinical Model of Human Breast Cancer...
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Báo cáo y học:

Báo cáo y học: "The significance of glucose, insulin and potassium for immunology and oncology: a new model of immunity" ppt

Báo cáo khoa học

... 6(2): Dandona P, Aljada A, Chaudhuri A, Bandyopadhyay A: The potential influence of inflammation and insulin resistance on the pathogenesis and treatmentof atherosclerosis-related complications in ... the bacteria [65] In our model that is what happens when high doses of GIK are administered intravenously for a period of several hours Reactivated lymphocytes attack pathogens and release cytokines ... therefore suggest that hyperglycemia is the normal response of the body as it tries to make nutrients available for the repair of damaged tissues If, after a trauma or inflammation, systemic infection...
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Báo cáo y học:

Báo cáo y học: "External validation of a modified model of Acute Physiology and Chronic Health Evaluation (APACHE) II for orthotopic liver transplant patients" docx

Báo cáo khoa học

... Critical Care June 2002 Vol No Arabi et al There are several obvious advantages to the use of APACHE II as a model of severity of illness for liver transplant patients These include the familiarity ... mortality was again not calculated Angus et al [9] recently calculated the predicted mortality for postoperative liver transplantation patients and found that APACHE II system overestimated mortality ... resistance, an increase in cardiac output, a decrease in pH, an increase in lactate, an increase in potassium, and a prolongation of prothrombin time [16,17] Although some of these abnormalities...
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Báo cáo y học:

Báo cáo y học: " Local therapy with CpG motifs in a murine model of allergic airway inflammation in IFN-β knock-out mice" doc

Báo cáo khoa học

... bronchial inflammation and airway hyperreactivity in mice Pharmacology 1997, 55:32-43 Satoh Y, Kasama K, Kuwabara M, Yimin, Diao HY, Nakajima H, Kohanawa M, Minagawa T: Suppression of late asthmatic ... Echtenacher B, Hehlgans T, Mannel DN: Antimetastatic effect of CpG DNA mediated by type I IFN Cancer Res 2001, 61:5523-5528 Nakajima H, Nakao A, Watanabe Y, Yoshida S, Iwamoto I: IFN-alpha inhibits ... 30:1841-1850 Takabayashi K, Libet L, Chisholm D, Zubeldia J, Horner AA: Intranasal immunotherapy is more effective than intradermal immunotherapy for the induction of airway allergen tolerance in Th2-sensitized...
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Báo cáo y học:

Báo cáo y học: " A stochastic model of oncogene expression and the relevance of this model to cancer therapy" ppt

Báo cáo khoa học

... is a specific feature of Bcr-Abl positive disease or a manifestation of a more general principle of cellular transformation and cancer Namely, does an oncogene act in a similar fashion within a ... N particular cell population The mathematical relations that we have formulated can quantitatively determine how ablation of an oncogene's protein activity can result in apoptosis and/or a decrease ... theoretical calculations of survival fractions as a function of changes of oncogene expression, differentiation and the initial survival fraction before a targeted therapy is applied, demonstrating...
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Báo cáo y học:

Báo cáo y học: "Intrathecal siRNA against Toll-like receptor 4 reduces nociception in a rat model of neuropathic pain"

Y học thưởng thức

... sequence of rat TLR4 (GenBank accession NM_019178) were: 5’-CUACCAACAGAGAGGAUAU-3” (siRNA1), 5’-GUCUCAGAUAUCUAGAUCU-3’ (siRNA2), 5’-GAGCCGGAAAGUUAUUGUG-3’ (siRNA3) All siRNAs were chemically synthesized ... once daily for days, starting from day before CCI surgery Evaluation of tactile allodynia and thermal hyperalgesia The paw withdrawal latency (PWL) to radiant heat and paw withdrawal threshold ... spinal cord tissues Extracted RNA was pretreated with DNaseⅠ at 37 for 30 minutes before reverse transcription reaction was performed using a high capacity cDNA archived kit (TaKaRa, Japan) A Real-Time...
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Báo cáo y học:

Báo cáo y học: " WT1 PEPTIDE VACCINATION IN COMBINATION WITH IMATINIB THERAPY FOR A PATIENT WITH CML IN THE CHRONIC PHASE"

Y học thưởng thức

... M, Hirai M, Tominaga N, Nakajima H, Elisseeva OA, Masuda T, Nakano A, Kawakami M, Oji Y, Ikegame K, Hosen N, Udaka K, Yasukawa M, Ogawa H, Kawase I, Sugiyama H: Wilms tumor gene peptide-based ... 2000;95:2198-2203 Oka Y, Tsuboi A, Kawakami M, Elisseeva OA, Nakajima H, Udaka K, Kawase I, Oji Y, Sugiyama H: Development of WT1 peptide cancer vaccine against hematopoietic malignancies and solid cancers ... peptide vaccine and the resultant cancer regression Proc Natl Acad Sci U S A 2004;101:13885-13890 Kawakami M, Oka Y, Tsuboi A, Harada Y, Elisseeva OA, Furukawa Y, Tsukaguchi M, Shirakata T, Nishida...
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Tài liệu Báo cáo khoa học: Proteomic analysis of dopamine and a-synuclein interplay in a cellular model of Parkinson’s disease pathogenesis docx

Tài liệu Báo cáo khoa học: Proteomic analysis of dopamine and a-synuclein interplay in a cellular model of Parkinson’s disease pathogenesis docx

Báo cáo khoa học

... Pro transmission scanner (Epson, Nagano, Japan) and analyzed with imagemaster 2d platinum software, version 5.0 (GE Healthcare) Spots were detected automatically by the software and manually refined; ... Germany) Capillary voltage was 1.5–2 kV and a dry gas flow rate of 10 LÆmin)1 was used with a temperature of 230 °C The scan range was 300–1800 m ⁄ z The tandem mass spectra were annotated and peak list ... eukaryotic initiation factor 5A (eIF 5A) , parathymosin, L7 ⁄ L12, annexin A2 , annexin A5 , aldolase A, fascin and peroxyredoxin 1] displayed quantitative differences, regardless of whether or not a- synuclein...
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Tài liệu Báo cáo khoa học: A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana doc

Tài liệu Báo cáo khoa học: A kinetic model of the branch-point between the methionine and threonine biosynthesis pathways in Arabidopsis thaliana doc

Báo cáo khoa học

... 270) the aspartate-derived amino-acids pathway and aromatic amino-acids pathway in plant and in microorganisms are such that ux coordination could also be obtained The distribution of the carbon ... the ELISA assays We thank Pr Roland Douce and Dr Michel Matringe and Mickaela Homan for critical reading of the manuscript Special ă thanks to Maighread Gallagher for the correction of the English ... with KALEIDAGRAPH (Abelbeck Software, Reading, PA, USA) A series of constant or changing values were generated for the dierent input variables and the calculations were done using the appropriate...
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