2 test preparations under the microscope
contact dermatitis 5th ed - j. johansen, et al., (springer, 2011)
Ngày tải lên :
12/05/2014, 17:11
... sites The thigh has the highest reactivity and the palms the lowest reactivity [226] The skin on the volar forearm shows a graded susceptibility from the wrist to the cubital fossa, with the cubital ... suffered from the disease, whereas others did not He therefore posed the question: Can it be possible that some peculiar structure of the cuticule or rete mucosum constitutes the idiosyncrasy? The history ... with the fifth edition This has, of course, only been possible with the help of the many great contributors and the editors are very grateful to each and every one of them Last but not the least,...
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Women and Adverse Drug Reactions Reporting in the Canadian Context pot
Ngày tải lên :
22/03/2014, 11:20
... – the industry, on the one hand, and the consumer’s health movement, on the other, with government showing favour to both camps, depending on the political climate of the day Women in both the ... in the Health Products and Foods Branch to replace the Therapeutic Products Programme: the Therapeutic Products Directorate (TPD); the Biologics and Genetic Therapies Directorate (BGTD); and the ... provide the same services and more information about them On the important issue of information sharing, the report did not indicate when – or whether – it would implement the recommendations of the...
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Báo cáo y học: "Patch Testing in Non-Immediate Drug Eruptions" potx
Ngày tải lên :
08/08/2014, 21:20
... concerned, the ESCD suggests measuring the diameter of the papule, whereas the ENDA considers an infiltrate erythema as a positive reaction and suggests measuring the diameter of the reaction ... and the allergologic evaluation, the time of readings, and the scoring (see Table 1) In effect, the criteria of the International Contact Dermatitis Research Group are similar to those of the ... from the test site may have the same effect as low doses of systemic glucocorticoids.7 There are slight differences between the aforementioned guidelines regarding the time interval between the...
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R INTE S OF MEDIC REPORTING ADVERSE DRUG REACTIONS DEFINITIONS OF TERMS AND CRITERIA FOR THEIR USE ppt
Ngày tải lên :
07/03/2014, 10:20
... the data corrupted at source, by the careless use of words other than those that the patients use in talking to their physicians When, as reporters, we are using terms other than those that the ... of organs or tissues in the retroperitoneal space, compressing the ureters, the great vessels, the bile duct or other structures Basic requirements for use of the term The demonstration of fibrotic ... is the main advantage of this publication? The main advantage is the opportunity to reduce observational and linguistic biases in the assignment of terms Also, from the experience gained from the...
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Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) pdf
Ngày tải lên :
25/03/2014, 05:20
... dụng amiodaron (theo Reactions Weekly; Số 1022; 09/10/2004) Liệu pháp insulin làm tăng nguy ung th đại trực tràng (Hoa Kỳ) Nghiên cứu hồi cứu 24.918 bệnh nhân tiểu đờng týp 2, theo dõi thời gian ... amiodaron điều trị rung tâm nhĩ Bệnh nhân đến đơn vị cấp cứu; sau đợc chuẩn đoán rung nhanh tâm nhĩ kéo theo đau ngực thiếu máu cục tim, đợc bắt đầu truyền tĩnh mạch 300 mg amiodaron Sau phút, bệnh nhân ... lần tiêm adrenalin, hồi phục đợc tuần hoàn Điện tâm đồ cho thấp nhịp xoang, tần số 88/phút, kèm theo có lạc chỗ tâm thất tiêu điểm Tuần hoàn 92 bệnh nhân đợc củng cố truyền liên tục adrenalin...
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Phản ứng có hại của thuốc (Adverse Drug Reactions; ADR) docx
Ngày tải lên :
03/04/2014, 00:20
... thận trọng theo cách uống trên, uống muối sắt, tetracyclin khác, corticoid, muối lithi, thuốc chống viêm không steroid, alendronat v.v (Theo J.national cancer Jnit 95; số 13; 7/2003) (Theo Reactions ... Khuyến cáo thầy thuốc nên ý đến trờng hợp nghi ngờ phản ứng phản vệ thận trọng trớc gây mê (Theo Anesthesialogy: 99; số 3; 9/2003) 85 ... chứa nguyên tố vi lợng kẽm nguồn (32%) kèm ăn thịt bê (11%) ngũ cốc (5%) Trong số 587.440 ngời/năm theo dõi, có gặp 2.902 trờng hợp bị ung th tuyến tiền liệt Loại trừ yếu tố nguy khác, thấy số bổ...
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Báo cáo y học: " Parkinsonism caused by adverse drug reactions: a case series." pps
Ngày tải lên :
11/08/2014, 00:23
... dopamine in the dopaminergic systems, which may explain the remarkable effects of levodopa in these two cases The effects of general anaesthesia were for many years attributed to changes in the physical ... http://www.jmedicalcasereports.com/content/5/1/105 The mechanism by which inhalational general anesthesia acts on the brain is still unknown It has been assumed that the lipid solubility of these compounds alters the physicochemical ... condition, these may resolve after discontinuation of the offending drugs or administration of levodopa for persistent symptoms Further studies are warranted to elucidate the relationship and the mechanism...
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Tài liệu Women Sufficiently Represented in New Drug Testing, but FDA Oversight Needs Improvement doc
Ngày tải lên :
12/02/2014, 23:20
... reflected the prevalence of the disease in the total population but were not necessarily statistically sufficient to prove the safety or efficacy of the drug for either sex Despite the participation ... Guidance The language of the 1998 demographic regulation is less specific than the 1993 guidance The 1998 regulation has the force and effect of law, while the 1993 guidance does not legally bind either ... taking the drug), the total number of women participating in the treatment group for all of the pivotal trials, and the total number of women participating in the comparison group for all of the...
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Drug Testing in Alternate Biological Specimens pot
Ngày tải lên :
06/03/2014, 09:20
... sweat The chapters in this book focus on these less traditional specimens and particularly the application of these areas of practice to the drugs of abuse The use of these specimens enhances the ... scan is used to determine the position of the fetus A needle is inserted through the abdomen into the uterus where there is the least chance of touching the placenta or the fetus Although complications ... because these are the easiest to collect In addition, in the case of blood, or its components, it represents the dynamic state of drug distribution in the body with the best relation to the state...
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FDA Needs to Ensure More Study of Gender Differences~ in Prescription Drug Testing potx
Ngày tải lên :
28/03/2014, 12:20
... all the drugs in our survey, but for about 60 percent of the drugs, women were under- represented in the trials Our method of assessing whether women were underrepresented was to compare the proportion ... contraceptives Drug interactions with oral contraceptives can either decrease the effectiveness of the contraceptives or increase the toxicity of the other drug For example, many drugs, such as those used ... B-243898 most drugs, the representation of women reflected the gender distribution of the incidence of the corresponding disease in women The agency also believes that the level of female representation...
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báo cáo hóa học: " A review of methods used in assessing nonserious adverse drug events in observational studies among type 2 diabetes mellitus patients" docx
Ngày tải lên :
20/06/2014, 15:20
... administrative data exceeded the requirements of the guidelines for pre-approval safety assessment, whereas this was the case in less than a quarter of the studies using any of the other specified methods ... The Netherlands 2Graduate School of Medical Sciences, University of Groningen, Groningen, The Netherlands 13 14 15 Authors’ contributions LH conducted the literature search, participated in the ... participate in the literature search, data analysis or interpretation of the results There are no conflicts of interest The authors thank Truus van Ittersum for her assistance with the literature...
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Báo cáo y học: "Could chiropractors screen for adverse drug events in the community" potx
Ngày tải lên :
13/08/2014, 14:20
... that the chiropractor either send the patient back to the prescribing [clinician] with informative questions or contact the prescribing [clinician] to discuss the individual patient’ [46] The ... adverse drug event may be reported by the consumer, their pharmacist, and their physician or other healthcare provider Consumers who think that they or someone in their family has experienced a serious ... to report to the FDA If their health care provider chooses not to fill out the FDA Voluntary Adverse Event Report, or if the consumer does not wish to have the form filled out by the health care...
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Introduction to Financial Econometrics Hypothesis Testing in the Market Model
Ngày tải lên :
13/12/2013, 14:53
... so-called F-test The idea behind the F-test is to estimate the model imposing the restrictions specified under the null hypothesis and compare the fit of the restricted model to the fit of the model with ... on the null hypothesis α = whereas if it is less than the data are in support of the null hypothesis1 To determine how big | tα=0 | needs to be to reject the null, we use the fact that under the ... Hypotheses about β In the market model regression β measures the contribution of an asset to the variability of the market index portfolio One hypothesis of interest is to test if the asset has the...
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Tài liệu Color Atlas of Pharmacology (Part 8): Adverse Drug Effects pptx
Ngày tải lên :
26/01/2014, 19:20
... antibodies of the IgE type combine via their Fc moiety with receptors on the surface of mast cells Binding of the drug provides the stimulus for the release of histamine and other mediators In the most ... communicate to the patient whether or not they are concerned about the patient’s problem, or certain about the diagnosis and about the value of prescribed therapeutic measures In the care of a ... In the individual case, it may be impossible to decide whether therapeutic success is attributable to the drug or to the therapeutic situation What is therefore required is a comparison of the...
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Tài liệu Pragmatic Unit Testing in C# with NUnit pptx
Ngày tải lên :
16/02/2014, 13:20
... expand the project’s node in the Solution Explorer, bring up the context menu on the References folder, then select “Add Reference ” Once there, browse to the nunit.framework.dll from the NUnit ... sometime call this the “Whac-a-Mole” effect In the carnival game of Whac-a-Mole, the player must strike the mechanical mole heads that pop up on the playing field But they don’t keep their heads up ... fragment in the book is printed in the margin next to the code fragment itself Some code fragments evolve with the discussion, so you may find the same source code file (with the same name) in the main...
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Pragmatic Unit Testing in Java with JUnit potx
Ngày tải lên :
15/03/2014, 10:20
... write the test code itself, either before or concurrently with the implementation code Next, you run the test itself, and probably all the other tests in that part of the system, or even the entire ... fragment in the book is printed in the margin next to the code fragment itself Some code fragments evolve with the discussion, so you may find the same source code file (with the same name) in the main ... sometime call this the “Whac-a-Mole” effect In the carnival game of Whac-a-Mole, the player must strike the mechanical mole heads that pop up on the playing field But they don’t keep their heads up...
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Testing in Scala potx
Ngày tải lên :
24/03/2014, 01:21
... performed on the nouns provided in the Given clause Finally, Then specifies the results of the test, where all post-action analysis takes place The silent partner in the GivenWhenThen trait is the and ... referenced by the garthBrooks variable, and also by the chrisGaines variable The third line asserts that the object the garthBrooks variable is referencing is the same object The last two lines of the ... the assertions In AlbumTest, the ShouldMatchers trait was used to form the assertion: album.artist.firstName should be ("Michael") Note the should verb in the statement The lefthand side of the...
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Pulmonary rehabilitation in multi-drug resistant tuberculosis (TB MDR): a case report potx
Ngày tải lên :
29/03/2014, 03:20
... improvement in the perception of the dyspnea measured with the MRC scale from to (4: Very severe; 1: mild) and with the Borg scale from to The need for oxygen was reevaluated at the end of the rehabilitation ... performed in the morning, and the one with the greatest distance in meters was registered Oxygen flow was adjusted to keep SpO2 at/over 90% At the beginning and end of the rehabilitation, the chronic ... dyspnea, as well as tips for the treatment and prevention of exacerbations The quality of life was evaluated at the beginning and at the end of the training program through the SF-36 v.2 Health Questionnaire,...
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Báo cáo Y học: Barrier passage and protein dynamics in enzymatically catalyzed reactions docx
Ngày tải lên :
31/03/2014, 23:20
... complexation lowers the pKa of the alcohol proton and causes the formation of the alcoholate The chemical step is then transfer of a hydride from the alkoxide to the NAD+ cofactor They [46] have found ... antisymmetric because of the mathematical property of the functional form of the coupling on reflection about the origin This property has deeper implications than the mathematical nature of the symmetry ... strong peak in the spectral density along the line connecting the alcoholate and the NAD+ should be found close to the actual frequency of the promoting vibration We then calculated the force or...
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