... trying for a baby, as medical care for highrisk pregnancies was improving dramatically Following discussion with the Transplantation Unit and the high- risk pregnancy specialists, the IVF unit ... immunosuppressive or antihypertensive (blood pressure) medication required Risks to the mother, the fetus and the neonate Severe pre-eclampsia and eclampsia can result in irreversible damage to the maternal kidney, ... associated with severe growth retardation of the fetus, and often, premature delivery A case of highrisk pregnancy A 34-year-old woman (Mrs A) was referred to an IVF unit following eight years...
... fluoride use with high- risk children n Reviewing the concept of risk and defining high- risk children n Identifying risk factors and settings using fluoride interventions with high- risk children n ... interventions and should be included in the high- risk category In defining the category of high- risk children, the group questioned whether the high- risk category was in the context of a two-tier ... important to leave a Association (ADA) have developed three-tiered risk categories (low “moderate -risk category? risk, moderate risk, high risk) specific to children.17,18 Considering the target audience...
... Contents Letter High- Risk Designation Removed New High- Risk Areas Evolving High- Risk Areas Narrowing High- Risk Areas Progress Being Made in Remaining High- Risk Areas Modifying High- Risk Area Overviews ... Table 8: Changes to HighRisk List, 1990- 2013 Table 9: Areas Removed from HighRisk List, 1990- 2013 Table 10: Year That Area’s on GAO’s 2013 HighRisk List Were Designated HighRisk 28 35 39 89 ... GAO-13-283 High- Risk Series Progress Being Made in Remaining High- Risk Areas Table 3: Examples of Congressional Actions and Administration Initiatives Leading to Progress on High- Risk Areas High- risk...
... election campaign For example, activists for the Cambodia People’s Party (CPP – the ruling party) used unofficial slogans such as “Vote for CPP if you don’t want war” during the communal election campaigns ... a FIDH-OMCT / PAGE Defending Economic and Social Rights in Cambodia A High- Risk Activity final decision should be made by “higher authorities” within 24 hours This law clearly sets out a process ... 30 FIDH-OMCT / PAGE Defending Economic and Social Rights in Cambodia A High- Risk Activity Introduction Upon request of LICADHO (Cambodian League for the Promotion and Defence...
... Conflict-Affected and High- risk Areas: A Resource for Companies and Investors” aims to assist companies in implementing responsible business practices in conflict-affected and high- risk areas consistent ... Responsible Business in Conflict-Affected and High- Risk Areas Introduction The following conditions often prevail in conflict-affected and high- risk areas: human rights violations; presence of ... operational, and financial risks for companies and investors Engagement with companies operating in conflict-affected and high- risk areas can increase investors’ understanding of highly complex situations...
... fluorescence cystoscopy in select highrisk patients Materials and methods Between March 2007 and February 2008, 30 consecutive bladder cancer patients at highrisk for progression were selected ... was 67 (SD, 7.8; range, 46-76) years For 11 patients, highrisk transitional cancer was the first episode while in the remaining patients highrisk episode was recurrent (range, 2-11 resections; ... therapeutic effect of immunoprophylaxis in these highrisk patients Because bladder cancer is often multicentric, particularly when it is of high grade, a standard WL resection might miss invisible...
... and MAGI-3 represent distinct targets for highrisk HPV E6, our approach was to directly compare p53 and MAGI-3 degradation by E6 from several highrisk HPV types and further, to compare E6-mediated ... Comparison of the C-terminal PDZ-binding domains for E6 from high- risk HPV types relative to HPV-18 E6 Amino acid sequences homologous to HPV-18 are highlighted in boldy and amino acids matching the consensus ... E6 with key cellular regulatory proteins Results Comparison of p53 and MAGI-3 degradation by highrisk HPV-E6 We have previously demonstrated that HPV-18 E6 and E6GFP fusion proteins were equally...
... Herpes Gonorrheal Chamydia Group B Streptococcus Some Risk CHAPTER HIGH- RISK PREGNANCY 201 T ELBA 7-1 (Continued) Melacid dna Sur lacig Hiyrots HighRisk Hypertension (moderate to severe) Severe renal ... Chronic or acute pyelonephritis Abnormal fetal position INTRAPARTUM EV HighRisk High- risk factors above Severe PIH or eclampsia Hydraminos or oligohydramnios Amnionitis Prolonged membrane rupture ... patterns CHAPTER HIGH- RISK PREGNANCY 203 T ELBA 7-1 (Continued) INTRAPARTUM EV HighRisk Breech delivery Prolapsed cord Fetal acidosis Shoulder dystocia Maternal distress ALUATION Some Risk General...
... Fluvoxamine may prevent onset of psychosis: a case report of a patient at ultra -high risk of psychotic disorder Shigenori Tadokoro1,2,*, Nobuhisa Kanahara1, Shuichi Kikuchi2, Kenji ... patients with non-specific and psychotic-like prodromal symptoms, defined as patients at ultra -high risk (UHR) of psychotic disorder, from transitioning to psychosis However, the mechanism of such ... emerging evidence that antidepressants may be effective in preventing patients who are at ultra -high risk (UHR) of psychotic disorder from transitioning to psychosis [1] However, it is still unknown...
... M:F) with high- risk cutaneous SCC underwent SLN biopsy (mean age = 72 years, range 5189 years) All patients had at least two previously described high- risk factors, two patients had high- risk factors, ... with a high- risk recurrent SCC of the right temple developed a second local recurrence 15.2 months following narrow-margin excision with negative SLN biopsy A second patient with a high- risk large ... other hand, SLN biopsy for patients with high- risk lesions of the trunk and extremities (N = 49) had a noticeably lower NPV of 95.2% Two patients in this high- risk group developed recurrent nodal...
... an observed failure rate of 5%, while the higher risk group had a 13% risk for local-regional failure The high intermediate risk patients were also at risk for failing distantly, with a 48-month ... Oncology 2006, 1:24 http://www.ro-journal.com/content/1/1/24 Overall survival by risk group group risk 1,0 low riskhighrisk 0,9 1,00-censored 2,00-censored 0,8 % Survival 0,7 0,6 0,5 0,4 agent doxorubicin, ... attempts to identify subgroups of patients at higher risk for recurrence In the GOG study [11], a "high intermediate" group was defined by a combination of risk factors that included advanced age,...
... (1.8–2.0 Gy per fraction) in intermediate and high- risk prostate cancer patients The increasingly higher doses also intensifies toxicities to the organs at risk (OARs) which can be partially overcome ... Results Organs at risk DVH characteristics were compared for the rectum, bladder, femoral heads, and small bowel (Table 7) The 3DCRT plan generated the highest dose to all the organs at risk The dIMRT/HT ... targets all the tissue within the pelvis aside from the organs at risk; it necessarily delivers a higher dose to the organs at risk when compared to conformal pelvic vessel targeting unless they...
... shown to detect subtype A of HIV-2 by nucleic acid amplification [36] Similarly, the Roche Amplicor assay was able to detect three of four HIV-2 samples [37] Neither the branched DNA nor other RT-PCR ... from endemic areas; 4) Are children of women with risk factors for HIV-2 infection As sometimes clinical history is not available in patients with a high- suspicion for HIV infection and negative ... approved assays for the quantification of HIV RNA Assay AMPLICOR [39,40] Versant HIV-1 RNA 3.0 [41] NucliSens HIV RNA QT [28,43] COBAS AmpliPrep, Taqman HIV-1 [44] RealTime HIV-1 [45] Manufacturer...
... statin treatment was associated with an increase in mortality in the subset of highrisk patients with an estimated risk of mortality of 6% and greater Multivariate regression analysis was also ... effect was seen in all groups, but was most notable in the highrisk cohort (12.9% vs 5.6%, p < 0.05), where the predicted mortality was 6% and higher This study was not designed to explain how statins ... ranges between and 20 with a lower score predicting lower operative mortality In this study, highrisk patients were defined as those with a CRS of or above (predicted mortality of at least 6%)...
... conditions by individualized care planning and monitoring (Figure 1) Patients with a predicted highrisk of future healthcare utilization, but manageable disease burden, were found to benefit most ... identify as precisely as possible patients most likely to benefit from these programs Finding high- risk patients in computerized medical record systems, using predictive modelling, has been evaluated ... [17] Hospitalisations may be avoidable by coordinated and structured chronic care Many of the high- risk patients suffering from any of these index conditions will have additional co-morbidities...
... disease- or condition-specific QUERI Centers and utilize a standard six-step process: 1) Identify high- risk /high- volume diseases or problems 2) Identify best practices 3) Define existing practice patterns ... formative evaluations Implementation Intervention Purpose of implementation intervention Examples of FE questions Examples of FE data and their use Reminder letters Information to patients Specific information ... and described in more detail in previous publications [1,2] The Series' introductory article [3] highlights aspects of QUERI that are related specifically to implementation science, and describes...
... group at highrisk was smaller than disease risk We show that in addition to a smaller size of the highrisk group and high OR for the risk factors, a high AUC is needed to obtain a high PPV ... remained low even for high AUC because, by definition, the high- risk group was rarer than the disease (Figure 4a) When the frequency of the high- risk group was higher than the disease risk, sensitivity ... frequency of the high- risk group is lower than, equal to or higher than the disease risk The frequency of the high- risk group is defined as the proportion of individuals with a number of risk alleles...
... disease- or condition-specific QUERI Centers and utilize a standard six-step process: 1) Identify high- risk /high- volume diseases or problems 2) Identify best practices 3) Define existing practice patterns ... formative evaluations Implementation Intervention Purpose of implementation intervention Examples of FE questions Examples of FE data and their use Reminder letters Information to patients Specific information ... and described in more detail in previous publications [1,2] The Series' introductory article [3] highlights aspects of QUERI that are related specifically to implementation science, and describes...