... inaccurate that it generates new mutants for virtually every virion produced in an infected individual, thus, creating a myriad of new and unique viral particles every day [3] A high number of recombination ... keep continually damaging or killing the cells of the immune system (mainly CD4+ lymphocytes) and, thus progressively Page of (page number not for citation purposes) Virology Journal 2006, 3:60 destroy ... to mutate and revert to pathogenic variants The safety concerns over this modality killed the enthusiasm among investigators for pursuing it as a vaccine approach Furthermore, chemically inactivated...
... achievement of organizational objectives Managerial control is meaningless without managerial planning Thus, planning is the king-pin function around which other functions are designed Resource Allocation: ... that plan also become available, accessible Not planning causes: - Long transitions and waning enthusiasm - Unnecessary stress - Possibility of behavioral challenges due to waiting - An activity...
... greatly on the value which is placed on life itself If it is thought that being brought to birth and thus enabled to have the experience of being alive is usually a valuable and positive experience, ... even though it is not possible for that particular individual to avoid the condition in question Thus, for Harris, to be born with any impairment that one could have a rational preference to be ... rather than in an ‘unharmed’ state, is to make the world a worse place than it need have been and is thus morally wrong proportionately to the degree of gratuitous harm created If the disabling condition...
... almost exclusively diacyl-type molecular species (> 98% of total species) The HPLC profile, and thus the composition of DAG species, was not altered when cultures were treated with insulin (100 ... molecular species of DAG (18:0/20:4 and 18:0/20:5), while one species was decreased (18:1/18:1) Thus, insulin indeed mimicked the effects of ATP and PLC although the changes were smaller, i.e ... significantly decreased by the transfection agents as well as by the control ODN alone (results not shown) Thus, Ó FEBS 2003 Insulin signalling in rat hepatocytes (Eur J Biochem 270) 4641 Fig HPLC profile...
... VIHN [11] and the DAHam complexes of Cu(II) and Ni(II) [31] were studied previously Tables and thus present only the novel data: protonation constants for DAHKam and VIHN, and stability constants ... titrations had to be assured by recording the spectra periodically Quantitation of sites I and II (and thus of albumin concentrations) could be obtained from Cu(II) titrations, as described in our previous ... experiments (see below) The 2KNi value for BSA was obtained with site I occupied by Cu(II), and thus could be derived directly from tting the titration curves The values of 2KNi constants were...
... properties of the factor As shown in Fig 1A, the tagged wild-type protein was able to bind to ribosomes Thus, the C-terminal tag did not prevent ribosomal binding Furthermore, all mutant forms of eEF2 ... Fig 3B, the doubling rate was only marginally affected by the presence of a nonfunctional eEF2 Thus, there was no negative effect on the growth rate caused by the presence of the nonfunctional ... expressing the tagged wildtype eEF2 and showed a slight decrease in the number of viable cells Thus, T58 could be replaced by valine whereas the T56V mutation resulted in a nonfunctional eEF2...
... be accomplished HypC was also shown to form a complex with the large subunit of the hydrogenase, thus serving as a kind of chaperone [9,10] In Thiocapsa roseopersicina, two homologues of HypC have ... These residues have been shown to bind up to 18 nickel ions per dimer in Bradyrhizobium japonicum, thus functioning as a storage site [12] The C-terminal domain has a high similarity to GTPases HypB ... hypB2::Km and DhupE None of the other mutants exhibited hydrogenase activity (Fig 1A) It could thus be concluded that all of the investigated hyp genes, apart from hypA2 and hypB2, are essential...
... c/c, thus with rightelimination we get s oc+ H s/a Grammar G + assigns a to a, thus (s oc+)oa H s By associativity and commutativity any permutation of this sequent will also derive s, thus any ... replaced through dot-elimination by a Thus (s o operm c(i times) oa Hs is obtained, and any permutation of this as well, by commutativity and associativity Thus U{(s, a, c i + )Perm I, < < n} C ... learnable because the input to the learner can never provide enough information to justify convergence Thus even allowing a non-computable learning function makes no difference in such a case, and establishing...
... through “Instead, it’s a matter of fi nding what distinguishes them and makes them interesting and thus makes people want to choose them,” he says “The challenge in all branding work is to whittle ... product developers monitor new trends and analyze how they might affect the shape of underwear – and thus liners and sanitary pads “We regularly purchase undergarments to study how the cut and fit are ... modern version of the ancient wineskin, a leather pouch that collapses as the wine is emptied, thus preventing air from reaching the wine The modern container is made partly of plastic Bag-in-box...
... aspects needed to take Leading the Starbucks Way from idea to reality Thanks for your patience, enthusiasm, insights, and diligence Lynn Stenftenagel has worked on five books with me, starting with ... Connection A couple in Switzerland make their first visit to a Starbucks® store and are welcomed enthusiastically When asked what they’d like to have prepared for them, they both respond that they ... serve “Savor and Elevate” is a business principle that emphasizes the importance of maximizing enthusiasm for the products, services, and experiences your company provides It reflects the importance...
... disdain for the idea of quality within the culture of web 2.0 enthusiasts that it‟s hard to choose an example I‟ll choose hive enthusiast Clay Shirky‟s idea that there is a vast cognitive surplus ... intelligence as real requires people to reduce their mooring to reality A significant number of AI enthusiasts, after a protracted period of failed experiments in tasks like understanding natural language, ... importance of enshrining the edges between individual authors It was no use Doctrinaire web 2.0 enthusiasts only perceived that Updike was being sentimental about an ancient technology The approach...