Thể loại vật liệu sản xuất nước hoa222

loi:Vt liu sn xut nc hoa222 Mc lc Hu 1.1 c im 1.2 Vic nuụi trng Vit Nam 1.3 Hỡnh nh 1.4 Chỳ thớch 1.5 Xem thờm Long diờn hng 2.1 Hỡnh thnh 2.1.1 Lch s v nhng ng nhn v s hỡnh thnh 2.2 Tớnh cht vt lý 2.3 Tớnh cht húa hc 2.4 S dng 2.5 Chỳ thớch 2.6 am kho 2.7 Liờn kt ngoi Long nóo 3.1 hũa tan 3.2 S dng 3.3 c tớnh hc 3.4 Phn ng 3.5 Tng hp sinh hc 3.6 am kho Nardostays jatamansi 4.1 Hỡnh nh 4.2 Chỳ thớch 4.3 Liờn kt ngoi Opopanax 5.1 Hỡnh nh 5.2 Chỳ thớch 5.3 am kho i ii MC LC Pelargonium graveolens 10 6.1 Hỡnh nh 10 6.2 Chỳ thớch 10 6.3 Liờn kt ngoi 10 ng hoc hng 11 7.1 Chỳ thớch 11 7.2 Liờn kt ngoi 11 Raspberry ketone 12 8.1 Trong t nhiờn 12 8.2 iu ch 12 8.3 ng dng 12 8.4 Chỳ thớch 12 8.5 Liờn kt ngoi 13 8.6 Ngun, ngi úng gúp, v giy phộp cho bn v hỡnh nh 14 8.6.1 Vn bn 14 8.6.2 Hỡnh nh 14 8.6.3 Giy phộp ni dung 15 Chng Hu Hu cũn gi l d lai hng (thm ban ờm) hoc ờm c bit l hoa hu th phn nh bm ờm, nờn v lai hng (thm lỳc ma)[2] (danh phỏp hai phn: phi n vo ban ờm thu hỳt nhng loi cụn trựng Polianthes tuberosa), l mt loi hoa c bit, n v ny ờm, cú kh nng ta hng v ban ờm vi mựi hng ngo ngt Vit Nam, hoa hu dựng cm cỏc dp cỳng, l, cũn gi l hu ta, phõn bit vi hoa hu bc tranh ni ting "iu n bờn hoa hu" l hu tõy (Lilium longiorum), hay cũn gi l hoa loa kốn 1.1 c im 1.2 Vic nuụi trng Vit Nam Hoa hu thuc h ựa (Agavaceae), hỡnh dỏng ging cõy ti Hoa hu cú hai ging, hu n cũn gi l hu Vit Nam, hoa hu l th hoa c dựng nhiu x, cõy thp hoa ngn v tha Hu kộp cũn gi l hu vic cỳng, l m ớt dựng tng Cm hu vo t din, cõy cao, hoa dy v bụng di hn bỡnh nờn chõn hoa v thay nc hng ngy gi Hai ging ny cú th phõn thnh nhiu loi ú hoa c lõu Nc cm hoa nờn nh vi git thuc tớm cú hu trõu cao khong 1,5- 1,6 bụng di Hu ta hay thuc dit khun gõy thi chõn hoa bụng ngn, thng n trờn cõy, cú mựi thm, ngoi Hoa Hu c trng nhiu ti Bc v mt s vựng cũn cú hu Trung Hoa hu c tiờu th nhiu nht vo l hi, i chựa sau tt õm lch Vit Nam Hoa hu cú mu trng, bao hoa hỡnh phu, hng ngo ngt, to hng v ban ờm Nhiu ngi cho rng Hin nay, hu ang c trng ch yu cỏc tnh phớa hng thm ca hu khụng tt cho sc kho nờn ớt Bc Vit Nam, c bit l cỏc vựng trng hoa lõn cn cm hu phũng ng H Ni Cõy hoa hu l cõy a ỏnh sỏng, cho hoa quanh nm Dựng hoa hu cỏc dp l tt ó l mt thúi quen Tuy nhiờn, hoa hu n ch yu vo hố cũn tiờu dựng ca Vit Nam vỡ vy nhu cu tiờu th hoa hu rt ln Tuy nhiờn, quỏ trỡnh th hoỏ nờn din ụng cho ớt hoa, hoa nh, bụng ngn hn Hoa hu cú cu to cỏnh khỏ c bit, khụng khớ cú tớch trng Hu õy ó b thu hp nhanh chúng, m cao, nhng khớ khng (l trao i khớ) trờn cỏnh ú nhu cu v hoa Hu trờn th trng ngy cng gia tng vỡ vy giỏ hoa Hu nhiu nm mc cao hoa t ng m to du thm thoỏt ngoi Ban ờm khụng cú nng, nhng m khụng khớ li cao hn Trung bỡnh t 10 15 nghỡn mt chc, c bit ban ngy, cho nờn cỏc khớ khng m to cho mựi thm cỏc dp l, tt giỏ hoa cú th tng gp ri n gp ụi thoỏt (m tỳi thm) Chớnh vỡ th, ban ngy hoa hu Mi so Hu sau tr i mi chi phớ khong triu ch to hng thoang thong, nhng ban ờm nú li ng, thu tin lói t n 10 triu ng mt nm Nu thm ngo ngt thi tit thun li cú th thu lói c 15 n 20 triu Hoa hu to mựi thm theo m, vỡ vy khụng ch ng/so ban ờm, m vo ban ngy, k c tri ma, m Nhiu nụng dõn cỏc tnh lõn cn thnh ph H Chớ khụng khớ cao, hoa hu cng thm hn ngy nng.[2] Minh ó chuyn sang trng hoa hu ỏp ng nhu Tp tớnh n v ờm ca hu hỡnh thnh qua quỏ trỡnh cu th trng Ti ng Nai, Bỡnh Dng, B Ra tin húa tin hoỏ Do hoa ta mựi thm thu hỳt Vng Tu nhiu h dõn ó thay i nh trng hoa Hu cụn trựng n th phn, trỡ nũi ging, vỡ vy hoa Hoa hu cng c coi l nguyờn liu ch bin mt th phn nh vo cỏc loi cụn trựng hot ng vo ban s mún n b dng CHNG HU 1.3 Hỡnh nh 1.4 Chỳ thớch [1] e Plant List: A Working List of All Plant Species Truy cp ngy thỏng nm 2014 [2] http://vnexpress.net/GL/Khoa-hoc/Ban-co-biet/2004/ 10/3B9D79E1/ 1.5 Xem thờm Chng Long diờn hng tng, long diờn hng khụng c nụn t cỏ nh tỏng m c bi tit cựng vi phõn v cú mựi tng t mi c thi ra.[1][2] Nhiu gi thuyt cho rng ú l cht tit bao bc nhng thc n khú tiờu nh rng ca mt s loi mc, nhng cng cú thuyt cho rng cht tit ny nh mt loi khỏng sinh lm lnh nhng vt thng rut ca cỏ nh tỏng Long diờn hng sau ú c nụn hoc bi tit ngoi hay nú thoỏt bin sau cỏ nh tỏng cht v xỏc b phõn hy 2.1.1 Lch s v nhng ng nhn v s hỡnh thnh Bn v mt cc long diờn hng nm 1753 Long diờn hng l mt cht sỏp mu xỏm c to h tiờu húa ca cỏ nh tỏng Trc õy, long diờn hng c s dng ngnh cụng nghip sn xut nc hoa, nhng ngy nú ó c thay th phn ln bng vt liu tng hp v ch cũn c s dng mt s loi nc hoa t tin Long diờn hng ó c bit n t th k th 10 T nhng bỏo cỏo cú c t cỏc thng gia v thy th, du hnh gia ngi Rp Al-Masudi ó cho rng long diờn hng l mt loi nm mc di ỏy bin b bóo bt gc v trụi dt vo b bin Lý thuyt v s hỡnh thnh ny tn ti th k Ngi Rp tin rng long diờn hng c chy t cỏc sui gn b bin Trong cõu chuyn c tớch Ngn l mt ờm, nhõn vt Sinbad b m tu v trụi dt vo mt hoang o, ni õy phỏt hin mt sui chy long diờn hng 2.1 Hỡnh thnh Khong nm 1000 CN, c th Trung c t tờn cho cht ny l long diờn hng (bớnh õm:Lúngxiỏnxing, zh: ) v miờu t nú l mt loi nc bt ca rng, bi vỡ ngi ta tin rng cht ny cú ngun gc t nc bt ca rng ang nm ng gn bin tit ra.[3] Marco Polo l ngi u tiờn ghi nhn long diờn hng l mt cht bi tit ca cỏ nh tỏng sau ụng quan sỏt cỏ nh tỏng nụn cht ny mt cuc sn mc gn qun o Socotra n Dng Nm 1783, nh thc vt hc Joseph Banks mt tỏc phm ca mỡnh ó mụ t nhng quan nim sai lm ph bin v long diờn hng Tõy u v ngun gc Long diờn hng nguyờn gc ca mt cỏ nh tỏng ca cht ny ễng xỏc nh rng nú l mt sn phm Long diờn hng c to thnh h tiờu húa ca sn sinh t phn rut b phỡnh to ca mt cỏ nh cỏ nh tỏng nhng chớnh xỏc quỏ trỡnh hỡnh thnh nh tỏng ang bnh th no thỡ cha c khỏm phỏ Khỏc vi nhiu ngi Hai nh húa hc ngi Phỏp, Joseph Bienaimộ CHNG LONG DIấN HNG Caventou v Pierre Joseph Pelletier l nhng ngi u diờn hng s cú th giỳp trỏnh b lõy nhim bi vỡ tiờn s dng long diờn hng lm cht nn nc h cho mựi thm ca nú cú th xua i chng khớ gõy hoa bnh Cht ny cng tng c s dng nh mt hng liu cho thc phm, v cht kớch dc Trong thi Trung 2.2 Tớnh cht vt lý c, ngi chõu u s dng long diờn hng nh mt loi thuc cha nhc u, cm, ng kinh, v cỏc bnh Long diờn hng thng c tỡm thy dng tng, khỏc.[3] cc vi nhiu kớch thc v hỡnh dng khỏc Long diờn hng cú giỏ rt cao Giỏ ca long diờn Khi lng ca nú dao ng t 15 g (~ẵ oz) n 50 hng vo thi im nm 2012 l 20 USD/gam, bng kg (110 pound) hay thm l hn th Khi mi c 2/3 giỏ vng.[8] ly t c th cỏ nh tỏng, tin cht dng cht bộo ca long diờn hng cú mu trng nht, ụi im vi vt en, mm v cú mựi phõn rt nng Sau nhiu 2.5 Chỳ thớch thỏng hay nhiu nm b ụxi húa v gim cp quang húa (Photodegradation) bin khi, tin cht ny chuyn sang mu xỏm m hay en vi mt kt cu dng sỏp [1] Christopher Kemp (2006) Floating Gold: A Natural (and Unnatural) History of Ambergris University of Chicago v cng giũn vi hng thm rt k l bao gm cú mựi Press tr 12 t, mựi bin v mựi ca ng vt Mựi ca long diờn hng c miờu t ging nh mt phiờn bn mựi nh [2] Peter Smith (ngy 12 thỏng nm 2012) A Taste of Edible Feces Smithsonian nhng nh isopropanol m khụng cú mựi hc v khú chu Trong iu kin ó trng thnh,long diờn hng cú t trng khong 0,780 v 0,926 Nú núng chy 62 bỏch phõn v tr thnh mt cht lng dng nha cõy cú mu vng 100 (212 ) thỡ nú bay hi, to thnh mt ln hi cú mu trng Long diờn hng tan c dietyl ete v du [3] Strange but True: Whale Waste Is Extremely Valuable: Scientic American Sciam.com Ngy 26 thỏng nm 2007 Truy cp ngy 14 thỏng nm 2010 [4] Perfume Shrine: Ambrox/Ambroxan: a Modern Fascination on an Elegant Material Truy cp thỏng 10 nm 2015 [5] Kieran Mulvaney (ngy thỏng nm 2012) eres Gold in at ar Whale Poop Discovery 2.3 Tớnh cht húa hc Long diờn hng tr vi axớt Nhng tinh th ambrein mu trng cú th c tỏch long diờn hng nu ta nung núng long diờn hng cn v ngui ễxi húa ambrein cú th sn sinh ambrox v ambrinol, hai thnh phn chớnh to mựi hng ca long diờn hng Ambroxan, hin c dựng rng rói ngnh sn xut nc hoa, l mt nhng cht húa hc ngi iu ch cú tớnh cht mụ phng theo long diờn hng t nhiờn.[4] 2.4 S dng Cng nh x hng, ngi ta bit nhiu n long diờn hng thng ch yu l nú c dựng vic sn xut nc hoa.[5] Long diờn hng ó b cm s dng nhiu quc gia nhng nm 1970, ú cú Hoa K, bi vỡ ngun gc ca nú l t cỏ nh tỏng, l mt loi d b tn thng.[6] Ngi Ai Cp c t long diờn hng xụng thm, cũn ngi Ai Cp hin i thỡ s dng nú cỏc loi thuc lỏ thm.[7] Trong i dch Cỏi cht en chõu u, ngi ta tin rng nu mang theo mt qu cu long [6] IUCN Redlist [7] Brady, George Stuart; Clauser, Henry R.; Vaccari, John A (2002) Materials Handbook: An Encyclopedia for Managers, Technical Professionals, Purchasing and Production Managers, Technicians, and Supervisors United States: McGraw-Hill Professional tr 64 ISBN 978-0-07-136076-0 [8] Eric Spitznagel (ngy 12 thỏng nm 2012) Ambergris, Treasure of the Deep BusinessWeek 2.6 Tham kho Borschberg, Peter, O comộrcio de õmbar asiỏtico no inớcio da ộpoca moderna (sộculos XV-XVIII) e Asiatic ambergris trade in the early modern period (15 to 18 century)" Oriente, Lisbon: Fundaỗóo Oriente, vol 8, April 2004, pp 325 Kemp, Christopher (ngy 15 thỏng nm 2012) Floating Gold: A Natural (and Unnatural) History of Ambergris University of Chicago Press ISBN 9780226430362 Alain Corbin: Pesthauch und Blỹtendu: Eine Geschichte des Geruchs (Originaltitel: Le miasme et la jonquille Aubier Montaigne, Paris 1982 2.7 LIấN KT NGOI ĩbersetzt von Grete Osterwald), Wagenbach, Berlin 2005 (Erstausgabe 1984), ISBN 978-3-80313618-3 Sabine Krist/Wilfried Grieòer: Die Erforschung der chemischen Sinne Geruchsund Geschmackstheorien von der Antike bis zur Gegenwart Lang, Frankfurt am Main / Berlin / Bern / Bruxelles / New York / Oxford / Wien 2006, ISBN 978-3-631-55284-1 Gisela Reinecke, Claudia Pilatus: Parfum - Lexikon der Dỹe Komet, Kửln 2006, ISBN 978-3-89836596-3 Renate Smollich: Der Bisamapfel in Kunst und Wissenscha Deutscher Apotheker Verlag, Stugart 1983, ISBN 3-7692-0733-5, S 2630 (zur Geschichte des Dustos) Bernd Schọfer (thỏng 12 nm 2011) Ambrox: Unwiderstehliche Dunote Chemie in unserer Zeit 45 (6) (Weinheim: Wiley-VCH Verlag) tr 374388 ISSN 0009-2851 doi:10.1002/ciuz.201100557 2.7 Liờn kt ngoi Natural History Magazine Article (from 1933): Floating Gold e Romance of Ambergris Ambergris - A Pathnder and Annotated Bibliography On the chemistry and ethics of Ambergris Scientic American Strange but True: Whale Waste Is Extremely Valuable e Origin of Ambergris excerpted from Floating Gold by Christopher Kemp Tr thnh t phỳ phỳt chc nh nht c cc vng Bỏo Dõn trớ online Chng Long nóo Long nóo hay cũn gi l bng phin l mt cht rn kt tinh mu trng hay sut ging nh sỏp vi mựi thm hng mnh c trng Nú l mt loi terpenoid vi cụng thc húa hc C10 H16 O Nú c tỡm thy g ca cõy long nóo (Cinnamonum camphora), mt loi cõy thõn g ln thng xanh, mc chõu , c bit l Borneo, Indonesia v mt vi loi cõy g cú quan h h hng khỏc h Nguyt qu, ỏng chỳ ý l Ocotea usambarensis ụng Phi Nú cng cú th c tng hp t nha thụng Nú c s dng vỡ mựi ca nú, vai trũ ca cỏc cht lng p v cho cỏc mc ớch y hc v cú tỏc dng nh l mt cht gõy tờ v kh trựng nh cc b Nú cng th ung vi lng nh (50 mg) i vi cỏc triu chng bnh tim nh cng nh mt mi Long nóo cng c s dng nh l mt loi hng liu cỏc loi ngt n v chõu u Ngi ta cng cho rng long nóo ó tng c dựng lm hng liu cỏc loi bỏnh ko tng t nh kem Trung c thi k nh ng Trong cỏc l t puja ca o Hindu, long nóo cng c dựng thp sỏng ngn la cho nghi l aarti Long nóo c Gustaf Komppa tng hp nhõn to ln u tiờn vo nm 1903 Trc ú, mt s hp cht hu c (chng hn urờ) cng ó c tng hp phũng thớ nghim, nhng ú long nóo l mt sn phm ớt cú t nhiờn v li vi nhu cu rng khp th gii nờn nú ó c Komppa bt u sn xut quy mụ cụng nghip ti Tainionkoski, Phn Lan nm 1907 nh l cht tng hp ton phn cụng nghip u tiờn 3.3 c tớnh hc Vi mt lng ln, nú l mt cht gõy ng c nut phi v cú th gõy tai bin ngp mỏu, ri lon, kớch thớch v hiu ng thỏi quỏ Nm 1980, FDA Hoa K ó t gii hn 11% long nóo cho phộp cỏc sn phm tiờu dựng v cm ton b cỏc sn phm dỏn nhón l camphorated oil, camphor oil, camphor liniment, camphorated liniment (cỏc loi du long nóo) (nhng long nóo li khụng cú mt white camphor essential oil"-tinh du long nóo trng) 3.1 hũa tan Long nóo hũa tan kộm nc, ch khong 0,12 g/100 ml nc 25 nhng nú hũa tan khỏ tt cỏc dung mụi khỏc nh axớt axetic (~200 g/100 ml), ờtanol (~100 g/100 ml), axờton (~250 g/100 ml), ờte (~100 g/100 ml) hay clorofom (~200 g/100 ml) iu kin tng t 3.4 Phn ng Cỏc phn ng in hỡnh m long nóo tham gia l: 3.2 S dng Brụm húa Ngy long nóo c s dng lm tỏc nhõn lm mm cho xenluloza nitrat, cng nh lm cỏc viờn bng phin chng cụn trựng lm hi qun ỏo, cng nh l cht kh trựng, p thm v cỏc loi phỏo hoa Cỏc tinh th long nóo cng c dựng ngn chn thng tn b cỏc loi cụn trựng nh cn Mt s dng thuc m chng nga cú s dng long nóo nh l thnh phn hot tớnh ch yu Nú cng c s dng y hc Long nóo d dng hp th qua da v to cm giỏc mỏt tng t nh tinh du bc h (menthol) ễxi húa bng axớt nitric 3.6 THAM KHO Chuyn húa thnh isonitrosocamphor Long nóo cng cú th b kh thnh isoborneol bng bohirua natri 3.5 Tng hp sinh hc Trong tng hp sinh hc, long nóo c sn xut t geranyl pyrophotphat, thụng qua úng vũng ca linaloyl pyrophotphat thnh bornyl pyrophotphat, tip theo l thy phõn thnh borneol v ụxi húa thnh long nóo Tng hp sinh hc ca long nóo t geranyl pyrophotphat 3.6 Tham kho J Mann, R S Davidson, J B Hobbs, D V Banthorpe, J B Harborne, Natural Products, cỏc trang 309-311, Addison Wesley Longman Ltd., Harlow, UK, 1994 ISBN 0-582-06009-5 Handbook of Chemistry and Physics, CRC Press, Ann Arbor, Michigan e Merck Index, n bn ln th 7, Merck & Co, Rahway, New Jersey, Hoa K, 1960 Chng Nardostachys jatamansi D liu liờn quan ti Nardostachys jatamansi ti Wikispecies Nardostays jatamansi l mt loi thc vt cú hoa h Kim ngõn Loi ny c (D Don) DC mụ t khoa hc u tiờn nm 1830.[3] 4.1 Hỡnh nh 4.2 Chỳ thớch [1] TPL, treatment of Nardostachys jatamansi e Plant List; Version (published on the internet) Royal Botanic Gardens, Kew v Missouri Botanical Garden (MOBOT) 2010 Truy cp ngy 16 thỏng nm 2013 [2] Patrinia jatamansi (the basionym of Nardostachys jatamansi) was originally described and published in Prodromus Florae Nepalensis 159 1825 Name - Patrinia jatamansi D.Don Tropicos Saint Louis, Missouri: MOBOT Truy cp ngy 16 thỏng nm 2013 [3] e Plant List (2010) Nardostachys jatamansi Truy cp ngy 18 thỏng nm 2013 4.3 Liờn kt ngoi Phng tin liờn quan ti Nardostachys jatamansi ti Wikimedia Commons Chng Opopanax Opopanax l chi thc vt cú hoa h Apiaceae.[1] 5.1 Hỡnh nh 5.2 Chỳ thớch [1] Opopanax e Plant List Truy cp ngy 16 thỏng nm 2013 5.3 Tham kho Phng tin liờn quan ti Opopanax ti Wikimedia Commons D liu liờn quan ti Opopanax ti Wikispecies Chng Pelargonium graveolens Pelargonium graveolens l mt loi thc vt cú hoa h M hc Loi ny c L'Hộr mụ t khoa hc u tiờn nm 1792.[2] 6.1 Hỡnh nh [2] e Plant List (2010) Pelargonium graveolens Truy cp ngy 28 thỏng nm 2013 6.3 Liờn kt ngoi Phng tin liờn quan ti Pelargonium graveolens ti Wikimedia Commons D liu liờn quan ti Pelargonium graveolens ti Wikispecies Vn thc vt hong gia Kew; i hc Harvard; Australian Plant Name Index (biờn tp) Pelargonium graveolens International Plant Names Index Truy cp ngy 28 thỏng nm 2013 6.2 Chỳ thớch [1] USDA ARS NPGS Pelargonium graveolens information from NPGS/GRIN United States Department of Agriculture (USDA), Agricultural Research Service (ARS), National Plant Germplasm System (NPGS) Truy cp ngy 23 thỏng nm 2007 10 Chng Qung hoc hng ng hoc hng, hay ngn gn l hoc hng (tờn khoa hc: Pogostemon cablin (Blanco) Benth), l loi thc vt thuc chi Pogostemon, h Bc h Cõy cú th cao n 0,75 m), hoa mu trng hng nht õy l loi bn a ca chõu nhit i, hin c trng Trung c, Indonesia, n , Malaysia, Mauritius, Philippines, ỏi Lan, Vit Nam v Tõy Phi [4] Nikiforov, Alexej et al; Jirovetz, Leopold; Buchbauer, Gerhard; Raverdino, Viorio (1988) GC-FTIR and GCMS in odour analysis of essential oils Microchimica Acta 95 (1 - 6): 193198 doi:10.1007/BF01349751 7.2 Liờn kt ngoi Pogostemon cablin, P commosum, P hortensis, P heyneasus v P plectranthoides u l cỏc ging cõy trng cho tinh du hoc hng (ting Anh: patchouli oil) Tinh du hoc hng c chit bng cỏch chng ct hi nc Cỏc thnh phn to hng tinh du hoc hng: Germacrene-B [1] Patchoulol [2][3][4] Norpatchoulenol [4] Tinh du hoc hng c dựng sn xut nc hoa, dc phm, thuc tr sõu, cht thm, thuc dng túc 7.1 Chỳ thớch [1] Hasegawa, Yoshihiro; Tajima, Katsuhiko; Toi, Nao; Sugimura, Yukio v ng nghip (1992) An additional constituent occurring in the oil from a patchouli cultivar Flavour and Fragrance Journal (6): 333335 doi:10.1002/.2730070608 [2] Weyerstahl, Peter; Gansau, Christian; Marschall, Helga v ng nghip (1993) Structure-odour correlation Part XVIII Partial structures of patchoulol with bicyclo[2.2.2]octane skeleton Flavour and Fragrance Journal (6): 297306 doi:10.1002/.2730080603 [3] Hybertson, Brooks M (2007) Solubility of the Sesquiterpene Alcohol Patchoulol in Supercritical Carbon Dioxide Journal of Chemical Engineering Data 52 (1): 235238 PMC 2677825 PMID 19424449 doi:10.1021/je060358w Truy cp ngy 25 thỏng nm 2009 11 Natural Insect Repellents Repellents Natural Insect Chng Raspberry ketone Raspberry Ketone [4-(4-hydroxyphenyl) butan-2-one; RK], l mt hp cht phenol t nhiờn cú trỏi mõm xụi (red raspberry, tờn khoa hc l Rubus idaeus L.) Raspberry Ketone l hp cht lm nờn mựi hng ch yu ca mõm xụi n cú cha lng m cao Khi xem xột gc tng ng v cu trỳc, RK cú tỏc dng b góy v giỳp t m nhng t bo m Ngoi ra, cho chut c dựng RK liu cao, ngi ta ó chng minh c rng RK giỳp ngn chn tng cõn ch n quỏ nhiu cht bộo Ngoi ra, RK cũn cho thy giỳp tng ly gii m trng [8] 8.1 Trong t nhiờn Tỏc dng gim cõn v t m ca RK c cho l RK cú to nờn tỏc dng i vi Adiponectin Adiponectin l mt nhng adipocytokine quan trng nht v mụ m tit Adiponectin cú tỏc dng iu chnh quỏ trỡnh chuyn húa ca m v ng Adiponectin úng vai trũ quan trng vic iu chnh cõn nng v n nh ni mụi Nghiờn cu cho thy thnh phn ny cú liờn quan n bnh bộo phỡ v cỏc bnh v chuyn húa Khi c th bn b bộo phỡ hoc b mt loi bnh ri lon chuyn húa gõy thỡ nng Adiponectin c th s b gim[9][10] V mc tiờu ca cỏc nghiờn cu thuc v liu phỏp iu tr bnh bộo phỡ chớnh l lm tng hm lng adiponectin c tit Nghiờn cu [11] ó chng minh rng: T bo m c nuụi cy 3T3-L1 preadipocytes, sau ngy c iu tr bng 10M RK ó cho thy ó tng hm lng adiponectin c tit v hm lng adiponectin t bo thc vt, raspberry ketone c tng hp t coumaroyl-CoA[3] Mc chit xut xeton mõm xụi nguyờn cht thng l 14 mg mi kg qu mõm xụi[4] 8.2 iu ch Do phong phỳ t nhiờn ca raspberry ketone l rt thp, nú c iu ch v mt cụng nghip bng mt lot phng phỏp qua cỏc cht trung gian húa hc[5] Mt nhng cỏch ny cú th c thc hin thụng qua phn ng hydro húa xỳc tỏc aldon chộo Trong axeton v hydroxit natri, 4-hydroxybenzaldehyde cú th to thnh xeton -cha no Cht ny sau ú i qua phn ng hydro húa xỳc tỏc sn xut raspberry Nh sn xut b sung dinh dng Andrew Lessman ch ketone Phng phỏp ny cú hiu sut ti 99% trớch v phn i cỏc phng tin truyn thụng ó tip RK cú cu trỳc tng t nh cu trỳc ca capsaicin v th v li ớch gim cõn ca raspberry ketone v mnh synephyrine [6] m cnh bỏo chng li vic s dng nú.[12] 8.3 ng dng 8.4 Chỳ thớch Raspberry Ketone c s dng rng rói cụng nghip sn xut nc hoa, m phm v cũn c dựng lm mt ph gia to mựi thc phm Nú l mt cỏc thnh phn to hng v t nhiờn t tin nht c s dng cụng nghip thc phm Hp cht t nhiờn ny cú th cú giỏ thnh cao ti $20.000 cho mi kg.[4] Nm 1965, Cc n lý c phm v Dc phm Hoa K xp raspberry ketone vo loi hp cht cụng nhn l an ton (GRAS = Generally Recognised As Safe)[7] Capsaicin v synephrine ó c bỏo cỏo l cú tỏc dng b góy m, t m nhng chut c cho n thc 12 [1] Catalog of Organics and Fine Chemicals, Acros Organics, 2004/05, page 1250 [2] Opdyke, D L J (1978) 4-(p-Hydroxyphenyl)2butanone Fd Cosmet Toxicol 16: 781782 doi:10.1016/S0015-6264(78)80113-8 [3] MetaCyc Pathway: raspberry ketone biosynthesis [4] Beekwilder, J.; Van der Meer, I.; Sibbesen, O.; Broekgaarden, M.; Qvist, I.; Mikkelsen, J.; Hall, R (2007) Microbial production of natural raspberry ketone Biotechnol J (10): 12701279 PMID 17722151 doi:10.1002/biot.200700076 8.5 LIấN KT NGOI [5] Tateiwa, J.-I., Horiuchi, H., Hashimoto, K., Yamauchi, T., and Uemura, S (1994) Cation-exchanged montmorillonite-catalyzed facile Friedel-cras alkylation of hydroxy and methoxy aromatics with 4-hydroxybutan-2-one to produce raspberry ketone and some pharmaceutically active compounds J Org Chem 59 (20): 59015904 doi:10.1021/jo00099a017 [6] Harada N, Okajima K, Narimatsu N, Kurihara H, Nakagata N Eect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and on hair growth and skin elasticity in humans Growth Horm IGF Res 2008; 18: 335344 [7] Opdyke, D L J (1978) Monographs on fragrance raw materials 4-(p-Hydroxyphenyl)2-butanone Food and Cosmetics Toxicology 16 (Suppl 1): 781782 doi:10.1016/S0015-6264(78)80113-8 [8] Morimoto C, Satoh Y, Hara M, Inoue S, Tsujita T, Okuda H Anti-obese action of raspberry ketone Life Sci 2005; 77: 194204 [9] Hausman DB, DiGirolamo M, Bartness TJ, Hausman GJ, Martin JR e biology of white adipocyte proliferation Obes Rev 2001; 2: 239254 [10] Hu E, Liang P, Spiegelman BM AdipoQ is a novel adipose-specic gene dysregulated in obesity J Biol Chem 1996; 271: 1069710703 [11] Raspberry Ketone Increases Both Lipolysis and Fay Acid Oxidation in 3T3-L1 Adipocytes [12] Raspberry Ketone is not a Fat-Burning Miracle Words On Wellness Ngy 13 thỏng nm 2012 Truy cp 2012010-17 Kim tra giỏ tr ngy thỏng trong: |accessdate= (tr giỳp) 8.5 Liờn kt ngoi 13 14 CHNG RASPBERRY KETONE 8.6 Ngun, ngi úng gúp, v giy phộp cho bn v hỡnh nh 8.6.1 Vn bn Hu Ngun: https://vi.wikipedia.org/wiki/Hu%E1%BB%87?oldid=26047647 Ngi úng gúp: Nguyn anh ang, IX, TXiKiBoT, Qbot, Luckas-bot, Xqbot, Prenn, Phng Huy, Tnt1984, TuHan-Bot, EmausBot, ZộroBot, Memberofc1, ChuispastonBot, ewarm, Cheers!bot, MerlIwBot, PrennAWB, AlphamaBot, Addbot, itxongkhoiAWB, GHA-WDAS, TuanminhBot v Trantrongnhan100YHbot Long diờn hng Ngun: https://vi.wikipedia.org/wiki/Long_di%C3%AAn_h%C6%B0%C6%A1ng?oldid=24181940 Ngi úng gúp: DHN, Newone, Handyhuy, Idioma-bot, Sholokhov, AlleinStein, Rubinbot, TuHan-Bot, EmausBot, Cheers!-bot, JYBot, AlphamaBot, Addbot, itxongkhoiAWB, TuanminhBot, Vungo2004 v ngi vụ danh Long nóo Ngun: https://vi.wikipedia.org/wiki/Long_n%C3%A3o?oldid=26471214 Ngi úng gúp: Vng Ngõn H, DHN-bot, Escarbot, JAnDbot, ijs!bot, VolkovBot, TXiKiBoT, AlleborgoBot, SieBot, Loveless, Idioma-bot, MelancholieBot, SpBot, MystBot, Luckas-bot, ArthurBot, Rubinbot, Xqbot, TobeBot, TuHan-Bot, , WikitanvirBot, Anhtucxac, Cheers!-bot, MerlIwBot, TuanUt, YFdyh-bot, AlphamaBot, Addbot, , itxongkhoiAWB, Tuanminh01, TuanminhBot, Monsterian, Hunh Nhõn-thp v ngi vụ danh Nardostays jatamansi Ngun: https://vi.wikipedia.org/wiki/Nardostachys_jatamansi?oldid=25321124 Ngi úng gúp: ỏi Nhi, Newone, Qbot, Cheers!-bot, AlphamaBot, Lvp-bot, itxongkhoiAWB v TuanminhBot Opopanax Ngun: https://vi.wikipedia.org/wiki/Opopanax?oldid=21954597 Ngi úng gúp: Qbot, EmausBot, Cheers!-bot, AlphamaBot, itxongkhoiAWB v AlphamaBot4 Pelargonium graveolens Ngun: https://vi.wikipedia.org/wiki/Pelargonium_graveolens?oldid=22181140 Ngi úng gúp: Qbot, Cheers!-bot, AlphamaBot, AlphamaBot2, Lvp-bot, itxongkhoiAWB v TuanminhBot ng hoc hng Ngun: https://vi.wikipedia.org/wiki/Qu%E1%BA%A3ng_ho%E1%BA%AFc_h%C6%B0%C6%A1ng?oldid=25419303 Ngi úng gúp: ỏi Nhi, Newone, TXiKiBoT, Hungda, TuHan-Bot, EmausBot, WikitanvirBot, ewarm, Cheers!-bot, MerlIwBot, Greenknight dv, YFdyh-bot, AlphamaBot, Addbot, itxongkhoiAWB, Tuanminh01, TuanminhBot v Mt ngi vụ danh Raspberry ketone Ngun: https://vi.wikipedia.org/wiki/Raspberry_ketone?oldid=22181285 Ngi úng gúp: ỏi Nhi, Meotrangden, TuHan-Bot, DarafshBot, AlphamaBot, Addbot, Tuanminh01, TuanminhBot v Ngocminh04e 8.6.2 Hỡnh nh Tp_tin:00205_Polianthes_tuberosa.jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/4/47/00205_Polianthes_tuberosa jpg Giy phộp: CC BY 3.0 Ngi úng gúp: Tỏc phm chớnh ngi ti lờn to Ngh s u tiờn: Conoce3000 Tp_tin:Agave_americana_a-m.jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/4/4a/Agave_americana_a-m.jpg Giy phộp: CC BY-SA 3.0 Ngi úng gúp: Tỏc phm chớnh ngi ti lờn to Ngh s u tiờn: Stan Shebs Tp_tin:Ambergris.jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/b/b1/Ambergris.jpg Giy phộp: CC BY 2.0 Ngi úng gúp: Flickr image at http://www.flickr.com/photos/peterkaminski/128588176/ (more precisely, the original size image at http: //www.flickr.com/photo_zoom.gne?id=128588176&size=o) Ngh s u tiờn: Photographer: Peter Kaminski Tp_tin:Ambraklumpen_1753_01.jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/a/af/Ambraklumpen_1753_01.jpg Giy phộp: Public domain Ngi úng gúp: own reproduktion, original is more than 100 years old Ngh s u tiờn: Khụng rừ Tp_tin:Ambrein.svg Ngun: https://upload.wikimedia.org/wikipedia/commons/d/df/Ambrein.svg Giy phộp: Public domain Ngi úng gúp: ? Ngh s u tiờn: ? Tp_tin:Ambrinol.svg Ngun: https://upload.wikimedia.org/wikipedia/commons/8/83/Ambrinol.svg Giy phộp: Public domain Ngi úng gúp: Tỏc phm chớnh ngi ti lờn to Ngh s u tiờn: Yikrazuul (talk) Tp_tin:Ambrox.svg Ngun: https://upload.wikimedia.org/wikipedia/commons/d/d3/Ambrox.svg Giy phộp: Public domain Ngi úng gúp: Tỏc phm chớnh ngi ti lờn to Ngh s u tiờn: Yikrazuul (talk) Tp_tin:Camphor-3-Brominecampher.png Ngun: https://upload.wikimedia.org/wikipedia/commons/3/30/ Camphor-3-Brominecampher.png Giy phộp: CC-BY-SA-3.0 Ngi úng gúp: ? Ngh s u tiờn: ? Tp_tin:Camphor-Camphor_acid.png Ngun: https://upload.wikimedia.org/wikipedia/commons/5/57/Camphor-Camphor_acid.png Giy phộp: CC-BY-SA-3.0 Ngi úng gúp: ? Ngh s u tiờn: ? Tp_tin:Camphor-Isonitrosocamphor.png Ngun: https://upload.wikimedia.org/wikipedia/commons/2/25/ Camphor-Isonitrosocamphor.png Giy phộp: CC-BY-SA-3.0 Ngi úng gúp: ? Ngh s u tiờn: ? 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Ngh s u tiờn: SVG version was created by User:Grunt and cleaned up by 3247, based on the earlier PNG version, created by Reidab Tp_tin:Dipsacus_pilosus0.jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/e/ea/Dipsacus_pilosus0.jpg Giy phộp: CCBY-SA-3.0 Ngi úng gúp: caliban.mpiz-koeln.mpg.de/mavica/index.html part of www.biolib.de Ngh s u tiờn: Kurt Stỹber [1] Tp_tin:GeraniumEssOil.png Ngun: https://upload.wikimedia.org/wikipedia/commons/e/e9/GeraniumEssOil.png Giy phộp: Public domain Ngi úng gúp: Tỏc phm chớnh ngi ti lờn to Ngh s u tiờn: Itineranrader Tp_tin:Geranium_robertianum01.jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/0/05/Geranium_robertianum01 jpg Giy phộp: CC-BY-SA-3.0 Ngi úng gúp: ? Ngh s u tiờn: ? 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Tp_tin:Opopanax_chironium0.jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/6/6a/Opopanax_chironium0.jpg Giy phộp: CC-BY-SA-3.0 Ngi úng gúp: caliban.mpiz-koeln.mpg.de/mavica/index.html part of www.biolib.de Ngh s u tiờn: Kurt Stỹber [1] Tp_tin:Opopanax_chironium_2007-06-02_(flower).jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/b/b5/Opopanax_ chironium_2007-06-02_%28flower%29.jpg Giy phộp: CC-BY-SA-3.0 Ngi úng gúp: Magnus Manske (own work) Ngh s u tiờn: Magnus Manske Tp_tin:Opopanax_chironium_2007-06-02_(plant).jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/9/9b/Opopanax_ chironium_2007-06-02_%28plant%29.jpg Giy phộp: CC-BY-SA-3.0 Ngi úng gúp: Magnus Manske (own work) Ngh s u tiờn: Magnus Manske Tp_tin:Pelargonium_graveolens_(Rose_Geranium).jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/d/d6/ Pelargonium_graveolens_%28Rose_Geranium%29.jpg Giy phộp: CC BY-SA 3.0 Ngi úng gúp: Tỏc phm chớnh ngi ti lờn to Ngh s u tiờn: Vladimir2366fa Tp_tin:Pelargonium_graveolens_5.jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/0/0b/Pelargonium_graveolens_5 jpg Giy phộp: CC BY-SA 3.0 Ngi úng gúp: Tỏc phm chớnh ngi ti lờn to Ngh s u tiờn: Stan Shebs Tp_tin:Pittosporum_tobira1.jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/2/21/Pittosporum_tobira1.jpg Giy phộp: CC-BY-SA-3.0 Ngi úng gúp: caliban.mpiz-koeln.mpg.de/mavica/index.html part of www.biolib.de Ngh s u tiờn: Kurt Stỹber [1] Tp_tin:Pogostemon_cablin_001.jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/1/17/Pogostemon_cablin_001.jpg Giy phộp: CC-BY-SA-3.0 Ngi úng gúp: No machine-readable source provided Own work assumed (based on copyright claims) Ngh s u tiờn: No machine-readable author provided Valộrie75 assumed (based on copyright claims) Tp_tin:Question_book-new.svg Ngun: https://upload.wikimedia.org/wikipedia/commons/9/99/Question_book-new.svg Giy phộp: CC-BY-SA-3.0 Ngi úng gúp: Chuyn t en.wikipedia sang Commons Created from scratch in Adobe Illustrator Based on Image: Question book.png created by User:Equazcion Ngh s u tiờn: Tkgd2007 Tp_tin:Raspberry_ketone.png Ngun: https://upload.wikimedia.org/wikipedia/commons/9/9c/Raspberry_ketone.png Giy phộp: Public domain Ngi úng gúp: Tỏc phm chớnh ngi ti lờn to Ngh s u tiờn: Edgar181 Tp_tin:Rose_Geranium.jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/2/2f/Rose_Geranium.jpg Giy phộp: Public domain Ngi úng gúp: Tỏc phm chớnh ngi ti lờn to Ngh s u tiờn: Laitche Tp_tin:Sedap_malam.jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/1/1c/Sedap_malam.jpg Giy phộp: CC BY-SA 2.0 Ngi úng gúp: originally posted to Flir as Sedap malam Ngh s u tiờn: Eka Priatna Tp_tin:SpikenardEssentialOil.png Ngun: https://upload.wikimedia.org/wikipedia/commons/b/bb/SpikenardEssentialOil.png Giy phộp: Public domain Ngi úng gúp: Tỏc phm chớnh ngi ti lờn to Ngh s u tiờn: Itineranrader Tp_tin:Starr_070906-9086_Polianthes_tuberosa.jpg Ngun: https://upload.wikimedia.org/wikipedia/commons/e/e8/Starr_ 070906-9086_Polianthes_tuberosa.jpg Giy phộp: CC BY 3.0 Ngi úng gúp: Plants of Hawaii, Image 070906-9086 from http://www.hear.org/starr/plants/images/image/?q=070906-9086 Ngh s u tiờn: Forest & Kim Starr Tp_tin:Wiktionary_small.svg Ngun: https://upload.wikimedia.org/wikipedia/commons/f/f9/Wiktionary_small.svg Giy phộp: CC BY-SA 3.0 Ngi úng gúp: ? 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